All Stories

  1. Myosin in autoinhibited off state(s), stabilized by mavacamten, can be recruited in response to inotropic interventions
  2. Structural OFF/ON transitions of myosin in relaxed porcine myocardium predict calcium-activated force
  3. Slow-twitch skeletal muscle defects accompany cardiac dysfunction in transgenic mice with a mutation in the myosin regulatory light chain