All Stories

  1. Risk stratification utilizing sequential organ failure assessment (SOFA) score, antithrombin activity, and demographic data in sepsis-associated disseminated intravascular coagulation (DIC)

    Article • Scientific Reports, December 2023, Springer Science + Business Media

    Prof. Toshiaki Iba

  2. Defining heparin resistance: communication from the ISTH SSC Subcommittee of Perioperative and Critical Care Thrombosis and Hemostasis

    Article • Journal of Thrombosis and Haemostasis, December 2023, Elsevier

    Prof. Toshiaki Iba

  3. Mechanisms and management of the coagulopathy of trauma and sepsis: trauma-induced coagulopathy, sepsis-induced coagulopathy, and disseminated intravascular coagulation

    Article • Journal of Thrombosis and Haemostasis, December 2023, Elsevier

    Prof. Toshiaki Iba

  4. The antithrombin activity recovery after substitution therapy is associated with improved 28-day mortality in patients with sepsis-associated disseminated intravascular coagulation

    Article • Thrombosis Journal, November 2023, Springer Science + Business Media

    Prof. Toshiaki Iba

  5. Persistent and Late-Onset Disseminated Intravascular Coagulation Are Closely Related to Poor Prognosis in Patients with Sepsis

    Article • Thrombosis and Haemostasis, October 2023, Thieme Publishing Group

    Prof. Toshiaki Iba

  6. What Role Does Microthrombosis Play in Long COVID?

    Article • Seminars in Thrombosis and Hemostasis, September 2023, Thieme Publishing Group

    Prof. Toshiaki Iba

  7. A commentary on “Thromboinflammation in long COVID – the elusive key to post-infection sequelae?”

    Article • Journal of Thrombosis and Haemostasis, August 2023, Elsevier

    Prof. Toshiaki Iba

  8. Thromboinflammation in acute injury: infections, heatstroke, and trauma

    Article • Journal of Thrombosis and Haemostasis, August 2023, Elsevier

    Prof. Toshiaki Iba

  9. Super Formula for Diagnosing Disseminated Intravascular Coagulation Using Soluble C-Type Lectin-like Receptor 2

    Article • Diagnostics, July 2023, MDPI AG

    Prof. Toshiaki Iba

  10. What’s fishy about protamine? Clinical use, adverse reactions, and potential alternatives

    Article • Journal of Thrombosis and Haemostasis, July 2023, Elsevier

    Prof. Toshiaki Iba

  11. “Communication from the Scientific and Standardization Committee of the International Society on Thrombosis and Hemostasis on sepsis-induced coagulopathy in the management of sepsis”: reply

    Article • Journal of Thrombosis and Haemostasis, June 2023, Elsevier

    Prof. Toshiaki Iba

  12. The pathophysiology, diagnosis, and management of sepsis-associated disseminated intravascular coagulation

    Article • Journal of Intensive Care, May 2023, Springer Science + Business Media

    Prof. Toshiaki Iba

  13. Thrombotic Mechanism Involving Platelet Activation, Hypercoagulability and Hypofibrinolysis in Coronavirus Disease 2019

    Article • International Journal of Molecular Sciences, April 2023, MDPI AG

    Prof. Toshiaki Iba

  14. Communication from the Scientific Standardization Committees of the International Society on Thrombosis and Haemostasis on vascular endothelium-related biomarkers in disseminated intravascular coagulation

    Article • Journal of Thrombosis and Haemostasis, March 2023, Elsevier

    Prof. Toshiaki Iba

  15. Communication from the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis on sepsis-induced coagulopathy in the management of sepsis

    Article • Journal of Thrombosis and Haemostasis, January 2023, Elsevier

    Prof. Toshiaki Iba

  16. Designing the Diagnostic Criteria for Disseminated Intravascular Coagulation (DIC)

    Article • Juntendo Medical Journal, January 2023, The Jutendo Medical Journal

    Prof. Toshiaki Iba

  17. Disseminated Intravascular Coagulation: The Past, Present, and Future Considerations

    Article • Seminars in Thrombosis and Hemostasis, September 2022, Thieme Publishing Group

    Prof. Toshiaki Iba

  18. Intracellular communication and immunothrombosis in sepsis

    Article • Journal of Thrombosis and Haemostasis, August 2022, Wiley

    Prof. Toshiaki Iba

  19. Morphological Changes in Blood Cells in a Rat Model of Heatstroke: A Pilot Study

    Article • Journal of Clinical Medicine, August 2022, MDPI AG

    Prof. Toshiaki Iba

  20. ISTH guidelines for antithrombotic treatment in COVID ‐19

    Article • Journal of Thrombosis and Haemostasis, July 2022, Wiley

    Prof. Toshiaki Iba

  21. Thrombosis and thrombocytopenia in COVID-19 and after COVID-19 vaccination

    Article • Trends in Cardiovascular Medicine, July 2022, Elsevier

    Prof. Toshiaki Iba

  22. Elevated Plasma Soluble C-Type Lectin-like Receptor 2 Is Associated with the Worsening of Coronavirus Disease 2019

    Article • Journal of Clinical Medicine, February 2022, MDPI AG

    Prof. Toshiaki Iba

  23. Heatstroke-induced coagulopathy: Biomarkers, mechanistic insights, and patient management

    Article • EClinicalMedicine, February 2022, Elsevier

    Prof. Toshiaki Iba

  24. Nevertheless, the importance of coagulation abnormalities should be emphasized in international sepsis guidelines

    Article • Journal of Intensive Care, January 2022, Springer Science + Business Media

    Prof. Toshiaki Iba

  25. The roles of platelets in COVID-19-associated coagulopathy and vaccine-induced immune thrombotic thrombocytopenia

    Article • Trends in Cardiovascular Medicine, January 2022, Elsevier

    Prof. Toshiaki Iba

  26. Roles of Coagulation Abnormalities and Microthrombosis in Sepsis: Pathophysiology, Diagnosis, and Treatment

    Article • Archives of Medical Research, November 2021, Elsevier

    Prof. Toshiaki Iba

  27. Viral-Induced Inflammatory Coagulation Disorders: Preparing for Another Epidemic

    Article • Thrombosis and Haemostasis, July 2021, Thieme Publishing Group

    Prof. Toshiaki Iba

  28. COVID‐19: Thrombosis, thromboinflammation, and anticoagulation considerations

    Article • International Journal of Laboratory Hematology, July 2021, Wiley

    Prof. Toshiaki Iba

  29. Soluble C-Type Lectin-Like Receptor 2 Is a Biomarker for Disseminated Intravascular Coagulation

    Article • Journal of Clinical Medicine, June 2021, MDPI AG

    Prof. Toshiaki Iba

  30. Endothelial Injury in COVID-19 and Acute Infections

    Article • Arteriosclerosis Thrombosis and Vascular Biology, May 2021, Wolters Kluwer Health

    Prof. Toshiaki Iba

  31. Managing thrombosis and cardiovascular complications of COVID-19: answering the questions in COVID-19-associated coagulopathy

    Article • Expert Review of Respiratory Medicine, March 2021, Taylor & Francis

    Prof. Toshiaki Iba

  32. Diagnosis of Sepsis by AI-Aided Proteomics Using 2D Electrophoresis Images of Patient Serum Incorporating Transfer Learning for Deep Neural Networks

    Article • Applied Sciences, February 2021, MDPI AG

    Prof. Toshiaki Iba

  33. Ethnic differences in thromboprophylaxis for COVID-19 patients: should they be considered?

    Article • International Journal of Hematology, January 2021, Springer Science + Business Media

    Prof. Toshiaki Iba

  34. Proposal of the Definition for COVID-19-Associated Coagulopathy

    Article • Journal of Clinical Medicine, January 2021, MDPI AG

    Prof. Toshiaki Iba

  35. Recent advances in the research and management of sepsis-associated DIC

    Article • International Journal of Hematology, January 2021, Springer Science + Business Media

    Prof. Toshiaki Iba

  36. Editorial commentary: Vascular injury in acute infections and COVID-19: everything old is new again

    Article • Trends in Cardiovascular Medicine, January 2021, Elsevier

    Prof. Toshiaki Iba

  37. Newly Developed Recombinant Antithrombin Protects the Endothelial Glycocalyx in an Endotoxin-Induced Rat Model of Sepsis

    Article • International Journal of Molecular Sciences, December 2020, MDPI AG

    Prof. Toshiaki Iba

  38. COVID‐19 coagulopathy in pregnancy: Critical review, preliminary recommendations, and ISTH registry—Communication from the ISTH SSC for Women’s Health

    Article • Journal of Thrombosis and Haemostasis, October 2020, Wiley

    Prof. Toshiaki Iba

  39. The coagulopathy, endotheliopathy, and vasculitis of COVID-19

    Article • Inflammation Research, September 2020, Springer Science + Business Media

    Prof. Toshiaki Iba

  40. ISTH DIC subcommittee communication on anticoagulation in COVID‐19

    Article • Journal of Thrombosis and Haemostasis, August 2020, Wiley

    Prof. Toshiaki Iba

  41. Underlying disorders of disseminated intravascular coagulation: Communication from the ISTH SSC Subcommittees on Disseminated Intravascular Coagulation and Perioperative and Critical Care Thrombosis and Hemostasis

    Article • Journal of Thrombosis and Haemostasis, August 2020, Wiley

    Prof. Toshiaki Iba

  42. Coagulopathy in COVID‐19

    Article • Journal of Thrombosis and Haemostasis, July 2020, Wiley

    Prof. Toshiaki Iba

  43. The unique characteristics of COVID-19 coagulopathy

    Article • Critical Care, June 2020, Springer Science + Business Media

    Prof. Toshiaki Iba

  44. RE: The prothrombin time ratio is not a more effective marker for evaluating sepsis‐induced coagulopathy than fibrin‐related markers: Response to the Letter‐to‐the‐Editor by Dr Wada

    Article • Journal of Thrombosis and Haemostasis, June 2020, Wiley

    Prof. Toshiaki Iba

  45. Efficacy and safety of recombinant human soluble thrombomodulin in patients with sepsis‐associated coagulopathy: A systematic review and meta‐analysis

    Article • Journal of Thrombosis and Haemostasis, April 2020, Wiley

    Prof. Toshiaki Iba

  46. Diagnosis and management of sepsis‐induced coagulopathy and disseminated intravascular coagulation

    Article • Journal of Thrombosis and Haemostasis, August 2019, Wiley

    Prof. Toshiaki Iba

  47. The progression from coagulopathy to disseminated intravascular coagulation in representative underlying diseases

    Article • Thrombosis Research, July 2019, Elsevier

    Prof. Toshiaki Iba

  48. DIC in obstetrics: Diagnostic score, highlights in management, and international registry‐communication from the DIC and Women's Health SSCs of the International Society of Thrombosis and Haemostasis

    Article • Journal of Thrombosis and Haemostasis, June 2019, Wiley

    Prof. Toshiaki Iba

  49. Proposal of a two‐step process for the diagnosis of sepsis‐induced disseminated intravascular coagulation

    Article • Journal of Thrombosis and Haemostasis, June 2019, Wiley

    Prof. Toshiaki Iba

  50. Current status of venous thromboembolism development during the perioperative period for colorectal cancer, its prevention with enoxaparin, and monitoring methods

    Article • Therapeutics and Clinical Risk Management, June 2019, Dove Medical Press

    Dr Yuichi TOMIKI, Prof. Toshiaki Iba

  51. Sepsis-associated disseminated intravascular coagulation and its differential diagnoses

    Article • Journal of Intensive Care, May 2019, Springer Science + Business Media

    Prof. Toshiaki Iba

  52. The wind changed direction and the big river still flows: from EUPHRATES to TIGRIS

    Article • Journal of Intensive Care, May 2019, Springer Science + Business Media

    Prof. Toshiaki Iba

  53. Diagnosis of sepsis‐induced disseminated intravascular coagulation and coagulopathy

    Article • Acute Medicine & Surgery, April 2019, Wiley

    Prof. Toshiaki Iba

  54. Derangement of the endothelial glycocalyx in sepsis

    Article • Journal of Thrombosis and Haemostasis, February 2019, Wiley

    Prof. Toshiaki Iba

  55. Differential diagnoses for sepsis‐induced disseminated intravascular coagulation: communication from the SSC of the ISTH

    Article • Journal of Thrombosis and Haemostasis, January 2019, Wiley

    Prof. Toshiaki Iba

  56. Usefulness of Measuring Changes in SOFA Score for the Prediction of 28-Day Mortality in Patients With Sepsis-Associated Disseminated Intravascular Coagulation

    Article • Clinical and Applied Thrombosis/Hemostasis, January 2019, SAGE Publications

    Prof. Toshiaki Iba

  57. Oh, how hard it is to open the gate for sepsis trials: lessons from SCARLET

    Article • Acute Medicine & Surgery, November 2018, Wiley

    Prof. Toshiaki Iba

  58. Protection of the endothelial glycocalyx by antithrombin in an endotoxin-induced rat model of sepsis

    Article • Thrombosis Research, November 2018, Elsevier

    Prof. Toshiaki Iba

  59. Role of extracellular vesicles in the development of sepsis-induced coagulopathy

    Article • Journal of Intensive Care, October 2018, Springer Science + Business Media

    Prof. Toshiaki Iba

  60. Prediction of Early Death in Patients With Sepsis-Associated Coagulation Disorder Treated With Antithrombin Supplementation

    Article • Clinical and Applied Thrombosis/Hemostasis, September 2018, SAGE Publications

    Prof. Toshiaki Iba

  61. Newly Proposed Sepsis-Induced Coagulopathy Precedes International Society on Thrombosis and Haemostasis Overt-Disseminated Intravascular Coagulation and Predicts High Mortality

    Article • Journal of Intensive Care Medicine, May 2018, SAGE Publications

    Prof. Toshiaki Iba

  62. Sepsis-Induced Coagulopathy and Japanese Association for Acute Medicine DIC in Coagulopathic Patients with Decreased Antithrombin and Treated by Antithrombin

    Article • Clinical and Applied Thrombosis/Hemostasis, April 2018, SAGE Publications

    Prof. Toshiaki Iba

  63. Inflammation and thrombosis: roles of neutrophils, platelets and endothelial cells and their interactions in thrombus formation during sepsis

    Article • Journal of Thrombosis and Haemostasis, December 2017, Wiley

    Prof. Toshiaki Iba

  64. Modified DIC diagnostic criteria

    Article • Clinical and Applied Thrombosis/Hemostasis, July 2017, SAGE Publications

    Prof. Toshiaki Iba

  65. Efficacy and Bleeding Risk of Antithrombin Supplementation in Patients With Septic Disseminated Intravascular Coagulation: A Third Survey

    Article • Clinical and Applied Thrombosis/Hemostasis, May 2016, SAGE Publications

    Prof. Toshiaki Iba

  66. Physiological Levels of Pentraxin 3 and Albumin Attenuate Vascular Endothelial Cell Damage Induced by Histone H3In Vitro

    Article • Microcirculation, April 2016, Wiley

    Prof. Toshiaki Iba

  67. Prothrombin Time Tests for the Monitoring of Direct Oral Anticoagulants and Their Evaluation as Indicators of the Reversal Effect

    Article • Clinical and Applied Thrombosis/Hemostasis, March 2016, SAGE Publications

    Prof. Toshiaki Iba

  68. Antithrombin or thrombomodulin administration in severe pneumonia patients with sepsis and disseminated intravascular coagulation: comment on two papers

    Article • Journal of Thrombosis and Haemostasis, March 2015, Wiley

    Prof. Toshiaki Iba

  69. Combination of antithrombin and recombinant thrombomodulin modulates neutrophil cell-death and decreases circulating DAMPs levels in endotoxemic rats

    Article • Thrombosis Research, July 2014, Elsevier

    Prof. Toshiaki Iba, ISAO NAGAOKA

  70. Anticoagulant therapy for sepsis-associated disseminated intravascular coagulation: the view from Japan

    Article • Journal of Thrombosis and Haemostasis, June 2014, Wiley

    Prof. Toshiaki Iba

  71. Rivaroxaban attenuates leukocyte adhesion in the microvasculature and thrombus formation in an experimental mouse model of type 2 diabetes mellitus

    Article • Thrombosis Research, February 2014, Elsevier

    Prof. Toshiaki Iba

  72. Neutrophil extracellular traps, damage-associated molecular patterns, and cell death during sepsis

    Article • Acute Medicine & Surgery, November 2013, Wiley

    Prof. Toshiaki Iba

  73. The anticoagulant therapy for sepsis-associated disseminated intravascular coagulation

    Article • Thrombosis Research, May 2013, Elsevier

    Prof. Toshiaki Iba

  74. Recombinant thrombomodulin improves the visceral microcirculation by attenuating the leukocyte-endothelial interaction in a rat LPS model

    Article • Thrombosis Research, April 2013, Elsevier

    Prof. Toshiaki Iba