All Stories

  1. Mitochondrial preservation underlies the antioxidant activity of nanoceria particles in light-induced retinal degeneration

    Article • Nanomedicine Nanotechnology Biology and Medicine, September 2026, Elsevier

    PhD Vincenzo Flati

  2. Oxidative Stress Signaling and Regenerative Responses in a Larval Zebrafish Model of Retinal Light Damage

    Article • Antioxidants, March 2026, MDPI AG

    Dr Luigi Donato, PhD Vincenzo Flati

  3. Oxidative Stress Signaling and Regenerative Responses in a Larval Zebrafish Model of Retinal Light Damage

    Article • February 2026, MDPI AG

    PhD Vincenzo Flati

  4. The tumor suppressor role of mitochondrial E3 ubiquitin ligase MUL1 in osteosarcoma

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, February 2026, Elsevier

    PhD Vincenzo Flati

  5. Editorial: Immuno-metabolic interactions and cancer progression in the tumor microenvironment

    Article • Frontiers in Immunology, January 2026, Frontiers

    PhD Vincenzo Flati

  6. Comprehensive transcriptomic analysis reveals canonical and novel pathways modulated by nanoceria in mammalian retinal degeneration

    Article • Scientific Reports, January 2026, Springer Science + Business Media

    PhD Vincenzo Flati, Dr Luigi Donato

  7. Hormetic Effects of Curcumin in RPE Cells: SIRT1 and Caspase-3 Inactivation with Implications for AMD

    Article • International Journal of Molecular Sciences, September 2025, MDPI AG

    PhD Vincenzo Flati

  8. Pyrroloquinoline Quinone (PQQ) Attenuates Hydrogen Peroxide-Induced Injury Through the Enhancement of Mitochondrial Function in Human Trabecular Meshwork Cells

    Article • International Journal of Molecular Sciences, July 2025, MDPI AG

    PhD Vincenzo Flati

  9. Protective effects of fatty acid amide hydrolase inhibition in UVB-activated microglia

    Article • Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, October 2024, Elsevier

    PhD Vincenzo Flati

  10. The C-terminus of the prototypical M2 muscarinic receptor localizes to the mitochondria and regulates cell respiration under stress conditions

    Article • PLoS Biology, April 2024, PLOS

    PhD Vincenzo Flati

  11. Protein Stability Regulation in Osteosarcoma: The Ubiquitin-like Modifications and Glycosylation as Mediators of Tumor Growth and as Targets for Therapy

    Article • Cells, March 2024, MDPI AG

    PhD Vincenzo Flati

  12. Role of the Mitochondrial E3 Ubiquitin Ligases as Possible Therapeutic Targets in Cancer Therapy

    Article • International Journal of Molecular Sciences, December 2023, MDPI AG

    PhD Vincenzo Flati

  13. Anti-Obesity and Anti-Inflammatory Effects of Novel Carvacrol Derivatives on 3T3-L1 and WJ-MSCs Cells

    Article • Pharmaceuticals, February 2023, MDPI AG

    PhD Vincenzo Flati

  14. New Insights into Dose-Dependent Effects of Curcumin on ARPE-19 Cells

    Article • International Journal of Molecular Sciences, November 2022, MDPI AG

    PhD Vincenzo Flati

  15. mTOR Signaling in BDNF-Treated Guinea Pigs after Ototoxic Deafening

    Article • Biomedicines, November 2022, MDPI AG

    PhD Vincenzo Flati

  16. Mitochondrial and metabolic alterations in cancer cells

    Article • European Journal of Cell Biology, August 2022, Elsevier

    PhD Vincenzo Flati

  17. Antioxidant Properties of Cerium Oxide Nanoparticles Prevent Retinal Neovascular Alterations In Vitro and In Vivo

    Article • Antioxidants, June 2022, MDPI AG

    PhD Vincenzo Flati

  18. Characterization of SARS-CoV-2 Entry Factors' Expression in Corneal and Limbal Tissues of Adult Human Donors Aged from 58 to 85

    Article • Journal of Ocular Pharmacology and Therapeutics, January 2022, Mary Ann Liebert Inc

    PhD Vincenzo Flati

  19. Editorial: The Dynamic Interplay Between Nutrition, Autophagy and Cell Metabolism

    Article • Frontiers in Cell and Developmental Biology, April 2021, Frontiers

    PhD Vincenzo Flati

  20. The C-terminus of the prototypical M2 muscarinic receptor localizes to the mitochondria and regulates cell respiration under stress conditions

    Article • April 2021, openRxiv

    PhD Vincenzo Flati

  21. How Can Malnutrition Affect Autophagy in Chronic Heart Failure? Focus and Perspectives

    Article • International Journal of Molecular Sciences, March 2021, MDPI AG

    PhD Vincenzo Flati

  22. The Epithelial-to-Mesenchymal Transition as a Possible Therapeutic Target in Fibrotic Disorders

    Article • Frontiers in Cell and Developmental Biology, December 2020, Frontiers

    PhD Vincenzo Flati

  23. Nanoceria Particles Are an Eligible Candidate to Prevent Age-Related Macular Degeneration by Inhibiting Retinal Pigment Epithelium Cell Death and Autophagy Alterations

    Article • Cells, July 2020, MDPI AG

    PhD Vincenzo Flati

  24. Up-regulation of pro-angiogenic pathways and induction of neovascularization by an acute retinal light damage

    Article • Scientific Reports, April 2020, Springer Science + Business Media

    PhD Vincenzo Flati

  25. Influence of Diets with Varying Essential/Nonessential Amino Acid Ratios on Mouse Lifespan

    Article • Nutrients, June 2019, MDPI AG

    PhD Vincenzo Flati

  26. A Method to Study the C924T Polymorphism of the Thromboxane A2 Receptor Gene

    Article • Journal of Visualized Experiments, April 2019, MyJove Corporation

    PhD Vincenzo Flati

  27. Tebuconazole and Econazole Act Synergistically in Mediating Mitochondrial Stress, Energy Imbalance, and Sequential Activation of Autophagy and Apoptosis in Mouse Sertoli TM4 Cells: Possible Role of AMPK/ULK1 Axis

    Article • Toxicological Sciences, January 2019, Oxford University Press (OUP)

    PhD Vincenzo Flati

  28. Mammalian Target of Rapamycin: Is It Relevant to COPD Pathogenesis or Treatment?

    Article • COPD Journal of Chronic Obstructive Pulmonary Disease, January 2019, Taylor & Francis

    PhD Vincenzo Flati

  29. Is the Response of Tumours Dependent on the Dietary Input of Some Amino Acids or Ratios among Essential and Non-Essential Amino Acids? All That Glitters Is Not Gold

    Article • International Journal of Molecular Sciences, November 2018, MDPI AG

    PhD Vincenzo Flati

  30. Carvacrol reduces adipogenic differentiation by modulating autophagy and ChREBP expression

    Article • PLOS One, November 2018, PLOS

    PhD Vincenzo Flati

  31. Is the Response of Tumours Dependent on Dietary Input of Some Amino Acids or on the Ratios Among Essential and Non-Essential Amino Acids? All That Glisters is Not Gold

    Article • October 2018, MDPI AG

    PhD Vincenzo Flati

  32. Autophagy processes are dependent on EGF receptor signaling

    Article • Oncotarget, July 2018, Impact Journals, LLC

    PhD Vincenzo Flati

  33. Body Weight Loss and Tissue Wasting in Late Middle-Aged Mice on Slightly Imbalanced Essential/Non-essential Amino Acids Diet

    Article • Frontiers in Medicine, May 2018, Frontiers

    PhD Vincenzo Flati

  34. Body Weight Loss, Tissue Wasting and Shortened Lifespan in Late Middle-aged Mice on Imbalanced Essential/Non-essential Amino Acids Diet

    Article • February 2018, MDPI AG

    PhD Vincenzo Flati

  35. Differential TBXA2 receptor transcript stability is dependent on the C924T polymorphism

    Article • Prostaglandins & Other Lipid Mediators, January 2018, Elsevier

    PhD Vincenzo Flati

  36. Pharmacological treatment with inhibitors of nuclear export enhances the antitumor activity of docetaxel in human prostate cancer

    Article • Oncotarget, November 2017, Impact Journals, LLC

    PhD Vincenzo Flati

  37. Diet enrichment with a specific essential free amino acid mixture improves healing of undressed wounds in aged rats

    Article • Experimental Gerontology, October 2017, Elsevier

    PhD Vincenzo Flati

  38. Essential amino acid mixtures drive cancer cells to apoptosis

    Article • European Journal of Biochemistry, May 2017, Wiley

    PhD Vincenzo Flati

  39. Role of glycogen synthase kinase-3β and PPAR-γ on epithelial-to-mesenchymal transition in DSS-induced colorectal fibrosis

    Article • PLOS One, February 2017, PLOS

    PhD Vincenzo Flati

  40. Aging Skin: Nourishing from the Inside Out – Effects of Good Versus Poor Nitrogen Intake on Skin Health and Healing

    Article • September 2016, Springer Science + Business Media

    PhD Vincenzo Flati

  41. Aging Skin: Nourishing from Out-In – Lessons from Wound Healing

    Article • September 2016, Springer Science + Business Media

    PhD Vincenzo Flati

  42. Variants of G protein-coupled receptors: a reappraisal of their role in receptor regulation

    Article • Biochemical Society Transactions, April 2016, Portland Press Ltd.

    PhD Vincenzo Flati

  43. Amino acids supplementation as a cancer fighting weapon

    Article • Anti-Cancer Agents in Medicinal Chemistry, November 2015, Bentham Science Publishers

    PhD Vincenzo Flati

  44. Retraction: Guanosine Inhibits CD40 Receptor Expression and Function Induced by Cytokines and β Amyloid in Mouse Microglia Cells

    Article • The Journal of Immunology, January 2015, The American Association of Immunologists

    PhD Vincenzo Flati

  45. Aging Skin: Nourishing from Out-In. Lessons from Wound Healing

    Article • January 2015, Springer Science + Business Media

    PhD Vincenzo Flati

  46. Aging Skin: Nourishing from the Inside Out, Effects of Good Versus Poor Nitrogen Intake on Skin Health and Healing

    Article • January 2015, Springer Science + Business Media

    PhD Vincenzo Flati

  47. Protect and Counter-attack: Nutritional Supplementation with Essential Amino acid Ratios Reduces Doxorubicin–induced Cardiotoxicity in vivo and promote Cancer Cell Death in vitro

    Article • Journal of Cytology & Histology, January 2015, OMICS Publishing Group

    PhD Vincenzo Flati

  48. Mechanisms of initiation and progression of intestinal fibrosis in IBD

    Article • Scandinavian Journal of Gastroenterology, December 2014, Taylor & Francis

    PhD Vincenzo Flati

  49. Effect of antihypertensive treatments on insulin signalling in lympho-monocytes of essential hypertensive patients: A pilot study

    Article • Blood Pressure, May 2014, Taylor & Francis

    PhD Vincenzo Flati

  50. P084 Dissecting the role of PPARgamma in intestinal fibrosis: EMT-activator ZEB1 as new molecular target

    Article • Journal of Crohn s and Colitis, February 2014, Oxford University Press (OUP)

    PhD Vincenzo Flati, Laurent Dubuquoy

  51. Effects of treadmill exercise and training frequency on anabolic signaling pathways in the skeletal muscle of aged rats

    Article • Experimental Gerontology, January 2012, Elsevier

    PhD Vincenzo Flati

  52. EFFECT OF SHORT-TERM TREATMENT WITH TELMISARTAN OR NIFEDIPINE ON INSULIN SIGNALLING IN LYMPHOMONOCYTES OF ESSENTIAL HYPERTENSIVE PATIENTS

    Article • Journal of Hypertension, June 2011, Wolters Kluwer Health

    PhD Vincenzo Flati

  53. Intracellular molecular effects of insulin resistance in patients with metabolic syndrome

    Article • Cardiovascular Diabetology, January 2010, Springer Science + Business Media

    PhD Vincenzo Flati

  54. Essential Amino Acids Improve Insulin Activation of Akt/mTOR Signaling in Soleus Muscle of Aged Rats

    Article • International Journal of Immunopathology and Pharmacology, January 2010, SAGE Publications

    PhD Vincenzo Flati

  55. Epigenetic modulation of PTEN expression during antiandrogenic therapies in human prostate cancer

    Article • International Journal of Oncology, September 2009, Spandidos Publications

    PhD Vincenzo Flati

  56. Angiotensin receptor blockers improve insulin signaling and prevent microvascular rarefaction in the skeletal muscle of spontaneously hypertensive rats

    Article • Journal of Hypertension, August 2008, Wolters Kluwer Health

    PhD Vincenzo Flati

  57. Morphometric Changes Induced by Amino Acid Supplementation in Skeletal and Cardiac Muscles of Old Mice

    Article • The American Journal of Cardiology, June 2008, Elsevier

    PhD Vincenzo Flati

  58. Intracellular Mechanisms of Metabolism Regulation: The Role of Signaling via the Mammalian Target of Rapamycin Pathway and Other Routes

    Article • The American Journal of Cardiology, June 2008, Elsevier

    PhD Vincenzo Flati

  59. Oral Amino Acid Supplementation Counteracts Age-Induced Sarcopenia in Elderly Rats

    Article • The American Journal of Cardiology, June 2008, Elsevier

    PhD Vincenzo Flati

  60. Amino Acid Supplementation Counteracts Metabolic and Functional Damage in the Diabetic Rat Heart

    Article • The American Journal of Cardiology, June 2008, Elsevier

    PhD Vincenzo Flati

  61. Guanosine inhibits CD40 receptor expression and function induced by cytokines and   amyloid in mouse microglia cells

    Article • The Journal of Immunology, April 2007, The American Association of Immunologists

    PhD Vincenzo Flati

  62. Guanosine Inhibits CD40 Receptor Expression and Function Induced by Cytokines and   Amyloid in Mouse Microglia Cells

    Article • The Journal of Immunology, January 2007, The American Association of Immunologists

    PhD Vincenzo Flati

  63. Impaired Insulin Signalling in Lympho/Monocytes of Patients with Metabolic Syndrome

    Article • High Blood Pressure & Cardiovascular Prevention, January 2007, Springer Science + Business Media

    PhD Vincenzo Flati

  64. Impaired Insulin Signalling in the Heart and Skeletal Muscle of Spontaneously Hypertensive Rats, and Effects of Treatment with an Angiotensin Receptor Blocker or with an ACE Inhibitor

    Article • High Blood Pressure & Cardiovascular Prevention, January 2007, Springer Science + Business Media

    PhD Vincenzo Flati

  65. Endothelial Cell Anergy is Mediated by bFGF through the Sustained Activation of p38-MAPK and NF-κB Inhibition

    Article • International Journal of Immunopathology and Pharmacology, October 2006, SAGE Publications

    PhD Vincenzo Flati

  66. Genomic Organization and Cytokine-Mediated Inducibility of the Human Trim-8/Gerp Gene

    Article • International Journal of Immunopathology and Pharmacology, May 2004, SAGE Publications

    PhD Vincenzo Flati

  67. New mutations and protein variants ofNBS1 are identified in cancer cell lines

    Article • Genes Chromosomes and Cancer, December 2002, Wiley

    PhD Vincenzo Flati

  68. TRIM8/GERP RING Finger Protein Interacts with SOCS-1

    Article • Journal of Biological Chemistry, August 2002, American Society for Biochemistry & Molecular Biology (ASBMB)

    PhD Vincenzo Flati

  69. The Murine p202 Protein, an IFN-Inducible Modulator of Transcription, Is Activated by the Mitogen Platelet-Derived Growth Factor

    Article • Journal of Interferon & Cytokine Research, February 2001, Mary Ann Liebert Inc

    PhD Vincenzo Flati

  70. Two gamma-interferon-activation sites (GAS) on the promoter of the human intercellular adhesion molecule (ICAM-1) gene are required for induction of transcription by IFN-gamma

    Article • European Journal of Biochemistry, December 1998, Wiley

    PhD Vincenzo Flati

  71. Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF-1 and NF-kappa B

    Article • The EMBO Journal, January 1997, Wiley

    Professor Bryan R. G. Williams, PhD Vincenzo Flati

  72. Interferon-alpha-induced phosphorylation and activation of cytosolic phospholipase A2 is required for the formation of interferon-stimulated gene factor three.

    Article • The EMBO Journal, April 1996, Wiley

    PhD Vincenzo Flati

  73. Involvement of an Arachidonic-Acid-Dependent Pathway in the Interferon-beta-Mediated Expression of C202 Gene in Ehrlich-Ascites-Tumor Cells

    Article • European Journal of Biochemistry, January 1996, Wiley

    PhD Vincenzo Flati

  74. Roles of Protein-tyrosine Phosphatases in Stat1 -mediated Cell Signaling

    Article • Journal of Biological Chemistry, October 1995, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Bryan R. G. Williams, PhD Vincenzo Flati

  75. Enzymatic synthesis of S-aminoethyl-l-cysteine from pantetheine

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, March 1992, Elsevier

    PhD Vincenzo Flati