All Stories

  1. Multidisciplinary genomic evaluation reveals adult inborn errors of immunity with rheumatic features

    Article • Journal of Human Immunity, August 2026, Rockefeller University Press

    Assitant Professor Tadashi Hosoya

  2. Clinical and healthcare burden of difficult-to-treat rheumatoid arthritis in Japan: a retrospective cohort study

    Article • BMJ Open, August 2026, BMJ

    Assitant Professor Tadashi Hosoya

  3. Polyarteritis Nodosa Presenting with a String-of-Beads Appearance Mimicking Fibromuscular Dysplasia on Arteriography

    Article • QJM, July 2026, Oxford University Press (OUP)

    Assitant Professor Tadashi Hosoya

  4. Atypical adult chronic non-bacterial osteomyelitis (CNO) in skull

    Article • EJNMMI Reports, February 2026, Springer Science + Business Media

    Assitant Professor Tadashi Hosoya

  5. Long COVID is associated with female sex; Anti-NCAM1 autoantibodies are absent in patients with long COVID

    Article • IBRO Neuroscience Reports, December 2025, Elsevier

    Assitant Professor Tadashi Hosoya

  6. Long COVID: mechanisms of disease, multisystem sequelae, and prospects for treatment

    Article • Immunological Medicine, October 2025, Taylor & Francis

    Assitant Professor Tadashi Hosoya

  7. Successfully treated mandibular osteomyelitis by TNF inhibitor in SAPHO syndrome

    Article • Arthritis & Rheumatology, September 2025, Wiley

    Assitant Professor Tadashi Hosoya

  8. Iguratimod, a promising therapeutic agent for COVID-19 that attenuates excessive inflammation in mouse models

    Article • European Journal of Pharmacology, June 2025, Elsevier

    Assitant Professor Tadashi Hosoya

  9. The role of TRECs/KRECs as immune indicators that reflect immunophenotypes and predict the risk of infection in systemic autoimmune diseases

    Article • Immunological Medicine, February 2025, Taylor & Francis

    Assitant Professor Tadashi Hosoya

  10. Long-term outcome of a treat-to-target strategy in late-onset rheumatoid arthritis with chronic lung disease: 5-year results of a prospective observational study

    Article • Arthritis Research & Therapy, February 2025, Springer Science + Business Media

    Assitant Professor Tadashi Hosoya

  11. Prolonged high Myl9 levels are associated with the pathogenesis and respiratory symptom of post-acute COVID-19 syndrome: A 6-month follow-up study

    Article • Clinics, January 2025, Elsevier

    Assitant Professor Tadashi Hosoya

  12. Necroptosis in alveolar epithelial cells drives lung inflammation and injury caused by SARS-CoV-2 infection

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, December 2024, Elsevier

    Assitant Professor Tadashi Hosoya

  13. Involvement of Mediterranean fever gene mutations in colchicine-responsive enterocolitis: a retrospective cohort study

    Article • EBioMedicine, December 2024, Elsevier

    Assitant Professor Tadashi Hosoya, Taku Kobayashi

  14. Cyclin Dependent Kinase Inhibitor: A Long-Awaited, Late-Coming, Novel Class Agent in Rheumatoid Arthritis

    Article • Rheumatology, November 2024, Oxford University Press (OUP)

    Assitant Professor Tadashi Hosoya

  15. Diverse pro-inflammatory ability of mutated spike protein derived from variant strains of SARS-CoV-2

    Article • Cytokine, June 2024, Elsevier

    Assitant Professor Tadashi Hosoya

  16. Effectiveness and safety of treat-to-target strategy for methotrexate-naïve rheumatoid arthritis patients over 75 years of age

    Article • Rheumatology Advances in Practice, February 2024, Oxford University Press (OUP)

    Assitant Professor Tadashi Hosoya

  17. Anti-inflammatory effects of a novel NF-kB inhibitory derivative derived from pyrazolo[3,4-d]pyrimidine in three inflammation models

    Article • Journal of Pharmacology and Experimental Therapeutics, January 2024, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Assitant Professor Tadashi Hosoya

  18. Thrombosis and antiphospholipid antibodies in Japanese COVID-19: based on propensity score matching

    Article • Frontiers in Immunology, October 2023, Frontiers

    Assitant Professor Tadashi Hosoya

  19. Expression of the readthrough transcript CiDRE in alveolar macrophages boosts SARS-CoV-2 susceptibility and promotes COVID-19 severity

    Article • Immunity, August 2023, Elsevier

    Assitant Professor Tadashi Hosoya

  20. Abdominal obesity increases the risk of death in COVID-19

    Article • Proceedings of the National Academy of Sciences, May 2023, Proceedings of the National Academy of Sciences

    Assitant Professor Tadashi Hosoya

  21. Leucine-rich alpha-2 glycoprotein as a potential biomarker for large vessel vasculitides

    Article • Frontiers in Medicine, May 2023, Frontiers

    Assitant Professor Tadashi Hosoya

  22. A novel gain-of-function missense variant in PLCG2 associated with autoinflammation and hypergammaglobulinaemia

    Article • Rheumatology, April 2023, Oxford University Press (OUP)

    Assitant Professor Tadashi Hosoya

  23. Mass-like Lesions Causing Compression of Large Vessels in Granulomatosis with Polyangiitis: A Case Report

    Article • Internal Medicine, January 2023, Japanese Society of Internal Medicine

    Assitant Professor Tadashi Hosoya

  24. Hemorrhagic gastric ulcer in a patient with Behcet's disease successfully treated with infliximab

    Article • DEN Open, December 2022, Wiley

    Assitant Professor Tadashi Hosoya

  25. Factors associated with impaired physical function in elderly rheumatoid arthritis patients who had achieved low disease activity

    Article • Modern Rheumatology, December 2022, Oxford University Press (OUP)

    Assitant Professor Tadashi Hosoya

  26. Correction: CD34+THY1+ synovial fibroblast subset in arthritic joints has high osteoblastic and chondrogenic potentials in vitro

    Article • September 2022, Springer Science + Business Media

    Assitant Professor Tadashi Hosoya

  27. An adult case of suspected A20 haploinsufficiency mimicking polyarteritis nodosa

    Article • Rheumatology, May 2022, Oxford University Press (OUP)

    Assitant Professor Tadashi Hosoya

  28. Associated factors with poor treatment response to initial glucocorticoid therapy in patients with adult-onset Still’s disease

    Article • April 2022, Springer Science + Business Media

    Assitant Professor Tadashi Hosoya

  29. Therapeutic Effect of Cyclin‐Dependent Kinase 4/6 Inhibitor on Dermal Fibrosis in Murine Models of Systemic Sclerosis

    Article • Arthritis & Rheumatology, March 2022, Wiley

    Assitant Professor Tadashi Hosoya

  30. CD34+THY1+ synovial fibroblast subset in arthritic joints has high osteoblastic and chondrogenic potentials in vitro

    Article • February 2022, Springer Science + Business Media

    Assitant Professor Tadashi Hosoya

  31. Small Molecule Calcium Channel Activator Potentiates Adjuvant Activity

    Article • ACS Chemical Biology, January 2022, American Chemical Society (ACS)

    Assitant Professor Tadashi Hosoya

  32. Plasma Levels of Decorin Increased in Patients during the Progression of Breast Cancer

    Article • Journal of Clinical Medicine, November 2021, MDPI AG

    Assitant Professor Tadashi Hosoya

  33. Chondroprotective effects of CDK4/6 inhibition via enhanced ubiquitin-dependent degradation of JUN in synovial fibroblasts

    Article • Rheumatology, November 2021, Oxford University Press (OUP)

    Assitant Professor Tadashi Hosoya

  34. Arterial and Venous Thrombosis Complicated in COVID-19: A Retrospective Single Center Analysis in Japan

    Article • Frontiers in Cardiovascular Medicine, November 2021, Frontiers

    Assitant Professor Tadashi Hosoya

  35. Small Molecule Potentiator of Adjuvant Activity Enhancing Survival to Influenza Viral Challenge

    Article • Frontiers in Immunology, September 2021, Frontiers

    Assitant Professor Tadashi Hosoya

  36. Editorial: Targeting the Chemoattractant System in Inflammation

    Article • Frontiers in Pharmacology, August 2021, Frontiers

    Assitant Professor Tadashi Hosoya

  37. Effectiveness and safety of treat-to-target strategy in elderly-onset rheumatoid arthritis: a 3-year prospective observational study

    Article • Rheumatology, January 2021, Oxford University Press (OUP)

    Assitant Professor Tadashi Hosoya

  38. Identification of Compounds With Glucocorticoid Sparing Effects on Suppression of Chemokine and Cytokine Production by Rheumatoid Arthritis Fibroblast-Like Synoviocytes

    Article • Frontiers in Pharmacology, December 2020, Frontiers

    Assitant Professor Tadashi Hosoya

  39. Discovery of a Novel Microtubule Targeting Agent as an Adjuvant for Cancer Immunotherapy

    Article • BioMed Research International, October 2018, Hindawi Publishing Corporation

    Assitant Professor Tadashi Hosoya

  40. Induction of oligoclonal CD8 T cell responses against pulmonary metastatic cancer by a phospholipid-conjugated TLR7 agonist

    Article • Proceedings of the National Academy of Sciences, July 2018, Proceedings of the National Academy of Sciences

    Assitant Professor Tadashi Hosoya

  41. Identification of Compounds That Prolong Type I Interferon Signaling as Potential Vaccine Adjuvants

    Article • SLAS DISCOVERY, May 2018, SAGE Publications

    Assitant Professor Tadashi Hosoya

  42. Evaluation of the alternative classification criteria of systemic lupus erythematosus established by Systemic Lupus International Collaborating Clinics (SLICC)

    Article • Modern Rheumatology, November 2017, Taylor & Francis

    Assitant Professor Tadashi Hosoya

  43. Combination immunotherapy with TLR agonists and checkpoint inhibitors suppresses head and neck cancer

    Article • JCI Insight, September 2017, American Society for Clinical Investigation

    Assitant Professor Tadashi Hosoya

  44. Successful use of rituximab in a patient with refractory thrombotic thrombocytopaenic purpura complicated by polymyositis

    Article • Scandinavian Journal of Rheumatology, June 2016, Taylor & Francis

    Assitant Professor Tadashi Hosoya

  45. Acquired Gitelman Syndrome in an Anti-SSA Antibody-positive Patient with a <i>SLC12A3</i> Heterozygous Mutation

    Article • Internal Medicine, January 2016, Japanese Society of Internal Medicine

    Assitant Professor Tadashi Hosoya

  46. A Case Presenting with the Clinical Characteristics of Tumor Necrosis Factor (TNF) Receptor-associated Periodic Syndrome (TRAPS) without <i>TNFRSF1A</i> Mutations Successfully Treated with Tocilizumab

    Article • Internal Medicine, January 2015, Japanese Society of Internal Medicine

    Assitant Professor Tadashi Hosoya

  47. Structural and functional outcomes of a therapeutic strategy targeting low disease activity in patients with elderly-onset rheumatoid arthritis: a prospective cohort study (CRANE)

    Article • Rheumatology, October 2014, Oxford University Press (OUP)

    Assitant Professor Tadashi Hosoya

  48. Cell cycle regulation therapy combined with cytokine blockade enhances antiarthritic effects without increasing immune suppression

    Article • Annals of the Rheumatic Diseases, August 2014, BMJ

    Assitant Professor Tadashi Hosoya

  49. Suppression of elevations in serum C reactive protein levels by anti-IL-6 autoantibodies in two patients with severe bacterial infections

    Article • Annals of the Rheumatic Diseases, January 2013, BMJ

    Assitant Professor Tadashi Hosoya

  50. Etanercept-induced necrotizing crescentic glomerulonephritis in two patients with rheumatoid arthritis

    Article • Modern Rheumatology, December 2010, Oxford University Press (OUP)

    Assitant Professor Tadashi Hosoya