All Stories

  1. Gene therapy and cost-effectiveness analysis: Current issues and future research
  2. Gene-Agnostic Therapeutic Strategies for Inherited Retinal Diseases: Neuroprotection and Immunomodulation
  3. Biological therapies at 25 years: from incremental advances to revolutionary transformations
  4. Thyroid eye disease: revolutionizing treatment with IGF-1 receptor targeted therapy
  5. Beyond the injection: delivery systems reshaping retinal disease management
  6. Autoimmune neuro-ophthalmic disorders: pathophysiologic mechanisms and targeted biologic therapies
  7. Suprachoroidal drug delivery: a versatile therapeutic platform
  8. Three-Year Clinical Outcomes in Geographic Atrophy: An Analysis of 18,712 Patient Eyes
  9. Long-acting delivery and therapies for neovascular age-related macular degeneration
  10. Safety and Tolerability of Suprachoroidal Axitinib, CLS-AX, for Neovascular AMD; Phase 1/2a Open-Label, Dose-Escalation Trial
  11. Gene Therapy for Non-Hereditary Retinal Disease: Age-Related Macular Degeneration, Diabetic Retinopathy, and Beyond
  12. Safety and Efficacy of CLS-TA by Anatomic Location of Inflammation: Results from the Phase 3 PEACHTREE Clinical Trial
  13. Effect of Race and Insurance Status on Treatment and Outcomes in Diabetic Retinopathy: Analysis of 43 274 Eyes Using the IRIS Registry
  14. The complement system: a novel therapeutic target for Age-related macular degeneration
  15. The evolving therapeutic landscape of diabetic retinopathy
  16. Optical coherence tomography outcomes as biomarkers for disease status, visual function, and prognosis in diabetic macular edema
  17. Aging Effects on Optic Nerve Neurodegeneration
  18. Triamcinolone Acetonide Suprachoroidal Injectable Suspension for Uveitic Macular Edema: Integrated Analysis of Two Phase 3 Studies
  19. Advancements in ocular gene therapy delivery: vectors and subretinal, intravitreal, and suprachoroidal techniques
  20. Progress in the pharmacotherapy of uveitis: the art of personalized care
  21. Longer-Term Anti-VEGF Therapy Outcomes in Neovascular Age-Related Macular Degeneration, Diabetic Macular Edema, and Vein Occlusion-Related Macular Edema
  22. A randomized, double-masked, multicenter trial of topical acrizanib (LHA510), a tyrosine kinase VEGF-receptor inhibitor, in treatment-experienced subjects with neovascular age-related macular degeneration
  23. Sustained release glaucoma therapies: Novel modalities for overcoming key treatment barriers associated with topical medications
  24. Disease Progression Pathways of Wet AMD: Opportunities for New Target Discovery
  25. Suprachoroidal CLS‐TA versus Rescue Therapies for the Treatment of Uveitic Macular Edema: A Post Hoc Analysis of PEACHTREE
  26. OCT Anatomic and Temporal Biomarkers in Uveitic Macular Edema
  27. Suprachoroidal CLS-TA with and without Systemic Corticosteroid and/or Steroid-Sparing Therapy: A Post-Hoc Analysis of the Phase 3 PEACHTREE Clinical Trial
  28. Genetics of Diabetic Retinopathy, a Leading Cause of Irreversible Blindness in the Industrialized World
  29. Glaucoma Heritability: Molecular Mechanisms of Disease
  30. Physics-based modeling of Age-related Macular Degeneration—A theoretical approach to quantify retinal and choroidal contributions to macular oxygenation
  31. Understanding the genetic pathology of Stargardt disease: a review of current findings and challenges
  32. Suprachoroidal Delivery of Small Molecules, Nanoparticles, Gene and Cell Therapies for Ocular Diseases
  33. Suprachoroidal CLS-TA for non-infectious uveitis: an open-label, safety trial (AZALEA)
  34. Biomechanics of suprachoroidal drug delivery: From benchtop to clinical investigation in ocular therapies
  35. Molecular Genetics of Glaucoma: Subtype and Ethnicity Considerations
  36. RNA Therapeutics for Retinal Diseases
  37. Visual acuity outcomes and anti-VEGF therapy intensity in macular oedema due to retinal vein occlusion: a real-world analysis of 15 613 patient eyes
  38. Microbial Spectrum and Antibacterial Susceptibility of Endophthalmitis Cultures in a Tertiary Referral Center in the Midwestern United States: An Analysis From 295 Patients
  39. Anti-Integrin therapy for retinovascular diseases
  40. Evolution of Primary Scleral Buckling Surgery: A Modified Lean Six Sigma Technique to Improve Surgical Efficiency
  41. Visual acuity outcomes and anti-VEGF therapy intensity in diabetic macular oedema: a real-world analysis of 28 658 patient eyes
  42. Suprachoroidal Delivery of Viral and Nonviral Gene Therapy for Retinal Diseases
  43. Retinal oximetry in glaucoma: investigations and findings reviewed
  44. Voretigene neparvovec-rzyl for treatment of RPE65-mediated inherited retinal diseases: a model for ocular gene therapy development
  45. Investigational plasma kallikrein inhibitors for the treatment of diabetic macular edema: an expert assessment
  46. Visual Acuity Outcomes and Anti–Vascular Endothelial Growth Factor Therapy Intensity in Neovascular Age-Related Macular Degeneration Patients
  47. Efficacy and Safety of Suprachoroidal CLS-TA for Macular Edema Secondary to Noninfectious Uveitis
  48. Current and upcoming anti-VEGF therapies and dosing strategies for the treatment of neovascular AMD: a comparative review
  49. Cost-effectiveness of Voretigene Neparvovec-rzyl vs Standard Care for RPE65-Mediated Inherited Retinal Disease
  50. Tie-2/Angiopoietin pathway modulation as a therapeutic strategy for retinal disease
  51. Important Considerations in Modeling the Cost-Effectiveness for the First Food and Drug Administration–Approved Gene Therapy and Implications for Future One-Time Therapies
  52. Efficacy and safety of bromfenac 0.075% formulated in DuraSite for pain and inflammation in cataract surgery
  53. Innovative therapies for neovascular age-related macular degeneration
  54. Vascular dysfunction in retinitis pigmentosa
  55. Complement inhibition as a therapeutic strategy in retinal disorders
  56. Estimation of impact of RPE65-mediated inherited retinal disease on quality of life and the potential benefits of gene therapy
  57. Pathological Consequences of Vascular Alterations in the Eye
  58. Vitreous Pathology
  59. Vitreous Physiology
  60. Real-world Outcomes of Anti–Vascular Endothelial Growth Factor Therapy in Diabetic Macular Edema in the United States
  61. Vital Dyes in Vitreomacular Surgery
  62. Stargardt macular dystrophy and evolving therapies
  63. Real-world Outcomes of Anti–Vascular Endothelial Growth Factor Therapy in Neovascular Age-Related Macular Degeneration in the United States
  64. The acute and chronic effects of intravitreal anti-vascular endothelial growth factor injections on intraocular pressure: A review
  65. Comparison of Monthly vs Treat-and-Extend Regimens for Individuals With Macular Edema Who Respond Well to Anti–Vascular Endothelial Growth Factor Medications
  66. Pharmacotherapy of retinal disease with visual cycle modulators
  67. Gene therapy for inherited retinal and optic nerve degenerations
  68. Treatment Burden in Neovascular AMD:Visual Acuity Outcomes are Associated With Anti-VEGF Injection Frequency
  69. Gene therapy for age-related macular degeneration
  70. Emerging vascular endothelial growth factor antagonists to treat neovascular age-related macular degeneration
  71. LEAN SIX SIGMA TECHNIQUES TO IMPROVE OPHTHALMOLOGY CLINIC EFFICIENCY
  72. Induced pluripotent stem cell-based therapy for age-related macular degeneration
  73. Dual Antagonism of PDGF and VEGF in Neovascular Age-Related Macular Degeneration
  74. EFFICACY OF DEXAMETHASONE INTRAVITREAL IMPLANT FOR REFRACTORY MACULAR EDEMA CAUSED BY RETINAL VEIN OCCLUSION
  75. RANIBIZUMAB FOR DIABETIC MACULAR EDEMA REFRACTORY TO MULTIPLE PRIOR TREATMENTS
  76. Angiographic Cystoid Macular Edema and Outcomes in the Comparison of Age-Related Macular Degeneration Treatments Trials
  77. Outcomes in Eyes with Retinal Angiomatous Proliferation in the Comparison of Age-Related Macular Degeneration Treatments Trials (CATT)
  78. Treatment strategies for refractory diabetic macular edema: switching anti-VEGF treatments, adopting corticosteroid-based treatments, and combination therapy
  79. Incidence, Risk Factors, and Timing of Elevated Intraocular Pressure After Intravitreal Triamcinolone Acetonide Injection for Macular Edema Secondary to Retinal Vein Occlusion
  80. Subretinal Hyperreflective Material in the Comparison of Age-Related Macular Degeneration Treatments Trials
  81. Influence of the Vitreomacular Interface on Treatment Outcomes in the Comparison of Age-Related Macular Degeneration Treatments Trials
  82. Outcomes of Eyes with Lesions Composed of >50% Blood in the Comparison of Age-Related Macular Degeneration Treatments Trials (CATT)
  83. Efficacy of Intravitreal Ocriplasmin for Treatment of Vitreomacular Adhesion
  84. Sustained Delivery Fluocinolone Acetonide Vitreous Implants
  85. Comparison of Optical Coherence Tomography Assessments in the Comparison of Age-Related Macular Degeneration Treatments Trials
  86. The Prevalence and Incidence of Epiretinal Membranes in Eyes With Inactive Extramacular CMV Retinitis
  87. Sporadic Visual Acuity Loss in the Comparison of Age-Related Macular Degeneration Treatments Trials (CATT)
  88. VEGFAandVEGFR2Gene Polymorphisms and Response to Anti–Vascular Endothelial Growth Factor Therapy
  89. Treatment of diabetic macular edema with sustained-release glucocorticoids: intravitreal triamcinolone acetonide, dexamethasone implant, and fluocinolone acetonide implant
  90. Factors affecting visual outcomes in patients with diabetic macular edema treated with ranibizumab
  91. Pazopanib eye drops: a randomised trial in neovascular age-related macular degeneration
  92. Dexamethasone Intravitreal Implant in Combination with Laser Photocoagulation for the Treatment of Diffuse Diabetic Macular Edema
  93. Macular Morphology and Visual Acuity in the Comparison of Age-related Macular Degeneration Treatments Trials
  94. Exploratory Analysis of the Effect of Intravitreal Ranibizumab or Triamcinolone on Worsening of Diabetic Retinopathy in a Randomized Clinical Trial
  95. Comparison of Treatment Regimens for Cytomegalovirus Retinitis in Patients with AIDS in the Era of Highly Active Antiretroviral Therapy
  96. Twelve-Month Efficacy and Safety of 0.5 mg or 2.0 mg Ranibizumab in Patients with Subfoveal Neovascular Age-related Macular Degeneration
  97. Aqueous Levels of Fluocinolone Acetonide after Administration of Fluocinolone Acetonide Inserts or Fluocinolone Acetonide Implants
  98. Ranibizumab for Edema of the Macula in Diabetes Study
  99. Non-cytomegalovirus Ocular Opportunistic Infections in Patients With Acquired Immunodeficiency Syndrome
  100. Ranibizumab Versus Photodynamic Therapy for Presumed Ocular Histoplasmosis Syndrome
  101. Baseline Predictors for One-Year Visual Outcomes with Ranibizumab or Bevacizumab for Neovascular Age-related Macular Degeneration
  102. Enzymatic Vitreolysis with Ocriplasmin for Vitreomacular Traction and Macular Holes
  103. Ranibizumab and Bevacizumab for Treatment of Neovascular Age-related Macular Degeneration
  104. Incidence of Cytomegalovirus Retinitis in the Era of Highly Active Antiretroviral Therapy
  105. Impaired ocular blood flow regulation in patients with open-angle glaucoma and diabetes
  106. Evaluation of the United States Public Health Service Guidelines for Discontinuation of Anticytomegalovirus Therapy After Immune Recovery in Patients With Cytomegalovirus Retinitis
  107. Changes in Vision- and Health-Related Quality of Life in Patients with Diabetic Macular Edema Treated with Pegaptanib Sodium or Sham
  108. Primary Endpoint Results of a Phase II Study of Vascular Endothelial Growth Factor Trap-Eye in Wet Age-related Macular Degeneration
  109. A Phase 2/3, Multicenter, Randomized, Double-Masked, 2-Year Trial of Pegaptanib Sodium for the Treatment of Diabetic Macular Edema
  110. Association of Host Genetic Risk Factors With the Course of Cytomegalovirus Retinitis in Patients Infected With Human Immunodeficiency Virus
  111. Ranibizumab and Bevacizumab for Neovascular Age-Related Macular Degeneration
  112. Patient preferences in the treatment of diabetic retinopathy
  113. Long-term Benefit of Sustained-Delivery Fluocinolone Acetonide Vitreous Inserts for Diabetic Macular Edema
  114. Ranibizumab for Choroidal Neovascularization Secondary to Causes Other Than Age-Related Macular Degeneration: A Phase I Clinical Trial
  115. Two-Year Outcomes of the Ranibizumab for Edema of the mAcula in Diabetes (READ-2) Study
  116. Excess Mortality in Patients with AIDS in the Era of Highly Active Antiretroviral Therapy: Temporal Changes and Risk Factors
  117. Sustained Ocular Delivery of Fluocinolone Acetonide by an Intravitreal Insert
  118. Response to: Combined treatment of intravitreal bevacizumab and intravitreal triamcinolone in patients with retinal vein occlusion by Schroff et al.,
  119. Diabetic macular oedema: physical, physiological and molecular factors contribute to this pathological process
  120. Combined treatment of intravitreal bevacizumab and intravitreal triamcinolone in patients with retinal vein occlusion: 6 months of follow-up
  121. INTRAVITREAL BEVACIZUMAB FOR CHOROIDAL NEOVASCULARIZATION SECONDARY TO PRESUMED OCULAR HISTOPLASMOSIS SYNDROME
  122. Anti-vascular endothelial growth factor therapy for neovascular ocular diseases other than age-related macular degeneration
  123. Antivascular endothelial growth factor therapy for neovascular age-related macular degeneration
  124. Age-related macular degeneration and the aging eye
  125. Therapeutic effects of ranibizumab in neovascular age-related macular degeneration
  126. How the diabetic eye loses vision
  127. The Relationship Between Retrobulbar and Choroidal Hemodynamics in Non-Neovascular Age-Related Macular Degeneration
  128. Squalamine lactate for the treatment of age-related macular degeneration
  129. Ranibizumab
  130. SUSTAINED RESPONSE TO MULTIPLE INTRAVITREAL TRIAMCINOLONE ACETONIDE INJECTIONS IN A PATIENT WITH PREDOMINANTLY OCCULT CHOROIDAL NEOVASCULARIZATION
  131. Ranibizumab Combined With Verteporfin Photodynamic Therapy in Neovascular Age-Related Macular Degeneration
  132. Corticosteroids as Antiangiogenic Agents
  133. Ranibizumab for Treatment of Neovascular Age-Related Macular Degeneration
  134. Retinal and Choroidal Blood Flow in Health and Disease
  135. ORAL ADMINISTRATION OF LUMIRACOXIB REDUCES CHOROIDAL NEOVASCULAR MEMBRANE DEVELOPMENT IN THE RAT LASER-TRAUMA MODEL
  136. HUMAN VITREOUS DISTRIBUTION OF LINEZOLID AFTER A SINGLE ORAL DOSE
  137. Anastomotic Vessels Remain Viable after Photodynamic Therapy in Primate Models of Choroidal Neovascularization
  138. Erratum
  139. New and classic insights into presumed ocular histoplasmosis syndrome and its treatment
  140. Current and future pharmacological intervention for diabetic retinopathy
  141. Future pharmacological treatment options for nonexudative and exudative age-related macular degeneration
  142. MV-6401, a potent photosensitizer: a review of the current state of photosensitizing agents for the treatment of exudative age-related macular degeneration
  143. Photodynamic therapy with PhotoPoint photosensitiser MV6401, indium chloride methyl pyropheophorbide, achieves selective closure of rat corneal neovascularisation and rabbit choriocapillaris
  144. Pharmacotherapy for diabetic retinopathy
  145. Macular pigment density and aging, assessed in the normal elderly and those with cataracts and age-related macular degeneration
  146. EVALUATION OF PHOTOPOINT PHOTOSENSITIZER MV6401, INDIUM CHLORIDE METHYL PYROPHEOPHORBIDE, AS A PHOTODYNAMIC THERAPY AGENT IN PRIMATE CHORIOCAPILLARIS AND LASER-INDUCED CHOROIDAL NEOVASCULARIZATION
  147. Corticosteroids in posterior segment disease: an update on new delivery systems and new indications
  148. Laser trabecular sclerosis for chronic hypotony after vitreoretinal surgery
  149. The Squirrel Monkey: Characterization of a New-World Primate Model of Experimental Choroidal Neovascularization and Comparison with the Macaque
  150. Diagnostic Imaging of Retinal Disease
  151. Current and Future Treatment Options for Nonexudative and Exudative Age-Related Macular Degeneration
  152. Squalamine Lactate Reduces Choroidal Neovascularization in a Laser-Injury Model in the Rat
  153. Diabetic Retinopathy and Diabetic Macular Edema: Pathophysiology, screening, and novel therapies
  154. Bacterial endophthalmitis prophylaxis
  155. Choroidal neovascular membrane inhibition in a laser treated rat model with intraocular sustained release triamcinolone acetonide microimplants
  156. The effects of dorzolamide on choroidal and retinal perfusion in non-exudative age related macular degeneration
  157. Leber congenital amaurosis associated with optic disk neovascularization and vitreous hemorrhage
  158. Recent advances in the treatment of exudative age-related macular degeneration, including transpupillary thermotherapy
  159. Proton therapy for exudative age-related macular degeneration: a randomized, sham-controlled clinical trial
  160. Ocular perfusion abnormalities in diabetes
  161. Novel approaches for retinal drug delivery
  162. An update on photodynamic therapy in age-related macular degeneration
  163. DIAGNOSTIC AND THERAPEUTIC CHALLENGES
  164. Intravitreal triamcinolone in subfoveal recurrence of choroidal neovascularisation after laser treatment in macular degeneration
  165. Choroidal perfusion perturbations in non-neovascular age related macular degeneration
  166. LOCALIZATION OF ROSE BENGAL, ALUMINUM PHTHALOCYANINE TETRASULFONATE, AND CHLORIN e6 IN THE RABBIT EYE
  167. Bacterial endophthalmitis prophylaxis for cataract surgery
  168. Presumed ocular histoplasmosis syndrome: update on epidemiology, pathogenesis, and photodynamic, antiangiogenic, and surgical therapies
  169. Relation between dietary intake, serum concentrations, and retinal concentrations of lutein and zeaxanthin in adults in a Midwest population
  170. Delayed suprachoroidal hemorrhage after glaucoma filtration procedures1 1The authors have no financial or proprietary interest in any aspect of this study.
  171. Evolving pathophysiological paradigms for age related macular degeneration
  172. Macular pigment optical density in a midwestern sample
  173. Ocular perfusion and age-related macular degeneration
  174. Intravitreal Triamcinolone Acetonide Inhibits Choroidal Neovascularization in a Laser-Treated Rat Model
  175. Anti-angiogenic therapy of proliferative diabetic retinopathy
  176. Potential therapeutic application of antisense oligonucleotides in the treatment of ocular diseases
  177. Changing therapeutic paradigms in CMV retinitis in AIDS
  178. Aging Affects the Retrobulbar Circulation Differently in Women and Men
  179. Endothelin-1-Mediated Retinal Artery Vasospasm and the Rabbit Electroretinogram
  180. MACULAR BUCKLING FOR RETINAL DETACHMENT DUE TO MACULAR HOLE IN HIGHLY MYOPIC EYES WITH POSTERIOR STAPHYLOMA
  181. Vasoprotection as neuroprotection for the optic nerve
  182. INTRAVITREAL TRIAMCINOLONE ACETONIDE IN EXUDATIVE AGE-RELATED MACULAR DEGENERATION
  183. Olestra Consumption Is Not Associated with Macular Pigment Optical Density in a Cross-Sectional Volunteer Sample in Indianapolis
  184. Update on acute and chronic endophthalmitis
  185. Changing therapeutic paradigms for exudative age-related macular degeneration: antiangiogenic agents and photodynamic therapy
  186. Corticosteroids as an Antiangiogenic Agent for Histoplasmosis-Related Subfoveal Choroidal Neovascularization
  187. Color Doppler imaging discloses reduced ocular blood flow velocities in nonexudative age-related macular degeneration
  188. Mitochondrial maculopathy: geographic atrophy of the macula in the MELAS associated A to G 3243 mitochondrial DNA point mutation
  189. Ginkgo biloba Extract Increases Ocular Blood Flow Velocity
  190. Progress in measurement of ocular blood flow and relevance to our understanding of glaucoma and age-related macular degeneration
  191. Comparison of intraocular to plasma HIV-1 viral burden in patients with cytomegalovirus retinitis
  192. Regulation of Retinal and Optic Nerve Blood Flow
  193. Age-Related Macular Degeneration
  194. THE USE OF DYE DILUTION CURVE ANALYSIS IN THE QUANTIFICATION OF INDOCYANINE GREEN ANGIOGRAMS OF THE HUMAN CHOROID
  195. Correspondence
  196. Repair of retinal detachments due to Herpes varicella-zoster virus retinitis
  197. Evolution of a full-thickness macular hole
  198. Radiation Therapy For Exudative Age-Related Macular Degeneration
  199. Talc Embolism: A Static Retinopathy
  200. Vascular Endothelial Growth Factor-Induced Retinal Permeability Is Mediated by Protein Kinase C In Vivo and Suppressed by an Orally Effective  -Isoform-Selective Inhibitor
  201. EXOGENOUS ASPERGILLUS NIGER ENDOPHTHALMITIS IN A PATIENT WITH A FILTERING BLEB
  202. Surgical Treatment of a Macular Hole Secondary to Accidental Laser Burn
  203. Blebitis, Early EndophthalmitS, and Late Endophthalmitis after Glaucoma-filtering Surgery
  204. Uveal lymphoid neoplasia: A clinical-pathologic correlation and review of the early form
  205. Subretinal Aspiration Biopsy of Ocular Lymphoma
  206. Acute Progressive Multifocal Best's Disease in a 61 -year-old Man
  207. Postvitrectomy Positioning Complicated by Ulnar Nerve Palsy
  208. Ocular Antimicrobial Therapy
  209. Endophthalmitis Following Glaucoma Filtering Surgery
  210. INTRAVITREAL TOXICITY OF DENTAL ADHESIVES IN THE RABBIT
  211. Serpiginous Choroiditis
  212. SEVERE PENETRATING EYE TRAUMA CAUSED BY FISH PICK ACCIDENTS
  213. Herpes Simplex Virus Corneal Dendrite
  214. Vitreous amyloidosis in familial amyloidotic polyneuropathy. Report of a case with the Val30Met transthyretin mutation
  215. Laser photodisruption of visible retinal artery emboli.
  216. Retinal artery occlusion in rabbit eyes using human atheroma
  217. Seronegative myasthenia gravis: A plasma factor inhibiting agonist-induced acetylcholine receptor function copurifies with IgM
  218. A susceptibility locus for multiple sclerosis is linked to the T cell receptor β chain complex
  219. PHOTOSENSITIZATION OF SINGLE-STRAND BREAKS IN pBR322 DNA BY ROSE BENGAL
  220. A simple method for DNA purification from peripheral blood
  221. Molecular Genotypes of the T-Cell Receptor Beta Chain in Families with Multiple Sclerosis
  222. PHOTOADDITION OF CHLORPROMAZINE TO GUANOSINE-5'-MONOPHOSPHATE