All Stories

  1. Is intramuscular adrenaline used promptly against drug-induced anaphylaxis? A perspective from recent analyses of fatal cases in Japan

    Article • Allergology International, April 2026, Elsevier

    Dr Tomonori Takazawa

  2. Analysis of perioperative antibiotic usage in the operating room during the 2019 cefazolin shortage in Japan: a multicenter observational study

    Article • Journal of Anesthesia, March 2026, Springer Science + Business Media

    Dr Tomonori Takazawa

  3. Environmental enrichment enhances anesthetic actions in rat amygdala hippocampal circuits in vitro

    Article • Frontiers in Pharmacology, December 2025, Frontiers

    Dr Tomonori Takazawa

  4. Perioperative anaphylaxis in Japan: Epidemiology, diagnosis, and challenges

    Article • Allergology International, December 2025, Elsevier

    Dr Tomonori Takazawa

  5. Beyond a hasty ban: a call for a nuanced approach to desflurane use in Japanese anesthesia practice

    Article • Journal of Anesthesia, November 2025, Springer Science + Business Media

    Dr Tomonori Takazawa

  6. Posterior reversible encephalopathy syndrome during epidural labor analgesia: a case report

    Article • JA Clinical Reports, August 2025, Springer Science + Business Media

    Dr Tomonori Takazawa

  7. Effects of a kappa opioid receptor antagonist on delayed postoperative pain recovery in a novel mouse sleep disorder model

    Article • Frontiers in Pain Research, July 2025, Frontiers

    Dr Tomonori Takazawa

  8. Association between epidural catheter tip malposition and anesthesiologists’ experience after graduation: A cross-sectional study using postoperative CT images

    Article • PLOS One, June 2025, PLOS

    Dr Tomonori Takazawa

  9. Cerebral gas embolism in a patient without right-to-left shunt after robotic partial nephrectomy

    Article • JA Clinical Reports, May 2025, Springer Science + Business Media

    Dr Tomonori Takazawa

  10. Historical Review of Perioperative Anaphylaxis in Japan

    Article • The Kitakanto Medical Journal, February 2025, Kitakanto Medical Society

    Dr Tomonori Takazawa

  11. Comparison of the diagnostic performance of tryptase and histamine for perioperative anaphylaxis: A multicenter prospective study

    Article • Allergology International, October 2024, Elsevier

    Dr Tomonori Takazawa

  12. Investigation of the optimal method of oxygen administration with simultaneous use of a surgical mask in postoperative patients: a randomized cross-over study

    Article • JA Clinical Reports, September 2024, Springer Science + Business Media

    Dr Tomonori Takazawa

  13. Comment on: “Treatment-resistant hiccups during general anesthesia possibly caused by remimazolam: a case report”—a reply

    Article • JA Clinical Reports, September 2024, Springer Science + Business Media

    Dr Tomonori Takazawa

  14. Treatment-resistant hiccups during general anesthesia possibly caused by remimazolam: a case report

    Article • JA Clinical Reports, May 2024, Springer Science + Business Media

    Dr Tomonori Takazawa

  15. Anesthesia management of laparoscopic right colectomy in an older patient with postoperative tetralogy of Fallot with residual anomaly

    Article • JA Clinical Reports, April 2024, Springer Science + Business Media

    Dr Tomonori Takazawa

  16. Perioperative anaphylaxis with no identifiable cause

    Article • JA Clinical Reports, January 2024, Springer Science + Business Media

    Dr Tomonori Takazawa

  17. The Japanese Epidemiologic Study for Perioperative Anaphylaxis, a prospective nationwide study: allergen exposure, epidemiology, and diagnosis of anaphylaxis during general anaesthesia

    Article • British Journal of Anaesthesia, July 2023, Elsevier

    Dr Tomonori Takazawa

  18. The Japanese Epidemiologic Study for Perioperative Anaphylaxis, a prospective nationwide study: clinical signs, severity, and therapeutic agents

    Article • British Journal of Anaesthesia, July 2023, Elsevier

    Dr Tomonori Takazawa

  19. Sustainable development goals for Japanese anesthesiologists: how to survive in times of turmoil

    Article • Journal of Anesthesia, June 2023, Springer Science + Business Media

    Dr Tomonori Takazawa

  20. Investigating the optimal diagnostic value of histamine for diagnosing perioperative hypersensitivity: a prospective, observational study

    Article • Journal of Anesthesia, May 2023, Springer Science + Business Media

    Dr Tomonori Takazawa

  21. Life-threatening chlorhexidine anaphylaxis caused by skin preparation before chlorhexidine-free central venous catheter insertion: a case report and literature review

    Article • Journal of Anesthesia, April 2023, Springer Science + Business Media

    Dr Tomonori Takazawa

  22. Long-Term Prognosis Following Early Rehabilitation in the ICU: A Retrospective Cohort Study

    Article • Critical Care Medicine, March 2023, Wolters Kluwer Health

    Dr Tomonori Takazawa

  23. Prevention of Postoperative Cognitive Dysfunction by Minocycline in Elderly Patients after Total Knee Arthroplasty: A Randomized, Double-blind, Placebo-controlled Clinical Trial

    Article • Anesthesiology, December 2022, Wolters Kluwer Health

    Professor Kunihiko Hayashi, Dr Tomonori Takazawa

  24. Intraoperative chlorhexidine-induced anaphylaxis suggesting an immunoglobulin-E-dependent mechanism indicated by basophil activation tests: two case reports

    Article • JA Clinical Reports, November 2022, Springer Science + Business Media

    Dr Tomonori Takazawa

  25. Risk factors for mechanical ventilation and ECMO in COVID-19 patients admitted to the ICU: A multicenter retrospective observational study

    Article • PLOS One, November 2022, PLOS

    Dr Tomonori Takazawa

  26. Local anesthetic lidocaine induces growth suppression of HeLa cells by decreasing and changing the cellular localization of the proliferation marker Ki‐67

    Article • Genes to Cells, September 2022, Wiley

    Dr Tomonori Takazawa

  27. Local anesthetic lidocaine-inducible gene, growth differentiation factor-15 suppresses the growth of cancer cell lines

    Article • Scientific Reports, August 2022, Springer Science + Business Media

    Dr Tomonori Takazawa

  28. Practical guidelines for the response to perioperative anaphylaxis

    Article • Journal of Anesthesia, October 2021, Springer Science + Business Media

    Dr Tomonori Takazawa

  29. Intraoperative anaphylaxis due to aprotinin after local application of fibrin sealant diagnosed by skin tests and basophil activation tests: a case report

    Article • JA Clinical Reports, September 2021, Springer Science + Business Media

    Dr Tomonori Takazawa

  30. Investigation of the optimal method of oxygen administration with simultaneous use of a surgical mask: a randomized control study

    Article • Journal of Anesthesia, September 2021, Springer Science + Business Media

    Dr Tomonori Takazawa

  31. Impact of the First Wave of COVID-19 on the Number of General Anesthesia Cases in 34 Tertiary Hospitals in Japan: A Multicenter Retrospective Study

    Article • Anesthesiology Research and Practice, August 2021, Hindawi Publishing Corporation

    Dr Tomonori Takazawa

  32. Interpretation of concurrent positive skin tests to prophylactic antibiotics and rocuronium

    Article • JA Clinical Reports, August 2021, Springer Science + Business Media

    Dr Tomonori Takazawa

  33. Reply to the letter

    Article • Journal of Anesthesia, July 2021, Springer Science + Business Media

    Dr Tomonori Takazawa

  34. Possible immunoglobulin-E-dependent sugammadex-induced anaphylaxis caused by an epitope other than γ-cyclodextrin: a case report

    Article • Journal of Medical Case Reports, June 2021, Springer Science + Business Media

    Dr Tomonori Takazawa

  35. Remimazolam anaphylaxis during anesthesia induction

    Article • Journal of Anesthesia, May 2021, Springer Science + Business Media

    Dr Tomonori Takazawa

  36. Does a surgical mask improve oxygenation in COVID-19 patients?

    Article • JA Clinical Reports, April 2021, Springer Science + Business Media

    Dr Tomonori Takazawa

  37. Drug-induced anaphylaxis during general anesthesia in 14 tertiary hospitals in Japan: a retrospective, multicenter, observational study

    Article • Journal of Anesthesia, January 2021, Springer Science + Business Media

    Dr Tomonori Takazawa

  38. COVID-19 with repeated positive test results for SARS-CoV-2 by PCR and then negative test results twice during intensive care: a case report

    Article • Journal of Medical Case Reports, October 2020, Springer Science + Business Media

    Dr Tomonori Takazawa

  39. Improvement of Severe COVID-19 in an Elderly Man by Sequential Use of Antiviral Drugs

    Article • Case Reports in Infectious Diseases, September 2020, Hindawi Publishing Corporation

    Dr Tomonori Takazawa

  40. History of the development of antagonists for neuromuscular blocking agents

    Article • Journal of Anesthesia, August 2020, Springer Science + Business Media

    Dr Tomonori Takazawa

  41. Normalized skin conductance level could differentiate physical pain stimuli from other sympathetic stimuli

    Article • Scientific Reports, July 2020, Springer Science + Business Media

    Dr Tomonori Takazawa

  42. Does sugammadex have multiple mechanisms for causing anaphylaxis?

    Article • The Journal of Allergy and Clinical Immunology In Practice, July 2020, Elsevier

    Dr Tomonori Takazawa

  43. Interpreting the results of early skin tests after perioperative anaphylaxis requires special attention: a case report and review of literature

    Article • Journal of Anesthesia, May 2020, Springer Science + Business Media

    Dr Tomonori Takazawa

  44. Development of Artificial Skin Using Keratin Film for Evaluation of Puncture Performance of Microneedle

    Article • Journal of Robotics and Mechatronics, April 2020, Fuji Technology Press Ltd.

    Dr Tomonori Takazawa

  45. Anaphylaxis caused by butylscopolamine bromide: a case report

    Article • JA Clinical Reports, April 2020, Springer Science + Business Media

    Dr Tomonori Takazawa

  46. A novel prediction equation of resting energy expenditure for Japanese septic patients

    Article • Journal of Critical Care, April 2020, Elsevier

    Dr Tomonori Takazawa

  47. Hemodynamically adjusted infrahepatic inferior venous cava clamping can reduce postoperative deterioration in renal function: a retrospective observational study

    Article • Journal of Anesthesia, February 2020, Springer Science + Business Media

    Dr Tomonori Takazawa

  48. Comparison of incidence of anaphylaxis between sugammadex and neostigmine: a retrospective multicentre observational study

    Article • British Journal of Anaesthesia, February 2020, Elsevier

    Dr Tomonori Takazawa

  49. A Puncturing Device that Mimics the Mechanism of Mosquito’s Proboscis and Labium - Verification of the Effect of Skin Deformation / Needle Buckling Prevention Mechanism and Puncture Experiment on Artificial Skin and Experimental Animals –

    Article • International Journal of Automation Technology, January 2020, Fuji Technology Press Ltd.

    Dr Tomonori Takazawa

  50. Mepivacaine-induced anaphylactic shock in a pregnant woman undergoing combined spinal and epidural anesthesia for cesarean delivery: a case report

    Article • JA Clinical Reports, December 2019, Springer Science + Business Media

    Dr Tomonori Takazawa

  51. Is it just a cefazolin issue?

    Article • JA Clinical Reports, September 2019, Springer Science + Business Media

    Dr Tomonori Takazawa

  52. Comparative epidemiology of suspected perioperative hypersensitivity reactions

    Article • British Journal of Anaesthesia, July 2019, Elsevier

    Dr Tomonori Takazawa

  53. Consensus clinical scoring for suspected perioperative immediate hypersensitivity reactions

    Article • British Journal of Anaesthesia, July 2019, Elsevier

    Dr Tomonori Takazawa

  54. In vitro diagnostic tests for perioperative hypersensitivity, a narrative review: potential, limitations, and perspectives

    Article • British Journal of Anaesthesia, July 2019, Elsevier

    Dr Tomonori Takazawa

  55. Management of a surgical patient with a label of penicillin allergy: narrative review and consensus recommendations

    Article • British Journal of Anaesthesia, July 2019, Elsevier

    Dr Tomonori Takazawa

  56. Management of suspected immediate perioperative allergic reactions: an international overview and consensus recommendations

    Article • British Journal of Anaesthesia, July 2019, Elsevier

    Dr Tomonori Takazawa

  57. The use of drug provocation testing in the investigation of suspected immediate perioperative allergic reactions: current status

    Article • British Journal of Anaesthesia, July 2019, Elsevier

    Dr Tomonori Takazawa

  58. Physiological and Pharmaceutical Knowledge in “Ninja” Society: Suggestions for Modern Anesthesiologists and Intensivists

    Article • Journal of Anesthesia History, October 2018, Elsevier

    Dr Tomonori Takazawa

  59. Required cefazolin concentration to maximize diagnostic accuracy of the basophil activation test for cefazolin-induced anaphylaxis

    Article • Journal of Anesthesia, September 2018, Springer Science + Business Media

    Dr Tomonori Takazawa

  60. Usefulness of Basophil Activation Tests for Diagnosis of Sugammadex-Induced Anaphylaxis

    Article • Anesthesia & Analgesia, May 2018, Wolters Kluwer Health

    Dr Tomonori Takazawa

  61. Is sugammadex alone sufficient to cause anaphylaxis?

    Article • Journal of Anesthesia, January 2018, Springer Science + Business Media

    Dr Tomonori Takazawa

  62. Cardiorespiratory dynamics of rescuers during cardiopulmonary resuscitation in a hypoxic environment

    Article • The American Journal of Emergency Medicine, January 2018, Elsevier

    Dr Tomonori Takazawa

  63. A device integrating microneedle and jig of preventing needle buckling/skin deformation inspired by mosquito — 3D fabrication and experiment of skin puncture/blood sampling

    Article • January 2018, Institute of Electrical & Electronics Engineers (IEEE)

    Dr Tomonori Takazawa

  64. Is use of glycine-containing drugs in anesthesia safe?

    Article • Journal of Anesthesia, October 2017, Springer Science + Business Media

    Dr Tomonori Takazawa

  65. Drug-induced anaphylaxis in the emergency room

    Article • Acute Medicine & Surgery, May 2017, Wiley

    Dr Tomonori Takazawa

  66. Inhibition Mediated by Glycinergic and GABAergic Receptors on Excitatory Neurons in Mouse Superficial Dorsal Horn Is Location-Specific but Modified by Inflammation

    Article • Journal of Neuroscience, January 2017, Society for Neuroscience

    Dr Tomonori Takazawa

  67. Present Clinical Status of Postoperative Cognitive Dysfunction Following Noncardiac Surgery

    Article • January 2017, Springer Science + Business Media

    Dr Tomonori Takazawa

  68. Simultaneous peripheral and central venous pressure monitoring for evaluating cardiac preload in critically ill patients

    Article • Biomedical Research and Clinical Practice, January 2017, Open Access Text Pvt, Ltd.

    Dr Tomonori Takazawa

  69. Epidemiology of perioperative anaphylaxis

    Article • La Presse Médicale, September 2016, Elsevier

    Dr Tomonori Takazawa

  70. A case of acute onset postoperative gas gangrene caused by Clostridium perfringens

    Article • BMC Research Notes, August 2016, Springer Science + Business Media

    Dr Tomonori Takazawa

  71. Comparison between resting energy expenditure measured by indirect calorimetry and metabolic rate estimate based on Harris-Benedict equation in septic patients

    Article • Biomedical Research and Clinical Practice, January 2016, Open Access Text Pvt, Ltd.

    Dr Tomonori Takazawa

  72. Sugammadex and rocuronium-induced anaphylaxis

    Article • Journal of Anesthesia, December 2015, Springer Science + Business Media

    Dr Tomonori Takazawa

  73. Paradoxical heart rate decrease after ephedrine injection during cesarean section under spinal anesthesia

    Article • British Journal of Anaesthesia, October 2015, Elsevier

    Dr Tomonori Takazawa

  74. Changes in intraocular pressure during surgery in the lateral decubitus position under sevoflurane and propofol anesthesia

    Article • Journal of Clinical Monitoring and Computing, October 2015, Springer Science + Business Media

    Dr Tomonori Takazawa

  75. Comparison between succinylcholine and rocuronium as neuromuscular blocking agents for electroconvulsive therapy in a patient with pseudocholinesterase deficiency

    Article • JA Clinical Reports, August 2015, Springer Science + Business Media

    Dr Tomonori Takazawa

  76. Flow cytometric investigation of sugammadex-induced anaphylaxis

    Article • British Journal of Anaesthesia, May 2015, Elsevier

    Dr Tomonori Takazawa

  77. Flow cytometric investigation of sugammadex-induced anaphylaxis

    Article • British Journal of Anaesthesia, February 2015, Elsevier

    Dr Tomonori Takazawa

  78. Anesthesia for Posterior Fossa Tumor Surgery

    Article • January 2015, Springer Science + Business Media

    Dr Tomonori Takazawa

  79. The Endocannabinoid, 2-Arachidonoyl Glycerol, Induces Growth Cone Collapse and Neurite Retraction in Growing Peripheral Sensory Neurons

    Article • World Journal of Neuroscience, January 2015, Scientific Research Publishing, Inc,

    Dr Tomonori Takazawa

  80. Three suspected cases of sugammadex-induced anaphylactic shock

    Article • BMC Anesthesiology, October 2014, Springer Science + Business Media

    Dr Tomonori Takazawa

  81. Pre- and postsynaptic inhibitory control in the spinal cord dorsal horn

    Article • Annals of the New York Academy of Sciences, March 2013, Wiley

    Dr Tomonori Takazawa

  82. Changes in Cerebral Oxygenation Assessed by Near-infrared Spectroscopy during Shoulder Arthroscopy in the Beach Chair Position after Brachial Plexus Block

    Article • Journal of Anesthesia & Clinical Research, January 2013, OMICS Publishing Group

    Dr Tomonori Takazawa

  83. Balance of older trekkers: data on alpine accidents and performance as assessed using a video game machine

    Article • The American Journal of Emergency Medicine, September 2012, Elsevier

    Dr Tomonori Takazawa

  84. Maturation of Spinal Motor Neurons Derived from Human Embryonic Stem Cells

    Article • PLOS One, July 2012, PLOS

    Dr Tomonori Takazawa

  85. Glycinergic and GABAergic tonic inhibition fine tune inhibitory control in regionally distinct subpopulations of dorsal horn neurons

    Article • The Journal of Physiology, July 2010, Wiley

    Dr Tomonori Takazawa

  86. Synaptic pathways and inhibitory gates in the spinal cord dorsal horn

    Article • Annals of the New York Academy of Sciences, June 2010, Wiley

    Dr Tomonori Takazawa

  87. Actions of propofol on substantia gelatinosa neurones in rat spinal cord revealed byin vitroandin vivopatch-clamp recordings

    Article • European Journal of Neuroscience, February 2009, Wiley

    Dr Tomonori Takazawa

  88. Relationship between afterhyperpolarization profiles and the regularity of spontaneous firings in rat medial vestibular nucleus neurons

    Article • European Journal of Neuroscience, July 2008, Wiley

    Dr Tomonori Takazawa

  89. Effects of spinal anesthesia on the peripheral and deep core temperature in elderly diabetic patients undergoing urological surgery

    Article • Journal of Anesthesia, August 2007, Springer Science + Business Media

    Dr Tomonori Takazawa

  90. The interaction of noradrenaline with sevoflurane on GABA(A) receptor-mediated inhibitory postsynaptic currents in the rat hippocampus

    Article • Brain Research, March 2005, Elsevier

    Dr Tomonori Takazawa

  91. Membrane and Firing Properties of Glutamatergic and GABAergic Neurons in the Rat Medial Vestibular Nucleus

    Article • Journal of Neurophysiology, November 2004, American Physiological Society

    Dr Tomonori Takazawa

  92. Experimental use of a transportable hyperbaric chamber durable for 15 psi at 3700 meters above sea level

    Article • Wilderness and Environmental Medicine, March 2000, Elsevier

    Dr Tomonori Takazawa

  93. Exercise-Induced Cerebral Deoxygenation among Untrained Trekkers at Moderate Altitudes

    Article • Archives of Environmental Health An International Journal, July 1999, Taylor & Francis

    Dr Tomonori Takazawa