All Stories

  1. Oxidative stress and signaling through EGFR and PKA pathways converge on the nuclear transport factor RanBP1
  2. Yeast profilin mutants inhibit classical nuclear import and alter the balance between actin and tubulin levels
  3. Curcumin and butyrate induce fibroblast senescence without the emergence of fibrosis biomarkers
  4. Valosin containing protein (VCP): initiator, modifier, and potential drug target for neurodegenerative diseases
  5. Combining Pr3+-Doped Nanoradiosensitizers and Endogenous Protoporphyrin IX for X-ray-Mediated Photodynamic Therapy of Glioblastoma Cells
  6. Multiple pathways promote microtubule stabilization in senescent intestinal epithelial cells
  7. CD26 is a senescence marker associated with reduced immunopotency of human adipose tissue-derived multipotent mesenchymal stromal cells
  8. Targeting nanoparticles to malignant tumors
  9. Curcumin nanoformulations to combat aging-related diseases
  10. Nucleolar Organization and Functions in Health and Disease
  11. The Cytoskeleton as Regulator of Cell Signaling Pathways
  12. Exploring near-infrared absorbing nanocarriers to overcome cancer drug resistance
  13. MSC - targets for atherosclerosis therapy
  14. Cytoplasmic RNA Granules in Somatic Maintenance
  15. Cytoplasmic stress granules: Dynamic modulators of cell signaling and disease
  16. AMP Kinase Activation Alters Oxidant-Induced Stress Granule Assembly by Modulating Cell Signaling and Microtubule Organization
  17. Immunofluorescence staining of kidney sections to monitor ischemia-induced damage
  18. Gold Nanoparticles Impinge on Nucleoli and the Stress Response in MCF7 Breast Cancer Cells
  19. Quantitative analysis of the interplay between hsc70 and its co-chaperone HspBP1
  20. Data in support of 5′AMP-activated protein kinase alpha regulates stress granule biogenesis
  21. Hsc70 chaperone activity underlies Trio GEF function in axon growth and guidance induced by netrin-1
  22. Age, atherosclerosis and type 2 diabetes reduce human mesenchymal stromal cell-mediated T-cell suppression
  23. Impact of Leishmania Infection on Host Macrophage Nuclear Physiology and Nucleopore Complex Integrity
  24. Enhanced killing of SCC17B human head and neck squamous cell carcinoma cells after photodynamic therapy plus fenretinide via the de novo sphingolipid biosynthesis pathway and apoptosis
  25. Detecting changes in the mitochondrial membrane potential by quantitative fluorescence microscopy
  26. Off to the Organelles - Killing Cancer Cells with Targeted Gold Nanoparticles
  27. Ceramide synthase inhibitor fumonisin B1 inhibits apoptotic cell death in SCC17B human head and neck squamous carcinoma cells after Pc4 photosensitization
  28. Nucleoli and Stress Granules: Connecting Distant Relatives
  29. Gold nanoparticles induce nuclear damage in breast cancer cells, which is further amplified by hyperthermia
  30. Pharmacological AMP Kinase Activators Target the Nucleolar Organization and Control Cell Proliferation
  31. Identification of Novel Markers That Demarcate the Nucleolus during Severe Stress and Chemotherapeutic Treatment
  32. Contributions of AMP kinase to the Pathogenesis of Type 2 Diabetes and Neurodegenerative Diseases
  33. Identification of Novel Stress Granule Components That Are Involved in Nuclear Transport
  34. Automated Detection and Quantification of Granular Cell Compartments
  35. Implications of multipotent mesenchymal stromal cell aging
  36. Chaperones and Multitasking Proteins in the Nucleolus
  37. Spatial Proteomics Sheds Light on the Biology of Nucleolar Chaperones
  38. Nuclear Transport: A Switch for the Oxidative Stress—Signaling Circuit?
  39. AMP kinase: the missing link between type 2 diabetes and neurodegenerative diseases?
  40. Targeting AMPK for Therapeutic Intervention in Type 2 Diabetes
  41. Exploring the Nucleolar Proteome: Novel Concepts for Chaperone Trafficking and Function
  42. Computer-based fluorescence quantification: a novel approach to study nucleolar biology
  43. Nuclear envelopes show cell-type specific sensitivity for the permeabilization with digitonin.
  44. Chaperones and multitasking proteins in the nucleolus: networking together for survival?
  45. Traffic control at the nuclear pore
  46. Traffic control at the nuclear pore
  47. Dissecting the Signaling Events That Impact Classical Nuclear Import and Target Nuclear Transport Factors
  48. Interplay between MEK and PI3 kinase signaling regulates the subcellular localization of protein kinases ERK1/2 and Akt upon oxidative stress
  49. Optimized immunofluorescence staining protocol to detect the nucleoporin Nup98 in different subcellular compartments
  50. Oxidative stress mislocalizes and retains transport factor importin-α and nucleoporins Nup153 and Nup88 in nuclei where they generate high molecular mass complexes
  51. The localization of nuclear exporters of the importin-β family is regulated by Snf1 kinase, nutrient supply and stress
  52. The carrier Msn5p/Kap142p promotes nuclear export of the hsp70 Ssa4p and relocates in response to stress
  53. The N-terminal domain of the mammalian nucleoporin p62 interacts with other nucleoporins of the FXFG family during interphase
  54. Rapid purification of the outer mitochondrial membrane protein Por1p from Saccharomyces cerevisiae
  55. Starvation Promotes Nuclear Accumulation of the hsp70 Ssa4p in Yeast Cells
  56. Nonlamin components of the lamina: a paucity of proteins
  57. Targeting of the mammalian nucleoporin p62 to the nuclear envelope in the yeast Saccharomyces cerevisiae and HeLa cells
  58. Overexpression of the nucleoporin p62 induces nuclear fragmentation in HeLa cells
  59. Nucleocytoplasmic trafficking of proteins: With or without Ran?
  60. Targeting of the mammalian nucleoporin p62 to the nuclear envelope in the yeast Saccharomyces cerevisiae and HeLa cells
  61. Velcro in the nuclear envelope: LBR and LAPs
  62. Diffusion of Proteins Across the Nuclear Envelope of HeLa Cells
  63. The small GTPase Gsp1p binds to the repeat domain of the nucleoporin Nsp1p
  64. In VivoAnalysis of Nuclear Protein Traffic in Mammalian Cells
  65. Monitoring Nuclear Transport in HeLa Cells Using the Green Fluorescent Protein
  66. The yeast nucleoporin Nsp1 binds nuclear localization sequences in vitro
  67. Construction and in vivo analysis of new split lactose permeases
  68. Limited proteolysis of chicken gizzard 5′-nucleotidase
  69. Affinity labelling of 5′-nucleotidases with 5′-p-fluorosulphonylbenzoyladenosine
  70. Evidence for the direct interaction of chicken gizzard 5′-nucleotidase with laminin and fibronectin
  71. Studies on Transposable Element Ac of Zea Mays
  72. The N-terminal region of Escherichia coli lactose permease mediates membrane contact of the nascent polypeptide chain
  73. Limited proteolysis of lactose permease from Escherichia coli