All Stories

  1. Design-Based Research in Higher Education: Analysing Examples Through Activity Theory and Bakker’s Five Characteristics

    Article • Journal of University Teaching and Learning Practice, June 2026, Office of the Academic Executive Director, University of Tasmania

    Dr Louise Townsin, Vijay Rajagopal

  2. Cardiac myofibril networks induce shear stress

    Article • npj Systems Biology and Applications, April 2026, Springer Science + Business Media

    Vijay Rajagopal

  3. Calcium handling in sheep ventricular cardiomyocytes during aging and pressure overload

    Article • Journal of Molecular and Cellular Cardiology Plus, March 2026, Elsevier

    Vijay Rajagopal

  4. Calcium-dependent regulation of physiological vs pathological cardiomyocyte hypertrophy

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, December 2025, Elsevier

    Vijay Rajagopal

  5. Cardiac myofibril networks induce shear stress

    Article • November 2025, Cold Spring Harbor Laboratory Press

    Vijay Rajagopal

  6. A cross-scale analysis for the determinants of bonding dynamics on the distributions of rolling velocities of cells in microvessels

    Article • Biophysical Journal, November 2025, Elsevier

    Vijay Rajagopal

  7. The Human Cardiac “Age‐OME”: Age‐Specific Changes in Myocardial Molecular Expression

    Article • Aging Cell, September 2025, Wiley

    Vijay Rajagopal

  8. The Molecular Landscape of the Ageing Human Heart

    Article • Heart Lung and Circulation, August 2025, Elsevier

    Vijay Rajagopal

  9. Energy-based modelling of single actin filament polymerization using bond graphs

    Article • Journal of The Royal Society Interface, January 2025, Royal Society Publishing

    Vijay Rajagopal, Professor Peter J Gawthrop

  10. Exploring Design-Based Research as a framework for addressing pedagogical problems faced by higher education

    Article • ASCILITE Publications, November 2024, Office of the Academic Executive Director, University of Tasmania

    Vijay Rajagopal

  11. Energy-based Modelling of Single Actin Filament Polymerisation Using Bond Graphs

    Article • June 2024, Cold Spring Harbor Laboratory Press

    Vijay Rajagopal, Professor Peter J Gawthrop

  12. Genome-wide identification of replication fork stalling/pausing sites and the interplay between RNA Pol II transcription and DNA replication progression

    Article • Genome Biology, May 2024, Springer Science + Business Media

    Vijay Rajagopal

  13. Optimizing coupling layer and superstrate thickness in attachable acoustofluidic devices

    Article • Ultrasonics, February 2024, Elsevier

    Vijay Rajagopal

  14. Critical review of single-cell mechanotyping approaches for biomedical applications

    Article • Lab on a Chip, January 2024, Royal Society of Chemistry

    Vijay Rajagopal

  15. BondGraphs.jl: composable energy-based modelling in systems biology

    Article • Bioinformatics, September 2023, Oxford University Press (OUP)

    Vijay Rajagopal

  16. InsP3R-RyR channel crosstalk augments sarcoplasmic reticulum Ca2+ release and arrhythmogenic activity in post-MI pig cardiomyocytes

    Article • Journal of Molecular and Cellular Cardiology, June 2023, Elsevier

    Vijay Rajagopal

  17. Frontiers of Mathematical Biology: A workshop honouring Professor Edmund Crampin

    Article • Mathematical Biosciences, May 2023, Elsevier

    Vijay Rajagopal

  18. BondGraphs.jl: Composable energy-based modelling in systems biology

    Article • April 2023, Cold Spring Harbor Laboratory Press

    Vijay Rajagopal

  19. Energy dependence of signalling dynamics and robustness in bacterial two component systems

    Article • February 2023, Cold Spring Harbor Laboratory Press

    Vijay Rajagopal

  20. IP3R activity increases propensity of RyR-mediated sparks by elevating dyadic [Ca2＋]

    Article • Mathematical Biosciences, January 2023, Elsevier

    Vijay Rajagopal

  21. Sub-wavelength acoustic stencil for tailored micropatterning

    Article • Lab on a Chip, January 2023, Royal Society of Chemistry

    Vijay Rajagopal

  22. CardioVinci: building blocks for virtual cardiac cells using deep learning

    Article • Philosophical Transactions of the Royal Society B Biological Sciences, October 2022, Royal Society Publishing

    Vijay Rajagopal

  23. Effects of altered cellular ultrastructure on energy metabolism in diabetic cardiomyopathy: an in silico study

    Article • Philosophical Transactions of the Royal Society B Biological Sciences, October 2022, Royal Society Publishing

    Vijay Rajagopal

  24. New revelations on the interplay between cardiomyocyte architecture and cardiomyocyte function in growth, health, and disease: a brief introduction

    Article • Philosophical Transactions of the Royal Society B Biological Sciences, October 2022, Royal Society Publishing

    Vijay Rajagopal

  25. The Cell Physiome: What Do We Need in a Computational Physiology Framework for Predicting Single-Cell Biology?

    Article • Annual Review of Biomedical Data Science, August 2022, Annual Reviews

    Vijay Rajagopal

  26. Role of actin filaments and cis binding in cadherin clustering and patterning

    Article • PLoS Computational Biology, July 2022, PLOS

    Vijay Rajagopal

  27. Effects of altered cellular ultrastructure on energy metabolism in diabetic cardiomyopathy – an in-silico study

    Article • May 2022, Cold Spring Harbor Laboratory Press

    Vijay Rajagopal

  28. Cortical tension initiates the positive feedback loop between cadherin and F-actin

    Article • Biophysical Journal, February 2022, Elsevier

    Vijay Rajagopal

  29. Paradoxes of Hymenoptera flight muscles, extreme machines

    Article • Biophysical Reviews, February 2022, Springer Science + Business Media

    Vijay Rajagopal

  30. Multimodal imaging reveals membrane skeleton reorganisation during reticulocyte maturation and differences in dimple and rim regions of mature erythrocytes

    Article • Journal of Structural Biology X, January 2022, Elsevier

    Vijay Rajagopal

  31. Improving student outcomes through transdisciplinary curriculum design in biomedical engineering

    Article • January 2022, Curran Associates, Inc.

    Vijay Rajagopal

  32. Periodic Rayleigh streaming vortices and Eckart flow arising from traveling-wave-based diffractive acoustic fields

    Article • Physical Review E, October 2021, American Physical Society (APS)

    Vijay Rajagopal

  33. Respiration mask waveguide optimisation for maximised speech intelligibility

    Article • The Journal of the Acoustical Society of America, September 2021, Acoustical Society of America (ASA)

    Vijay Rajagopal

  34. CardioVinci: building blocks for virtual cardiac cells using deep learning

    Article • August 2021, Cold Spring Harbor Laboratory Press

    Vijay Rajagopal

  35. A toolbox for generating scalable mitral valve morphometric models

    Article • Computers in Biology and Medicine, August 2021, Elsevier

    Vijay Rajagopal

  36. EGFRvIII Promotes Cell Survival during Endoplasmic Reticulum Stress through a Reticulocalbin 1-Dependent Mechanism

    Article • Cancers, March 2021, MDPI AG

    Vijay Rajagopal

  37. Cortical Tension Initiates the Positive Feedback Loop Between E-cadherin and F-actin

    Article • February 2021, Cold Spring Harbor Laboratory Press

    Vijay Rajagopal

  38. EM-net: Deep learning for electron microscopy image segmentation

    Article • January 2021, Institute of Electrical & Electronics Engineers (IEEE)

    Vijay Rajagopal

  39. EM-stellar: benchmarking deep learning for electron microscopy image segmentation

    Article • Bioinformatics, January 2021, Oxford University Press (OUP)

    Vijay Rajagopal

  40. Unconventional acoustic approaches for localized and designed micromanipulation

    Article • Lab on a Chip, January 2021, Royal Society of Chemistry

    Vijay Rajagopal

  41. Modelling cardiomyocyte energetics

    Article • December 2020, Institute of Physics Publishing

    Vijay Rajagopal

  42. Surface area‐to‐volume ratio, not cellular viscoelasticity, is the major determinant of red blood cell traversal through small channels

    Article • Cellular Microbiology, October 2020, Wiley

    Vijay Rajagopal

  43. Membrane Tension Can Enhance Adaptation to Maintain Polarity of Migrating Cells

    Article • Biophysical Journal, October 2020, Elsevier

    Vijay Rajagopal

  44. An in-silico study to determine whether changes to mitochondria organization through engineered mitochondrial dynamics can enhance bioenergetics in cardiomyocytes

    Article • September 2020, Cold Spring Harbor Laboratory Press

    Vijay Rajagopal

  45. Ca2+ Release via IP3 Receptors Shapes the Cardiac Ca2+ Transient for Hypertrophic Signaling

    Article • Biophysical Journal, September 2020, Elsevier

    Vijay Rajagopal

  46. IP3R activity increases frequency of RyR-mediated sparks by elevating dyadic Ca2+

    Article • August 2020, Cold Spring Harbor Laboratory Press

    Vijay Rajagopal

  47. EM-stellar: benchmarking deep learning for electron microscopy image segmentation

    Article • July 2020, Cold Spring Harbor Laboratory Press

    Vijay Rajagopal

  48. Surface area-to-volume ratio, not cellular rigidity, determines red blood cell traversal through small capillaries

    Article • July 2020, Cold Spring Harbor Laboratory Press

    Vijay Rajagopal

  49. Membrane tension can enhance adaptation to maintain polarity of migrating cells

    Article • April 2020, Cold Spring Harbor Laboratory Press

    Vijay Rajagopal

  50. EM-net: Deep learning for electron microscopy image segmentation

    Article • February 2020, Cold Spring Harbor Laboratory Press

    Vijay Rajagopal

  51. Efficient estimation of load‐free left ventricular geometry and passive myocardial properties using principal component analysis.

    Article • International Journal for Numerical Methods in Biomedical Engineering, January 2020, Wiley

    Vijay Rajagopal, Professor Alistair A Young

  52. Automated segmentation of cardiomyocyte Z-disks from high-throughput scanning electron microscopy data

    Article • BMC Medical Informatics and Decision Making, December 2019, Springer Science + Business Media

    Vijay Rajagopal

  53. Assessing Cardiomyocyte Excitation-Contraction Coupling Site Detection From Live Cell Imaging Using a Structurally-Realistic Computational Model of Calcium Release

    Article • Frontiers in Physiology, October 2019, Frontiers

    Vijay Rajagopal

  54. How Does the Internal Structure of Cardiac Muscle Cells Regulate Cellular Metabolism?

    Article • Microscopy and Microanalysis, August 2019, Oxford University Press (OUP)

    Vijay Rajagopal

  55. Detecting RyR clusters with CaCLEAN: influence of spatial distribution and structural heterogeneity

    Article • February 2019, Cold Spring Harbor Laboratory Press

    Vijay Rajagopal

  56. Multimodal analysis ofPlasmodium knowlesi‐infected erythrocytes reveals large invaginations, swelling of the host cell, and rheological defects

    Article • Cellular Microbiology, February 2019, Wiley

    Vijay Rajagopal

  57. Insights on the impact of mitochondrial organisation on bioenergetics in high-resolution computational models of cardiac cell architecture

    Article • PLoS Computational Biology, December 2018, PLOS

    Vijay Rajagopal

  58. Automated framework to reconstruct 3D model of cardiac Z-disk: an image processing approach

    Article • December 2018, Institute of Electrical & Electronics Engineers (IEEE)

    Vijay Rajagopal

  59. Assessment of single beat end-systolic elastance methods for quantifying ventricular contractility

    Article • Heart and Vessels, November 2018, Springer Science + Business Media

    Vijay Rajagopal

  60. An automated workflow for segmenting single adult cardiac cells from large-volume serial block-face scanning electron microscopy data

    Article • Journal of Structural Biology, June 2018, Elsevier

    Vijay Rajagopal

  61. Insights on the impact of mitochondrial organisation on bioenergetics in high-resolution computational models of cardiac cell architecture

    Article • May 2018, Cold Spring Harbor Laboratory Press

    Vijay Rajagopal

  62. Creating a Structurally Realistic Finite Element Geometric Model of a Cardiomyocyte to Study the Role of Cellular Architecture in Cardiomyocyte Systems Biology

    Article • Journal of Visualized Experiments, April 2018, MyJove Corporation

    Vijay Rajagopal

  63. An Automated Workflow for Segmenting Single Adult Cardiac Cells from Large-Volume Serial Block-Face Scanning Electron Microscopy Data

    Article • January 2018, Cold Spring Harbor Laboratory Press

    Vijay Rajagopal

  64. Erythrocyte β spectrin can be genetically targeted to protect mice from malaria

    Article • Blood Advances, December 2017, American Society of Hematology

    Vijay Rajagopal

  65. Computational modeling of single-cell mechanics and cytoskeletal mechanobiology

    Article • WIREs Systems Biology and Medicine, November 2017, Wiley

    Vijay Rajagopal

  66. A Semi-Automated Workflow for Segmenting Contents of Single Cardiac Cells from Serial-Block-Face Scanning Electron Microscopy Data

    Article • Microscopy and Microanalysis, July 2017, Cambridge University Press

    Vijay Rajagopal

  67. A computational study of the role of mitochondrial organization on cardiac bioenergetics

    Article • July 2017, Institute of Electrical & Electronics Engineers (IEEE)

    Vijay Rajagopal

  68. Changes in mitochondrial morphology and organization can enhance energy supply from mitochondrial oxidative phosphorylation in diabetic cardiomyopathy

    Article • AJP Cell Physiology, February 2017, American Physiological Society

    Vijay Rajagopal

  69. Examination of the Effects of Heterogeneous Organization of RyR Clusters, Myofibrils and Mitochondria on Ca2+ Release Patterns in Cardiomyocytes

    Article • PLoS Computational Biology, September 2015, PLOS

    Vijay Rajagopal

  70. Super-resolution fluorescence imaging to study cardiac biophysics: α-actinin distribution and Z-disk topologies in optically thick cardiac tissue slices

    Article • Progress in Biophysics and Molecular Biology, August 2014, Elsevier

    Vijay Rajagopal

  71. Breast lesion co-localisation between X-ray and MR images using finite element modelling

    Article • Medical Image Analysis, December 2013, Elsevier

    Vijay Rajagopal

  72. Modelling Prone to Supine Breast Deformation Under Gravity Loading Using Heterogeneous Finite Element Models

    Article • January 2012, Springer Science + Business Media

    Vijay Rajagopal

  73. OpenCMISS: A multi-physics & multi-scale computational infrastructure for the VPH/Physiome project

    Article • Progress in Biophysics and Molecular Biology, October 2011, Elsevier

    Dr Soroush Safaei, David P Nickerson, Vijay Rajagopal, Prof Alejandro F Frangi

  74. Identification of mechanical properties of heterogeneous soft bodies using gravity loading

    Article • International Journal for Numerical Methods in Biomedical Engineering, March 2011, Wiley

    Vijay Rajagopal

  75. Identification of mechanical properties of heterogeneous soft bodies using gravity loading

    Article • International Journal for Numerical Methods in Biomedical Engineering, February 2011, Wiley

    Vijay Rajagopal

  76. Patient-Specific Modeling of Breast Biomechanics with Applications to Breast Cancer Detection and Treatment

    Article • January 2011, Springer Science + Business Media

    Vijay Rajagopal

  77. Mapping Breast Cancer Between Clinical X-Ray and MR Images

    Article • January 2011, Springer Science + Business Media

    Vijay Rajagopal

  78. Stochastic modelling of cardiac cell structure

    Article • August 2010, Institute of Electrical & Electronics Engineers (IEEE)

    Dr Michael J O'Sullivan, Vijay Rajagopal

  79. Breast Image Registration by Combining Finite Elements and Free-Form Deformations

    Article • January 2010, Springer Science + Business Media

    Vijay Rajagopal

  80. Mapping Microcalcifications Between 2D Mammograms and 3D MRI Using a Biomechanical Model of the Breast

    Article • January 2010, Springer Science + Business Media

    Vijay Rajagopal

  81. Method for Validating Breast Compression Models Using Normalised Cross-Correlation

    Article • January 2010, Springer Science + Business Media

    Vijay Rajagopal

  82. Modeling breast biomechanics for multi-modal image analysis-successes and challenges

    Article • WIREs Systems Biology and Medicine, October 2009, Wiley

    Vijay Rajagopal

  83. Modeling of the mechanical function of the human gastroesophageal junction using an anatomically realistic three-dimensional model

    Article • Journal of Biomechanics, August 2009, Elsevier

    Vijay Rajagopal

  84. Correlation of breast image alignment using biomechanical modelling

    Article • February 2009, SPIE

    Vijay Rajagopal

  85. Creating Individual-specific Biomechanical Models of the Breast for Medical Image Analysis

    Article • Academic Radiology, November 2008, Elsevier

    Vijay Rajagopal

  86. Biomechanical modelling for breast image registration

    Article • March 2008, SPIE

    Vijay Rajagopal

  87. Frictional contact mechanics methods for soft materials: Application to tracking breast cancers

    Article • Journal of Biomechanics, January 2008, Elsevier

    Vijay Rajagopal

  88. Modelling Mammographic Compression of the Breast

    Article • January 2008, Springer Science + Business Media

    Vijay Rajagopal

  89. A biomechanical model of mammographic compressions

    Article • Biomechanics and Modeling in Mechanobiology, January 2007, Springer Science + Business Media

    Vijay Rajagopal

  90. Determining the finite elasticity reference state from a loaded configuration

    Article • International Journal for Numerical Methods in Engineering, January 2007, Wiley

    Vijay Rajagopal

  91. Finite Element Modelling of Breast Biomechanics: Directly Calculating the Reference State

    Article • August 2006, Institute of Electrical & Electronics Engineers (IEEE)

    Vijay Rajagopal

  92. Computational modeling of the breast during mammography for tumor tracking

    Article • April 2005, SPIE

    Vijay Rajagopal

  93. The Breast Biomechanics Reference State for Multi-modal Image Analysis

    Article • Springer Science + Business Media

    Vijay Rajagopal

  94. Towards Tracking Breast Cancer Across Medical Images Using Subject-Specific Biomechanical Models

    Article • Springer Science + Business Media

    Vijay Rajagopal