All Stories

  1. Redox signaling-mediated S-glutathionylation of protein disulfide isomerase A1 initiates intrinsic apoptosis and contributes to accelerated aging

    Article • Redox Biology, September 2025, Elsevier

    Dr Theodore Lemuel Mathuram

  2. Kinase Drug Discovery: An Artificial Intelligence Revolution

    Article • AI in Precision Oncology, April 2025, Mary Ann Liebert Inc

    Dr Theodore Lemuel Mathuram

  3. Life in the Algo “Rhythm”: Redefining Human Medicine

    Article • AI in Precision Oncology, December 2024, Mary Ann Liebert Inc

    Dr Theodore Lemuel Mathuram

  4. GSK-3: An “Ace” Among Kinases

    Article • Cancer Biotherapy & Radiopharmaceuticals, May 2024, Mary Ann Liebert Inc

    Dr Theodore Lemuel Mathuram

  5. Mitochondrial ncRNA LDL-805 declines in alveolar epithelial type 2 cells of chronic obstructive pulmonary disease patients

    Article • January 2024, Cold Spring Harbor Laboratory Press

    Dr Theodore Lemuel Mathuram

  6. Importance of Functional Foods Against Aging of Adult Stem Cells

    Article • January 2023, Springer Science + Business Media

    Dr Theodore Lemuel Mathuram

  7. REV-ERB is essential in cardiac fibroblasts homeostasis

    Article • Frontiers in Pharmacology, October 2022, Frontiers

    Dr Theodore Lemuel Mathuram

  8. Synthetic Oligos Derived from mtDNA-Encoded Non-Coding RNAs as Potential Therapeutic Agents in Restoration of Mitochondrial Bioenergetics

    Article • May 2022, American Thoracic Society

    Dr Theodore Lemuel Mathuram

  9. A Synthetic Small RNA Homologous to the D-Loop Transcript of mtDNA Enhances Mitochondrial Bioenergetics

    Article • Frontiers in Physiology, April 2022, Frontiers

    Dr Theodore Lemuel Mathuram

  10. Smoke Associated Changes in AET2 Cell Mitochondrial Small RNAs Transcriptome

    Article • May 2021, American Thoracic Society

    Dr Theodore Lemuel Mathuram

  11. Abstract 3657: Analysis of the regulation of PD-L1 expression and methyl transferases levels following inhibition of histone deacetylases in cancer cells

    Article • Cancer Research, August 2020, American Association for Cancer Research (AACR)

    Dr Theodore Lemuel Mathuram

  12. The apoptotic effect of GSK-3 inhibitors: BIO and CHIR 98014 on H1975 lung cancer cells through ROS generation and mitochondrial dysfunction

    Article • Biotechnology Letters, March 2020, Springer Science + Business Media

    Dr Theodore Lemuel Mathuram

  13. Abstract 666: Determination of biomarkers for neuronal damage in bortezomib (BTZ) induced peripheral neuropathy (BIPN)

    Article • Cancer Research, July 2019, American Association for Cancer Research (AACR)

    Dr Theodore Lemuel Mathuram

  14. GSK-3 Inhibitors: A Double-Edged Sword? – An Update on Tideglusib

    Article • Drug Research, January 2018, Thieme Publishing Group

    Dr Theodore Lemuel Mathuram

  15. Copper oxide nanoparticles induce anticancer activity in A549 lung cancer cells by inhibition of histone deacetylase

    Article • Biotechnology Letters, November 2017, Springer Science + Business Media

    Dr Theodore Lemuel Mathuram

  16. Correlative Studies Unravelling the Possible Mechanism of Cell Death in Tideglusib-Treated Human Ovarian Teratocarcinoma-Derived PA-1 Cells

    Article • Journal of Environmental Pathology Toxicology and Oncology, January 2017, Begell House

    Dr Theodore Lemuel Mathuram, Dr Changam Sheela Sasikumar

  17. Tideglusib induces apoptosis in human neuroblastoma IMR32 cells, provoking sub-G 0 /G 1 accumulation and ROS generation

    Article • Environmental Toxicology and Pharmacology, September 2016, Elsevier

    Dr Theodore Lemuel Mathuram, Dr Changam Sheela Sasikumar