Contact

All Stories

  1. Novel processes to obtain pneumococcal surface proteins for vaccines

    Article • Applied Microbiology and Biotechnology, April 2025, Springer Science + Business Media

    Dr. Viviane Maimoni Goncalves

  2. Optimization of methods for isolation and purification of outer membrane vesicles (OMVs) from Neisseria lactamica

    Article • Applied Microbiology and Biotechnology, April 2025, Springer Science + Business Media

    Dr. Viviane Maimoni Goncalves

  3. In-silico and experimental analysis of Klebsiella pneumoniae fimbriae subunits for vaccine development

    Article • Vaccine, April 2025, Elsevier

    Dr. Viviane Maimoni Goncalves

  4. In-Silico and in Vivo Tools to Select Vaccine Candidates Against Klebsiella Pneumoniae Infection from its Fimbrial Components

    Article • January 2025, Elsevier

    Dr. Viviane Maimoni Goncalves

  5. Comparison Between Simple Batch and Fed-Batch Bioreactor Cultivation of Recombinant BCG

    Article • Pharmaceutics, November 2024, MDPI AG

    Dr. Viviane Maimoni Goncalves

  6. The Toxin of VapBC-1 Toxin-Antitoxin Module from Leptospira interrogans Is a Ribonuclease That Does Not Arrest Bacterial Growth but Affects Cell Viability

    Article • Microorganisms, August 2024, MDPI AG

    Dr. Viviane Maimoni Goncalves

  7. Novel method for production and purification of untagged pneumococcal surface protein A from clade 1

    Article • Applied Microbiology and Biotechnology, April 2024, Springer Science + Business Media

    Dr. Viviane Maimoni Goncalves

  8. Liposome-based dry powder vaccine immunization targeting the lungs induces broad protection against pneumococcus

    Article • Journal of Controlled Release, April 2024, Elsevier

    Dr. Viviane Maimoni Goncalves

  9. Influence of the mRNA initial region on protein production: a case study using recombinant detoxified pneumolysin as a model

    Article • Frontiers in Bioengineering and Biotechnology, January 2024, Frontiers

    Dr. Viviane Maimoni Goncalves

  10. A comprehensive method for modeling and simulating ion exchange chromatography of complex mixtures

    Article • Protein Expression and Purification, May 2023, Elsevier

    Dr. Viviane Maimoni Goncalves

  11. Peptide linker increased the stability of pneumococcal fusion protein vaccine candidate

    Article • Frontiers in Bioengineering and Biotechnology, January 2023, Frontiers

    Dr. Viviane Maimoni Goncalves

  12. Pneumococcal Surface Protein A-Hybrid Nanoparticles Protect Mice from Lethal Challenge after Mucosal Immunization Targeting the Lungs

    Article • Pharmaceutics, June 2022, MDPI AG

    Dr. Viviane Maimoni Goncalves

  13. ClearColi as a platform for untagged pneumococcal surface protein A production: cultivation strategy, bioreactor culture, and purification

    Article • Applied Microbiology and Biotechnology, January 2022, Springer Science + Business Media

    Dr. Viviane Maimoni Goncalves

  14. Robust Immune Response Induced by Schistosoma mansoni TSP-2 Antigen Coupled to Bacterial Outer Membrane Vesicles

    Article • International Journal of Nanomedicine, October 2021, Taylor & Francis

    Dr. Viviane Maimoni Goncalves

  15. Optimization of Expression and Purification of Schistosoma mansoni Antigens in Fusion with Rhizavidin

    Article • Molecular Biotechnology, June 2021, Springer Science + Business Media

    Dr. Viviane Maimoni Goncalves

  16. Strategies for the Production of Soluble Interferon-Alpha Consensus and Potential Application in Arboviruses and SARS-CoV-2

    Article • Life, May 2021, MDPI AG

    Dr. Viviane Maimoni Goncalves

  17. High stabilization and hyperactivation of a Recombinant β-Xylosidase through Immobilization Strategies

    Article • Enzyme and Microbial Technology, April 2021, Elsevier

    Dr. Viviane Maimoni Goncalves

  18. Evaluation of polymer choice on immunogenicity of chitosan coated PLGA NPs with surface-adsorbed pneumococcal protein antigen PspA4Pro

    Article • International Journal of Pharmaceutics, April 2021, Elsevier

    Dr. Viviane Maimoni Goncalves

  19. Development of recombinant human granulocyte colony-stimulating factor (nartograstim) production process in Escherichia coli compatible with industrial scale and with no antibiotics in the culture medium

    Article • Applied Microbiology and Biotechnology, November 2020, Springer Science + Business Media

    Dr. Viviane Maimoni Goncalves

  20. Anti-Flavivirus Vaccines: Review of the Present Situation and Perspectives of Subunit Vaccines Produced in Escherichia coli

    Article • Vaccines, August 2020, MDPI AG

    Dr. Viviane Maimoni Goncalves

  21. Cost analysis based on bioreactor cultivation conditions: Production of a soluble recombinant protein using Escherichia coli BL21(DE3)

    Article • Biotechnology Reports, June 2020, Elsevier

    Dr. Viviane Maimoni Goncalves

  22. Improvement of the production process for a new vaccine against pneumococcal diseases

    Article • Biotechnology and Bioengineering, March 2020, Wiley

    Dr. Viviane Maimoni Goncalves

  23. Modeling and simulation of anion exchange chromatography for purification of proteins in complex mixtures

    Article • Journal of Chromatography A, February 2020, Elsevier

    Dr. Viviane Maimoni Goncalves

  24. Optimization and scale-up production of Zika virus ΔNS1 in Escherichia coli: application of Response Surface Methodology

    Article • AMB Express, December 2019, Springer Science + Business Media

    Dr. Viviane Maimoni Goncalves

  25. Progress in mucosal immunization for protection against pneumococcal pneumonia

    Article • Expert Review of Vaccines, July 2019, Taylor & Francis

    Dr Imran Saleem, Dr. Viviane Maimoni Goncalves

  26. Children as curators: how to incorporate young visitors’ voices into the elaboration and evaluation of a microbiology exhibition

    Article • História Ciências Saúde-Manguinhos, March 2019, FapUNIFESP (SciELO)

    Dr. Viviane Maimoni Goncalves

  27. A new vector for heterologous gene expression in Escherichia coli with increased stability in the absence of antibiotic

    Article • Plasmid, June 2018, Elsevier

    Dr. Viviane Maimoni Goncalves

  28. Learning about Microorganisms in Childhood: Four- to Six-Year-Old Children’s Voice in Kindergartens and Museums

    Article • Revista Brasileira de Pesquisa em Educação em Ciências, April 2018, Revista Brasileira de Pesquisa em Educacao em Ciencia

    Dr. Viviane Maimoni Goncalves

  29. Mucosal immunization with PspA (Pneumococcal surface protein A)-adsorbed nanoparticles targeting the lungs for protection against pneumococcal infection

    Article • PLOS One, January 2018, PLOS

    Dr. Viviane Maimoni Goncalves

  30. Conjugation of PspA4Pro with Capsular Streptococcus pneumoniae Polysaccharide Serotype 14 Does Not Reduce the Induction of Cross-Reactive Antibodies

    Article • Clinical and Vaccine Immunology, June 2017, ASM Journals

    Dr. Viviane Maimoni Goncalves

  31. IL-17A and complement contribute to killing of pneumococci following immunization with a pneumococcal whole cell vaccine

    Article • Vaccine, March 2017, Elsevier

    Dr. Viviane Maimoni Goncalves

  32. Production and purification of an untagged recombinant pneumococcal surface protein A (PspA4Pro) with high-purity and low endotoxin content

    Article • Applied Microbiology and Biotechnology, November 2016, Springer Science + Business Media

    Dr. Viviane Maimoni Goncalves

  33. DEVELOPMENT OF A NEW PROCESS FOR PURIFICATION OF CAPSULAR POLYSACCHARIDE FROM Streptococcus pneumoniae SEROTYPE 14

    Article • Brazilian Journal of Chemical Engineering, September 2016, FapUNIFESP (SciELO)

    Dr. Viviane Maimoni Goncalves

  34. Recombinant protein production by engineered Escherichia coli in a pressurized airlift bioreactor: A techno-economic analysis

    Article • Chemical Engineering and Processing - Process Intensification, May 2016, Elsevier

    Dr. Viviane Maimoni Goncalves, Prof. Alberto Colli Badino

  35. ON-LINE MONITORING OF BIOMASS CONCENTRATION BASED ON A CAPACITANCE SENSOR: ASSESSING THE METHODOLOGY FOR DIFFERENT BACTERIA AND YEAST HIGH CELL DENSITY FED-BATCH CULTURES

    Article • Brazilian Journal of Chemical Engineering, December 2015, FapUNIFESP (SciELO)

    Dr. Viviane Maimoni Goncalves

  36. Pulmonary dry powder vaccine of pneumococcal antigen loaded nanoparticles

    Article • International Journal of Pharmaceutics, November 2015, Elsevier

    Dr. Viviane Maimoni Goncalves

  37. Capsular polysaccharide production by Streptococcus pneumoniae serotype 1: from strain selection to fed-batch cultivation

    Article • Applied Microbiology and Biotechnology, August 2015, Springer Science + Business Media

    Dr. Viviane Maimoni Goncalves

  38. PRODUÇÃO DE UMA MOLÉCULA RECOMBINANTE HÍBRIDA DE DUAS PROTEÍNAS DE Streptococcus pneumoniae: PspA94-PdT

    Article • February 2015, Editora Edgard Blucher, Ltda.

    Dr. Viviane Maimoni Goncalves

  39. Improved capsular polysaccharide production by Streptococcus pneumoniae serotype 14 using continuous cultivation

    Article • Biochemical Engineering Journal, October 2014, Elsevier

    Dr. Viviane Maimoni Goncalves

  40. A supervision and control tool based on artificial intelligence for high cell density cultivations

    Article • Brazilian Journal of Chemical Engineering, June 2014, FapUNIFESP (SciELO)

    Dr. Viviane Maimoni Goncalves

  41. Development of a whole cell pneumococcal vaccine: BPL inactivation, cGMP production, and stability

    Article • Vaccine, February 2014, Elsevier

    Dr. Viviane Maimoni Goncalves

  42. On-line prediction of the feeding phase in high-cell density cultivation of rE. coli using constructive neural networks

    Article • Computer Methods and Programs in Biomedicine, July 2013, Elsevier

    Dr. Viviane Maimoni Goncalves

  43. Conjugation of Polysaccharide 6B from Streptococcus pneumoniae with Pneumococcal Surface Protein A: PspA Conformation and Its Effect on the Immune Response

    Article • Clinical and Vaccine Immunology, April 2013, ASM Journals

    Dr. Viviane Maimoni Goncalves

  44. High cell density co-culture for production of recombinant hydrolases

    Article • Biochemical Engineering Journal, February 2013, Elsevier

    Dr. Viviane Maimoni Goncalves

  45. Intensification of high cell-density cultivations of rE. coli for production of S. pneumoniae antigenic surface protein, PspA3, using model-based adaptive control

    Article • Bioprocess and Biosystems Engineering, March 2012, Springer Science + Business Media

    Dr. Viviane Maimoni Goncalves

  46. Quantification of capsular polysaccharide of Streptococcus pneumoniae serotype 14 in culture broth samples

    Article • Analytical Biochemistry, February 2012, Elsevier

    Dr. Viviane Maimoni Goncalves

  47. Development of production and purification processes of recombinant fragment of pneumococcal surface protein A in Escherichia coli using different carbon sources and chromatography sequences

    Article • Applied Microbiology and Biotechnology, November 2011, Springer Science + Business Media

    Dr. Viviane Maimoni Goncalves

  48. Humoral immune response of a pneumococcal conjugate vaccine: Capsular polysaccharide serotype 14—Lysine modified PspA

    Article • Vaccine, November 2011, Elsevier

    Dr. Viviane Maimoni Goncalves

  49. Robust artificial intelligence tool for automatic start-up of the supplementary medium feeding in recombinant E. coli cultivations

    Article • Bioprocess and Biosystems Engineering, April 2011, Springer Science + Business Media

    Dr. Viviane Maimoni Goncalves

  50. Production and purification of recombinant fragment of pneumococcal surface protein A (PspA) in Escherichia coli

    Article • Procedia in Vaccinology, January 2011, Elsevier

    Dr. Viviane Maimoni Goncalves

  51. GMP-grade pneumococcal whole-cell vaccine injected subcutaneously protects mice from nasopharyngeal colonization and fatal aspiration-sepsis

    Article • Vaccine, November 2010, Elsevier

    Dr. Viviane Maimoni Goncalves

  52. Pneumococcal whole-cell vaccine: optimization of cell growth of unencapsulated Streptococcus pneumoniae in bioreactor using animal-free medium

    Article • Journal of Industrial Microbiology & Biotechnology, August 2008, Springer Science + Business Media

    Dr. Viviane Maimoni Goncalves

  53. Protection induced by pneumococcal surface protein A (PspA) is enhanced by conjugation to a Streptococcus pneumoniae capsular polysaccharide

    Article • Vaccine, June 2008, Elsevier

    Dr. Viviane Maimoni Goncalves

  54. A Heuristic Search for Optimal Parameter Values of Three Biokinetic Growth Models for Describing Batch Cultivations of Streptococcus Pneumoniae in Bioreactors

    Article • January 2008, Springer Science + Business Media

    Dr. Viviane Maimoni Goncalves

  55. An Empirical Investigation of the Use of a Neural Network Committee for Identifying the Streptococcus Pneumoniae Growth Phases in Batch Cultivations

    Article • January 2008, Springer Science + Business Media

    Dr. Viviane Maimoni Goncalves

  56. Strategies for production of polysaccharide for pneumococcal conjugate vaccine

    Article • Journal of Applied Microbiology, November 2006, Wiley

    Dr. Viviane Maimoni Goncalves

  57. Accumulation of organic acids in cultivations of Neisseria meningitidis C

    Article • Journal of Industrial Microbiology & Biotechnology, May 2006, Springer Science + Business Media

    Dr. Viviane Maimoni Goncalves

  58. Industrial purification method of the polysaccharide to be used as vaccine

    Article • Biotechnology and Applied Biochemistry, June 2003, Wiley

    Dr. Viviane Maimoni Goncalves

  59. Optimization of medium and cultivation conditions for capsular polysaccharide production by Streptococcus pneumoniae serotype 23F

    Article • Applied Microbiology and Biotechnology, August 2002, Springer Science + Business Media

    Dr. Viviane Maimoni Goncalves

  60. An associated process for the purification of immuno globulin G, catalase, superoxide dismutase and albumin from haemolysed human placenta blood

    Article • Biotechnology and Applied Biochemistry, December 2001, Wiley

    Dr. Viviane Maimoni Goncalves

  61. Albumin purification from human placenta

    Article • Biotechnology and Applied Biochemistry, April 2000, Wiley

    Dr. Viviane Maimoni Goncalves

  62. Crystallization and preliminary X-ray diffraction studies of human catalase

    Article • Acta Crystallographica Section D Biological Crystallography, September 1999, International Union of Crystallography

    Dr Ronaldo Alves Pinto Nagem, Dr. Viviane Maimoni Goncalves