All Stories

  1. A Bridge too Far? Comparison of Transition Metal Complexes of Dibenzyltetraazamacrocycles with and without Ethylene Cross-Bridges: X-ray Crystal Structures, Kinetic Stability, and Electronic Properties

    Article • Molecules, January 2023, MDPI AG

    Professor Timothy J Hubin

  2. An ethylene cross-bridged pentaazamacrocycle and its Cu2+ complex: constrained ligand topology and excellent kinetic stability

    Article • Chemical Communications, January 2020, Royal Society of Chemistry

    Professor Timothy J Hubin

  3. 64Cu PET Imaging of the CXCR4 Chemokine Receptor Using a Cross-Bridged Cyclam Bis-Tetraazamacrocyclic Antagonist

    Article • Journal of Nuclear Medicine, June 2019, Society of Nuclear Medicine

    Professor Timothy J Hubin

  4. Tetraazamacrocyclic derivatives and their metal complexes as antileishmanial leads

    Article • Polyhedron, May 2019, Elsevier

    Professor Timothy J Hubin

  5. Acetate as a model for aspartate-based CXCR4 chemokine receptor binding of cobalt and nickel complexes of cross-bridged tetraazamacrocycles

    Article • Dalton Transactions, January 2019, Royal Society of Chemistry

    Professor Timothy J Hubin

  6. Increase of Direct C–C Coupling Reaction Yield by Identifying Structural and Electronic Properties of High-Spin Iron Tetra-azamacrocyclic Complexes

    Article • Inorganic Chemistry, July 2018, American Chemical Society (ACS)

    Professor Timothy J Hubin

  7. Isosteric and Spatial Considerations of Drugs

    Article • June 2018, Bentham Science Publishers

    Professor Timothy J Hubin

  8. Synthesis and structural studies of two pyridine-armed reinforced cyclen chelators and their transition metal complexes

    Article • Polyhedron, August 2016, Elsevier

    Professor Timothy J Hubin

  9. Aspartate-Based CXCR4 Chemokine Receptor Binding of Cross-Bridged Tetraazamacrocyclic Copper(II) and Zinc(II) Complexes

    Article • Chemistry - A European Journal, July 2016, Wiley

    Professor Timothy J Hubin

  10. Discovery of Antischistosomal Drug Leads Based on Tetraazamacrocyclic Derivatives and Their Metal Complexes

    Article • Antimicrobial Agents and Chemotherapy, June 2016, ASM Journals

    Professor Timothy J Hubin

  11. Probing the Limits of Tetraazamacrocycle-Glyoxal Condensates as Bidentate Ligands for Cu2+

    Article • European Journal of Inorganic Chemistry, September 2015, Wiley

    Professor Timothy J Hubin

  12. Synthesis, structural studies, and oxidation catalysis of the manganese(II), iron(II), and copper(II) complexes of a 2-pyridylmethyl pendant armed side-bridged cyclam

    Article • Inorganic Chemistry Communications, September 2015, Elsevier

    Professor Timothy J Hubin

  13. Crystal structure of dichlorido(4,11-dimethyl-1,4,8,11-tetraazabicyclo[6.6.2]hexadecane)iron(III) hexafluoridophosphate

    Article • Acta Crystallographica Section E Crystallographic Communications, August 2015, International Union of Crystallography

    Dr Timothy J Prior, Professor Timothy J Hubin

  14. IL-24 Inhibits Lung Cancer Cell Migration and Invasion by Disrupting The SDF-1/CXCR4 Signaling Axis

    Article • PLoS ONE, March 2015, PLOS

    Professor Timothy J Hubin

  15. Synthesis, Structural Studies, and Oxidation Catalysis of the Late-First-Row-Transition-Metal Complexes of a 2-Pyridylmethyl Pendant-Armed Ethylene Cross-Bridged Cyclam

    Article • Inorganic Chemistry, March 2015, American Chemical Society (ACS)

    Professor Timothy J Hubin

  16. Synthesis, structural studies, kinetic stability, and oxidation catalysis of the late first row transition metal complexes of 4,10-dimethyl-1,4,7,10-tetraazabicyclo[6.5.2]pentadecane

    Article • Dalton Transactions, January 2015, Royal Society of Chemistry

    Professor Timothy J Hubin

  17. Influence of Calcium(II) and Chloride on the Oxidative Reactivity of a Manganese(II) Complex of a Cross-Bridged Cyclen Ligand

    Article • Inorganic Chemistry, November 2014, American Chemical Society (ACS)

    Professor Timothy J Hubin

  18. Synthesis of Novel Tetraazamacrocyclic Bisquinoline Derivatives as Potential Antimalarial Agents

    Article • Current Organic Synthesis, October 2014, Bentham Science Publishers

    Professor Timothy J Hubin

  19. Crystal structures of two cross-bridged chromium(III) tetraazamacrocycles

    Article • Acta Crystallographica Section E Structure Reports Online, August 2014, International Union of Crystallography

    Dr Timothy J Prior, Professor Timothy J Hubin

  20. Synthesis and antimalarial activity of metal complexes of cross-bridged tetraazamacrocyclic ligands

    Article • Bioorganic & Medicinal Chemistry, July 2014, Elsevier

    Professor Timothy J Hubin

  21. Copper(I) and copper(II) complexes with pyrazine-containing pyridylalkylamide ligands N-(pyridin-2-ylmethyl)pyrazine-2-carboxamide and N-(2-(pyridin-2-yl)ethyl)pyrazine-2-carboxamide

    Article • Journal of Coordination Chemistry, December 2013, Taylor & Francis

    Professor Timothy J Hubin

  22. CXCR4 chemokine receptor antagonists: nickel(ii) complexes of configurationally restricted macrocycles

    Article • Dalton Transactions, January 2012, Royal Society of Chemistry

    Steve Archibald, Professor Timothy J Hubin

  23. Preparations and applications of synthetic linked azamacrocycle ligands and complexes

    Article • Coordination Chemistry Reviews, August 2010, Elsevier

    Professor Timothy J Hubin

  24. ChemInform Abstract: Template Control of Supramolecular Architecture

    Article • ChemInform, June 2010, Wiley

    Professor Timothy J Hubin

  25. ChemInform Abstract: An o-Xylyl Cross-Bridged 5,12-Dioxocyclam.

    Article • ChemInform, June 2010, Wiley

    Professor Timothy J Hubin

  26. CXCR4 Chemokine Receptor Antagonists from Ultra-rigid Metal Complexes Profoundly Inhibit HIV-1 Replication, and also AMD3100-resistant Strains

    Article • Antiviral Research, May 2009, Elsevier

    Steve Archibald, Professor Timothy J Hubin

  27. CXCR4 Antagonists: A New Generation of Configurationally Restricted Bis-azamacrocyclic Compounds

    Article • Antiviral Research, May 2009, Elsevier

    Steve Archibald, Professor Timothy J Hubin

  28. Synthesis and characterization of the chromium(III) complexes of ethylene cross-bridged cyclam and cyclen ligands

    Article • Inorganica Chimica Acta, April 2009, Elsevier

    Steve Archibald, Professor Timothy J Hubin

  29. Binding Optimization through Coordination Chemistry: CXCR4 Chemokine Receptor Antagonists from Ultrarigid Metal Complexes

    Article • Journal of the American Chemical Society, February 2009, American Chemical Society (ACS)

    Steve Archibald, Professor Timothy J Hubin

  30. The design and synthesis of pyrazine amide ligands suitable for the “tiles” approach to molecular weaving with octahedral metal ions

    Article • Inorganic Chemistry Communications, January 2008, Elsevier

    Steve Archibald, Professor Timothy J Hubin

  31. Dichloro(4,10-dimethyl-1,4,7,10-tetraazabicyclo[5.5.2]tetradecane)iron(III) hexafluorophosphate

    Article • Acta Crystallographica Section C Crystal Structure Communications, October 2006, International Union of Crystallography

    Professor Timothy J Hubin

  32. Configurationally Restricted Bismacrocyclic CXCR4 Receptor Antagonists

    Article • Journal of Medicinal Chemistry, September 2006, American Chemical Society (ACS)

    Steve Archibald, Professor Timothy J Hubin

  33. Synthesis and characterization of the cobalt(III) complexes of two pendant-arm cross-bridged cyclams

    Article • Inorganica Chimica Acta, January 2004, Elsevier

    Steve Archibald, Professor Timothy J Hubin

  34. Rigidity extremes in coordination chemistry: a fine energetic balance in the isolation of a trapped ligand inversion intermediateElectronic supplementary information (ESI) available: Experimental, crystallographic and computational details. See http://...

    Article • Chemical Communications, January 2004, Royal Society of Chemistry

    Steve Archibald, Professor Timothy J Hubin

  35. Synthesis and coordination chemistry of topologically constrained azamacrocycles

    Article • Coordination Chemistry Reviews, June 2003, Elsevier

    Professor Timothy J Hubin

  36. Synthesis, structure, and stability in acid of copper(II) and zinc(II) complexes of cross-bridged tetraazamacrocycles

    Article • Inorganica Chimica Acta, May 2003, Elsevier

    Professor Timothy J Hubin

  37. Synthesis and X-ray crystal structures of iron(II) and manganese(II) complexes of unsubstituted and benzyl substituted cross-bridged tetraazamacrocycles

    Article • Inorganica Chimica Acta, March 2003, Elsevier

    Professor Timothy J Hubin

  38. Synthesis and X-ray Crystal Structure Determination of the First Copper(II) Complexes of Tetraazamacrocycle−Glyoxal Condensates

    Article • Inorganic Chemistry, December 2002, American Chemical Society (ACS)

    Professor Timothy J Hubin

  39. Synthesis, characterization, and X-ray crystal structures of cobalt(II) and cobalt(III) complexes of four topologically constrained tetraazamacrocycles

    Article • Inorganica Chimica Acta, September 2002, Elsevier

    Professor Timothy J Hubin

  40. trans-Dioxocyclam (1,4,8,11-tetraazacyclotetradecane-2,9-dione) dihydrate and its NiIIcomplex

    Article • Acta Crystallographica Section C Crystal Structure Communications, April 2001, International Union of Crystallography

    Professor Timothy J Hubin

  41. Potentiometric Titrations and Nickel(II) Complexes of Four Topologically Constrained Tetraazamacrocycles

    Article • Supramolecular Chemistry, March 2001, Taylor & Francis

    Professor Timothy J Hubin

  42. SYNTHESIS AND CHARACTERIZATION OF THE NOVEL BRIDGED LIGAND 5,8-DIMETHYL-1,5,8,12-TETRAAZABICYCLO[10.3.2]HEPTADECANE AND ITS COMPLEXES WITH IRON(II) AND MANAGANESE(II) IONS

    Article • Journal of Coordination Chemistry, February 2001, Taylor & Francis

    Professor Timothy J Hubin

  43. Topologically Constrained Manganese(III) and Iron(III) Complexes of Two Cross-Bridged Tetraazamacrocycles

    Article • Inorganic Chemistry, January 2001, American Chemical Society (ACS)

    Professor Timothy J Hubin

  44. Template routes to interlocked molecular structures and orderly molecular entanglements

    Article • Coordination Chemistry Reviews, May 2000, Elsevier

    Professor Timothy J Hubin

  45. New Iron(II) and Manganese(II) Complexes of Two Ultra-Rigid, Cross-Bridged Tetraazamacrocycles for Catalysis and Biomimicry

    Article • Journal of the American Chemical Society, March 2000, American Chemical Society (ACS)

    Professor Timothy J Hubin

  46. Copper(I) and copper(II) complexes of an ethylene cross-bridged cyclam

    Article • Acta Crystallographica Section C Crystal Structure Communications, January 2000, International Union of Crystallography

    Professor Timothy J Hubin

  47. A cyclam-like macrocycle side-bridged by a propyl chain

    Article • Acta Crystallographica Section C Crystal Structure Communications, December 1999, International Union of Crystallography

    Professor Timothy J Hubin

  48. Ano-xylyl cross-bridged 5,12-dioxocyclam

    Article • Acta Crystallographica Section C Crystal Structure Communications, November 1999, International Union of Crystallography

    Professor Timothy J Hubin

  49. Crystallographic Characterization of Stepwise Changes in Ligand Conformations as Their Internal Topology Changes and Two Novel Cross-Bridged Tetraazamacrocyclic Copper(II) Complexes

    Article • Inorganic Chemistry, October 1999, American Chemical Society (ACS)

    Professor Timothy J Hubin

  50. The square-pyramidal PdIIcomplex of a cross-bridged tetraazamacrocycle

    Article • Acta Crystallographica Section C Crystal Structure Communications, September 1999, International Union of Crystallography

    Professor Timothy J Hubin

  51. Template control of supramolecular architecture

    Article • January 1999, Elsevier

    Professor Timothy J Hubin

  52. Synthesis and X-ray Crystal Structure Determination of the First Transition Metal Complexes of the Tetracycles Formed by Tetraazamacrocycle−Glyoxal Condensation:  PdL*Cl 2 (L = Cyclam−Glyoxal Condensate ( 1 ), Cyclen−Glyoxal Condensate ( 2 ))

    Article • Inorganic Chemistry, December 1998, American Chemical Society (ACS)

    Professor Timothy J Hubin

  53. Ultra rigid cross-bridged tetraazamacrocycles as ligands—the challenge and the solution

    Article • Chemical Communications, January 1998, Royal Society of Chemistry

    Professor Timothy J Hubin