All Stories

  1. Development and characterization of a topical ferrochelatase inhibitor nanoemulsion for choroidal neovascularization therapy

    Article • International Journal of Pharmaceutics X, December 2026, Elsevier

    Tim Corson, Seung-Yong Seo

  2. Diagnostic and therapeutic potential of carbon nanodots for ocular disease

    Article • Nanomedicine, August 2026, Taylor & Francis

    Tim Corson

  3. Assessment of anti-VEGF intravitreal injection effects on murine neonatal Schlemm’s canal morphology

    Article • Scientific Reports, July 2026, Springer Science + Business Media

    Tim Corson

  4. High-fat Western diet induces retinal and metabolic alterations in APOE3 and APOE4 knock-in mice

    Article • Scientific Reports, January 2026, Springer Science + Business Media

    Tim Corson

  5. Müller Glial Kir4.1 Channel Dysfunction in APOE4 ‐ KI Model of Alzheimer's Disease

    Article • Glia, January 2026, Wiley

    Tim Corson

  6. Sulphur Analogues of Homoisoflavonoids as Potential Treatments for Neovascular Eye Diseases

    Article • ChemMedChem, January 2026, Wiley

    Tim Corson

  7. Emulsion and Emulgel-Based Ophthalmic Drug Delivery Systems

    Article • Pharmaceutics, November 2025, MDPI AG

    Tim Corson

  8. Angiogenesis Signaling in Retinoblastoma: Prognostic and Therapeutic Applications

    Article • International Ophthalmology Clinics, September 2025, Wolters Kluwer Health

    Tim Corson

  9. Long-term Dietary Fat Intervention Affects Retinal Health in APOE Mice

    Article • August 2025, Cold Spring Harbor Laboratory Press

    Tim Corson

  10. Ref-1 redox activity modulates canonical Wnt signaling in endothelial cells

    Article • Redox Biology, June 2025, Elsevier

    Tim Corson

  11. Nanovesicular ultra-deformable transferosomes and transgelosomes for ocular drug delivery

    Article • Nanomedicine, May 2025, Taylor & Francis

    Tim Corson

  12. Retinoma: An overview

    Article • Pediatric Investigation, March 2025, Wiley

    Tim Corson

  13. Heme promotes venetoclax resistance in multiple myeloma through MEK-ERK signaling and purine biosynthesis

    Article • Blood, February 2025, American Society of Hematology

    Tim Corson

  14. Ref‐1 redox activity regulates retinal neovascularization by modulating transcriptional activation of HIF ‐1α

    Article • The FASEB Journal, February 2025, Wiley

    Tim Corson

  15. Ref-1 is overexpressed in neovascular eye disease and targetable with a novel inhibitor

    Article • Angiogenesis, January 2025, Springer Science + Business Media

    Tim Corson

  16. Retinal dysfunction in APOE4 knock‐in mouse model of Alzheimer's disease

    Article • Alzheimer s & Dementia, January 2025, Wiley

    Tim Corson

  17. Ref-1 redox activity modulates canonical Wnt signaling in endothelial cells

    Article • Free Radical Biology and Medicine, November 2024, Elsevier

    Tim Corson

  18. Exploring the Antiangiogenic and Anti-Inflammatory Potential of Homoisoflavonoids: Target Identification Using Biotin Probes

    Article • Biomolecules, June 2024, MDPI AG

    Tim Corson, Seung-Yong Seo

  19. Challenges and opportunities of developing small-molecule therapies for age-related macular degeneration

    Article • Archives of Pharmacal Research, June 2024, Springer Science + Business Media

    Seung-Yong Seo, Tim Corson

  20. AI is a viable alternative to high throughput screening: a 318-target study

    Article • Scientific Reports, April 2024, Springer Science + Business Media

    Davide M Ferraris, Jose A. Costoya, Dr Kiterie ME Faller, Dr Graeme L Conn, Tim Corson

  21. The Potential of Aqueous Humor Sampling in Diagnosis, Prognosis, and Treatment of Retinoblastoma

    Article • Investigative Ophthalmology & Visual Science, January 2024, Association for Research in Vision and Ophthalmology (ARVO)

    Tim Corson

  22. Long‐Acting Microparticle Formulation of Griseofulvin for Ocular Neovascularization Therapy

    Article • Small, November 2023, Wiley

    Tim Corson

  23. Homoisoflavonoids from the Asparagaceae family for use against ocular angiogenesis

    Article • Planta Medica, November 2023, Thieme Publishing Group

    Tim Corson

  24. Beyond VEGF: Targeting Inflammation and Other Pathways for Treatment of Retinal Disease

    Article • Journal of Pharmacology and Experimental Therapeutics, July 2023, Elsevier

    Tim Corson

  25. Antiangiogenic Pterocarpan and Flavonoid Constituents of Erythrina lysistemon

    Article • Journal of Natural Products, March 2023, American Chemical Society (ACS)

    Tim Corson

  26. PRMT5 is a therapeutic target in choroidal neovascularization

    Article • Scientific Reports, January 2023, Springer Science + Business Media

    Tim Corson

  27. Identification of Novel Pathways Regulated by APE1/Ref-1 in Human Retinal Endothelial Cells

    Article • International Journal of Molecular Sciences, January 2023, MDPI AG

    Tim Corson

  28. Synthesis and Structure Revision of Naturally Occurring Homoisoflavane (+)-Dracaeconolide B

    Article • Journal of Natural Products, December 2022, American Chemical Society (ACS)

    Tim Corson

  29. Decreased Expression of Soluble Epoxide Hydrolase Suppresses Murine Choroidal Neovascularization

    Article • International Journal of Molecular Sciences, December 2022, MDPI AG

    Tim Corson

  30. Homoisoflavonoids from Eucomis bicolour, Eucomis autumnalis and Scilla peruviana (Asparagaceae)

    Article • Planta Medica, December 2022, Thieme Publishing Group

    Tim Corson

  31. Synthesis of Derivatised Homoisoflavonoids to Target Ocular Angiogenesis

    Article • Planta Medica, December 2022, Thieme Publishing Group

    Tim Corson

  32. Mouse Pharmacokinetics and In Vitro Metabolism of SH-11037 and SH-11008, Synthetic Homoisoflavonoids for Retinal Neovascularization

    Article • Pharmaceutics, October 2022, MDPI AG

    Tim Corson, Seung-Yong Seo

  33. The Global Retinoblastoma Outcome Study: a prospective, cluster-based analysis of 4064 patients from 149 countries

    Article • The Lancet Global Health, August 2022, Elsevier

    Tim Corson

  34. Small-molecule inhibitors of ferrochelatase are antiangiogenic agents

    Article • Cell Chemical Biology, June 2022, Elsevier

    Tim Corson

  35. PRMT5 is a therapeutic target in choroidal neovascularization

    Article • March 2022, openRxiv

    Tim Corson

  36. An improved method for murine laser-induced choroidal neovascularization lesion quantification from optical coherence tomography images

    Article • MethodsX, January 2022, Elsevier

    Tim Corson

  37. Inhibition of APE1/Ref-1 for Neovascular Eye Diseases: From Biology to Therapy

    Article • International Journal of Molecular Sciences, September 2021, MDPI AG

    Tim Corson

  38. Patient preferences in retinal drug delivery

    Article • Scientific Reports, September 2021, Springer Science + Business Media

    Tim Corson

  39. Building a virtual summer research experience in cancer for high school and early undergraduate students: lessons from the COVID-19 pandemic

    Article • BMC Medical Education, August 2021, Springer Science + Business Media

    Tim Corson

  40. Measurement of mitochondrial respiration in the murine retina using a Seahorse extracellular flux analyzer

    Article • STAR Protocols, June 2021, Elsevier

    Tim Corson

  41. A smartphone based method for mouse fundus imaging

    Article • Experimental Eye Research, May 2021, Elsevier

    Tim Corson

  42. Retinal Phenotyping of Ferrochelatase Mutant Mice Reveals Protoporphyrin Accumulation and Reduced Neovascular Response

    Article • Investigative Ophthalmology & Visual Science, February 2021, Association for Research in Vision and Ophthalmology (ARVO)

    Tim Corson

  43. NF-κB Signaling Is Regulated by Fucosylation in Metastatic Breast Cancer Cells

    Article • Biomedicines, December 2020, MDPI AG

    Tim Corson

  44. Building a virtual summer research experience in cancer for high school and early undergraduate students: lessons from the COVID-19 pandemic

    Article • November 2020, Cold Spring Harbor Laboratory Press

    Tim Corson

  45. Cancer Research in the “Chemical Biology” Section of the Journal Molecules

    Article • Molecules, November 2020, MDPI AG

    Tim Corson

  46. Heme Synthesis Inhibition Blocks Angiogenesis via Mitochondrial Dysfunction

    Article • iScience, August 2020, Elsevier

    Tim Corson

  47. Pharmacological Potential of Small Molecules for Treating Corneal Neovascularization

    Article • Molecules, July 2020, MDPI AG

    Tim Corson

  48. Ferrochelatase regulates retinal neovascularization

    Article • The FASEB Journal, July 2020, Wiley

    Tim Corson

  49. Mitochondrial Heme Synthesis Enzymes as Therapeutic Targets in Vascular Diseases

    Article • Frontiers in Pharmacology, July 2020, Frontiers

    Tim Corson

  50. Ferrochelatase regulates retinal neovascularization

    Article • June 2020, Cold Spring Harbor Laboratory Press

    Tim Corson

  51. Total Synthesis of Naturally Occurring 5,7,8-Trioxygenated Homoisoflavonoids

    Article • ACS Omega, May 2020, American Chemical Society (ACS)

    Tim Corson, Seung-Yong Seo

  52. Phenotypic Screening of Chemical Libraries Enriched by Molecular Docking to Multiple Targets Selected from Glioblastoma Genomic Data

    Article • ACS Chemical Biology, April 2020, American Chemical Society (ACS)

    Tim Corson

  53. Bufadienolides and anti-angiogenic homoisoflavonoids from Rhodocodon cryptopodus, Rhodocodon rotundus and Rhodocodon cyathiformis

    Article • Fitoterapia, March 2020, Elsevier

    Tim Corson

  54. Global Retinoblastoma Presentation and Analysis by National Income Level

    Article • JAMA Oncology, February 2020, American Medical Association (AMA)

    Prof. Hind M Alkatan, Erika Maka, Tim Corson

  55. Bufadienolides and anti-angiogenic homoisoflavonoids from Rhodocodon cryptopodus,Rhodocodon rotundus and Rhodocodon cyathiformis

    Article • Planta Medica, December 2019, Thieme Publishing Group

    Tim Corson

  56. Heme synthesis inhibition blocks angiogenesis via mitochondrial dysfunction

    Article • November 2019, Cold Spring Harbor Laboratory Press

    Tim Corson

  57. Enantioselective Synthesis of Homoisoflavanones by Asymmetric Transfer Hydrogenation and Their Biological Evaluation for Antiangiogenic Activity

    Article • The Journal of Organic Chemistry, August 2019, American Chemical Society (ACS)

    Tim Corson

  58. The Antiangiogenic Activity of Naturally Occurring and Synthetic Homoisoflavonoids from the Hyacinthaceae (sensu APGII)

    Article • Journal of Natural Products, April 2019, American Chemical Society (ACS)

    Tim Corson

  59. Small-Molecule Covalent Modification of Conserved Cysteine Leads to Allosteric Inhibition of the TEAD⋅Yap Protein-Protein Interaction

    Article • Cell Chemical Biology, March 2019, Elsevier

    Tim Corson

  60. Soluble Epoxide Hydrolase Inhibition for Ocular Diseases: Vision for the Future

    Article • Frontiers in Pharmacology, February 2019, Frontiers

    Tim Corson

  61. Small molecule target identification using photo-affinity chromatography

    Article • January 2019, Elsevier

    Tim Corson

  62. Observations on spontaneous tumor formation in mice overexpressing mitotic kinesin Kif14

    Article • Scientific Reports, November 2018, Springer Science + Business Media

    Tim Corson

  63. Small molecules inhibit ex vivo tumor growth in bone

    Article • Bioorganic & Medicinal Chemistry, November 2018, Elsevier

    Tim Corson

  64. Ref-1/APE1 Inhibition with Novel Small Molecules Blocks Ocular Neovascularization

    Article • Journal of Pharmacology and Experimental Therapeutics, August 2018, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Tim Corson

  65. Antiangiogenic Activity and Cytotoxicity of Triterpenoids and Homoisoflavonoids from Massonia pustulata and Massonia bifolia

    Article • Planta Medica, February 2018, Thieme Publishing Group

    Tim Corson

  66. Retinoblastoma, the visible CNS tumor: A review

    Article • Journal of Neuroscience Research, January 2018, Wiley

    Tim Corson

  67. Chemical Proteomics Reveals Soluble Epoxide Hydrolase as a Therapeutic Target for Ocular Neovascularization

    Article • ACS Chemical Biology, December 2017, American Chemical Society (ACS)

    Tim Corson

  68. Abstract 2814: Effect of kif14 overexpression on tumor formation in mice in a lifespan study

    Article • Cancer Research, July 2017, American Association for Cancer Research (AACR)

    Tim Corson

  69. Ferrochelatase is a therapeutic target for ocular neovascularization

    Article • EMBO Molecular Medicine, April 2017, EMBO

    Seung-Yong Seo, Tim Corson

  70. Novel bioactive homoisoflavonoids from Madagascan Rhodocodon species (Hyacinthaceae, sensu APG II)

    Article • Planta Medica, December 2016, Thieme Publishing Group

    Tim Corson

  71. Design, synthesis and biological evaluation of photoaffinity probes of antiangiogenic homoisoflavonoids

    Article • Bioorganic & Medicinal Chemistry Letters, September 2016, Elsevier

    Seung-Yong Seo, Tim Corson

  72. Synthesis of Natural Homoisoflavonoids Having Either 5,7-Dihydroxy-6-methoxy or 7-Hydroxy-5,6-dimethoxy Groups

    Article • Molecules, August 2016, MDPI AG

    Seung-Yong Seo, Tim Corson

  73. Molecular analysis distinguishes metastatic disease from second cancers in patients with retinoblastoma

    Article • Cancer Genetics, July 2016, Elsevier

    Tim Corson

  74. Kif14overexpression accelerates murine retinoblastoma development

    Article • International Journal of Cancer, June 2016, Wiley

    Tim Corson

  75. A novel small molecule ameliorates ocular neovascularisation and synergises with anti-VEGF therapy

    Article • Scientific Reports, May 2016, Springer Science + Business Media

    Tim Corson

  76. A Simple Optical Coherence Tomography Quantification Method for Choroidal Neovascularization

    Article • Journal of Ocular Pharmacology and Therapeutics, October 2015, Mary Ann Liebert Inc

    Tim Corson

  77. Retinoblastoma

    Article • Nature Reviews Disease Primers, August 2015, Springer Science + Business Media

    Tim Corson

  78. Synthesis and Biological Evaluation of Novel Homoisoflavonoids for Retinal Neovascularization

    Article • Journal of Medicinal Chemistry, June 2015, American Chemical Society (ACS)

    Tim Corson

  79. Cancer Genetics Education in a Low- to Middle-Income Country: Evaluation of an Interactive Workshop for Clinicians in Kenya

    Article • PLOS One, June 2015, PLOS

    Tim Corson

  80. Kif14: A Clinically Relevant Kinesin and Potential Target for Cancer Therapy

    Article • January 2015, Springer Science + Business Media

    Tim Corson

  81. Natural product inhibitors of ocular angiogenesis

    Article • Experimental Eye Research, December 2014, Elsevier

    Tim Corson

  82. Primary cilia signaling mediates intraocular pressure sensation

    Article • Proceedings of the National Academy of Sciences, August 2014, Proceedings of the National Academy of Sciences

    Tim Corson

  83. Multimodality Imaging Methods for Assessing Retinoblastoma Orthotopic Xenograft Growth and Development

    Article • PLOS One, June 2014, PLOS

    Tim Corson

  84. Synthesis and Mechanistic Studies of a Novel Homoisoflavanone Inhibitor of Endothelial Cell Growth

    Article • PLOS One, April 2014, PLOS

    Tim Corson

  85. Transcriptional and Epigenetic Regulation of KIF14 Overexpression in Ovarian Cancer

    Article • PLOS One, March 2014, PLOS

    Tim Corson

  86. KIF14 Promotes AKT Phosphorylation and Contributes to Chemoresistance in Triple-Negative Breast Cancer

    Article • Neoplasia, March 2014, Elsevier

    Tim Corson

  87. The first synthesis of the antiangiogenic homoisoflavanone, cremastranone

    Article • Organic & Biomolecular Chemistry, January 2014, Royal Society of Chemistry

    Seung-Yong Seo, Tim Corson

  88. The genomic landscape of retinoblastoma: a review

    Article • Clinical and Experimental Ophthalmology, May 2013, Wiley

    Tim Corson

  89. Posttranslational protein knockdown coupled to receptor tyrosine kinase activation with phosphoPROTACs

    Article • Proceedings of the National Academy of Sciences, May 2013, Proceedings of the National Academy of Sciences

    Tim Corson

  90. Characterisation of retinoblastomas without RB1 mutations: genomic, gene expression, and clinical studies

    Article • The Lancet Oncology, April 2013, Elsevier

    Tim Corson

  91. KIF14 as an oncogene in retinoblastoma: a target for novel therapeutics?

    Article • Future Medicinal Chemistry, November 2012, Future Science

    Tim Corson

  92. Retinoblastoma tumorigenesis: genetic and epigenetic changes walk hand in hand

    Article • Future Oncology, May 2012, Future Medicine

    Tim Corson

  93. Author Response: Does the Time of Inactivation of pRb Determine the Cell of Origin of Retinoblastoma?

    Article • Investigative Ophthalmology & Visual Science, February 2012, Association for Research in Vision and Ophthalmology (ARVO)

    Tim Corson

  94. The TAg-RB Murine Retinoblastoma Cell of Origin Has Immunohistochemical Features of Differentiated Müller Glia with Progenitor Properties

    Article • Investigative Ophthalmology & Visual Science, September 2011, Association for Research in Vision and Ophthalmology (ARVO)

    Tim Corson

  95. Small-molecule hydrophobic tagging–induced degradation of HaloTag fusion proteins

    Article • Nature Chemical Biology, July 2011, Springer Science + Business Media

    Tim Corson

  96. Triptolide Directly Inhibits dCTP Pyrophosphatase

    Article • ChemBioChem, June 2011, Wiley

    Tim Corson

  97. HIV Protease-Mediated Activation of Sterically Capped Proteasome Inhibitors and Substrates

    Article • Journal of the American Chemical Society, February 2011, American Chemical Society (ACS)

    Tim Corson

  98. Bcl-2 SNP rs956572 associates with disrupted intracellular calcium homeostasis in bipolar I disorder

    Article • Bipolar Disorders, February 2011, Wiley

    Tim Corson

  99. Design and Applications of Bifunctional Small Molecules: Why Two Heads Are Better Than One

    Article • ACS Chemical Biology, November 2008, American Chemical Society (ACS)

    Tim Corson

  100. Loss of RB1 induces non-proliferative retinoma: increasing genomic instability correlates with progression to retinoblastoma

    Article • Human Molecular Genetics, January 2008, Oxford University Press (OUP)

    Tim Corson

  101. Using expression profiling data to identify human microRNA targets

    Article • Nature Chemical Biology, November 2007, Springer Science + Business Media

    Tim Corson

  102. High Expression ofKIF14in Retinoblastoma: Association with Older Age at Diagnosis

    Article • Investigative Ophthalmology & Visual Science, November 2007, Association for Research in Vision and Ophthalmology (ARVO)

    Tim Corson

  103. Molecular Understanding and Modern Application of Traditional Medicines: Triumphs and Trials

    Article • Cell, September 2007, Elsevier

    Tim Corson

  104. KIF14 Messenger RNA Expression Is Independently Prognostic for Outcome in Lung Cancer

    Article • Clinical Cancer Research, June 2007, American Association for Cancer Research (AACR)

    Tim Corson

  105. One hit, two hits, three hits, more? Genomic changes in the development of retinoblastoma

    Article • Genes Chromosomes and Cancer, January 2007, Wiley

    Tim Corson

  106. Profiling genomic copy number changes in retinoblastoma beyond loss ofRB1

    Article • Genes Chromosomes and Cancer, January 2006, Wiley

    Tim Corson

  107. KIF14 mRNA expression is a predictor of grade and outcome in breast cancer

    Article • International Journal of Cancer, January 2006, Wiley

    Tim Corson

  108. Distinct patterns of expression of the RB gene family in mouse and human retina

    Article • Gene Expression Patterns, June 2005, Elsevier

    Tim Corson

  109. KIF14 is a candidate oncogene in the 1q minimal region of genomic gain in multiple cancers

    Article • Oncogene, May 2005, Springer Science + Business Media

    Tim Corson

  110. Cell-type specific regulation of calreticulin and Bcl-2 expression by mood stabilizer drugs

    Article • European Neuropsychopharmacology, March 2004, Elsevier

    Tim Corson

  111. Chronic Lithium Treatment Attenuates Intracellular Calcium Mobilization

    Article • Neuropsychopharmacology, February 2004, Springer Science + Business Media

    Tim Corson

  112. Association analysis of G-protein β3 subunit gene with altered Ca2+ homeostasis in bipolar disorder

    Article • Molecular Psychiatry, March 2001, Springer Science + Business Media

    Tim Corson