All Stories

  1. Authentic Patient-Derived Hepatitis C Virus Infects and Productively Replicates in Primary CD4 + and CD8 + T Lymphocytes In Vitro

    Article • Journal of Virology, November 2017, ASM Journals

    Tomasz Michalak

  2. Primary Seronegative but Molecularly Evident Hepadnaviral Infection Engages Liver and Induces Hepatocarcinoma in the Woodchuck Model of Hepatitis B

    Article • PLoS Pathogens, August 2014, PLOS

    Tomasz Michalak

  3. P171 PRIMARY SERONEGATIVE HEPADNAVIRAL INFECTION ENGAGES LIVER OVER TIME AND INDUCES HEPATOCELLULAR CARCINOMA IN WOODCHUCK HEPATITIS B MODEL

    Article • Journal of Hepatology, April 2014, Elsevier

    Tomasz Michalak

  4. Repeated Exposure to Trace Amounts of Woodchuck Hepadnavirus Induces Molecularly Evident Infection and Virus-Specific T Cell Response in the Absence of Serological Infection Markers and Hepatitis

    Article • Journal of Virology, November 2012, ASM Journals

    Tomasz Michalak

  5. HCV Infection of Hematopoietic and Immune Cell Subsets

    Article • October 2011, Springer Science + Business Media

    Tomasz Michalak

  6. Hepatocyte cytotoxicity is facilitated by asialoglycoprotein receptor

    Article • Hepatology, July 2011, Wiley

    Tomasz Michalak

  7. Pre-acute hepadnaviral infection is associated with activation-induced apoptotic death of lymphocytes in the woodchuck (Marmota monax) model of hepatitis B

    Article • Developmental & Comparative Immunology, September 2010, Elsevier

    Tomasz Michalak

  8. Occult hepatitis C virus infection: what does it mean?

    Article • Liver International, April 2010, Wiley

    Tomasz Michalak

  9. Hepadnaviral infection augments hepatocyte cytotoxicity mediated by both CD95 ligand and perforin pathways

    Article • Liver International, March 2010, Wiley

    Tomasz Michalak

  10. Profound Antiviral Effect of Oral Administration of MIV-210 on Chronic Hepadnaviral Infection in a Woodchuck Model of Hepatitis B

    Article • Antimicrobial Agents and Chemotherapy, June 2009, ASM Journals

    Tomasz Michalak

  11. Hepatocytes as Cytotoxic Effector Cells

    Article • Current Immunology Reviews, November 2008, Bentham Science Publishers

    Tomasz Michalak

  12. Intrahepatic Expression of Genes Affiliated with Innate and Adaptive Immune Responses Immediately after Invasion and during Acute Infection with Woodchuck Hepadnavirus

    Article • Journal of Virology, July 2008, ASM Journals

    Tomasz Michalak

  13. Repeated Passage of Wild-Type Woodchuck Hepatitis Virus in Lymphoid Cells Does Not Generate Cell Type-Specific Variants or Alter Virus Infectivity

    Article • Journal of Virology, May 2008, ASM Journals

    Tomasz Michalak

  14. Aberrant Lymphocyte Activation Precedes Delayed Virus-Specific T-Cell Response after both Primary Infection and Secondary Exposure to Hepadnavirus in the Woodchuck Model of Hepatitis B Virus Infection

    Article • Journal of Virology, May 2008, ASM Journals

    Tomasz Michalak

  15. Bicistronic Woodchuck Hepatitis Virus Core and Gamma Interferon DNA Vaccine Can Protect from Hepatitis but Does Not Elicit Sterilizing Antiviral Immunity

    Article • Journal of Virology, November 2006, ASM Journals

    Tomasz Michalak

  16. Inhibition by Woodchuck Hepatitis Virus of Class I Major Histocompatibility Complex Presentation on Hepatocytes Is Mediated by Virus Envelope Pre-S2 Protein and Can Be Reversed by Treatment with Gamma Interferon

    Article • Journal of Virology, September 2006, ASM Journals

    Tomasz Michalak

  17. Characterization of bioactive recombinant woodchuck interleukin-2 amplified by RLM-RACE and produced in eukaryotic expression system

    Article • Veterinary Immunology and Immunopathology, August 2006, Elsevier

    Tomasz Michalak

  18. Hepatocytes as cytotoxic effector cells can induce cell death by CD95 ligand-mediated pathway

    Article • Hepatology, January 2006, Wiley

    Tomasz Michalak

  19. Flow Cytometric Quantification of T Cell Proliferation and Division Kinetics in Woodchuck Model of Hepatitis B

    Article • Immunological Investigations, May 2005, Taylor & Francis

    Tomasz Michalak

  20. Flow Cytometric Quantification of T Cell Proliferation and Division Kinetics in Woodchuck Model of Hepatitis B

    Article • Immunological Investigations, January 2005, Taylor & Francis

    Tomasz Michalak

  21. Persistence of isolated antibodies to woodchuck hepatitis virus core antigen is indicative of occult infection

    Article • Hepatology, October 2004, Wiley

    Tomasz Michalak

  22. Immunology of hepatitis B virus

    Article • January 2004, Springer Science + Business Media

    Tomasz Michalak

  23. Autoantibodies to asialoglycoprotein receptor and their relevance to liver function and injury in the woodchuck model of hepatitis B

    Article • Journal of Hepatology, April 2001, Elsevier

    Tomasz Michalak

  24. Autoantibodies to asialoglycoprotein receptor and their relevance to liver function and injury in the woodchuck model of hepatitis B

    Article • Journal of Hepatology, April 2001, Elsevier

    Tomasz Michalak

  25. In Vitro and In Vivo Infectivity and Pathogenicity of the Lymphoid Cell-Derived Woodchuck Hepatitis Virus

    Article • Journal of Virology, February 2001, ASM Journals

    Tomasz Michalak

  26. Posttranscriptional Inhibition of Class I Major Histocompatibility Complex Presentation on Hepatocytes and Lymphoid Cells in Chronic Woodchuck Hepatitis Virus Infection

    Article • Journal of Virology, May 2000, ASM Journals

    Tomasz Michalak

  27. Occult persistence and lymphotropism of hepadnaviral infection: insights from the woodchuck viral hepatitis model

    Article • Immunological Reviews, April 2000, Wiley

    Tomasz Michalak

  28. Perforin and Fas/Fas ligand-mediated cytotoxicity in acute and chronic woodchuck viral hepatitis

    Article • Clinical & Experimental Immunology, October 1999, Wiley

    Tomasz Michalak

  29. Persistence of infectious hepadnavirus in the offspring of woodchuck mothers recovered from viral hepatitis

    Article • Journal of Clinical Investigation, July 1999, American Society for Clinical Investigation

    Tomasz Michalak

  30. Complement-mediated cytotoxicity and inhibition of ligand binding to hepatocytes by woodchuck hepatitis virus-induced autoantibodies to asialoglycoprotein receptor

    Article • Hepatology, June 1998, Wiley

    Tomasz Michalak

  31. Protease-activated lymphoid cell and hepatocyte recognition site in the preS1 domain of the large woodchuck hepatitis virus envelope protein

    Article • Journal of General Virology, August 1996, Society for General Microbiology

    Tomasz Michalak

  32. Composition, Antigenic Properties and Hepatocyte Surface Expression of the Woodchuck Asialoglycoprotein Receptor

    Article • Journal of Receptors and Signal Transduction, January 1996, Taylor & Francis

    Tomasz Michalak

  33. Identification of woodchuck class I MHC antigens using monoclonal antibodies

    Article • Tissue Antigens, May 1995, Wiley

    Tomasz Michalak

  34. Detection of hepatitis B and woodchuck hepatitis viral DNA in plasma and mononuclear cells from heparinized blood by the polymerase chain reaction

    Article • Journal of Virological Methods, February 1995, Elsevier

    Tomasz Michalak

  35. Characterization of the incorporation of woodchuck hepatitis virus surface antigen into hepatocyte plasma membrane in woodchuck hepatitis and in the virus-induced hepatocellular carcinoma

    Article • Hepatology, July 1989, Wiley

    Tomasz Michalak

  36. Characterization of the binding sites for glutaraldehyde-polymerized albumin on purified woodchuck hepatocyte plasma membranes

    Article • Gastroenterology, January 1989, Elsevier

    Tomasz Michalak

  37. Crystalline Aggregates of Hepatitis B Core Particles in Cytoplasm of Hepatocytes

    Article • Intervirology, January 1982, Karger Publishers

    Tomasz Michalak

  38. Woodchuck Hepatitis Virus Hepatocyte Culture Models

    Article • Springer Science + Business Media

    Tomasz Michalak