All Stories

  1. Metabolic alterations and redox homeostasis in ferroptosis: emerging mechanisms and therapeutic implications
  2. Synthesis and antiproliferative activity of new pseudo-C-nucleosides with pyrazole and tetrazole aglycons and a functionalized xylofuranose scaffold
  3. Repurposing Rilmenidine as a Potential Antimetastatic Therapy Targeting Nischarin in Pancreatic Ductal Adenocarcinoma
  4. Computational Design, Synthesis, and In Vitro Evaluation of Novel Piperazine-Based HDAC Inhibitors as Potential Breast Cancer Therapeutics
  5. The Landscape of Ferroptosis-Related Gene Signatures as Molecular Stratification in Triple-Negative Breast Cancer
  6. Platelet transfusion refractoriness in patients with acute myeloid leukemia: The role of anti-platelet antibodies
  7. Identification of a Novel miR-122-5p/CDC25A Axis and Potential Therapeutic Targets for Chronic Myeloid Leukemia
  8. Nischarin agonist rilmenidine shows antimetastatic potential in pancreatic ductal adenocarcinoma
  9. Redox-dependent metabolic alterations underlying chemosensitivity in HL-60 and K562 leukemia cells
  10. Unveiling the 4-aminoquinoline derivatives as potent agents against pancreatic ductal adenocarcinoma (PDAC) cell lines
  11. Screening Algal and Cyanobacterial Extracts to Identify Potential Substitutes for Fetal Bovine Serum in Cellular Meat Cultivation
  12. Development of Novel ROCK Inhibitors via 3D-QSAR and Molecular Docking Studies: A Framework for Multi-Target Drug Design
  13. DEVELOPMENT OF AN INTEGRATIVE PLATFORM FOR DESIGN OF NOVEL SIRT2 INHIBITORS
  14. Quinoline‐based thiazolyl‐hydrazones target cancer cells through autophagy inhibition
  15. Nischarin expression may have differing roles in male and female melanoma patients
  16. Correlating Basal Gene Expression across Chemical Sensitivity Data to Screen for Novel Synergistic Interactors of HDAC Inhibitors in Pancreatic Carcinoma
  17. Synthesis, characterization, andin vivoevaluation of the anticancer activity of a series of 5- and 6-(halomethyl)-2,2′-bipyridine rhenium tricarbonyl complexes
  18. Synthesis, characterization, and in vivo evaluation of the anticancer activity of a series of 5- and 6-(halomethyl)-2,2'-bipyridine rhenium tricarbonyl complexes.
  19. Discovery of 1-Benzhydryl-Piperazine-Based HDAC Inhibitors with Anti-Breast Cancer Activity: Synthesis, Molecular Modeling, In Vitro and In Vivo Biological Evaluation
  20. Correlating basal gene expression across chemical sensitivity data to screen for novel synergistic interactors of HDAC inhibitors in pancreatic carcinoma
  21. Cationic amphiphilic drugs as potential anticancer therapy for PDAC
  22. The Effects of Resveratrol-Rich Extracts of Vitis vinifera Pruning Waste on HeLa, MCF-7 and MRC-5 Cells: Apoptosis, Autophagia and Necrosis Interplay
  23. Increased circulating TGF-β1 is associated with impairment in NK cell effector functions in metastatic melanoma patients
  24. Nischarin expression may have differing roles in male and female melanoma patients
  25. Expanding the Accessible Chemical Space of SIRT2 Inhibitors through Exploration of Binding Pocket Dynamics
  26. Discovery of 1-benzhydryl piperazine-based HDAC inhibitors with anticancer and antimetastatic properties against human breast cancer: synthesis, molecular modeling, in vitro and in vivo biological evaluation
  27. Targeting Histone Deacetylases: Opportunities for Cancer Treatment and Chemoprevention
  28. Antibody VH domain sequence analysis by a bioinformatics approach based on electronic amino acid properties may help to predict paratop location
  29. In Vitro Study of Two Edible Polygonoideae Plants: Phenolic Profile, Cytotoxicity, and Modulation of Keap1-Nrf2 Gene Expression
  30. A Model for Potential B-cell Precursors of Broadly Neutralizing HIV-1 Antibodies Selection and Antibody Affinity Maturation
  31. Telmisartan induces melanoma cell apoptosis and synergizes with vemurafenib in vitro by altering cell bioenergetics
  32. Author Correction: Iscador Qu inhibits doxorubicin-induced senescence of MCF7 cells
  33. Antibody Epitope Specificity for dsDNA Phosphate Backbone Is an Intrinsic Property of the Heavy Chain Variable Germline Gene Segment Used
  34. Benzothiazole carbamates and amides as antiproliferative species
  35. Conformationally restricted goniofufurone mimics with halogen, azido or benzoyloxy groups at the C-7 position: Design, synthesis and antiproliferative activity
  36. Cooperation of intrathymic T15 idiotype-bearing B and complementary T cells in ontogeny of natural Treg cells involved in establishment of T15 clonal dominance
  37. PO-258 Telmisartan induces melanoma cell apoptosis via generation of ros and has synergistic effects with targeted therapyin vitro
  38. Chemical characterization, antioxidant, genotoxic and in vitro cytotoxic activity assessment of Juniperus communis var. saxatilis
  39. Evaluation of anticancer and antimicrobial activities of the Polygonum maritimum ethanol extract
  40. Novel O-methyl goniofufurone and 7-epi-goniofufurone derivatives: synthesis, in vitro cytotoxicity and SAR analysis
  41. IL-2 Mediated Improvement of Cell Antitumor Activity in Advanced Breast Cancer Patients
  42. Targeted therapy and personalized medicine in hepatocellular carcinoma: drug resistance, mechanisms, and treatment strategies
  43. Synthesis and in vitro antitumour activity of crassalactone D, its stereoisomers and novel cinnamic ester derivatives
  44. Iscador Qu inhibits doxorubicin-induced senescence of MCF7 cells
  45. The absence of immunoreactivity to donkey’s milk in patients with recurrent aphthous ulcers and immunoreactivity to cow’s milk
  46. Design, synthesis and in vitro antitumour activity of new goniofufurone and 7- epi -goniofufurone mimics with halogen or azido groups at the C-7 position
  47. A combined ligand- and structure-based approach for the identification of rilmenidine-derived compounds which synergize the antitumor effects of doxorubicin
  48. Synthesis of the vitamin E amino acid esters with an enhanced anticancer activity and in silico screening for new antineoplastic drugs
  49. In vitro assessment of antiproliferative action selectivity of dietary isothiocyanates for tumor versus normal human cells
  50. Antioxidants: Role on Health and Prevention
  51. Rilmenidine suppresses proliferation and promotes apoptosis via the mitochondrial pathway in human leukemic K562 cells
  52. Synthesis and antiproliferative activity of goniobutenolides A and B, 5-halogenated crassalactone D derivatives and the corresponding 7-epimers
  53. Sensitization of K562 Leukemia Cells to Doxorubicin by theViscum albumExtract
  54. Decreased expression of pSTAT, IRF-1 and DAP10 signalling molecules in peripheral blood lymphocytes of patients with metastatic melanoma
  55. Acute Effects of Black Currant Consumption on Salivary Flow Rate and Secretion Rate of Salivary Immunoglobulin A in Healthy Smokers
  56. P4.09 * Role of Caspase-3 during TNF-alpha induced membrane molecule shedding from K-562 cells
  57. Effects of mistletoe extract on markers of platelet activation and aggregation
  58. Novel Selenosemicarbazone Metal Complexes Exert Anti-tumor Effect via Alternative, Caspase-independent Necroptotic Cell Death
  59. PO117 IMPAIRMENT OF IFN GAMMA PRODUCTION AND NK CELL CYTOTOXICITY OF ADVANCED BREAST CANCER PATIENTS
  60. Effects of bioactive‐rich extracts of pomegranate, persimmon, nettle, dill, kale and Sideritis and isolated bioactives on arachidonic acid induced markers of platelet activation and aggregation
  61. Phosphocholine-binding antibody activities are hierarchically encoded in the sequence of the heavy-chain variable region: dominance of self-association activity in the T15 idiotype
  62. Imidazoline-1 Receptor Ligands as Apoptotic Agents: Pharmacophore Modeling and Virtual Docking Study
  63. STAT Transcription Factors in Tumor Development and Targeted Therapy of Malignancies
  64. Biological evaluation of transdichloridoplatinum( II) complexes with 3- and 4-acetylpyridine in comparison to cisplatin
  65. Cell cycle analysis in patients with Fanconi anemia from Serbia
  66. Biological activity of Aronia melanocarpa antioxidants pre-screening in intervention study design
  67. Specific Binding of Paraprotein to Platelet Receptors as a Cause of Platelet Dysfunction in Monoclonal Gammopathies
  68. Anti-metastatic and Anti-angiogenic Properties of Potential New Anti-cancer Drugs Based on Metal Complexes of Selenosemicarbazones
  69. 105 In Vitro Evaluation of Antioxidant and Antitumoral Activities of Marine Algae Gelidium Sesquipedale and Fucus Spiralis
  70. Actinidin, a protease from kiwifruit, induces changes in morphology and adhesion of T84 intestinal epithelial cells
  71. Naturally occurring V region connected antibodies inhibit anti-dsDNA antibody reactivity with dsDNA
  72. PS2-076 TNF alpha mediated shadding of CD30 AND CD45 Kfrom -562 cells without caspase-3 activation
  73. Synthesis, characterization, cytotoxic activity and DNA binding properties of the novel dinuclear cobalt(III) complex with the condensation product of 2-acetylpyridine and malonic acid dihydrazide
  74. Non-substituted N-heteroaromatic selenosemicarbazone metal complexes induce apoptosis in cancer cells via activation of mitochondrial pathway
  75. Serum DPPIV activity and CD26 expression on lymphocytes in patients with benign or malignant breast tumors
  76. TNF-α Induced Apoptosis is Accompanied with Rapid CD30 and Slower CD45 Shedding from K-562 Cells
  77. PS3-33 Dose and time depending effects of TNF-α on shedding of CD45 and CD30 from K-562 cells
  78. Synthesis, structure and characterization of novel Cd(II) and Zn(II) complexes with the condensation product of 2-formylpyridine and selenosemicarbazide
  79. Immunoglobulin G-Reactive Antibodies from Sera of Healthy Individuals Enriched in IgG2 - Therapeutic Potential in HIV-1 Infection
  80. Characteristics of novel myeloid precursor cell line, PC-MDS, established from a bone marrow of the patient with therapy-related myelodysplastic syndrome
  81. Clinical stage-depending decrease of NK cell activity in multiple myeloma patients
  82. Anti-IgG Antibodies from Sera of Healthy Individuals Neutralize HIV-1 Primary Isolates.
  83. Synthesis and characterization of a novel Pd(II) complex with the condensation product of 2-(diphenylphosphino)benzaldehyde and ethyl hydrazinoacetate. Cytotoxic activity of the synthesized complex and related Pd(II) and Pt(II) complexes
  84. Effect of TNF-α on Raji cells at different cellular levels estimated by various methods
  85. Modulation of TNF-α activity in tumor PC cells using anti-CD45 and anti-CD95 monoclonal antibodies
  86. Growth Effects of Some Platinum(II) Complexes with Sulfur-Containing Carrier Ligands on MCF7 Human Breast Cancer Cell Line upon Simultaneous Administration with Taxol
  87. In-vitro TNF-α effects on hematopoietic cell lines
  88. Human Immunodeficiency Virus V3 Peptide-Reactive Antibodies Are Present in Normal HIV-Negative Sera