All Stories

  1. Host-directed antiviral strategy targeting prohibitins: Mel56 suppresses influenza A virus and severe acute respiratory syndrome coronavirus 2 via modulation of antioxidant pathways and mitochondrial function

    Article • Microbiology Spectrum, May 2026, ASM Journals

    Takashi Kuzuhara

  2. Glycan-binding properties of SARS-CoV-2 spike proteins: interactions with aminoglycoside antibiotics

    Article • Scientific Reports, March 2026, Springer Science + Business Media

    Takashi Kuzuhara

  3. Pharmacophores of Influenza Virus PA Endonuclease Inhibitors

    Article • January 2026, Springer Science + Business Media

    Takashi Kuzuhara

  4. Triethylamine inhibits influenza A virus infection and growth via mechanisms independent of viral neuraminidase and RNA-dependent RNA polymerase

    Article • PLOS One, August 2025, PLOS

    Takashi Kuzuhara

  5. Anacardic Acid Derivatives Isolated from Fungal Species <i>Tyromyces fissilis</i> as New Histone Acetyltransferase Inhibitors

    Article • Biological and Pharmaceutical Bulletin, December 2024, Pharmaceutical Society of Japan

    Takashi Kuzuhara

  6. Possible involvement of zinc transporter ZIP13 in myogenic differentiation

    Article • Scientific Reports, April 2024, Springer Science + Business Media

    Takashi Kuzuhara

  7. Bakuchiol targets mitochondrial proteins, prohibitins and voltage-dependent anion channels: New insights into developing antiviral agents

    Article • Journal of Biological Chemistry, February 2024, Elsevier

    Takashi Kuzuhara

  8. Molecular and functional characterization of an evolutionarily conserved CREB ‐binding protein in the Lymnaea CNS

    Article • The FASEB Journal, October 2022, Wiley

    Takashi Kuzuhara

  9. Acetylation of the influenza A virus polymerase subunit PA in the N‐terminal domain positively regulates its endonuclease activity

    Article • FEBS Journal, July 2021, Wiley

    Takashi Kuzuhara

  10. In-vitro acetylation of SARS-CoV and SARS-CoV-2 nucleocapsid proteins by human PCAF and GCN5

    Article • Biochemical and Biophysical Research Communications, June 2021, Elsevier

    Takashi Kuzuhara

  11. Organic synthesis and anti-influenza A virus activity of cyclobakuchiols A, B, C, and D

    Article • PLOS One, March 2021, PLOS

    Takashi Kuzuhara

  12. A novel aqueous extract from rice fermented with Aspergillus oryzae and Saccharomyces cerevisiae possesses an anti-influenza A virus activity

    Article • PLOS One, January 2021, PLOS

    Takashi Kuzuhara

  13. Jiadifenolide induces the expression of cellular communication network factor (CCN) genes, and CCN2 exhibits neurotrophic activity in neuronal precursor cells derived from human induced pluripotent stem cells

    Article • Biochemical and Biophysical Research Communications, November 2019, Elsevier

    Takashi Kuzuhara

  14. Acetylation of lysine residues in the recombinant nucleoprotein and VP40 matrix protein of Zaire Ebolavirus by eukaryotic histone acetyltransferases

    Article • Biochemical and Biophysical Research Communications, October 2018, Elsevier

    Takashi Kuzuhara

  15. Different murine-derived feeder cells alter the definitive endoderm differentiation of human induced pluripotent stem cells

    Article • PLOS One, July 2018, PLOS

    Takashi Kuzuhara

  16. MAO-A Inhibitory Potential of Terpene Constituents from Ginger Rhizomes—A Bioactivity Guided Fractionation

    Article • Molecules, May 2018, MDPI AG

    Takashi Kuzuhara

  17. Influenza A virus nucleoprotein is acetylated by histone acetyltransferases PCAF and GCN5

    Article • Journal of Biological Chemistry, May 2018, Elsevier

    Takashi Kuzuhara

  18. NMR spectra of PB2 627, the RNA-binding domain in influenza A virus RNA polymerase that contains the pathogenicity factor lysine 627, and improvement of the spectra by small osmolytes

    Article • Biochemistry and Biophysics Reports, December 2017, Elsevier

    Professor Masaru Tanokura, Takashi Kuzuhara

  19. Anti-influenza virus activity of extracts from the stems of Jatropha multifida Linn. collected in Myanmar

    Article • BMC Complementary and Alternative Medicine, February 2017, Springer Science + Business Media

    Takashi Kuzuhara

  20. Neurotrophic activity of jiadifenolide on neuronal precursor cells derived from human induced pluripotent stem cells

    Article • Biochemical and Biophysical Research Communications, February 2016, Elsevier

    Takashi Kuzuhara

  21. Inhibition of PA endonuclease activity of influenza virus RNA polymerase by Kampo medicines

    Article • Drug Discoveries & Therapeutics, January 2016, International Research and Cooperation Association for Bio & Socio-Sciences Advancement (IRCA-BSSA)

    Takashi Kuzuhara

  22. Bakuchiol Is a Phenolic Isoprenoid with Novel Enantiomer-selective Anti-influenza A Virus Activity Involving Nrf2 Activation

    Article • Journal of Biological Chemistry, November 2015, Elsevier

    Takashi Kuzuhara

  23. A Novel Functional Site in the PB2 Subunit of Influenza A Virus Essential for Acetyl-CoA Interaction, RNA Polymerase Activity, and Viral Replication

    Article • Journal of Biological Chemistry, September 2014, Elsevier

    Takashi Kuzuhara

  24. Suppression of increased blood glucose levels in mice by Awa-ban tea following oral administration of mono- and disaccharides

    Article • Journal of Functional Foods, May 2014, Elsevier

    Takashi Kuzuhara

  25. Conformational Polymorphism of m7GTP in Crystal Structure of the PB2 Middle Domain from Human Influenza A Virus

    Article • PLOS One, November 2013, PLOS

    Takashi Kuzuhara

  26. Identification and purification of resorcinol, an antioxidant specific to Awa-ban (pickled and anaerobically fermented) tea

    Article • Food Research International, November 2013, Elsevier

    Takashi Kuzuhara

  27. Anti-Influenza Activity of C60 Fullerene Derivatives

    Article • PLOS One, June 2013, PLOS

    Takashi Kuzuhara

  28. Inhibition of MAO‐A and stimulation of behavioural activities in mice by the inactive prodrug form of the anti‐influenza agent oseltamivir

    Article • British Journal of Pharmacology, April 2013, Wiley

    Takashi Kuzuhara

  29. Epigenetic Regulation of Gene Expression in the Nervous System

    Article • January 2013, Springer Science + Business Media

    Takashi Kuzuhara

  30. Structural basis for theHelicobacter pyloricarcinogenic TNF〈-inducing protein

    Article • Acta Crystallographica Section A Foundations of Crystallography, August 2011, International Union of Crystallography

    Takashi Kuzuhara

  31. Anti-Influenza Activity of Marchantins, Macrocyclic Bisbibenzyls Contained in Liverworts

    Article • PLOS One, May 2011, PLOS

    Takashi Kuzuhara

  32. Bioactivity guided isolation of anticancer constituents from leaves of Alnus sieboldiana (Betulaceae)

    Article • Phytomedicine, April 2011, Elsevier

    Dr Agnieszka Ludwiczuk, Takashi Kuzuhara

  33. New Role of (−)-Epicatechin in Enhancing the Induction of Growth Inhibition and Apoptosis in Human Lung Cancer Cells by Curcumin

    Article • Cancer Prevention Research, August 2010, American Association for Cancer Research (AACR)

    Takashi Kuzuhara

  34. Anti-influenza activity of phenethylphenylphthalimide analogs derived from thalidomide

    Article • Bioorganic & Medicinal Chemistry, July 2010, Elsevier

    Takashi Kuzuhara

  35. Design and Synthesis of Resin-Conjugated Tamiflu Analogs for Affinity Chromatography

    Article • Bulletin of the Korean Chemical Society, March 2010, Korean Chemical Society

    Takashi Kuzuhara

  36. Apoptosis of Human Lung Cancer Cells by Curcumin Mediated through Up-Regulation of "Growth Arrest and DNA Damage Inducible Genes 45 and 153"

    Article • Biological and Pharmaceutical Bulletin, January 2010, Pharmaceutical Society of Japan

    Takashi Kuzuhara

  37. Green tea catechins inhibit the endonuclease activity of influenza A virus RNA polymerase

    Article • PLoS Currents, October 2009, PLOS

    Takashi Kuzuhara

  38. Structural basis for the Helicobacter pylori-carcinogenic TNF-α-inducing protein

    Article • Biochemical and Biophysical Research Communications, October 2009, Elsevier

    Takashi Kuzuhara

  39. Design and synthesis of immobilized Tamiflu analog on resin for affinity chromatography

    Article • Tetrahedron Letters, July 2009, Elsevier

    Takashi Kuzuhara

  40. Structural Basis of the Influenza A Virus RNA Polymerase PB2 RNA-binding Domain Containing the Pathogenicity-determinant Lysine 627 Residue

    Article • Journal of Biological Chemistry, March 2009, Elsevier

    Takashi Kuzuhara

  41. Crystallization and X-ray diffraction analysis of the RNA primer/promoter-binding domain of influenza A virus RNA-dependent RNA polymerase PB2

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, January 2009, International Union of Crystallography

    Takashi Kuzuhara

  42. TNF‐α‐inducing protein, a carcinogenic factor secreted from H. pylori , enters gastric cancer cells

    Article • International Journal of Cancer, April 2008, Wiley

    Takashi Kuzuhara

  43. Green tea catechin as a chemical chaperone in cancer prevention

    Article • Cancer Letters, March 2008, Elsevier

    Takashi Kuzuhara

  44. Generation of Mouse Monoclonal Antibody against (-)-Epigallocatechin Gallate

    Article • Biological and Pharmaceutical Bulletin, January 2008, Pharmaceutical Society of Japan

    Takashi Kuzuhara

  45. DNA-binding activity of TNF-α inducing protein from Helicobacter pylori

    Article • Biochemical and Biophysical Research Communications, November 2007, Elsevier

    Takashi Kuzuhara

  46. Synergistic effects of multiple treatments, and both DNA and RNA direct bindings on, green tea catechins

    Article • Molecular Carcinogenesis, April 2007, Wiley

    Takashi Kuzuhara

  47. Helicobacter pylori-secreting protein Tipα is a potent inducer of chemokine gene expressions in stomach cancer cells

    Article • Journal of Cancer Research and Clinical Oncology, November 2006, Springer Science + Business Media

    Takashi Kuzuhara

  48. DNA and RNA as New Binding Targets of Green Tea Catechins

    Article • Journal of Biological Chemistry, June 2006, Elsevier

    Takashi Kuzuhara

  49. Carcinogenic Role of Tumor Necrosis Factor-α Inducing Protein of Helicobacter pylori in Human Stomach

    Article • BMB Reports, January 2006, Korean Society for Biochemistry and Molecular Biology - BMB Reports

    Takashi Kuzuhara

  50. Presence of a Motif Conserved between Helicobacter pylori TNF-.ALPHA. Inducing Protein (Tip.ALPHA.) and Penicillin-Binding Proteins

    Article • Biological and Pharmaceutical Bulletin, January 2005, Pharmaceutical Society of Japan

    Takashi Kuzuhara

  51. The Crystal Structure of CCG1/TAFII250-interacting Factor B (CIB)

    Article • Journal of Biological Chemistry, March 2004, Elsevier

    Takashi Kuzuhara

  52. A nuclear FK506-binding protein is a histone chaperone regulating rDNA silencing

    Article • Nature Structural & Molecular Biology, February 2004, Springer Science + Business Media

    Takashi Kuzuhara

  53. Crystal structure analysis of human CCG1/TAFII250-interacting factor B (CIB)

    Article • Acta Crystallographica Section A Foundations of Crystallography, August 2002, International Union of Crystallography

    Takashi Kuzuhara

  54. Identification and characterization of CIA/ASF1 as an interactor of bromodomains associated with TFIID

    Article • Proceedings of the National Academy of Sciences, July 2002, Proceedings of the National Academy of Sciences

    Takashi Kuzuhara

  55. Crystallization of human CCG1-interacting factor B (CIB)

    Article • Journal of Crystal Growth, November 2001, Elsevier

    Takashi Kuzuhara

  56. Purification, crystallization and preliminary X-ray crystallographic analysis of human CCG1-interacting factor B

    Article • Acta Crystallographica Section D Biological Crystallography, November 2000, International Union of Crystallography

    Takashi Kuzuhara

  57. Functional interaction of general transcription initiation factor TFIIE with general chromatin factor SPT16/CDC68

    Article • Genes to Cells, April 2000, Wiley

    Takashi Kuzuhara

  58. A human homologue of yeast anti‐silencing factor has histone chaperone activity

    Article • Genes to Cells, March 2000, Wiley

    Takashi Kuzuhara

  59. Relationship between the Subcellular Localization and Structures of Catalytic Domains of FKBP-Type PPIases

    Article • The Journal of Biochemistry, November 1999, Oxford University Press (OUP)

    Takashi Kuzuhara

  60. Isolation and Characterization of a cDNA Encoding a Human TFIID Subunit Containing a Variety of Putative Structural Motifs Including Direct Repeats.

    Article • Biological and Pharmaceutical Bulletin, January 1996, Pharmaceutical Society of Japan

    Takashi Kuzuhara

  61. The sequence of a Xenopus laevis TFIID subunit reveals remarkable conservation among vertebrates

    Article • Gene, October 1995, Elsevier

    Takashi Kuzuhara

  62. Heterogeneity and Tissue-Specific Expression of Eukaryotic Transcription Factor S-II-Related Protein mRNA1

    Article • The Journal of Biochemistry, May 1991, Oxford University Press (OUP)

    Takashi Kuzuhara

  63. 1H nuclear magnetic resonance study of the solution conformation of an antibacterial protein, sapecin

    Article • FEBS Letters, September 1990, Wiley

    Takashi Kuzuhara

  64. Determination of the Disulfide Array in Sapecin, an Antibacterial Peptide of Sarcophaga peregrina (Flesh Fly)1

    Article • The Journal of Biochemistry, April 1990, Oxford University Press (OUP)

    Takashi Kuzuhara