All Stories

  1. The APOBEC3 genes and their role in cancer: insights from human papillomavirus

    Article • Journal of Molecular Endocrinology, May 2019, Bioscientifica

    Tim Fenton

  2. Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair

    Article • Cancer Cell, March 2019, Elsevier

    Tim Fenton

  3. Author Correction: Chemosensitivity profiling of osteosarcoma tumour cell lines identifies a model of BRCAness

    Article • Scientific Reports, August 2018, Springer Science + Business Media

    Tim Fenton

  4. Pan-cancer deconvolution of tumour composition using DNA methylation

    Article • Nature Communications, August 2018, Springer Science + Business Media

    Tim Fenton

  5. Frequent HPV-independent p16/INK4A overexpression in head and neck cancer

    Article • Oral Oncology, August 2018, Elsevier

    Tim Fenton

  6. Chemosensitivity profiling of osteosarcoma tumour cell lines identifies a model of BRCAness

    Article • Scientific Reports, July 2018, Springer Science + Business Media

    Tim Fenton

  7. p53 controls expression of the DNA deaminase APOBEC3B to limit its potential mutagenic activity in cancer cells

    Article • Nucleic Acids Research, August 2017, Oxford University Press (OUP)

    Dr Simak Ali, Tim Fenton

  8. Human Papillomavirus Drives Tumor Development Throughout the Head and Neck: Improved Prognosis Is Associated With an Immune Response Largely Restricted to the Oropharynx

    Article • Journal of Clinical Oncology, December 2016, American Society of Clinical Oncology (ASCO)

    Tim Fenton

  9. CD8 + T cell response to human papillomavirus 16 E7 is able to predict survival outcome in oropharyngeal cancer

    Article • European Journal of Cancer, November 2016, Elsevier

    Tim Fenton

  10. CSN1 Somatic Mutations in Penile Squamous Cell Carcinoma

    Article • Cancer Research, June 2016, American Association for Cancer Research (AACR)

    Tim Fenton

  11. Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines

    Article • Cell Reports, March 2016, Elsevier

    Tim Fenton

  12. The Genomics, Epigenomics, and Transcriptomics of HPV-Associated Oropharyngeal Cancer—Understanding the Basis of a Rapidly Evolving Disease

    Article • January 2016, Elsevier

    Tim Fenton

  13. APOBEC3 genes: retroviral restriction factors to cancer drivers

    Article • Trends in Molecular Medicine, May 2015, Elsevier

    Tim Fenton

  14. APOBEC-Mediated Cytosine Deamination Links PIK3CA Helical Domain Mutations to Human Papillomavirus-Driven Tumor Development

    Article • Cell Reports, June 2014, Elsevier

    Tim Fenton

  15. Using high-density DNA methylation arrays to profile copy number alterations

    Article • Genome Biology, January 2014, Springer Science + Business Media

    Tim Fenton

  16. When defense turns into attack

    Article • Molecular & Cellular Oncology, January 2014, Taylor & Francis

    Tim Fenton

  17. Integrated virus-host methylome analysis in head and neck squamous cell carcinoma

    Article • Epigenetics, September 2013, Taylor & Francis

    Tim Fenton

  18. A Kinome-Wide RNAi Screen in Drosophila Glia Reveals That the RIO Kinases Mediate Cell Proliferation and Survival through TORC2-Akt Signaling in Glioblastoma

    Article • PLoS Genetics, February 2013, PLOS

    Tim Fenton

  19. Identification and functional validation of HPV-mediated hypermethylation in head and neck squamous cell carcinoma

    Article • Genome Medicine, January 2013, Springer Science + Business Media

    Tim Fenton

  20. Targeted next-generation sequencing of head and neck squamous cell carcinoma identifies novel genetic alterations in HPV+ and HPV- tumors

    Article • Genome Medicine, January 2013, Springer Science + Business Media

    Tim Fenton

  21. Resistance to EGF receptor inhibitors in glioblastoma mediated by phosphorylation of the PTEN tumor suppressor at tyrosine 240

    Article • Proceedings of the National Academy of Sciences, August 2012, Proceedings of the National Academy of Sciences

    Tim Fenton

  22. Phosphorylation of dedicator of cytokinesis 1 (Dock180) at tyrosine residue Y722 by Src family kinases mediates EGFRvIII-driven glioblastoma tumorigenesis

    Article • Proceedings of the National Academy of Sciences, February 2012, Proceedings of the National Academy of Sciences

    Tim Fenton

  23. Activation of Rac1 by Src-dependent phosphorylation of Dock180Y1811 mediates PDGFRα-stimulated glioma tumorigenesis in mice and humans

    Article • Journal of Clinical Investigation, December 2011, American Society for Clinical Investigation

    Tim Fenton

  24. Therapeutic targeting of epidermal growth factor receptor in human cancer: successes and limitations

    Article • Chinese Journal of Cancer, January 2011, Editorial Office of Chinese Journal of Cancer

    Tim Fenton

  25. Functions and regulation of the 70kDa ribosomal S6 kinases

    Article • The International Journal of Biochemistry & Cell Biology, January 2011, Elsevier

    Tim Fenton

  26. S6K1 is acetylated at lysine 516 in response to growth factor stimulation

    Article • Biochemical and Biophysical Research Communications, July 2010, Elsevier

    Tim Fenton

  27. Histone acetyltransferases interact with and acetylate p70 ribosomal S6 kinases in vitro and in vivo

    Article • The International Journal of Biochemistry & Cell Biology, February 2010, Elsevier

    Tim Fenton

  28. Regulation of ribosomal protein S6 kinases by ubiquitination

    Article • Biochemical and Biophysical Research Communications, May 2008, Elsevier

    Tim Fenton

  29. Malignant astrocytic glioma: genetics, biology, and paths to treatment

    Article • Genes & Development, November 2007, Cold Spring Harbor Laboratory Press

    Tim Fenton

  30. The PTEN and INK4A/ARF tumor suppressors maintain myelolymphoid homeostasis and cooperate to constrain histiocytic sarcoma development in humans

    Article • Cancer Cell, May 2006, Elsevier

    Tim Fenton

  31. Receptor association and tyrosine phosphorylation of S6 kinases

    Article • FEBS Journal, April 2006, Wiley

    Tim Fenton

  32. Subcellular Localization and Regulation of Coenzyme A Synthase

    Article • Journal of Biological Chemistry, September 2003, American Society for Biochemistry & Molecular Biology (ASBMB)

    Tim Fenton

  33. Protein Kinase C Phosphorylates Ribosomal Protein S6 Kinase βII and Regulates Its Subcellular Localization

    Article • Molecular and Cellular Biology, February 2003, ASM Journals

    Tim Fenton

  34. Molecular Cloning of CoA Synthase

    Article • Journal of Biological Chemistry, April 2002, American Society for Biochemistry & Molecular Biology (ASBMB)

    Tim Fenton

  35. A novel higher plant protein tyrosine phosphatase interacts with SNF1-related protein kinases via a KIS (kinase interaction sequence) domain

    Article • The Plant Journal, March 2002, Wiley

    Tim Fenton

  36. Oligomerization of G-protein-coupled Receptors Shown by Selective Co-immunoprecipitation

    Article • Journal of Biological Chemistry, February 2002, American Society for Biochemistry & Molecular Biology (ASBMB)

    Tim Fenton