All Stories

  1. Bioorthogonal Non-Canonical Amino Acid Tagging (BONCAT) to detect newly synthesized proteins in cells and their secretome
  2. Pifithrin-µ Induces Stress Granule Formation, Regulates Cell Survival, and Rewires Cellular Signaling
  3. Oxidative stress and signaling through EGFR and PKA pathways converge on the nuclear transport factor RanBP1
  4. Silica-coated LiYF4:Yb3+, Tm3+ upconverting nanoparticles are non-toxic and activate minor stress responses in mammalian cells
  5. Yeast profilin mutants inhibit classical nuclear import and alter the balance between actin and tubulin levels
  6. Curcumin and butyrate induce fibroblast senescence without the emergence of fibrosis biomarkers
  7. Valosin containing protein (VCP): initiator, modifier, and potential drug target for neurodegenerative diseases
  8. Combining Pr3+-Doped Nanoradiosensitizers and Endogenous Protoporphyrin IX for X-ray-Mediated Photodynamic Therapy of Glioblastoma Cells
  9. Multiple pathways promote microtubule stabilization in senescent intestinal epithelial cells
  10. CD26 is a senescence marker associated with reduced immunopotency of human adipose tissue-derived multipotent mesenchymal stromal cells
  11. Targeting nanoparticles to malignant tumors
  12. Curcumin nanoformulations to combat aging-related diseases
  13. Evaluation of Lanthanide-Doped Upconverting Nanoparticles for in Vitro and in Vivo Applications
  14. The Co-Chaperone HspBP1 Is a Novel Component of Stress Granules that Regulates Their Formation
  15. Nucleolar Organization and Functions in Health and Disease
  16. The Cytoskeleton as Regulator of Cell Signaling Pathways
  17. Exploring near-infrared absorbing nanocarriers to overcome cancer drug resistance
  18. Cellular senescence is associated with reorganization of the microtubule cytoskeleton
  19. MSC - targets for atherosclerosis therapy
  20. Inhibition of glioblastoma cell proliferation, invasion, and mechanism of action of a novel hydroxamic acid hybrid molecule
  21. Cytoplasmic RNA Granules in Somatic Maintenance
  22. Gold nanourchins and celastrol reorganize the nucleo- and cytoskeleton of glioblastoma cells
  23. The effects of lanthanide-doped upconverting nanoparticles on cancer cell biomarkers
  24. Cytoplasmic stress granules: Dynamic modulators of cell signaling and disease
  25. Dissecting the molecular mechanisms that impair stress granule formation in aging cells
  26. AMP Kinase Activation Alters Oxidant-Induced Stress Granule Assembly by Modulating Cell Signaling and Microtubule Organization
  27. Super-resolution microscopy reveals a golden kiss of death to mitochondria
  28. Immunofluorescence staining of kidney sections to monitor ischemia-induced damage
  29. Gold Nanoparticles Impinge on Nucleoli and the Stress Response in MCF7 Breast Cancer Cells
  30. Quantitative analysis of the interplay between hsc70 and its co-chaperone HspBP1
  31. Data in support of 5′AMP-activated protein kinase alpha regulates stress granule biogenesis
  32. Hsc70 chaperone activity underlies Trio GEF function in axon growth and guidance induced by netrin-1
  33. Age, atherosclerosis and type 2 diabetes reduce human mesenchymal stromal cell-mediated T-cell suppression
  34. Impact of Leishmania Infection on Host Macrophage Nuclear Physiology and Nucleopore Complex Integrity
  35. Enhanced killing of SCC17B human head and neck squamous cell carcinoma cells after photodynamic therapy plus fenretinide via the de novo sphingolipid biosynthesis pathway and apoptosis
  36. Detecting changes in the mitochondrial membrane potential by quantitative fluorescence microscopy
  37. Off to the Organelles - Killing Cancer Cells with Targeted Gold Nanoparticles
  38. Ceramide synthase inhibitor fumonisin B1 inhibits apoptotic cell death in SCC17B human head and neck squamous carcinoma cells after Pc4 photosensitization
  39. Nucleoli and Stress Granules: Connecting Distant Relatives
  40. Gold nanoparticles induce nuclear damage in breast cancer cells, which is further amplified by hyperthermia
  41. Pharmacological AMP Kinase Activators Target the Nucleolar Organization and Control Cell Proliferation
  42. Identification of Novel Markers That Demarcate the Nucleolus during Severe Stress and Chemotherapeutic Treatment
  43. Contributions of AMP kinase to the Pathogenesis of Type 2 Diabetes and Neurodegenerative Diseases
  44. Identification of Novel Stress Granule Components That Are Involved in Nuclear Transport
  45. Automated Detection and Quantification of Granular Cell Compartments
  46. Implications of multipotent mesenchymal stromal cell aging
  47. Chaperones and Multitasking Proteins in the Nucleolus
  48. Spatial Proteomics Sheds Light on the Biology of Nucleolar Chaperones
  49. Nuclear Transport: A Switch for the Oxidative Stress—Signaling Circuit?
  50. AMP kinase: the missing link between type 2 diabetes and neurodegenerative diseases?
  51. Targeting AMPK for Therapeutic Intervention in Type 2 Diabetes
  52. Exploring the Nucleolar Proteome: Novel Concepts for Chaperone Trafficking and Function
  53. Computer-based fluorescence quantification: a novel approach to study nucleolar biology
  54. Nuclear envelopes show cell-type specific sensitivity for the permeabilization with digitonin.
  55. Chaperones and multitasking proteins in the nucleolus: networking together for survival?
  56. Traffic control at the nuclear pore
  57. Traffic control at the nuclear pore
  58. Dissecting the Signaling Events That Impact Classical Nuclear Import and Target Nuclear Transport Factors
  59. Interplay between MEK and PI3 kinase signaling regulates the subcellular localization of protein kinases ERK1/2 and Akt upon oxidative stress
  60. Optimized immunofluorescence staining protocol to detect the nucleoporin Nup98 in different subcellular compartments
  61. Oxidative stress mislocalizes and retains transport factor importin-α and nucleoporins Nup153 and Nup88 in nuclei where they generate high molecular mass complexes
  62. The localization of nuclear exporters of the importin-β family is regulated by Snf1 kinase, nutrient supply and stress
  63. The carrier Msn5p/Kap142p promotes nuclear export of the hsp70 Ssa4p and relocates in response to stress
  64. The N-terminal domain of the mammalian nucleoporin p62 interacts with other nucleoporins of the FXFG family during interphase
  65. Rapid purification of the outer mitochondrial membrane protein Por1p from Saccharomyces cerevisiae
  66. Starvation Promotes Nuclear Accumulation of the hsp70 Ssa4p in Yeast Cells
  67. Nonlamin components of the lamina: a paucity of proteins
  68. Targeting of the mammalian nucleoporin p62 to the nuclear envelope in the yeast Saccharomyces cerevisiae and HeLa cells
  69. Overexpression of the nucleoporin p62 induces nuclear fragmentation in HeLa cells
  70. Nucleocytoplasmic trafficking of proteins: With or without Ran?
  71. Targeting of the mammalian nucleoporin p62 to the nuclear envelope in the yeast Saccharomyces cerevisiae and HeLa cells
  72. Velcro in the nuclear envelope: LBR and LAPs
  73. Diffusion of Proteins Across the Nuclear Envelope of HeLa Cells
  74. The small GTPase Gsp1p binds to the repeat domain of the nucleoporin Nsp1p
  75. In VivoAnalysis of Nuclear Protein Traffic in Mammalian Cells
  76. Monitoring Nuclear Transport in HeLa Cells Using the Green Fluorescent Protein
  77. The yeast nucleoporin Nsp1 binds nuclear localization sequences in vitro
  78. Construction and in vivo analysis of new split lactose permeases
  79. Limited proteolysis of chicken gizzard 5′-nucleotidase
  80. Affinity labelling of 5′-nucleotidases with 5′-p-fluorosulphonylbenzoyladenosine
  81. Evidence for the direct interaction of chicken gizzard 5′-nucleotidase with laminin and fibronectin
  82. Studies on Transposable Element Ac of Zea Mays
  83. The N-terminal region of Escherichia coli lactose permease mediates membrane contact of the nascent polypeptide chain
  84. Limited proteolysis of lactose permease from Escherichia coli