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  1. A new horizon in the phosphorylated sites of AGA: the structural impact of C163S mutation in aspartylglucosaminuria through molecular dynamics simulation

    Article • Journal of Biomolecular Structure and Dynamics, June 2023, Taylor & Francis

    Dr. Udhaya Kumar S

  2. Molecular dynamics simulations corroborate recombinant expression studies carried out on three αIIb β‐propeller mutations reported in Indian Glanzmann thrombasthenia patients

    Article • Journal of Cellular Biochemistry, May 2023, Wiley

    Dr. Udhaya Kumar S

  3. Exome sequence analysis of rare frequency variants in Late-Onset Alzheimer Disease

    Article • Metabolic Brain Disease, May 2023, Springer Science + Business Media

    Dr. Udhaya Kumar S

  4. Gene network interaction analysis to elucidate the antimicrobial resistance mechanisms in the Clostridium difficile

    Article • Microbial Pathogenesis, May 2023, Elsevier

    Dr. Udhaya Kumar S

  5. Integrated gene network analysis sheds light on understanding the progression of Osteosarcoma

    Article • Frontiers in Medicine, April 2023, Frontiers

    Dr. Udhaya Kumar S

  6. The targeted next-generation sequence revealed SMAD4, AKT1, and TP53 mutations from circulating cell-free DNA of breast cancer and its effect on protein structure – A computational approach

    Article • Journal of Biomolecular Structure and Dynamics, April 2023, Taylor & Francis

    Dr. Udhaya Kumar S

  7. HPV and molecular mimicry in systemic lupus erythematosus and an impact of compiling B-cell epitopes and MHC-class II binding profiles with in silico evidence

    Article • Journal of Biomolecular Structure and Dynamics, February 2023, Taylor & Francis

    Dr. Udhaya Kumar S

  8. Identification of dysregulated canonical pathways associated with pathogenesis and progression of Amyotrophic Lateral Sclerosis—An integrated bioinformatics approach

    Article • January 2023, Elsevier

    Dr. Udhaya Kumar S

  9. CDK regulators—Cell cycle progression or apoptosis—Scenarios in normal cells and cancerous cells

    Article • January 2023, Elsevier

    Dr. Udhaya Kumar S

  10. Controlling cell proliferation by targeting cyclin-dependent kinase 6 using drug repurposing approach

    Article • January 2023, Elsevier

    Dr. Udhaya Kumar S

  11. Elucidating the mechanism of antimicrobial resistance in Mycobacterium tuberculosis using gene interaction networks

    Article • January 2023, Elsevier

    Dr. Udhaya Kumar S

  12. Molecular characterization of circadian gene expression and its correlation with survival percentage in colorectal cancer patients

    Article • January 2023, Elsevier

    Dr. Udhaya Kumar S

  13. Multispectroscopic, virtual and in vivo insights into the photoaging defense mediated by the natural food colorant bixin

    Article • Food & Function, January 2023, Royal Society of Chemistry

    Dr. Udhaya Kumar S

  14. Structure-based virtual screening to identify potential lipase inhibitors to reduce lipid storage in Wolman disorder

    Article • January 2023, Elsevier

    Dr. Udhaya Kumar S

  15. Analysis of signaling cascades from myeloma cells treated with pristimerin

    Article • January 2023, Elsevier

    Dr. Udhaya Kumar S

  16. Effects of the pathological E200K mutation on human prion protein: A computational screening and molecular dynamics approach

    Article • Journal of Cellular Biochemistry, December 2022, Wiley

    Dr. Udhaya Kumar S

  17. An integrated investigation of structural and pathway alteration caused by PIK3CA and TP53 mutations identified in cfDNA of metastatic breast cancer

    Article • Journal of Cellular Biochemistry, December 2022, Wiley

    Dr. Udhaya Kumar S

  18. SARS-CoV-2 vaccine-breakthrough infections (VBIs) by Omicron (B.1.1.529) variant and consequences in structural and functional impact

    Article • December 2022, Cold Spring Harbor Laboratory Press

    Dr. Udhaya Kumar S

  19. Whole-exome sequencing analysis of NSCLC reveals the pathogenic missense variants from cancer-associated genes

    Article • Computers in Biology and Medicine, September 2022, Elsevier

    Dr. Udhaya Kumar S

  20. Identification of potential inhibitors, conformational dynamics, and mechanistic insights into mutant Kirsten rat sarcoma virus (G13D) driven cancers

    Article • Journal of Cellular Biochemistry, July 2022, Wiley

    Dr. Udhaya Kumar S

  21. Computational and structural investigation of Palmitoyl-Protein Thioesterase 1 (PPT1) protein causing Neuronal Ceroid Lipofuscinoses (NCL)

    Article • January 2022, Elsevier

    Dr. Udhaya Kumar S

  22. Deciphering the effect of mutations in MMAA protein causing methylmalonic acidemia—A computational approach

    Article • January 2022, Elsevier

    Dr. Udhaya Kumar S

  23. Investigation of differentially expressed genes and dysregulated pathways involved in multiple sclerosis

    Article • January 2022, Elsevier

    Dr. Udhaya Kumar S

  24. A review of bioinformatics tools and web servers in different microarray platforms used in cancer research

    Article • January 2022, Elsevier

    Dr. Udhaya Kumar S

  25. Integrative ontology and pathway-based approach identifies distinct molecular signatures in transcriptomes of esophageal squamous cell carcinoma

    Article • January 2022, Elsevier

    Dr. Udhaya Kumar S

  26. Computational structural assessment of BReast CAncer type 1 susceptibility protein (BRCA1) and BRCA1-Associated Ring Domain protein 1 (BARD1) mutations on the protein-protein interface

    Article • January 2022, Elsevier

    Dr. Udhaya Kumar S

  27. Mutations in G6PC2 gene with increased risk for development of type 2 diabetes: Understanding via computational approach

    Article • January 2022, Elsevier

    Dr. Udhaya Kumar S

  28. A computational model revealing the immune-related hub genes and key pathways involved in rheumatoid arthritis (RA)

    Article • January 2022, Elsevier

    Dr. Udhaya Kumar S

  29. Understanding the activating mechanism of the immune system against COVID-19 by Traditional Indian Medicine: Network pharmacology approach

    Article • January 2022, Elsevier

    Dr. Udhaya Kumar S

  30. A computational overview on phylogenetic characterization, pathogenic mutations, and drug targets for Ebola virus disease

    Article • Current Opinion in Pharmacology, December 2021, Elsevier

    Dr. Udhaya Kumar S

  31. Computational validation of ABCB1 gene polymorphism and its effect on tacrolimus dose concentration/levels in renal transplant individuals of South India

    Article • Computers in Biology and Medicine, December 2021, Elsevier

    Dr. Udhaya Kumar S

  32. Computational investigation to identify potent inhibitors of the GTPase-Kirsten RAt sarcoma virus (K-Ras) mutants G12C and G12D

    Article • Computers in Biology and Medicine, December 2021, Elsevier

    Dr. Udhaya Kumar S

  33. Siddha Medicine and Computer Modeling: A Treasure for SARS-CoV-2 Treatment

    Article • November 2021, Springer Science + Business Media

    Dr. Udhaya Kumar S

  34. Unraveling the versatility of CCD4: Metabolic engineering, transcriptomic and computational approaches

    Article • Plant Science, September 2021, Elsevier

    Dr. Udhaya Kumar S

  35. Residue interaction networks of K-Ras protein with water molecules identifies the potential role of switch II and P-loop

    Article • Computers in Biology and Medicine, August 2021, Elsevier

    Dr. Udhaya Kumar S

  36. Comparison of potential inhibitors and targeting fat mass and obesity‐associated protein causing diabesity through docking and molecular dynamics strategies

    Article • Journal of Cellular Biochemistry, July 2021, Wiley

    Dr. Udhaya Kumar S

  37. Structure-Based Virtual Screening to Identify Novel Potential Compound as an Alternative to Remdesivir to Overcome the RdRp Protein Mutations in SARS-CoV-2

    Article • Frontiers in Molecular Biosciences, April 2021, Frontiers

    Dr. Udhaya Kumar S

  38. A review of novel coronavirus disease (COVID-19): based on genomic structure, phylogeny, current shreds of evidence, candidate vaccines, and drug repurposing

    Article • 3 Biotech, March 2021, Springer Science + Business Media

    Dr. Udhaya Kumar S

  39. Molecular dynamics, residue network analysis, and cross-correlation matrix to characterize the deleterious missense mutations in GALE causing galactosemia III

    Article • Cell Biochemistry and Biophysics, February 2021, Springer Science + Business Media

    Dr. Udhaya Kumar S

  40. A systemic approach to explore the mechanisms of drug resistance and altered signaling cascades in extensively drug-resistant tuberculosis

    Article • January 2021, Elsevier

    Dr. Udhaya Kumar S

  41. An integrative analysis to distinguish between emphysema (EML) and alpha-1 antitrypsin deficiency-related emphysema (ADL)—A systems biology approach

    Article • January 2021, Elsevier

    Dr. Udhaya Kumar S

  42. Investigating mutations at the hotspot position of the ERBB2 and screening for the novel lead compound to treat breast cancer – a computational approach

    Article • January 2021, Elsevier

    Dr. Udhaya Kumar S

  43. Network analysis of transcriptomics data for the prediction and prioritization of membrane-associated biomarkers for idiopathic pulmonary fibrosis (IPF) by bioinformatics approach

    Article • January 2021, Elsevier

    Dr. Udhaya Kumar S

  44. Deciphering the Role of Filamin B Calponin-Homology Domain in Causing the Larsen Syndrome, Boomerang Dysplasia, and Atelosteogenesis Type I Spectrum Disorders via a Computational Approach

    Article • Molecules, November 2020, MDPI AG

    Dr. Udhaya Kumar S

  45. Involvement of Essential Signaling Cascades and Analysis of Gene Networks in Diabesity

    Article • Genes, October 2020, MDPI AG

    Dr. Udhaya Kumar S

  46. Mutational landscape of K-Ras substitutions at 12th position-a systematic molecular dynamics approach

    Article • Journal of Biomolecular Structure and Dynamics, October 2020, Taylor & Francis

    Dr. Udhaya Kumar S

  47. Analysis of Differentially Expressed Genes and Molecular Pathways in Familial Hypercholesterolemia Involved in Atherosclerosis: A Systematic and Bioinformatics Approach

    Article • Frontiers in Genetics, July 2020, Frontiers

    Dr. Udhaya Kumar S

  48. Kerala, India's Front Runner in Novel Coronavirus Disease (COVID-19)

    Article • Frontiers in Medicine, July 2020, Frontiers

    Dr. Udhaya Kumar S

  49. The Rise and Impact of COVID-19 in India

    Article • Frontiers in Medicine, May 2020, Frontiers

    Dr. Udhaya Kumar S

  50. Dysregulation of Signaling Pathways Due to Differentially Expressed Genes From the B-Cell Transcriptomes of Systemic Lupus Erythematosus Patients – A Bioinformatics Approach

    Article • Frontiers in Bioengineering and Biotechnology, April 2020, Frontiers

    Dr. Udhaya Kumar S

  51. Molecular dynamics simulations to decipher the structural and functional consequences of pathogenic missense mutations in the galactosylceramidase (GALC) protein causing Krabbe’s disease

    Article • Journal of Biomolecular Structure and Dynamics, March 2020, Taylor & Francis

    Dr. Udhaya Kumar S

  52. An extensive computational approach to analyze and characterize the functional mutations in the galactose-1-phosphate uridyl transferase (GALT) protein responsible for classical galactosemia

    Article • Computers in Biology and Medicine, February 2020, Elsevier

    Dr. Udhaya Kumar S

  53. Comprehensive in silico screening and molecular dynamics studies of missense mutations in Sjogren-Larsson syndrome associated with the ALDH3A2 gene

    Article • January 2020, Elsevier

    Dr. Udhaya Kumar S

  54. Computational model to analyze and characterize the functional mutations of NOD2 protein causing inflammatory disorder – Blau syndrome

    Article • January 2020, Elsevier

    Dr. Udhaya Kumar S

  55. Identification of potential inhibitors against pathogenic missense mutations of PMM2 using a structure-based virtual screening approach

    Article • Journal of Biomolecular Structure and Dynamics, December 2019, Taylor & Francis

    Dr. Udhaya Kumar S

  56. Integrative Bioinformatics Approaches to Map Potential Novel Genes and Pathways Involved in Ovarian Cancer

    Article • Frontiers in Bioengineering and Biotechnology, December 2019, Frontiers

    Dr. Udhaya Kumar S

  57. Znf76 is associated with development of the eyes, midbrain, MHB, and hindbrain in zebrafish embryos

    Article • Animal Cells and Systems, January 2019, Taylor & Francis

    Dr. Udhaya Kumar S

  58. Mutations in ARSB in MPS VI patients in India

    Article • Molecular Genetics and Metabolism Reports, September 2015, Elsevier

    Dr. Thiyagarajan Saravanamuthu, Dr. Udhaya Kumar S

  59. Functional and structural characterization of missense mutations in PAX6 gene

    Article • Frontiers in Biology, March 2015, Springer Science + Business Media

    Dr. Udhaya Kumar S