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  1. MicroRNA-33 inhibition ameliorates muscular dystrophy by enhancing skeletal muscle regeneration

    Article • EMBO Molecular Medicine, July 2025, Springer Science + Business Media

    Dr Tomohide Takaya

  2. Osteogenic CpG Oligodeoxynucleotide, iSN40, Inhibits Osteoclastogenesis in a TLR9-Dependent Manner

    Article • Life, November 2024, MDPI AG

    Dr Tomohide Takaya

  3. Osteogenic CpG Oligodeoxynucleotide, iSN40, Inhibits Osteo-clastogenesis in a TLR9-Dependent Manner

    Article • September 2024, Cold Spring Harbor Laboratory Press

    Dr Tomohide Takaya

  4. Myogenic Anti-Nucleolin Aptamer iSN04 Inhibits Proliferation and Promotes Differentiation of Vascular Smooth Muscle Cells

    Article • Biomolecules, June 2024, MDPI AG

    Dr Tomohide Takaya

  5. Development of the 12-Base Short Dimeric Myogenetic Oligodeoxynucleotide That Induces Myogenic Differentiation

    Article • BioTech, April 2024, MDPI AG

    Dr Tomohide Takaya

  6. Myogenic Anti-Nucleolin Aptamer iSN04 Inhibits Proliferation and Promotes Differentiation of Vascular Smooth Muscle Cells

    Article • April 2024, Cold Spring Harbor Laboratory Press

    Dr Tomohide Takaya

  7. Development of the 12-Base Short Dimeric Myogenetic Oli-godeoxynucleotide That Induces Myogenic Differentiation

    Article • March 2024, Cold Spring Harbor Laboratory Press

    Dr Tomohide Takaya

  8. Myogenetic Oligodeoxynucleotide Induces Myocardial Differentiation of Murine Pluripotent Stem Cells

    Article • International Journal of Molecular Sciences, September 2023, MDPI AG

    Dr Tomohide Takaya

  9. Myogenetic Oligodeoxynucleotide Induces Myocardial Differentiation of Murine Pluripotent Stem Cells

    Article • August 2023, Cold Spring Harbor Laboratory Press

    Dr Tomohide Takaya

  10. Anti-nucleolin aptamer, iSN04, inhibits the inflammatory responses in C2C12 myoblasts by modulating the β-catenin/NF-κB signaling pathway

    Article • Biochemical and Biophysical Research Communications, July 2023, Elsevier

    Dr Tomohide Takaya

  11. Anti-nucleolin aptamer, iSN04, inhibits the inflammatory responses in myoblasts by modulating the β-catenin/NF-κB signaling pathway

    Article • April 2023, Cold Spring Harbor Laboratory Press

    Dr Tomohide Takaya

  12. Myogenetic Oligodeoxynucleotides as Anti-Nucleolin Aptamers Inhibit the Growth of Embryonal Rhabdomyosarcoma Cells

    Article • Biomedicines, October 2022, MDPI AG

    Dr Tomohide Takaya

  13. Myogenetic Oligodeoxynucleotide Restores Differentiation and Reverses Inflammation of Myoblasts Aggravated by Cancer-Conditioned Medium

    Article • Muscles, September 2022, MDPI AG

    Dr Tomohide Takaya

  14. Identification of a Novel Osteogenetic Oligodeoxynucleotide (osteoDN) That Promotes Osteoblast Differentiation in a TLR9-Independent Manner

    Article • Nanomaterials, May 2022, MDPI AG

    Dr Tomohide Takaya

  15. Identification of a Novel Osteogenetic Oligodeoxynucleotide (osteoDN) that Promotes Osteoblast Differentiation in a TLR9-Independent Manner

    Article • March 2022, Cold Spring Harbor Laboratory Press

    Dr Tomohide Takaya

  16. Three-dimensional structural analysis of mitochondria composing each subtype of fast-twitch muscle fibers in chicken

    Article • Journal of Veterinary Medical Science, January 2022, Japanese Society of Veterinary Science

    Dr Tomohide Takaya

  17. Myogenetic oligodeoxynucleotide restores differentiation and reverses inflammation of myoblasts aggravated by cancer-conditioned medium

    Article • November 2021, Cold Spring Harbor Laboratory Press

    Dr Tomohide Takaya

  18. Myogenetic oligodeoxynucleotides as anti-nucleolin aptamers inhibit the growth of embryonal rhabdomyosarcoma cells

    Article • October 2021, Cold Spring Harbor Laboratory Press

    Dr Tomohide Takaya

  19. Myogenetic Oligodeoxynucleotide (myoDN) Recovers the Differentiation of Skeletal Muscle Myoblasts Deteriorated by Diabetes Mellitus

    Article • Frontiers in Physiology, May 2021, Frontiers

    Dr Tomohide Takaya

  20. Myogenetic oligodeoxynucleotide (myoDN) recovers the differentiation of skeletal muscle myoblasts deteriorated by diabetes mellitus

    Article • March 2021, Cold Spring Harbor Laboratory Press

    Dr Tomohide Takaya

  21. Identification of the Myogenetic Oligodeoxynucleotides (myoDNs) That Promote Differentiation of Skeletal Muscle Myoblasts by Targeting Nucleolin

    Article • Frontiers in Cell and Developmental Biology, January 2021, Frontiers

    Dr Tomohide Takaya

  22. Myogenetic oligodeoxynucleotide complexed with berberine promotes differentiation of chicken myoblasts

    Article • Animal Science Journal, January 2021, Wiley

    Dr Tomohide Takaya

  23. Transcription of Endogenous Retrovirus Group K Members and Their Neighboring Genes in Chicken Skeletal Muscle Myoblasts

    Article • The Journal of Poultry Science, January 2021, Japan Poultry Science Association

    Dr Tomohide Takaya

  24. Myogenetic oligodeoxynucleotide (myoDN) complexed with berberine promotes differentiation of chicken skeletal muscle myoblasts

    Article • December 2020, Cold Spring Harbor Laboratory Press

    Dr Tomohide Takaya

  25. Identification of the myogenetic oligodeoxynucleotides (myoDNs) that promote differentiation of skeletal muscle myoblasts by targeting nucleolin

    Article • October 2020, Cold Spring Harbor Laboratory Press

    Dr Tomohide Takaya

  26. Physiological and Pathological Mitochondrial Clearance Is Related to Pectoralis Major Muscle Pathogenesis in Broilers With Wooden Breast Syndrome

    Article • Frontiers in Physiology, June 2020, Frontiers

    Dr Tomohide Takaya

  27. Distinct cell proliferation, myogenic differentiation, and gene expression in skeletal muscle myoblasts of layer and broiler chickens

    Article • Scientific Reports, November 2019, Springer Science + Business Media

    Dr Tomohide Takaya

  28. Berberine and palmatine inhibit the growth of human rhabdomyosarcoma cells

    Article • Bioscience Biotechnology and Biochemistry, August 2019, Taylor & Francis

    Dr Tomohide Takaya

  29. Toll-like receptor ligand-dependent inflammatory responses in chick skeletal muscle myoblasts

    Article • Developmental & Comparative Immunology, February 2019, Elsevier

    Dr Tomohide Takaya

  30. Theophylline suppresses interleukin-6 expression by inhibiting glucocorticoid receptor signaling in pre-adipocytes

    Article • Archives of Biochemistry and Biophysics, May 2018, Elsevier

    Dr Tomohide Takaya, Naoki Harada

  31. Autonomous xenogenic cell fusion of murine and chick skeletal muscle myoblasts

    Article • Animal Science Journal, August 2017, Wiley

    Professor Hiroshi Kagami, Dr Tomohide Takaya

  32. Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Plays an Important Role in Vascular Inflammation in Current Smokers

    Article • Journal of Atherosclerosis and Thrombosis, January 2013, Japan Atherosclerosis Society

    Dr Tomohide Takaya

  33. Highly Purified Eicosapentaenoic Acid Increases Interleukin-10 Levels of Peripheral Blood Monocytes in Obese Patients With Dyslipidemia

    Article • Diabetes Care, August 2012, American Diabetes Association

    Dr Tomohide Takaya

  34. Roles of MicroRNAs and Myocardial Cell Differentiation

    Article • January 2012, Elsevier

    Dr Tomohide Takaya

  35. Distinct Characteristics of Circulating Vascular Endothelial Growth Factor-A and C Levels in Human Subjects

    Article • PLOS One, December 2011, PLOS

    Dr Tomohide Takaya

  36. The Discovery of LOX-1, its Ligands and Clinical Significance

    Article • Cardiovascular Drugs and Therapy, August 2011, Springer Science + Business Media

    Dr Tomohide Takaya

  37. A Natural p300-Specific Histone Acetyltransferase Inhibitor, Curcumin, in Addition to Angiotensin-Converting Enzyme Inhibitor, Exerts Beneficial Effects on Left Ventricular Systolic Function After Myocardial Infarction in Rats

    Article • Circulation Journal, January 2011, Japanese Circulation Society

    Dr Tomohide Takaya

  38. MicroRNA-27a Regulates Beta Cardiac Myosin Heavy Chain Gene Expression by Targeting Thyroid Hormone Receptor  1 in Neonatal Rat Ventricular Myocytes

    Article • Molecular and Cellular Biology, December 2010, ASM Journals

    Dr Tomohide Takaya

  39. Cyclin-dependent kinase 9 forms a complex with GATA4 and is involved in the differentiation of mouse ES cells into cardiomyocytes

    Article • Journal of Cellular Physiology, July 2010, Wiley

    Dr Tomohide Takaya

  40. Lectin-like oxidized low-density lipoprotein receptor-1 is required for the adipose tissue expression of proinflammatory cytokines in high-fat diet-induced obese mice

    Article • Biochemical and Biophysical Research Communications, July 2010, Elsevier

    Dr Tomohide Takaya

  41. Cell line-dependent differentiation of induced pluripotent stem cells into cardiomyocytes in mice

    Article • Cardiovascular Research, June 2010, European Society of Cardiology

    Dr Tomohide Takaya

  42. Cyclin-dependent Kinase-9 Is a Component of the p300/GATA4 Complex Required for Phenylephrine-induced Hypertrophy in Cardiomyocytes

    Article • Journal of Biological Chemistry, January 2010, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Tomohide Takaya

  43. Aldosterone Signaling Associates With p300/GATA4 Transcriptional Pathway During the Hypertrophic Response of Cardiomyocytes

    Article • Circulation Journal, January 2010, Japanese Circulation Society

    Dr Tomohide Takaya

  44. Left Ventricular Expression of Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 in Failing Rat Hearts

    Article • Circulation Journal, January 2010, Japanese Circulation Society

    Dr Tomohide Takaya

  45. MicroRNA-1 and MicroRNA-133 in Spontaneous Myocardial Differentiation of Mouse Embryonic Stem Cells

    Article • Circulation Journal, January 2009, Japanese Circulation Society

    Dr Tomohide Takaya

  46. Up-regulated expression of microRNA-143 in association with obesity in adipose tissue of mice fed high-fat diet

    Article • Biochemical and Biophysical Research Communications, November 2008, Elsevier

    Dr Tomohide Takaya

  47. Statins activate GATA-6 and induce differentiated vascular smooth muscle cells

    Article • Biochemical and Biophysical Research Communications, October 2008, Elsevier

    Dr Tomohide Takaya

  48. Identification of p300-targeted Acetylated Residues in GATA4 during Hypertrophic Responses in Cardiac Myocytes

    Article • Journal of Biological Chemistry, February 2008, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Tomohide Takaya

  49. The dietary compound curcumin inhibits p300 histone acetyltransferase activity and prevents heart failure in rats

    Article • Journal of Clinical Investigation, February 2008, American Society for Clinical Investigation

    Dr Tomohide Takaya

  50. Myocardial Regulation of p300 and p53 by Doxorubicin Involves Ubiquitin Pathways

    Article • Circulation Journal, January 2008, Japanese Circulation Society

    Dr Tomohide Takaya

  51. Spaceflight results in increase of thick filament but not thin filament proteins in the paramyosin mutant of Caenorhabditis elegans

    Article • Advances in Space Research, January 2008, Elsevier

    Dr Tomohide Takaya

  52. Trichostatin A induces myocardial differentiation of monkey ES cells

    Article • Biochemical and Biophysical Research Communications, May 2007, Elsevier

    Dr Tomohide Takaya

  53. Tissue expression of four troponin I genes and their molecular interactions with two troponin C isoforms inCaenorhabditis elegans

    Article • Genes to Cells, March 2005, Wiley

    Dr Tomohide Takaya

  54. C. Elegans Model for Studying Tropomyosin and Troponin Regulations of Muscle Contraction and Animal Behavior

    Article • Springer Science + Business Media

    Dr Tomohide Takaya