All Stories

  1. Immune cell infiltration and inflammatory landscape in primary brain tumours

    Article • Journal of Translational Medicine, May 2024, Springer Science + Business Media

    Dr Vittorio Gentile

  2. Amyloid-β-Induced Transglutaminase 2 Expression and Activities are Modulated by 2-Pentadecyl-2-Oxazoline in Mouse and Human Microglial Cell Lines

    Article • Current Alzheimer Research, April 2023, Bentham Science Publishers

    Dr Vittorio Gentile

  3. 2-pentadecyl-2-oxazoline prevents cognitive and social behaviour impairments in the Amyloid β-induced Alzheimer-like mice model: Bring the α2 adrenergic receptor back into play

    Article • Biomedicine & Pharmacotherapy, December 2022, Elsevier

    Dr Vittorio Gentile, Prof Giacinto Bagetta

  4. Neuronutraceuticals Modulate Lipopolysaccharide- or Amyloid-β 1-42 Peptide-Induced Transglutaminase 2 Overexpression as a Marker of Neuroinflammation in Mouse Microglial Cells

    Article • Applied Sciences, June 2021, MDPI AG

    Dr Vittorio Gentile

  5. Possible roles of transglutaminase-catalyzed reactions in the pathogenesis of human neurodegenerative diseases.

    Article • Translational Clinical Biology, March 2016, Vedic Research International

    Dr Vittorio Gentile

  6. Curcumin (Diferulolylmethane) Reduces Transglutaminase 2 Overexpression Induced by Retinoic Acid in Human Nervous Cell Lines

    Article • NeuroImmunoModulation, January 2016, Karger Publishers

    Dr Vittorio Gentile

  7. Possible roles of transglutaminases in molecular mechanisms responsible for human neurodegenerative diseases

    Article • AIMS Biophysics, January 2016, American Institute of Mathematical Sciences (AIMS)

    Dr Vittorio Gentile

  8. Meet Our Editorial Board Member Dr. Vittorio Gentile

    Article • Recent Patents on CNS Drug Discovery, July 2015, Bentham Science Publishers

    Dr Vittorio Gentile

  9. Possible Role of the Transglutaminase Activity in Molecular Mechanisms Responsible for Human Neurodegenerative Diseases

    Article • International Journal of Neurology Research, January 2015, ACT Publishing Group

    Dr Vittorio Gentile

  10. Possible pathophysiological roles of transglutaminase-catalyzed reactions in the pathogenesis of human neurodegenerative diseases

    Article • AIMS Biophysics, January 2015, American Institute of Mathematical Sciences (AIMS)

    Dr Vittorio Gentile

  11. Transglutaminases and neurodegeneration

    Article • Recent Patents on CNS Drug Discovery, December 2014, Bentham Science Publishers

    Dr Vittorio Gentile

  12. Transglutaminases and neurodegeneration

    Article • Recent Patents on CNS Drug Discovery, December 2014, Bentham Science Publishers

    Dr Vittorio Gentile

  13. Transglutaminases and neurodegeneration

    Article • Recent Patents on CNS Drug Discovery, January 2014, Bentham Science Publishers

    Dr Vittorio Gentile

  14. Transglutaminase Inhibition as a Possible Therapeutical Approach to Protect Cells from Death in Neurodegenerative Diseases

    Article • Recent Patents on CNS Drug Discovery, June 2013, Bentham Science Publishers

    Dr Vittorio Gentile

  15. Pathophysiological Roles of Transglutaminase - Catalyzed Reactions in the Pathogenesis of Human Diseases

    Article • Inflammation & Allergy - Drug Targets, June 2012, Bentham Science Publishers

    Dr Vittorio Gentile

  16. Physiopathological Roles of Human Transglutaminase 2

    Article • October 2011, Wiley

    Dr Vittorio Gentile

  17. Possible involvement of transglutaminase-catalyzed reactions in the physiopathology of neurodegenerative diseases

    Article • Amino Acids, September 2011, Springer Science + Business Media

    Dr Vittorio Gentile

  18. Possible Role of the Transglutaminases in the Pathogenesis of Alzheimer's Disease and Other Neurodegenerative Diseases

    Article • International Journal of Alzheimer s Disease, January 2011, Hindawi Publishing Corporation

    Dr Vittorio Gentile

  19. Transglutaminases as Possible Therapeutic Targets in Neurodegenerative Diseases

    Article • Recent Patents on CNS Drug Discovery, November 2010, Bentham Science Publishers

    Dr Vittorio Gentile

  20. Role of the Transglutaminase Enzymes in the Nervous System and their Possible Involvement in Neurodegenerative Diseases

    Article • Current Medicinal Chemistry, December 2009, Bentham Science Publishers

    Dr Vittorio Gentile

  21. Transglutaminase covalently incorporates amines into human immunodeficiency virus envelope glycoprotein GP120 in vitro

    Article • International journal of peptide & protein research, January 2009, Wiley

    Dr Vittorio Gentile

  22. Transglutaminase-catalyzed modifications of SV-IV, a major protein secreted from the rat seminal vesicle epithelium

    Article • International journal of peptide & protein research, January 2009, Wiley

    Dr Vittorio Gentile

  23. Transglutaminase-Catalyzed Post-Translational Modifications of Proteins in the Nervous System and their Possible Involvement in Neurodegenerative Diseases

    Article • CNS & Neurological Disorders - Drug Targets, October 2008, Bentham Science Publishers

    Dr Vittorio Gentile

  24. Pathogenesis of Inclusion Bodies in (CAG)n/Qn-Expansion Diseases with Special Reference to the Role of Tissue Transglutaminase and to Selective Vulnerability

    Article • Journal of Neurochemistry, July 2008, Wiley

    Dr Vittorio Gentile

  25. Role of Transglutaminase-Catalyzed Reactions in the Post-Translational Modifications of Proteins Responsible for Immunological Disorders

    Article • Inflammation & Allergy - Drug Targets, March 2008, Bentham Science Publishers

    Dr Vittorio Gentile

  26. Transglutaminase-Catalyzed Reactions Responsible for the Pathogenesis ofCeliac Disease and Neurodegenerative Diseases: From Basic Biochemistry to Clinic

    Article • Current Medicinal Chemistry, July 2006, Bentham Science Publishers

    Dr Vittorio Gentile

  27. Molecular mechanisms responsible for the involvement of tissue transglutaminase in human diseases: celiac disease

    Article • Frontiers in Bioscience, January 2006, Frontiers in Bioscience

    Dr Vittorio Gentile

  28. Biochemical mechanisms for a possible involvement of the transglutaminase activity in the pathogenesis of the polyglutamine diseases: Minireview article

    Article • Amino Acids, April 2004, Springer Science + Business Media

    Dr Vittorio Gentile

  29. Transglutaminases - Possible Drug Targets in Human Diseases

    Article • Current Drug Targets - CNS & Neurological Disorders, April 2004, Bentham Science Publishers

    Dr Vittorio Gentile

  30. Abnormal Accumulation of tTGase Products in Muscle and Erythrocytes of Chorea-Acanthocytosis Patients

    Article • Journal of Neuropathology & Experimental Neurology, October 2002, Oxford University Press (OUP)

    Dr Vittorio Gentile

  31. Tissue transglutaminase and coeliac disease pathogenesis: potential molecular mechanisms for other human diseases

    Article • Neurochemistry International, January 2002, Elsevier

    Dr Vittorio Gentile

  32. Cross linking of polyglutamine domains catalyzed by tissue transglutaminase is greatly favored with pathological-length repeats: does transglutaminase activity play a role in (CAG)n/Qn-expansion diseases?

    Article • Neurochemistry International, January 2002, Elsevier

    Dr Vittorio Gentile

  33. Transglutaminase-dependent formation of protein aggregates as possible biochemical mechanism for polyglutamine diseases

    Article • Brain Research Bulletin, November 2001, Elsevier

    Dr Vittorio Gentile

  34. Changes in Tissue Transglutaminase Activity and Expression during Retinoic Acid-Induced Growth Arrest and Apoptosis in Primary Cultures of Human Epithelial Prostate Cells1

    Article • The Journal of Clinical Endocrinology & Metabolism, April 1999, Endocrine Society

    Dr Vittorio Gentile

  35. TISSUE TRANSGLUTAMINASE EXPRESSION IN QUAIL EPIPHYSEAL CHONDROCYTES

    Article • Cell Biology International, January 1999, Wiley

    Dr Vittorio Gentile

  36. Tissue transglutaminase expression affects hypusine metabolism in BALB/c 3T3 cells

    Article • FEBS Letters, October 1998, Wiley

    Dr Vittorio Gentile

  37. Tissue Transglutaminase-Catalyzed Formation of High-Molecular-Weight Aggregatesin VitroIs Favored with Long Polyglutamine Domains: A Possible Mechanism Contributing to CAG-Triplet Diseases

    Article • Archives of Biochemistry and Biophysics, April 1998, Elsevier

    Dr Vittorio Gentile

  38. Lack of ‘tissue’ transglutaminase protein cross-linking leads to leakage of macromolecules from dying cells: relationship to development of autoimmunity in MRLlpr/lpr mice

    Article • Cell Death and Differentiation, August 1997, Springer Science + Business Media

    Alessandra Amendola, Dr Vittorio Gentile

  39. tTGase/Gαh protein expression inhibits adenylate cyclase activity in Balb-C 3T3 fibroblasts membranes

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, June 1997, Elsevier

    Dr Vittorio Gentile

  40. Cell-biomaterial interactions: role of transglutaminase enzyme

    Article • Journal of Materials Science Materials in Medicine, December 1996, Springer Science + Business Media

    Dr Vittorio Gentile

  41. The importance of the GTP-binding protein tissue transglutaminase in the regulation of cell cycle progression

    Article • FEBS Letters, August 1995, Wiley

    Dr Vittorio Gentile

  42. Localization of the Human Prostate Transglutaminase (Type IV) Gene (TGM4) to Chromosome 3p21.33-p22 by Fluorescence in Situ Hybridization

    Article • Genomics, May 1995, Elsevier

    Dr Vittorio Gentile

  43. Isolation and Characterization of the Human Tissue Transglutaminase Gene Promoter

    Article • Journal of Biological Chemistry, April 1995, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vittorio Gentile

  44. Tissue transglutaminase and apoptosis: sense and antisense transfection studies with human neuroblastoma cells.

    Article • Molecular and Cellular Biology, October 1994, ASM Journals

    Dr Vittorio Gentile

  45. The Human Tissue Transglutaminase Gene Maps on Chromosome 20q12 by in Situ Fluorescence Hybridization

    Article • Genomics, March 1994, Elsevier

    Dr Vittorio Gentile

  46. Expression of tissue transglutaminase in Balb-C 3T3 fibroblasts: effects on cellular morphology and adhesion

    Article • Journal of Cell Biology, October 1992, Rockefeller University Press

    Dr Vittorio Gentile

  47. Cereal dietary proteins with sites for cross-linking by transglutaminase

    Article • Phytochemistry, January 1990, Elsevier

    Dr Vittorio Gentile

  48. Spermine binding to subsynaptosomal fractions of rat brain cortex

    Article • Neurochemical Research, April 1988, Springer Science + Business Media

    Dr Vittorio Gentile

  49. B-lipotropin 61–76 and 61–91 fragments act as transglutaminase substrates in vitro

    Article • Neuropeptides, February 1988, Elsevier

    Dr Vittorio Gentile

  50. Implication of Transglutaminase in Mitogen-Induced Human Lymphocyte Blast Transformation

    Article • January 1988, Springer Science + Business Media

    Dr Vittorio Gentile

  51. ARE SOLUBLE AND/OR MEMBRANE-BOUND TRANSGLUTAMINASE ACTIVITIES INVOLVED IN INTESTINAL METABOLISM OF GLIADINS?

    Article • Pediatric Research, August 1987, Nature

    Dr Vittorio Gentile

  52. Factors modulating immunocompatibility of spermatozoa: role of transglutaminase and SV-IV, one of the major proteins secreted from the rat seminal vesicle epithelium

    Article • January 1987, Springer Science + Business Media

    Dr Vittorio Gentile

  53. Transglutaminase-mediated modifications of the rat sperm surface in vitro

    Article • Science, November 1984, American Association for the Advancement of Science

    Dr Vittorio Gentile

  54. Cerebral Polyamine Metabolism: Inhibition of Spermidine Biosynthesis by Dicyclohexylamine

    Article • Journal of Neurochemistry, February 1984, Wiley

    Dr Vittorio Gentile