All Stories

  1. Development of Mutant M3 Muscarinic Receptors Biased for G Protein Activation or Recruitment of β-Arrestins

    Article • Biochemistry, June 2025, American Chemical Society (ACS)

    Dr Vsevolod V Gurevich

  2. Assembling the jigsaw puzzle of life

    Article • Trends in Biochemical Sciences, May 2025, Elsevier

    Dr Vsevolod V Gurevich

  3. The Role of Individual Residues in the N-Terminus of Arrestin-1 in Rhodopsin Binding

    Article • International Journal of Molecular Sciences, January 2025, MDPI AG

    Dr Vsevolod V Gurevich

  4. Flavors of GPCR signaling bias

    Article • Neuropharmacology, December 2024, Elsevier

    Dr Vsevolod V Gurevich

  5. GPCR-dependent and -independent arrestin signaling

    Article • Trends in Pharmacological Sciences, July 2024, Elsevier

    Dr Vsevolod V Gurevich

  6. Arrestins: A Small Family of Multi-Functional Proteins

    Article • International Journal of Molecular Sciences, June 2024, MDPI AG

    Dr Vsevolod V Gurevich

  7. Arrestin‐3 binds parkin and enhances parkin‐dependent mitophagy

    Article • Journal of Neurochemistry, January 2024, Wiley

    Dr Vsevolod V Gurevich

  8. Dynamic Nature of Proteins is Critically Important for Their Function: GPCRs and Signal Transducers

    Article • Applied Magnetic Resonance, September 2023, Springer Science + Business Media

    Dr Vsevolod V Gurevich

  9. GPCR Binding and JNK3 Activation by Arrestin-3 Have Different Structural Requirements

    Article • Cells, June 2023, MDPI AG

    Dr Vsevolod V Gurevich

  10. Conformational flexibility underlies the versatility of arrestins

    Article • BioEssays, May 2023, Wiley

    Dr Vsevolod V Gurevich

  11. Functional Role of Arrestin-1 Residues Interacting with Unphosphorylated Rhodopsin Elements

    Article • International Journal of Molecular Sciences, May 2023, MDPI AG

    Dr Vsevolod V Gurevich

  12. GPCR binding and JNK3 activation by arrestin-3 have different structural requirements

    Article • May 2023, Cold Spring Harbor Laboratory Press

    Dr Vsevolod V Gurevich

  13. A boost in learning by removing nuclear phosphodiesterases and enhancing nuclear cAMP signaling

    Article • Science Signaling, March 2023, American Association for the Advancement of Science

    Dr Vsevolod V Gurevich

  14. Structural details of a Class B GPCR-arrestin complex revealed by genetically encoded crosslinkers in living cells

    Article • Nature Communications, March 2023, Springer Science + Business Media

    Dr Vsevolod V Gurevich

  15. The Role of Arrestin-1 Middle Loop in Rhodopsin Binding

    Article • International Journal of Molecular Sciences, November 2022, MDPI AG

    Dr Vsevolod V Gurevich

  16. Short Arrestin-3-Derived Peptides Activate JNK3 in Cells

    Article • International Journal of Molecular Sciences, August 2022, MDPI AG

    Dr Vsevolod V Gurevich

  17. Structural basis of GPCR coupling to distinct signal transducers: implications for biased signaling

    Article • Trends in Biochemical Sciences, July 2022, Elsevier

    Dr Vsevolod V Gurevich

  18. Solo vs. Chorus: Monomers and Oligomers of Arrestin Proteins

    Article • International Journal of Molecular Sciences, June 2022, MDPI AG

    Dr Vsevolod V Gurevich

  19. Structural Basis of Arrestin Selectivity for Active Phosphorylated G Protein-Coupled Receptors

    Article • International Journal of Molecular Sciences, November 2021, MDPI AG

    Dr Vsevolod V Gurevich

  20. Phototransduction in retinal cones: Analysis of parameter importance

    Article • PLOS One, October 2021, PLOS

    Dr Vsevolod V Gurevich

  21. Scaffolding mechanism of arrestin-2 in the cRaf/MEK1/ERK signaling cascade

    Article • Proceedings of the National Academy of Sciences, September 2021, Proceedings of the National Academy of Sciences

    Ka Young Chung, Dr Vsevolod V Gurevich

  22. Receptor-Arrestin Interactions: The GPCR Perspective

    Article • Biomolecules, February 2021, MDPI AG

    Dr Vsevolod V Gurevich

  23. GRKs as Modulators of Neurotransmitter Receptors

    Article • Cells, December 2020, MDPI AG

    Dr Vsevolod V Gurevich

  24. The finger loop as an activation sensor in arrestin

    Article • Journal of Neurochemistry, November 2020, Wiley

    Dr Vsevolod V Gurevich

  25. The Dynamics of the Neuropeptide Y Receptor Type 1 Investigated by Solid-State NMR and Molecular Dynamics Simulation

    Article • Molecules, November 2020, MDPI AG

    Dr Vsevolod V Gurevich

  26. Designer adhesion GPCR tells its signaling story

    Article • Nature Chemical Biology, September 2020, Springer Science + Business Media

    Dr Vsevolod V Gurevich

  27. Exploring GPCR‐arrestin interfaces with genetically encoded crosslinkers

    Article • EMBO Reports, September 2020, Springer Science + Business Media

    Dr Vsevolod V Gurevich

  28. Lysine in the lariat loop of arrestins does not serve as phosphate sensor

    Article • Journal of Neurochemistry, July 2020, Wiley

    Dr Vsevolod V Gurevich

  29. Phosphorylation barcode-dependent signal bias of the dopamine D1 receptor

    Article • Proceedings of the National Academy of Sciences, June 2020, Proceedings of the National Academy of Sciences

    Dr Vsevolod V Gurevich

  30. Mdm2 enhances ligase activity of parkin and facilitates mitophagy

    Article • Scientific Reports, March 2020, Springer Science + Business Media

    Dr Vsevolod V Gurevich

  31. β Cell–intrinsic β-arrestin 1 signaling enhances sulfonylurea-induced insulin secretion

    Article • Journal of Clinical Investigation, August 2019, American Society for Clinical Investigation

    Dr Vsevolod V Gurevich

  32. Critical role of the finger loop in arrestin binding to the receptors

    Article • PLOS One, March 2019, PLOS

    Dr Vsevolod V Gurevich

  33. The structural basis of the arrestin binding to GPCRs

    Article • Molecular and Cellular Endocrinology, March 2019, Elsevier

    Dr Vsevolod V Gurevich

  34. Arrestins and G proteins in cellular signaling: The coin has two sides

    Article • Science Signaling, September 2018, American Association for the Advancement of Science

    Dr Vsevolod V Gurevich

  35. Arrestins: structural disorder creates rich functionality

    Article • Protein & Cell, February 2018, Oxford University Press (OUP)

    Dr Vsevolod V Gurevich

  36. Heterologous phosphorylation-induced formation of a stability lock permits regulation of inactive receptors by β-arrestins

    Article • Journal of Biological Chemistry, November 2017, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  37. Structural basis of arrestin-3 activation and signaling

    Article • Nature Communications, November 2017, Springer Science + Business Media

    Dr Vsevolod V Gurevich

  38. Differential manipulation of arrestin-3 binding to basal and agonist-activated G protein-coupled receptors

    Article • Cellular Signalling, August 2017, Elsevier

    Dr Vsevolod V Gurevich

  39. Quantitative Signaling and Structure-Activity Analyses Demonstrate Functional Selectivity at the Nociceptin/Orphanin FQ Opioid Receptor

    Article • Molecular Pharmacology, September 2015, Elsevier

    Dr Vsevolod V Gurevich

  40. Beyond traditional pharmacology: new tools and approaches

    Article • Bone Marrow Transplantation, June 2015, Wiley

    Dr Vsevolod V Gurevich

  41. GRK3 suppresses L-DOPA-induced dyskinesia in the rat model of Parkinson’s disease via its RGS homology domain

    Article • Scientific Reports, June 2015, Nature

    Dr Vsevolod V Gurevich

  42. How genetic errors in GPCRs affect their function: Possible therapeutic strategies

    Article • Genes & Diseases, June 2015, Tsinghua University Press

    Dr Vsevolod V Gurevich

  43. C-terminal threonines and serines play distinct roles in the desensitization of rhodopsin, a G protein-coupled receptor

    Article • eLife, April 2015, eLife

    Dr Vsevolod V Gurevich

  44. GPCR structure, function, drug discovery and crystallography: report from Academia-Industry International Conference (UK Royal Society) Chicheley Hall, 1–2 September 2014

    Article • Naunyn-Schmiedeberg s Archives of Pharmacology, March 2015, Springer Science + Business Media

    Dr Vsevolod V Gurevich

  45. G Protein-coupled Receptor Kinases of the GRK4 Protein Subfamily Phosphorylate Inactive G Protein-coupled Receptors (GPCRs)

    Article • Journal of Biological Chemistry, March 2015, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  46. Arrestins

    Article • January 2015, Elsevier

    Dr Vsevolod V Gurevich

  47. The Rhodopsin-Arrestin-1 Interaction in Bicelles

    Article • January 2015, Springer Science + Business Media

    Dr Vsevolod V Gurevich

  48. Arrestins regulate cell spreading and motility via focal adhesion dynamics

    Article • Molecular Biology of the Cell, December 2014, American Society for Cell Biology (ASCB)

    Dr Vsevolod V Gurevich

  49. Arrestin Expression inE. coliand Purification

    Article • December 2014, Wiley

    Dr Vsevolod V Gurevich

  50. Overview of Different Mechanisms of Arrestin-Mediated Signaling

    Article • December 2014, Wiley

    Dr Vsevolod V Gurevich

  51. Imaging visual arrestin in vivo

    Article • The FASEB Journal, October 2014, Federation of American Societies For Experimental Biology (FASEB)

    Professor Bruce Berkowitz, Dr Vsevolod V Gurevich

  52. Peptide Modifications Differentially Alter G Protein-Coupled Receptor Internalization and Signaling Bias

    Article • Angewandte Chemie, July 2014, Wiley

    Dr Vsevolod V Gurevich

  53. Mutations in arrestin-3 differentially affect binding to neuropeptide Y receptor subtypes

    Article • Cellular Signalling, July 2014, Elsevier

    Dr Vsevolod V Gurevich

  54. Identification of Receptor Binding-induced Conformational Changes in Non-visual Arrestins

    Article • Journal of Biological Chemistry, May 2014, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  55. Arrestin-3 binds the MAP kinase JNK3α2 via multiple sites on both domains

    Article • Cellular Signalling, April 2014, Elsevier

    Dr Vsevolod V Gurevich

  56. Extensive shape shifting underlies functional versatility of arrestins

    Article • Current Opinion in Cell Biology, April 2014, Elsevier

    Dr Vsevolod V Gurevich

  57. Arrestin makes T cells stop and become active

    Article • The EMBO Journal, February 2014, Wiley

    Dr Vsevolod V Gurevich

  58. Arrestins - Pharmacology and Therapeutic Potential

    Article • January 2014, Springer Science + Business Media

    Dr Vsevolod V Gurevich

  59. Rapid degeneration of rod photoreceptors expressing self-association-deficient arrestin-1 mutant

    Article • Cellular Signalling, December 2013, Elsevier

    Dr Vsevolod V Gurevich

  60. Arrestin-3 Binds c-Jun N-terminal Kinase 1 (JNK1) and JNK2 and Facilitates the Activation of These Ubiquitous JNK Isoforms in Cells via Scaffolding

    Article • Journal of Biological Chemistry, November 2013, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  61. Arrestins in Apoptosis

    Article • November 2013, Springer Science + Business Media

    Dr Vsevolod V Gurevich

  62. Arrestin-Dependent Activation of JNK Family Kinases

    Article • November 2013, Springer Science + Business Media

    Dr Vsevolod V Gurevich

  63. Enhanced Phosphorylation-Independent Arrestins and Gene Therapy

    Article • November 2013, Springer Science + Business Media

    Dr Vsevolod V Gurevich

  64. Self-Association of Arrestin Family Members

    Article • November 2013, Springer Science + Business Media

    Dr Vsevolod V Gurevich

  65. Targeting Individual GPCRs with Redesigned Nonvisual Arrestins

    Article • November 2013, Springer Science + Business Media

    Dr Vsevolod V Gurevich

  66. Therapeutic Potential of Small Molecules and Engineered Proteins

    Article • November 2013, Springer Science + Business Media

    Dr Vsevolod V Gurevich

  67. Constitutively active rhodopsin mutants causing night blindness are effectively phosphorylated by GRKs but differ in arrestin-1 binding

    Article • Cellular Signalling, November 2013, Elsevier

    Dr Vsevolod V Gurevich

  68. Caspase-cleaved arrestin-2 and BID cooperatively facilitate cytochrome C release and cell death

    Article • Cell Death and Differentiation, October 2013, Nature

    Dr Vsevolod V Gurevich

  69. JNK3 Enzyme Binding to Arrestin-3 Differentially Affects the Recruitment of Upstream Mitogen-activated Protein (MAP) Kinase Kinases

    Article • Journal of Biological Chemistry, August 2013, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  70. Visual arrestin interaction with clathrin adaptor AP-2 regulates photoreceptor survival in the vertebrate retina

    Article • Proceedings of the National Academy of Sciences, May 2013, Proceedings of the National Academy of Sciences

    Dr Vsevolod V Gurevich

  71. Insights into congenital stationary night blindness based on the structure of G90D rhodopsin

    Article • EMBO Reports, April 2013, Wiley

    Dr Vsevolod V Gurevich

  72. Critical Role of the Central 139-Loop in Stability and Binding Selectivity of Arrestin-1

    Article • Journal of Biological Chemistry, March 2013, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  73. Structural Determinants of Arrestin Functions

    Article • January 2013, Elsevier

    Dr Vsevolod V Gurevich

  74. Involvement of distinct arrestin-1 elements in binding to different functional forms of rhodopsin

    Article • Proceedings of the National Academy of Sciences, December 2012, Proceedings of the National Academy of Sciences

    Dr Vsevolod V Gurevich

  75. Engineering Visual Arrestin-1 with Special Functional Characteristics

    Article • Journal of Biological Chemistry, December 2012, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  76. Ligand Directed Signaling Differences between Rodent and Human κ-Opioid Receptors

    Article • Journal of Biological Chemistry, December 2012, Elsevier

    Dr Vsevolod V Gurevich

  77. Identification of phosphorylation sites in the COOH‐terminal tail of the μ‐opioid receptor

    Article • Journal of Neurochemistry, November 2012, Wiley

    Professor Graeme Henderson, Dr Vsevolod V Gurevich

  78. Conformation of receptor-bound visual arrestin

    Article • Proceedings of the National Academy of Sciences, October 2012, Proceedings of the National Academy of Sciences

    Dr Vsevolod V Gurevich

  79. Synthetic biology with surgical precision: Targeted reengineering of signaling proteins

    Article • Cellular Signalling, October 2012, Elsevier

    Dr Vsevolod V Gurevich

  80. Manipulation of Very Few Receptor Discriminator Residues Greatly Enhances Receptor Specificity of Non-visual Arrestins

    Article • Journal of Biological Chemistry, August 2012, Elsevier

    Dr Vsevolod V Gurevich

  81. Silent Scaffolds

    Article • Journal of Biological Chemistry, April 2012, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  82. The Origin and Evolution of G Protein-Coupled Receptor Kinases

    Article • PLOS One, March 2012, PLOS

    Dr Vsevolod V Gurevich

  83. ßarrestin1-biased agonism at human δ-opioid receptor by peptidic and alkaloid ligands

    Article • Cellular Signalling, March 2012, Elsevier

    Dr Vsevolod V Gurevich

  84. Role of Receptor-attached Phosphates in Binding of Visual and Non-visual Arrestins to G Protein-coupled Receptors

    Article • Journal of Biological Chemistry, January 2012, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  85. G protein-coupled receptor kinases: More than just kinases and not only for GPCRs

    Article • Pharmacology & Therapeutics, January 2012, Elsevier

    Dr Vsevolod V Gurevich

  86. The Effect of Arrestin Conformation on the Recruitment of c-Raf1, MEK1, and ERK1/2 Activation

    Article • PLOS One, December 2011, PLOS

    Dr Vsevolod V Gurevich

  87. Nonvisual Arrestins Function as Simple Scaffolds Assembling the MKK4–JNK3α2 Signaling Complex

    Article • Biochemistry, December 2011, American Chemical Society (ACS)

    Dr Vsevolod V Gurevich

  88. The functional cycle of visual arrestins in photoreceptor cells

    Article • Progress in Retinal and Eye Research, November 2011, Elsevier

    Dr Vsevolod V Gurevich

  89. Reduced expression of G protein-coupled receptor kinases in schizophrenia but not in schizoaffective disorder

    Article • Neurobiology of Disease, November 2011, Elsevier

    Dr Vsevolod V Gurevich

  90. A Single Mutation in Arrestin-2 Prevents ERK1/2 Activation by Reducing c-Raf1 Binding

    Article • Biochemistry, August 2011, American Chemical Society (ACS)

    Dr Vsevolod V Gurevich

  91. Progressive Reduction of its Expression in Rods Reveals Two Pools of Arrestin-1 in the Outer Segment with Different Roles in Photoresponse Recovery

    Article • PLOS One, July 2011, PLOS

    Dr Vsevolod V Gurevich

  92. Identification of Arrestin-3-specific Residues Necessary for JNK3 Kinase Activation

    Article • Journal of Biological Chemistry, June 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  93. Ubiquitin Ligase Parkin Promotes Mdm2–Arrestin Interaction but Inhibits Arrestin Ubiquitination

    Article • Biochemistry, May 2011, American Chemical Society (ACS)

    Dr Vsevolod V Gurevich

  94. Identification of key factors that reduce the variability of the single photon response

    Article • Proceedings of the National Academy of Sciences, April 2011, Proceedings of the National Academy of Sciences

    Dr Vsevolod V Gurevich

  95. Few Residues within an Extensive Binding Interface Drive Receptor Interaction and Determine the Specificity of Arrestin Proteins

    Article • Journal of Biological Chemistry, April 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  96. Robust Self-Association Is a Common Feature of Mammalian Visual Arrestin-1

    Article • Biochemistry, March 2011, American Chemical Society (ACS)

    Dr Vsevolod V Gurevich

  97. Crystal Structure of Arrestin-3 Reveals the Basis of the Difference in Receptor Binding Between Two Non-visual Subtypes

    Article • Journal of Molecular Biology, February 2011, Elsevier

    Dr Vsevolod V Gurevich

  98. Arrestin-1 expression level in rods: balancing functional performance and photoreceptor health

    Article • Neuroscience, February 2011, Elsevier

    Dr Vsevolod V Gurevich

  99. Kinetics of Rhodopsin Deactivation and Its Role in Regulating Recovery and Reproducibility of Rod Photoresponse

    Article • PLoS Computational Biology, December 2010, PLOS

    Dr Vsevolod V Gurevich

  100. Elucidation of Inositol Hexaphosphate and Heparin Interaction Sites and Conformational Changes in Arrestin-1 by Solution Nuclear Magnetic Resonance

    Article • Biochemistry, December 2010, American Chemical Society (ACS)

    Dr Vsevolod V Gurevich

  101. Monomeric Rhodopsin Is Sufficient for Normal Rhodopsin Kinase (GRK1) Phosphorylation and Arrestin-1 Binding

    Article • Journal of Biological Chemistry, October 2010, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  102. Ligand-induced Internalization and Recycling of the Human Neuropeptide Y2Receptor Is Regulated by Its Carboxyl-terminal Tail

    Article • Journal of Biological Chemistry, October 2010, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  103. Lentiviral Overexpression of GRK6 Alleviates L-Dopa-Induced Dyskinesia in Experimental Parkinson's Disease

    Article • Science Translational Medicine, April 2010, American Association for the Advancement of Science

    Dr Vsevolod V Gurevich

  104. Custom-designed proteins as novel therapeutic tools? The case of arrestins

    Article • Expert Reviews in Molecular Medicine, April 2010, Cambridge University Press

    Dr Vsevolod V Gurevich

  105. Non-visual Arrestins Are Constitutively Associated with the Centrosome and Regulate Centrosome Function

    Article • Journal of Biological Chemistry, January 2010, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  106. The Role of Arrestin α-Helix I in Receptor Binding

    Article • Journal of Molecular Biology, January 2010, Elsevier

    Dr Vsevolod V Gurevich

  107. Dynamics of mouse rod phototransduction and its sensitivity to variation of key parameters

    Article • IET Systems Biology, January 2010, the Institution of Engineering and Technology (the IET)

    Dr Vsevolod V Gurevich

  108. Enhanced Arrestin Facilitates Recovery and Protects Rods Lacking Rhodopsin Phosphorylation

    Article • Current Biology, May 2009, Elsevier

    Dr Vsevolod V Gurevich

  109. Enhanced Arrestin Facilitates Recovery and Protects Rods Lacking Rhodopsin Phosphorylation

    Article • Current Biology, April 2009, Elsevier

    Dr Vsevolod V Gurevich

  110. Altered Sensitivity to Rewarding and Aversive Drugs in Mice with Inducible Disruption of cAMP Response Element-Binding Protein Function within the Nucleus Accumbens

    Article • Journal of Neuroscience, February 2009, Society for Neuroscience

    Dr Vsevolod V Gurevich

  111. Overexpression of Rhodopsin Alters the Structure and Photoresponse of Rod Photoreceptors

    Article • Biophysical Journal, February 2009, Elsevier

    Dr Vsevolod V Gurevich

  112. How Does Arrestin Assemble MAPKs into a Signaling Complex?

    Article • Journal of Biological Chemistry, November 2008, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  113. An Intracellular Loop 2 Amino Acid Residue Determines Differential Binding of Arrestin to the Dopamine D2 and D3 Receptors

    Article • Molecular Pharmacology, September 2008, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr Vsevolod V Gurevich

  114. A Dopamine D2 Receptor Mutant Capable of G Protein-Mediated Signaling but Deficient in Arrestin Binding

    Article • Molecular Pharmacology, September 2008, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr Vsevolod V Gurevich

  115. Structure and Function of the Third Intracellular Loop of the 5-Hydroxytryptamine2A Receptor: The Third Intracellular Loop Is α-Helical and Binds Purified Arrestins

    Article • Journal of Neurochemistry, June 2008, Wiley

    Dr Vsevolod V Gurevich

  116. A Model for the Solution Structure of the Rod Arrestin Tetramer

    Article • Structure, June 2008, Elsevier

    Dr Vsevolod V Gurevich

  117. Rich Tapestry of G Protein-Coupled Receptor Signaling and Regulatory Mechanisms

    Article • Molecular Pharmacology, May 2008, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr Vsevolod V Gurevich

  118. How and why do GPCRs dimerize?

    Article • Trends in Pharmacological Sciences, May 2008, Elsevier

    Dr Vsevolod V Gurevich

  119. Diffusion of the Second Messengers in the Cytoplasm Acts as a Variability Suppressor of the Single Photon Response in Vertebrate Phototransduction

    Article • Biophysical Journal, May 2008, Elsevier

    Dr Vsevolod V Gurevich

  120. Arrestins and two receptor kinases are upregulated in Parkinson's disease with dementia

    Article • Neurobiology of Aging, March 2008, Elsevier

    Dr Vsevolod V Gurevich

  121. GPCR monomers and oligomers: it takes all kinds

    Article • Trends in Neurosciences, February 2008, Elsevier

    Dr Vsevolod V Gurevich

  122. Haloperidol and Clozapine Differentially Affect the Expression of Arrestins, Receptor Kinases, and Extracellular Signal-Regulated Kinase Activation

    Article • Journal of Pharmacology and Experimental Therapeutics, January 2008, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr Vsevolod V Gurevich

  123. Opposing Effects of Inositol Hexakisphosphate on Rod Arrestin and Arrestin2 Self-Association†

    Article • Biochemistry, January 2008, American Chemical Society (ACS)

    Dr Vsevolod V Gurevich

  124. Altered expression and subcellular distribution of GRK subtypes in the dopamine-depleted rat basal ganglia is not normalized by l-DOPA treatment

    Article • Journal of Neurochemistry, November 2007, Wiley

    Dr Vsevolod V Gurevich

  125. Cone arrestin binding to JNK3 and Mdm2: conformational preference and localization of interaction sites

    Article • Journal of Neurochemistry, November 2007, Wiley

    Dr Vsevolod V Gurevich

  126. Regulation of Arrestin Binding by Rhodopsin Phosphorylation Level

    Article • Journal of Biological Chemistry, September 2007, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  127. Anesthetic considerations during percutaneous nephrolithotomy

    Article • Journal of Clinical Anesthesia, August 2007, Elsevier

    Dr Vsevolod V Gurevich

  128. Functional Comparisons of Visual Arrestins in Rod Photoreceptors of Transgenic Mice

    Article • Investigative Ophthalmology & Visual Science, May 2007, Association for Research in Vision and Ophthalmology (ARVO)

    Dr Vsevolod V Gurevich

  129. Arrestin Mobilizes Signaling Proteins to the Cytoskeleton and Redirects their Activity

    Article • Journal of Molecular Biology, April 2007, Elsevier

    Dr Vsevolod V Gurevich

  130. Structure and function of the visual arrestin oligomer

    Article • The EMBO Journal, March 2007, Wiley

    Dr Vsevolod V Gurevich

  131. Each rhodopsin molecule binds its own arrestin

    Article • Proceedings of the National Academy of Sciences, February 2007, Proceedings of the National Academy of Sciences

    Dr Vsevolod V Gurevich

  132. Arrestin Binding to Calmodulin: A Direct Interaction Between Two Ubiquitous Signaling Proteins

    Article • Journal of Molecular Biology, December 2006, Elsevier

    Dr Vsevolod V Gurevich

  133. The structural basis of arrestin-mediated regulation of G-protein-coupled receptors

    Article • Pharmacology & Therapeutics, June 2006, Elsevier

    Dr Vsevolod V Gurevich

  134. Visual and Both Non-visual Arrestins in Their “Inactive” Conformation Bind JNK3 and Mdm2 and Relocalize Them from the Nucleus to the Cytoplasm

    Article • Journal of Biological Chemistry, May 2006, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  135. Soluble Mimics of the Cytoplasmic Face of the Human V1-Vascular Vasopressin Receptor Bind Arrestin2 and Calmodulin

    Article • Molecular Pharmacology, March 2006, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr Vsevolod V Gurevich

  136. Differential interaction of spin-labeled arrestin with inactive and active phosphorhodopsin

    Article • Proceedings of the National Academy of Sciences, March 2006, Proceedings of the National Academy of Sciences

    Dr Vsevolod V Gurevich

  137. Visual Arrestin Binding to Microtubules Involves a Distinct Conformational Change

    Article • Journal of Biological Chemistry, February 2006, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  138. Article • Genome Biology, January 2006, Springer Science + Business Media

    Dr Vsevolod V Gurevich

  139. The Differential Engagement of Arrestin Surface Charges by the Various Functional Forms of the Receptor

    Article • Journal of Biological Chemistry, December 2005, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  140. Crystal Structure of Cone Arrestin at 2.3Å: Evolution of Receptor Specificity

    Article • Journal of Molecular Biology, December 2005, Elsevier

    Dr Vsevolod V Gurevich

  141. Conformational Differences Between Arrestin2 and Pre-activated Mutants as Revealed by Hydrogen Exchange Mass Spectrometry

    Article • Journal of Molecular Biology, August 2005, Elsevier

    Dr Vsevolod V Gurevich

  142. Pathogenesis of levodopa-induced dyskinesia: focus on D1 and D3 dopamine receptors

    Article • Parkinsonism & Related Disorders, June 2005, Elsevier

    Dr Vsevolod V Gurevich

  143. Light-Dependent Redistribution of Arrestin in Vertebrate Rods Is an Energy-Independent Process Governed by Protein-Protein Interactions

    Article • Neuron, May 2005, Elsevier

    Dr Vsevolod V Gurevich

  144. Dopamine D1 receptor interaction with arrestin3 in neostriatal neurons

    Article • Journal of Neurochemistry, April 2005, Wiley

    Dr Vsevolod V Gurevich

  145. Calmodulin kinase II inhibition protects against structural heart disease

    Article • Nature Medicine, March 2005, Springer Science + Business Media

    Dr Tatiana A Vishnivetskaya, Dr Vsevolod V Gurevich

  146. l-DOPA reverses the MPTP-induced elevation of the arrestin2 and GRK6 expression and enhanced ERK activation in monkey brain

    Article • Neurobiology of Disease, March 2005, Elsevier

    Dr Vsevolod V Gurevich

  147. Arrestin2 expression selectively increases during neural differentiation

    Article • Journal of Neurochemistry, December 2004, Wiley

    Dr Vsevolod V Gurevich

  148. Inhibition of Chemoattractant N-Formyl Peptide Receptor Trafficking by Active Arrestins

    Article • Traffic, November 2004, Wiley

    Dr Vsevolod V Gurevich

  149. Preferential Interaction between the Dopamine D2 Receptor and Arrestin2 in Neostriatal Neurons

    Article • Molecular Pharmacology, September 2004, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr Vsevolod V Gurevich

  150. Direct Binding of Visual Arrestin to Microtubules Determines the Differential Subcellular Localization of Its Splice Variants in Rod Photoreceptors

    Article • Journal of Biological Chemistry, July 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  151. The molecular acrobatics of arrestin activation

    Article • Trends in Pharmacological Sciences, February 2004, Elsevier

    Dr Vsevolod V Gurevich

  152. Mapping the Arrestin-Receptor Interface

    Article • Journal of Biological Chemistry, October 2003, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  153. The New Face of Active Receptor Bound Arrestin Attracts New Partners

    Article • Structure, September 2003, Elsevier

    Dr Vsevolod V Gurevich

  154. Functional Capabilities of anN-Formyl Peptide Receptor−Gαi2Fusion Protein:  Assemblies with G Proteins and Arrestins†

    Article • Biochemistry, June 2003, American Chemical Society (ACS)

    Dr Vsevolod V Gurevich

  155. The Interaction of a Constitutively Active Arrestin with the Arrestin-Insensitive 5-HT2A Receptor Induces Agonist-Independent Internalization

    Article • Molecular Pharmacology, May 2003, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr Vsevolod V Gurevich

  156. The interaction with the cytoplasmic loops of rhodopsin plays a crucial role in arrestin activation and binding

    Article • Journal of Neurochemistry, February 2003, Wiley

    Dr Vsevolod V Gurevich

  157. The Nature of the Arrestin·Receptor Complex Determines the Ultimate Fate of the Internalized Receptor

    Article • Journal of Biological Chemistry, January 2003, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  158. Article • Chemical and Petroleum Engineering, January 2003, Springer Science + Business Media

    Dr Vsevolod V Gurevich

  159. N -Formyl Peptide Receptor Phosphorylation Domains Differentially Regulate Arrestin and Agonist Affinity

    Article • Journal of Biological Chemistry, November 2002, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  160. Transition of Arrestin into the Active Receptor-binding State Requires an Extended Interdomain Hinge

    Article • Journal of Biological Chemistry, September 2002, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  161. The Third Intracellular Loop of α2-Adrenergic Receptors Determines Subtype Specificity of Arrestin Interaction

    Article • Journal of Biological Chemistry, August 2002, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  162. ARF6: a newly appreciated player in G protein-coupled receptor desensitization

    Article • FEBS Letters, May 2002, Wiley

    Dr Vsevolod V Gurevich

  163. Aspartic Acid 564 in the Third Cytoplasmic Loop of the Luteinizing Hormone/Choriogonadotropin Receptor Is Crucial for Phosphorylation-independent Interaction with Arrestin2

    Article • Journal of Biological Chemistry, February 2002, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  164. μ-Opioid Receptors Desensitize Less Rapidly than δ-Opioid Receptors Due to Less Efficient Activation of Arrestin

    Article • Journal of Biological Chemistry, February 2002, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  165. Arrestin2 and arrestin3 are differentially expressed in the rat brain during postnatal development

    Article • Neuroscience, February 2002, Elsevier

    Dr Vsevolod V Gurevich

  166. Conservation of the Phosphate-sensitive Elements in the Arrestin Family of Proteins

    Article • Journal of Biological Chemistry, January 2002, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  167. Arrestin Variants Display Differential Binding Characteristics for the PhosphorylatedN-Formyl Peptide Receptor Carboxyl Terminus

    Article • Journal of Biological Chemistry, January 2002, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  168. Partial Phosphorylation of theN-Formyl Peptide Receptor Inhibits G Protein Association Independent of Arrestin Binding

    Article • Journal of Biological Chemistry, October 2001, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  169. Regulation of Formyl Peptide Receptor Agonist Affinity by Reconstitution with Arrestins and Heterotrimeric G Proteins

    Article • Journal of Biological Chemistry, October 2001, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  170. Crystal Structure of β-Arrestin at 1.9 Å

    Article • Structure, September 2001, Elsevier

    Dr Vsevolod V Gurevich

  171. Real-time Analysis of G Protein-coupled Receptor Reconstitution in a Solubilized System

    Article • Journal of Biological Chemistry, April 2001, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  172. Threonine 180 Is Required for G-protein-coupled Receptor Kinase 3- and β-Arrestin 2-mediated Desensitization of the μ-Opioid Receptor inXenopusOocytes

    Article • Journal of Biological Chemistry, November 2000, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  173. An Additional Phosphate-binding Element in Arrestin Molecule

    Article • Journal of Biological Chemistry, October 2000, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  174. Conserved Phosphoprotein Interaction Motif Is Functionally Interchangeable between Ataxin-7 and Arrestins †

    Article • Biochemistry, June 2000, American Chemical Society (ACS)

    Dr Vsevolod V Gurevich

  175. The ADP ribosylation factor nucleotide exchange factor ARNO promotes β-arrestin release necessary for luteinizing hormone/choriogonadotropin receptor desensitization

    Article • Proceedings of the National Academy of Sciences, May 2000, Proceedings of the National Academy of Sciences

    Dr Vsevolod V Gurevich

  176. Arrestin Binding to the M2Muscarinic Acetylcholine Receptor Is Precluded by an Inhibitory Element in the Third Intracellular Loop of the Receptor

    Article • Journal of Biological Chemistry, March 2000, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  177. Visual Arrestin Activity May Be Regulated by Self-association

    Article • Journal of Biological Chemistry, July 1999, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  178. β-Arrestin-dependent Desensitization of Luteinizing Hormone/Choriogonadotropin Receptor Is Prevented by a Synthetic Peptide Corresponding to the Third Intracellular Loop of the Receptor

    Article • Journal of Biological Chemistry, May 1999, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  179. How Does Arrestin Respond to the Phosphorylated State of Rhodopsin?

    Article • Journal of Biological Chemistry, April 1999, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  180. A Model for Arrestin’s Regulation: The 2.8 Å Crystal Structure of Visual Arrestin

    Article • Cell, April 1999, Elsevier

    Dr Vsevolod V Gurevich

  181. Targeted Construction of Phosphorylation-independent β-Arrestin Mutants with Constitutive Activity in Cells

    Article • Journal of Biological Chemistry, March 1999, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  182. A direct role for arrestins in desensitization of the luteinizing hormone/choriogonadotropin receptor in porcine ovarian follicular membranes

    Article • Proceedings of the National Academy of Sciences, January 1999, Proceedings of the National Academy of Sciences

    Dr Vsevolod V Gurevich

  183. Molecular events associated with the regulation of signaling by M2 muscarinic receptors

    Article • Life Sciences, January 1999, Elsevier

    Dr Vsevolod V Gurevich

  184. The Selectivity of Visual Arrestin for Light-activated Phosphorhodopsin Is Controlled by Multiple Nonredundant Mechanisms

    Article • Journal of Biological Chemistry, June 1998, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  185. Agonist-Receptor-Arrestin, an Alternative Ternary Complex with High Agonist Affinity

    Article • Journal of Biological Chemistry, November 1997, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  186. Internalization of the m2 Muscarinic Acetylcholine Receptor

    Article • Journal of Biological Chemistry, September 1997, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  187. Mechanism of Quenching of Phototransduction

    Article • Journal of Biological Chemistry, July 1997, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  188. Arrestin/Clathrin Interaction

    Article • Journal of Biological Chemistry, June 1997, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  189. Arrestin with a Single Amino Acid Substitution Quenches Light-Activated Rhodopsin in a Phosphorylation-Independent Fashion†

    Article • Biochemistry, June 1997, American Chemical Society (ACS)

    Dr Vsevolod V Gurevich

  190. Role of Arrestins in G-Protein-Coupled Receptor Endocytosis

    Article • January 1997, Elsevier

    Dr Vsevolod V Gurevich

  191. β-Arrestin acts as a clathrin adaptor in endocytosis of the β2-adrenergic receptor

    Article • Nature, October 1996, Nature

    Dr Vsevolod V Gurevich

  192. [21] Use of bacteriophage RNA polymerase in RNA synthesis

    Article • January 1996, Elsevier

    Dr Vsevolod V Gurevich

  193. Visual Arrestin Binding to Rhodopsin

    Article • Journal of Biological Chemistry, March 1995, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vsevolod V Gurevich

  194. In Vitro Transcription: Preparative RNA Yields in Analytical Scale Reactions

    Article • Analytical Biochemistry, August 1994, Elsevier

    Dr Vsevolod V Gurevich

  195. Preparative in vitro mRNA synthesis using SP6 and T7 RNA polymerases

    Article • Analytical Biochemistry, June 1991, Elsevier

    Dr Vsevolod V Gurevich

  196. Functional expression in vitro of bovine visual rhodopsin

    Article • Protein Engineering Design and Selection, January 1990, Oxford University Press (OUP)

    Dr Vsevolod V Gurevich

  197. In vitro synthesis of visual rhodopsin for a protein engineering study

    Article • The Protein Journal, June 1989, Springer Science + Business Media

    Dr Vsevolod V Gurevich