All Stories

  1. Autonomous adaptive optimization of NMR experimental conditions for precise inference of minor conformational states of proteins based on chemical exchange saturation transfer

    Article • PLOS One, May 2025, PLOS

    Takanori Kigawa

  2. Molecular mechanism of glycolytic flux control intrinsic to human phosphoglycerate kinase

    Article • Proceedings of the National Academy of Sciences, December 2021, Proceedings of the National Academy of Sciences

    Takanori Kigawa

  3. Cold shock proteins improve E. coli cell‐free synthesis in terms of soluble yields of aggregation‐prone proteins

    Article • Biotechnology and Bioengineering, March 2020, Wiley

    Takanori Kigawa

  4. Amino-acid selective isotope labeling enables simultaneous overlapping signal decomposition and information extraction from NMR spectra

    Article • Journal of Biomolecular NMR, January 2020, Springer Science + Business Media

    Takanori Kigawa

  5. Advances in stable isotope assisted labeling strategies with information science

    Article • Archives of Biochemistry and Biophysics, August 2017, Elsevier

    Takanori Kigawa

  6. Molecular actions of two synthetic brassinosteroids, iso-carbaBL and 6-deoxoBL, which cause altered physiological activities between Arabidopsis and rice

    Article • PLOS One, April 2017, PLOS

    Takanori Kigawa

  7. Impact of cellular health conditions on the protein folding state in mammalian cells

    Article • Chemical Communications, January 2017, Royal Society of Chemistry

    Takanori Kigawa

  8. Angucycline antibiotic waldiomycin recognizes common structural motif conserved in bacterial histidine kinases

    Article • The Journal of Antibiotics, December 2016, Springer Science + Business Media

    Takanori Kigawa

  9. Effect of Glu12-His89 Interaction on Dynamic Structures in HIV-1 p17 Matrix Protein Elucidated by NMR

    Article • PLOS One, December 2016, PLOS

    Takanori Kigawa

  10. Solution structure of the first RNA recognition motif domain of human spliceosomal protein SF3b49 and its mode of interaction with a SF3b145 fragment

    Article • Protein Science, November 2016, Wiley

    Takanori Kigawa

  11. A pre-metazoan origin of the CRK gene family and co-opted signaling network

    Article • Scientific Reports, September 2016, Springer Science + Business Media

    Takanori Kigawa

  12. A novel sphingomyelin/cholesterol domain-specific probe reveals the dynamics of the membrane domains during virus release and in Niemann-Pick type C

    Article • The FASEB Journal, August 2016, Federation of American Societies For Experimental Biology (FASEB)

    Professor Robert G. Parton, Professor Tetsuyuki Kobayashi, Takanori Kigawa

  13. Intracellular Delivery of Proteins via Fusion Peptides in Intact Plants

    Article • PLOS One, April 2016, PLOS

    Takanori Kigawa

  14. Accurate and molecular-size-tolerant NMR quantitation of diverse components in solution

    Article • Scientific Reports, February 2016, Springer Science + Business Media

    Takanori Kigawa

  15. Direct introduction of neomycin phosphotransferase II protein into apple leaves to confer kanamycin resistance

    Article • Plant Biotechnology, January 2016, Japanese Society for Plant Cell and Molecular Biology

    Takanori Kigawa

  16. Stable isotope labeling strategy based on coding theory

    Article • Journal of Biomolecular NMR, August 2015, Springer Science + Business Media

    Takanori Kigawa

  17. Solution structures of the DNA-binding domains of immune-related zinc-finger protein ZFAT

    Article • Journal of Structural and Functional Genomics, March 2015, Springer Science + Business Media

    Takanori Kigawa

  18. Comparison of residual alpha- and beta-structures between two intrinsically disordered proteins by using NMR

    Article • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, March 2015, Elsevier

    Takanori Kigawa

  19. Co-expression of Two Polyhydroxyalkanoate Synthase Subunits from Synechocystis sp. PCC 6803 by Cell-Free Synthesis and Their Specific Activity for Polymerization of 3-Hydroxybutyryl-Coenzyme A

    Article • Biochemistry, February 2015, American Chemical Society (ACS)

    Takanori Kigawa

  20. Molecular level evaluation on HEMA interaction with a collagen model

    Article • Dental Materials, February 2015, Elsevier

    Takanori Kigawa

  21. Long-range effects of tag sequence on marginally stabilized structure in HIV-1 p24 capsid protein monitored using NMR

    Article • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, September 2014, Elsevier

    Takanori Kigawa

  22. Novel RNA recognition motif domain in the cytoplasmic polyadenylation element binding protein 3

    Article • Proteins Structure Function and Bioinformatics, August 2014, Wiley

    Takanori Kigawa

  23. Role of 2-hydroxyethyl methacrylate in the interaction of dental monomers with collagen studied by saturation transfer difference NMR

    Article • Journal of Dentistry, April 2014, Elsevier

    Takanori Kigawa

  24. Flexible and rigid structures in HIV-1 p17 matrix protein monitored by relaxation and amide proton exchange with NMR

    Article • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, March 2014, Elsevier

    Takanori Kigawa

  25. DNA-binding domains of plant-specific transcription factors: structure, function, and evolution

    Article • Trends in Plant Science, May 2013, Elsevier

    Takanori Kigawa

  26. Aberrant Assembly of RNA Recognition Motif 1 Links to Pathogenic Conversion of TAR DNA-binding Protein of 43 kDa (TDP-43)

    Article • Journal of Biological Chemistry, April 2013, American Society for Biochemistry & Molecular Biology (ASBMB)

    Takanori Kigawa

  27. Cell-free synthesis system suitable for disulfide-containing proteins

    Article • Biochemical and Biophysical Research Communications, February 2013, Elsevier

    Takanori Kigawa

  28. Monomer-Collagen Interactions Studied by Saturation Transfer Difference NMR

    Article • Journal of Dental Research, January 2013, SAGE Publications

    Takanori Kigawa

  29. Rapid biochemical synthesis of 11C-labeled single chain variable fragment antibody for immuno-PET by cell-free protein synthesis

    Article • Bioorganic & Medicinal Chemistry, November 2012, Elsevier

    Takanori Kigawa

  30. Active Intermediates of Polyhydroxyalkanoate Synthase from Aeromonas caviae in Polymerization Reaction

    Article • Biomacromolecules, October 2012, American Chemical Society (ACS)

    Takanori Kigawa

  31. Structural insight into the interaction of ADP-ribose with the PARP WWE domains

    Article • FEBS Letters, September 2012, Wiley

    Takanori Kigawa

  32. Simplification of the genetic code: restricted diversity of genetically encoded amino acids

    Article • Nucleic Acids Research, August 2012, Oxford University Press (OUP)

    Takanori Kigawa

  33. Solution structure and siRNA-mediated knockdown analysis of the mitochondrial disease-related protein C12orf65

    Article • Proteins Structure Function and Bioinformatics, August 2012, Wiley

    Takanori Kigawa

  34. An automated system designed for large scale NMR data deposition and annotation: application to over 600 assigned chemical shift data entries to the BioMagResBank from the Riken Structural Genomics/Proteomics Initiative internal database

    Article • Journal of Biomolecular NMR, June 2012, Springer Science + Business Media

    Takanori Kigawa

  35. Solution structures of the double-stranded RNA-binding domains from rna helicase A

    Article • Proteins Structure Function and Bioinformatics, March 2012, Wiley

    Takanori Kigawa

  36. Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms

    Article • Proceedings of the National Academy of Sciences, February 2012, Proceedings of the National Academy of Sciences

    Takanori Kigawa

  37. Structural Basis for Sequence-specific DNA Recognition by anArabidopsisWRKY Transcription Factor

    Article • Journal of Biological Chemistry, January 2012, American Society for Biochemistry & Molecular Biology (ASBMB)

    Takanori Kigawa

  38. A Multiphysics Model of In Vitro Transcription Coupling Enzymatic Reaction and Precipitation Formation

    Article • Biophysical Journal, January 2012, Elsevier

    Takanori Kigawa

  39. Solution structure of the splicing factor motif of the human Prp18 protein

    Article • Proteins Structure Function and Bioinformatics, December 2011, Wiley

    Takanori Kigawa

  40. RING Domain Mutations Uncouple TRIM5  Restriction of HIV-1 from Inhibition of Reverse Transcription and Acceleration of Uncoating

    Article • Journal of Virology, November 2011, ASM Journals

    Takanori Kigawa

  41. Phosphatidylinositol monophosphate-binding interface in the oomycete RXLR effector AVR3a is required for its stability in host cells to modulate plant immunity

    Article • Proceedings of the National Academy of Sciences, August 2011, Proceedings of the National Academy of Sciences

    Dr Sebastian Schornack, Takanori Kigawa

  42. ZF21 Protein, a Regulator of the Disassembly of Focal Adhesions and Cancer Metastasis, Contains a Novel Noncanonical Pleckstrin Homology Domain

    Article • Journal of Biological Chemistry, July 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Takanori Kigawa

  43. Contribution of E3-Ubiquitin Ligase Activity to HIV-1 Restriction by TRIM5 rh: Structure of the RING Domain of TRIM5 

    Article • Journal of Virology, July 2011, ASM Journals

    Takanori Kigawa

  44. NMR Solution Structure of Human Vaccinia-related Kinase 1 (VRK1) Reveals the C-terminal Tail Essential for Its Structural Stability and Autocatalytic Activity

    Article • Journal of Biological Chemistry, May 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Takanori Kigawa

  45. Crystal structure of sulfolobus tokodaii sua5 complexed with L-threonine and AMPPNP

    Article • Proteins Structure Function and Bioinformatics, May 2011, Wiley

    Takanori Kigawa

  46. A practical method for cell-free protein synthesis to avoid stable isotope scrambling and dilution

    Article • Analytical Biochemistry, April 2011, Elsevier

    Takanori Kigawa

  47. Structures of the first and second double-stranded RNA-binding domains of human TAR RNA-binding protein

    Article • Protein Science, December 2010, Wiley

    Takanori Kigawa

  48. An economical method for producing stable-isotope labeled proteins by the E. coli cell-free system

    Article • Journal of Biomolecular NMR, November 2010, Springer Science + Business Media

    Takanori Kigawa

  49. Solution Structure of the Catalytic Domain of the Mitochondrial Protein ICT1 That Is Essential for Cell Vitality

    Article • Journal of Molecular Biology, November 2010, Elsevier

    Takanori Kigawa

  50. Structural basis for the dual RNA-recognition modes of human Tra2-β RRM

    Article • Nucleic Acids Research, October 2010, Oxford University Press (OUP)

    Takanori Kigawa, Dr. Akiko Tanaka

  51. NMR and X-ray structures of the putative sterol carrier protein 2 from Thermus thermophilus HB8 show conformational changes

    Article • Journal of Structural and Functional Genomics, October 2010, Springer Science + Business Media

    Takanori Kigawa

  52. Structural Insight into the Zinc Finger CW Domain as a Histone Modification Reader

    Article • Structure, September 2010, Elsevier

    Takanori Kigawa

  53. Solution Structure of Histone Chaperone ANP32B: Interaction with Core Histones H3–H4 through Its Acidic Concave Domain

    Article • Journal of Molecular Biology, August 2010, Elsevier

    Takanori Kigawa

  54. Site-specific incorporation of 4-Iodo-l-phenylalanine through opal suppression

    Article • The Journal of Biochemistry, May 2010, Oxford University Press (OUP)

    Takanori Kigawa

  55. Structural basis for the recognition of nucleophosmin-anaplastic lymphoma kinase oncoprotein by the phosphotyrosine binding domain of Suc1-associated neurotrophic factor-induced tyrosine-phosphorylated target-2

    Article • Journal of Structural and Functional Genomics, May 2010, Springer Science + Business Media

    Takanori Kigawa, Dr. Akiko Tanaka

  56. The NMR solution structures of the five constituent cold-shock domains (CSD) of the human UNR (upstream of N-ras) protein

    Article • Journal of Structural and Functional Genomics, March 2010, Springer Science + Business Media

    Takanori Kigawa, Dr. Akiko Tanaka

  57. The C-Terminal BAG Domain of BAG5 Induces Conformational Changes of the Hsp70 Nucleotide- Binding Domain for ADP-ATP Exchange

    Article • Structure, March 2010, Elsevier

    Takanori Kigawa

  58. Solution structure of the C-terminal DUF1000 domain of the human thioredoxin-like 1 protein

    Article • Proteins Structure Function and Bioinformatics, January 2010, Wiley

    Takanori Kigawa, Dr. Akiko Tanaka

  59. Automated system for high-throughput protein production using the dialysis cell-free method

    Article • Protein Expression and Purification, December 2009, Elsevier

    Takanori Kigawa

  60. Analysis of Protein Functions Through a Bacterial Cell-Free Protein Expression System

    Article • November 2009, Springer Science + Business Media

    Takanori Kigawa

  61. Cell-Free Protein Preparation Through Prokaryotic Transcription–Translation Methods

    Article • November 2009, Springer Science + Business Media

    Takanori Kigawa

  62. Cell-Free Protein Production System with the E. coli Crude Extract for Determination of Protein Folds

    Article • November 2009, Springer Science + Business Media

    Takanori Kigawa

  63. NMR solution structures of actin depolymerizing factor homology domains

    Article • Protein Science, November 2009, Wiley

    Takanori Kigawa, Dr. Akiko Tanaka

  64. Structural and Functional Characterization of the NHR1 Domain of the Drosophila Neuralized E3 Ligase in the Notch Signaling Pathway

    Article • Journal of Molecular Biology, October 2009, Elsevier

    Takanori Kigawa, Dr. Akiko Tanaka

  65. A B-Box 2 Surface Patch Important for TRIM5α Self-Association, Capsid Binding Avidity, and Retrovirus Restriction

    Article • Journal of Virology, August 2009, ASM Journals

    Dr Andres Finzi, Takanori Kigawa

  66. Multiple inhibitory factor removal from an Escherichia coli cell extract improves cell-free protein synthesis

    Article • Journal of Bioscience and Bioengineering, July 2009, Elsevier

    Takanori Kigawa

  67. Structural basis for the sequence-specific RNA-recognition mechanism of human CUG-BP1 RRM3

    Article • Nucleic Acids Research, June 2009, Oxford University Press (OUP)

    Takanori Kigawa, Dr. Akiko Tanaka

  68. Novel dimerization mode of the human Bcl-2 family protein Bak, a mitochondrial apoptosis regulator

    Article • Journal of Structural Biology, April 2009, Elsevier

    Takanori Kigawa, Dr. Akiko Tanaka

  69. Solution structure of the cysteine-rich domain in Fn14, a member of the tumor necrosis factor receptor superfamily

    Article • Protein Science, January 2009, Wiley

    Takanori Kigawa, Dr. Akiko Tanaka

  70. Solution structure of the GUCT domain from human RNA helicase II/Guβ reveals the RRM fold, but implausible RNA interactions

    Article • Proteins Structure Function and Bioinformatics, January 2009, Wiley

    Takanori Kigawa, Dr. Akiko Tanaka

  71. A new modeling method in feature construction for the HSQC spectra screening problem

    Article • Bioinformatics, July 2008, Oxford University Press (OUP)

    Takanori Kigawa

  72. Solution structure of the RNA binding domain in the human muscleblind-like protein 2

    Article • Protein Science, January 2008, Wiley

    Takanori Kigawa, Dr. Akiko Tanaka

  73. Site-Specific Functionalization of Proteins by Organopalladium Reactions

    Article • ChemBioChem, January 2007, Wiley

    Takanori Kigawa

  74. Improving cell-free protein synthesis for stable-isotope labeling

    Article • Journal of Biomolecular NMR, January 2007, Springer Science + Business Media

    Takanori Kigawa

  75. Effects ofEscherichia coliribosomal protein S12 mutations on cell-free protein synthesis

    Article • FEBS Journal, February 2004, Wiley

    Takanori Kigawa

  76. Article • Journal of Biomolecular NMR, January 2002, Springer Science + Business Media

    Takanori Kigawa

  77. Article • Journal of Structural and Functional Genomics, January 2002, Springer Science + Business Media

    Takanori Kigawa

  78. Article • Nature Structural Biology, November 2000, Springer Science + Business Media

    Takanori Kigawa

  79. Article • Seibutsu Butsuri, January 2000, Biophysical Society of Japan

    Takanori Kigawa

  80. Article • Journal of Biomolecular NMR, January 1998, Springer Science + Business Media

    Takanori Kigawa

  81. A Highly Efficient Cell-Free Protein Synthesis System from Escherichia coli

    Article • FEBS Journal, August 1996, Wiley

    Takanori Kigawa

  82. Cell-free synthesis and amino acid-selective stable isotope labeling of proteins for NMR analysis

    Article • Journal of Biomolecular NMR, September 1995, Springer Science + Business Media

    Takanori Kigawa

  83. Incorporation of unnatural amino acids proteins.

    Article • Kobunshi, January 1990, Society of Polymer Science, Japan

    Takanori Kigawa