All Stories

  1. Replication Protein A helps protect the ends of chromosomes by activating telomerase.

    Article • PLoS Genetics, September 2026, PLOS

    Dr. Toru M Nakamura

  2. Comprehensive mutational analysis of the checkpoint signaling function of Rpa1/Ssb1 in fission yeast

    Article • PLoS Genetics, May 2023, PLOS

    Dr. Toru M Nakamura

  3. A tel2 Mutation That Destabilizes the Tel2-Tti1-Tti2 Complex Eliminates Rad3 ATR Kinase Signaling in the DNA Replication Checkpoint and Leads to Telomere ...

    Article • Molecular and Cellular Biology, October 2019, Taylor & Francis

    Dr. Toru M Nakamura

  4. Tpz1TPP1 prevents telomerase activation and protects telomeres by modulating the Stn1-Ten1 complex in fission yeast

    Article • Communications Biology, August 2019, Springer Science + Business Media

    Dr. Toru M Nakamura

  5. The NuA4 acetyltransferase and histone H4 acetylation promote replication recovery after topoisomerase I-poisoning

    Article • Epigenetics & Chromatin, April 2019, Springer Science + Business Media

    Dr. Toru M Nakamura

  6. The fission yeast Stn1-Ten1 complex limits telomerase activity via its SUMO-interacting motif and promotes telomeres replication

    Article • Science Advances, May 2018, American Association for the Advancement of Science

    Dr. Toru M Nakamura

  7. LARP7-like protein Pof8 regulates telomerase assembly and poly(A)+TERRA expression in fission yeast

    Article • Nature Communications, February 2018, Springer Science + Business Media

    Dr. Toru M Nakamura

  8. SUMO-targeted ubiquitin ligase activity can either suppress or promote genome instability, depending on the nature of the DNA lesion

    Article • PLoS Genetics, May 2017, PLOS

    Dr. Toru M Nakamura

  9. Swi1Timeless Prevents Repeat Instability at Fission Yeast Telomeres

    Article • PLoS Genetics, March 2016, PLOS

    Dr. Toru M Nakamura

  10. Ccq1-Tpz1TPP1interaction facilitates telomerase and SHREC association with telomeres in fission yeast

    Article • Molecular Biology of the Cell, November 2015, American Society for Cell Biology (ASCB)

    Dr. Toru M Nakamura

  11. RPA prevents G-rich structure formation at lagging-strand telomeres to allow maintenance of chromosome ends

    Article • The EMBO Journal, June 2015, EMBO

    vincent GELI, Dr. Toru M Nakamura

  12. Tpz1-Ccq1 and Tpz1-Poz1 Interactions within Fission Yeast Shelterin Modulate Ccq1 Thr93 Phosphorylation and Telomerase Recruitment

    Article • PLoS Genetics, October 2014, PLOS

    Dr. Toru M Nakamura

  13. SUMOylation regulates telomere length by targeting the shelterin subunit Tpz1 Tpp1 to modulate shelterin–Stn1 interaction in fission yeast

    Article • Proceedings of the National Academy of Sciences, April 2014, Proceedings of the National Academy of Sciences

    Dr. Toru M Nakamura

  14. Telomere Regulation During the Cell Cycle in Fission Yeast

    Article • January 2014, Springer Science + Business Media

    Dr. Toru M Nakamura

  15. Fission Yeast Shelterin Regulates DNA Polymerases and Rad3ATR Kinase to Limit Telomere Extension

    Article • PLoS Genetics, November 2013, PLOS

    Dr. Toru M Nakamura

  16. The Double-Bromodomain Proteins Bdf1 and Bdf2 Modulate Chromatin Structure to Regulate S-Phase Stress Response in Schizosaccharomyces pombe

    Article • Genetics, February 2012, Oxford University Press (OUP)

    Dr. Toru M Nakamura

  17. Tel1ATM and Rad3ATR kinases promote Ccq1-Est1 interaction to maintain telomeres in fission yeast

    Article • Nature Structural & Molecular Biology, November 2011, Springer Science + Business Media

    Dr. Toru M Nakamura

  18. Telomeres avoid end detection by severing the checkpoint signal transduction pathway

    Article • Nature, September 2010, Springer Science + Business Media

    Dr. Toru M Nakamura

  19. HAATI survivors replace canonical telomeres with blocks of generic heterochromatin

    Article • Nature, September 2010, Springer Science + Business Media

    Dr. Toru M Nakamura

  20. Roles of the checkpoint sensor clamp Rad9-Rad1-Hus1 (911)-complex and the clamp loaders Rad17-RFC and Ctf18-RFC inSchizosaccharomyces pombetelomere maintenance

    Article • Cell Cycle, June 2010, Taylor & Francis

    Dr. Toru M Nakamura

  21. A Kinase-Independent Role for the Rad3ATR-Rad26ATRIP Complex in Recruitment of Tel1ATM to Telomeres in Fission Yeast

    Article • PLoS Genetics, February 2010, PLOS

    Dr. Toru M Nakamura

  22. Roles of Heterochromatin and Telomere Proteins in Regulation of Fission Yeast Telomere Recombination and Telomerase Recruitment

    Article • Journal of Biological Chemistry, February 2010, Elsevier

    Dr. Toru M Nakamura

  23. To fuse or not to fuse: how do checkpoint and DNA repair proteins maintain telomeres?

    Article • Frontiers in Bioscience, January 2010, IMR Press

    Dr. Toru M Nakamura

  24. Protection and replication of telomeres in fission yeastThis paper is one of a selection of papers published in this Special Issue, entitled 30th Annual International Asilomar Chromatin and Chromosomes Conference, and has undergone the Journal’s usual ...

    Article • Biochemistry and Cell Biology, October 2009, Canadian Science Publishing

    Dr. Toru M Nakamura

  25. Fission Yeast Tel1ATM and Rad3ATR Promote Telomere Protection and Telomerase Recruitment

    Article • PLoS Genetics, August 2009, PLOS

    Dr. Toru M Nakamura

  26. Differential arrival of leading and lagging strand DNA polymerases at fission yeast telomeres

    Article • The EMBO Journal, February 2009, Springer Science + Business Media

    Dr. Toru M Nakamura

  27. RFCCtf18and the Swi1-Swi3 Complex Function in Separate and Redundant Pathways Required for the Stabilization of Replication Forks to Facilitate Sister Chromatid Cohesion inSchizosaccharomyces pombe

    Article • Molecular Biology of the Cell, February 2008, American Society for Cell Biology (ASCB)

    Dr. Toru M Nakamura

  28. Recombination-Based Telomere Maintenance Is Dependent on Tel1-MRN and Rap1 and Inhibited by Telomerase, Taz1, and Ku in Fission Yeast

    Article • Molecular and Cellular Biology, December 2007, ASM Journals

    Dr. Toru M Nakamura

  29. Histone modification-dependent and -independent pathways for recruitment of checkpoint protein Crb2 to double-strand breaks

    Article • Genes & Development, June 2006, Cold Spring Harbor Laboratory Press

    Dr. Toru M Nakamura

  30. Rad22Rad52-dependent Repair of Ribosomal DNA Repeats Cleaved by Slx1-Slx4 Endonuclease

    Article • Molecular Biology of the Cell, April 2006, American Society for Cell Biology (ASCB)

    Dr. Toru M Nakamura

  31. Cooperative Control of Crb2 by ATM Family and Cdc2 Kinases Is Essential for the DNA Damage Checkpoint in Fission Yeast

    Article • Molecular and Cellular Biology, December 2005, ASM Journals

    Dr. Toru M Nakamura

  32. Histone H2A Phosphorylation Controls Crb2 Recruitment at DNA Breaks, Maintains Checkpoint Arrest, and Influences DNA Repair in Fission Yeast

    Article • Molecular and Cellular Biology, September 2004, ASM Journals

    Dr. Toru M Nakamura

  33. Histone H2A Phosphorylation Controls Crb2 Recruitment at DNA Breaks, Maintains Checkpoint Arrest, and Influences DNA Repair in Fission Yeast

    Article • Molecular and Cellular Biology, July 2004, ASM Journals

    Dr. Toru M Nakamura

  34. The Fission Yeast Rad32 (Mre11)-Rad50-Nbs1 Complex Is Required for the S-Phase DNA Damage Checkpoint

    Article • Molecular and Cellular Biology, September 2003, ASM Journals

    Dr. Toru M Nakamura

  35. Retention but Not Recruitment of Crb2 at Double-Strand Breaks Requires Rad1 and Rad3 Complexes

    Article • Molecular and Cellular Biology, September 2003, ASM Journals

    Dr. Toru M Nakamura

  36. Telomere Binding of Checkpoint Sensor and DNA Repair Proteins Contributes to Maintenance of Functional Fission Yeast Telomeres

    Article • Genetics, August 2002, Oxford University Press (OUP)

    Dr. Toru M Nakamura

  37. Analysis of telomerase catalytic subunit mutants in vivo and in vitro in Schizosaccharomyces pombe

    Article • Proceedings of the National Academy of Sciences, May 2000, Proceedings of the National Academy of Sciences

    Dr. Toru M Nakamura

  38. Two Modes of Survival of Fission Yeast Without Telomerase

    Article • Science, October 1998, American Association for the Advancement of Science

    Dr. Toru M Nakamura

  39. Reversing Time: Origin of Telomerase

    Article • Cell, March 1998, Elsevier

    Dr. Toru M Nakamura

  40. Telomerase Catalytic Subunit Homologs from Fission Yeast and Human

    Article • Science, August 1997, American Association for the Advancement of Science

    Dr. Toru M Nakamura

  41. Relative orientation of RNA helices in a group 1 ribozyme determined by helix extension electron microscopy.

    Article • The EMBO Journal, October 1995, Springer Science + Business Media

    Dr. Toru M Nakamura