All Stories

  1. Heme synthesis inhibition blocks angiogenesis via mitochondrial dysfunction

    Article • November 2019, Cold Spring Harbor Laboratory Press

    Tim Corson

  2. Observations on spontaneous tumor formation in mice overexpressing mitotic kinesin Kif14

    Article • Scientific Reports, November 2018, Springer Science + Business Media

    Tim Corson

  3. Small molecules inhibit ex vivo tumor growth in bone

    Article • Bioorganic & Medicinal Chemistry, November 2018, Elsevier

    Tim Corson

  4. Ref-1/APE1 Inhibition with Novel Small Molecules Blocks Ocular Neovascularization

    Article • Journal of Pharmacology and Experimental Therapeutics, August 2018, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Tim Corson

  5. Retinoblastoma, the visible CNS tumor: A review

    Article • Journal of Neuroscience Research, January 2018, Wiley

    Tim Corson

  6. Ferrochelatase is a therapeutic target for ocular neovascularization

    Article • EMBO Molecular Medicine, April 2017, EMBO

    Seung-Yong Seo, Tim Corson

  7. Design, synthesis and biological evaluation of photoaffinity probes of antiangiogenic homoisoflavonoids

    Article • Bioorganic & Medicinal Chemistry Letters, September 2016, Elsevier

    Seung-Yong Seo, Tim Corson

  8. Synthesis of Natural Homoisoflavonoids Having Either 5,7-Dihydroxy-6-methoxy or 7-Hydroxy-5,6-dimethoxy Groups

    Article • Molecules, August 2016, MDPI AG

    Seung-Yong Seo, Tim Corson

  9. Molecular analysis distinguishes metastatic disease from second cancers in patients with retinoblastoma

    Article • Cancer Genetics, July 2016, Elsevier

    Tim Corson

  10. Kif14overexpression accelerates murine retinoblastoma development

    Article • International Journal of Cancer, June 2016, Wiley

    Tim Corson

  11. A novel small molecule ameliorates ocular neovascularisation and synergises with anti-VEGF therapy

    Article • Scientific Reports, May 2016, Springer Science + Business Media

    Tim Corson

  12. A Simple Optical Coherence Tomography Quantification Method for Choroidal Neovascularization

    Article • Journal of Ocular Pharmacology and Therapeutics, October 2015, Mary Ann Liebert Inc

    Tim Corson

  13. Retinoblastoma

    Article • Nature Reviews Disease Primers, August 2015, Springer Science + Business Media

    Tim Corson

  14. Synthesis and Biological Evaluation of Novel Homoisoflavonoids for Retinal Neovascularization

    Article • Journal of Medicinal Chemistry, June 2015, American Chemical Society (ACS)

    Tim Corson

  15. Cancer Genetics Education in a Low- to Middle-Income Country: Evaluation of an Interactive Workshop for Clinicians in Kenya

    Article • PLoS ONE, June 2015, PLOS

    Tim Corson

  16. Kif14: A Clinically Relevant Kinesin and Potential Target for Cancer Therapy

    Article • January 2015, Springer Science + Business Media

    Tim Corson

  17. Natural product inhibitors of ocular angiogenesis

    Article • Experimental Eye Research, December 2014, Elsevier

    Tim Corson

  18. Primary cilia signaling mediates intraocular pressure sensation

    Article • Proceedings of the National Academy of Sciences, August 2014, Proceedings of the National Academy of Sciences

    Tim Corson

  19. Multimodality Imaging Methods for Assessing Retinoblastoma Orthotopic Xenograft Growth and Development

    Article • PLoS ONE, June 2014, PLOS

    Tim Corson

  20. Synthesis and Mechanistic Studies of a Novel Homoisoflavanone Inhibitor of Endothelial Cell Growth

    Article • PLoS ONE, April 2014, PLOS

    Tim Corson

  21. Transcriptional and Epigenetic Regulation of KIF14 Overexpression in Ovarian Cancer

    Article • PLoS ONE, March 2014, PLOS

    Tim Corson

  22. KIF14 Promotes AKT Phosphorylation and Contributes to Chemoresistance in Triple-Negative Breast Cancer

    Article • Neoplasia, March 2014, Elsevier

    Tim Corson

  23. The first synthesis of the antiangiogenic homoisoflavanone, cremastranone

    Article • Organic & Biomolecular Chemistry, January 2014, Royal Society of Chemistry

    Seung-Yong Seo, Tim Corson

  24. The genomic landscape of retinoblastoma: a review

    Article • Clinical and Experimental Ophthalmology, May 2013, Wiley

    Tim Corson

  25. Posttranslational protein knockdown coupled to receptor tyrosine kinase activation with phosphoPROTACs

    Article • Proceedings of the National Academy of Sciences, May 2013, Proceedings of the National Academy of Sciences

    Tim Corson

  26. Characterisation of retinoblastomas without RB1 mutations: genomic, gene expression, and clinical studies

    Article • The Lancet Oncology, April 2013, Elsevier

    Tim Corson

  27. KIF14 as an oncogene in retinoblastoma: a target for novel therapeutics?

    Article • Future Medicinal Chemistry, November 2012, Future Science

    Tim Corson

  28. Retinoblastoma tumorigenesis: genetic and epigenetic changes walk hand in hand

    Article • Future Oncology, May 2012, Future Medicine

    Tim Corson

  29. Author Response: Does the Time of Inactivation of pRb Determine the Cell of Origin of Retinoblastoma?

    Article • Investigative Ophthalmology & Visual Science, February 2012, Association for Research in Vision and Ophthalmology (ARVO)

    Tim Corson

  30. The TAg-RB Murine Retinoblastoma Cell of Origin Has Immunohistochemical Features of Differentiated Müller Glia with Progenitor Properties

    Article • Investigative Ophthalmology & Visual Science, September 2011, Association for Research in Vision and Ophthalmology (ARVO)

    Tim Corson

  31. Small-molecule hydrophobic tagging–induced degradation of HaloTag fusion proteins

    Article • Nature Chemical Biology, July 2011, Springer Science + Business Media

    Tim Corson

  32. Triptolide Directly Inhibits dCTP Pyrophosphatase

    Article • ChemBioChem, June 2011, Wiley

    Tim Corson

  33. HIV Protease-Mediated Activation of Sterically Capped Proteasome Inhibitors and Substrates

    Article • Journal of the American Chemical Society, February 2011, American Chemical Society (ACS)

    Tim Corson

  34. Bcl-2 SNP rs956572 associates with disrupted intracellular calcium homeostasis in bipolar I disorder

    Article • Bipolar Disorders, February 2011, Wiley

    Tim Corson

  35. Design and Applications of Bifunctional Small Molecules: Why Two Heads Are Better Than One

    Article • ACS Chemical Biology, November 2008, American Chemical Society (ACS)

    Tim Corson

  36. Loss of RB1 induces non-proliferative retinoma: increasing genomic instability correlates with progression to retinoblastoma

    Article • Human Molecular Genetics, January 2008, Oxford University Press (OUP)

    Tim Corson

  37. Using expression profiling data to identify human microRNA targets

    Article • Nature Methods, November 2007, Springer Science + Business Media

    Tim Corson

  38. High Expression ofKIF14in Retinoblastoma: Association with Older Age at Diagnosis

    Article • Investigative Ophthalmology & Visual Science, November 2007, Association for Research in Vision and Ophthalmology (ARVO)

    Tim Corson

  39. Molecular Understanding and Modern Application of Traditional Medicines: Triumphs and Trials

    Article • Cell, September 2007, Elsevier

    Tim Corson

  40. KIF14 Messenger RNA Expression Is Independently Prognostic for Outcome in Lung Cancer

    Article • Clinical Cancer Research, June 2007, American Association for Cancer Research (AACR)

    Tim Corson

  41. One hit, two hits, three hits, more? Genomic changes in the development of retinoblastoma

    Article • Genes Chromosomes and Cancer, January 2007, Wiley

    Tim Corson

  42. Profiling genomic copy number changes in retinoblastoma beyond loss ofRB1

    Article • Genes Chromosomes and Cancer, January 2006, Wiley

    Tim Corson

  43. KIF14 mRNA expression is a predictor of grade and outcome in breast cancer

    Article • International Journal of Cancer, January 2006, Wiley

    Tim Corson

  44. Distinct patterns of expression of the RB gene family in mouse and human retina

    Article • Gene Expression Patterns, June 2005, Elsevier

    Tim Corson

  45. KIF14 is a candidate oncogene in the 1q minimal region of genomic gain in multiple cancers

    Article • Oncogene, May 2005, Springer Science + Business Media

    Tim Corson

  46. Cell-type specific regulation of calreticulin and Bcl-2 expression by mood stabilizer drugs

    Article • European Neuropsychopharmacology, March 2004, Elsevier

    Tim Corson

  47. Chronic Lithium Treatment Attenuates Intracellular Calcium Mobilization

    Article • Neuropsychopharmacology, February 2004, Springer Science + Business Media

    Tim Corson

  48. Association analysis of G-protein β3 subunit gene with altered Ca2+ homeostasis in bipolar disorder

    Article • Molecular Psychiatry, March 2001, Springer Science + Business Media

    Tim Corson