All Stories

  1. Transcriptional Repression of CCL2 by KCa3.1 K+ Channel Activation and LRRC8A Anion Channel Inhibition in THP-1-Differentiated M2 Macrophages

    Article • International Journal of Molecular Sciences, August 2025, MDPI AG

    Dr. Susumu Ohya

  2. Downregulation of IL-8 and IL-10 by LRRC8A Inhibition through the NOX2–Nrf2–CEBPB Transcriptional Axis in THP-1-Derived M2 Macrophages

    Article • International Journal of Molecular Sciences, September 2024, MDPI AG

    Dr. Susumu Ohya

  3. Transcriptional Up-Regulation of FBXW7 by KCa1.1 K+ Channel Inhibition through the Nrf2 Signaling Pathway in Human Prostate Cancer LNCaP Cell Spheroid Model

    Article • International Journal of Molecular Sciences, May 2024, MDPI AG

    Dr. Susumu Ohya

  4. Down-Regulation of CYP3A4 by the KCa1.1 Inhibition Is Responsible for Overcoming Resistance to Doxorubicin in Cancer Spheroid Models

    Article • International Journal of Molecular Sciences, October 2023, MDPI AG

    Dr. Susumu Ohya

  5. Recent Developments in Ion Channel and Ion-Related Signaling

    Article • International Journal of Molecular Sciences, September 2023, MDPI AG

    Dr. Susumu Ohya

  6. Downregulation of IL-8 and IL-10 by the Activation of Ca2+-Activated K+ Channel KCa3.1 in THP-1-Derived M2 Macrophages

    Article • International Journal of Molecular Sciences, August 2022, MDPI AG

    Dr. Susumu Ohya

  7. KCa1.1 K+ Channel Inhibition Overcomes Resistance to Antiandrogens and Doxorubicin in a Human Prostate Cancer LNCaP Spheroid Model

    Article • International Journal of Molecular Sciences, December 2021, MDPI AG

    Dr. Susumu Ohya

  8. Role of K+ and Ca2+-Permeable Channels in Osteoblast Functions

    Article • International Journal of Molecular Sciences, September 2021, MDPI AG

    Dr. Susumu Ohya

  9. Inhibition of Interleukin 10 Transcription through the SMAD2/3 Signaling Pathway by Ca2+-Activated K+Channel KCa3.1 Activation in Human T-Cell Lymphoma HuT-78 Cells

    Article • Molecular Pharmacology, January 2019, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr. Susumu Ohya

  10. Histone Deacetylases Enhance Ca2+-Activated K+ Channel KCa3.1 Expression in Murine Inflammatory CD4+ T Cells

    Article • International Journal of Molecular Sciences, September 2018, MDPI AG

    Dr. Susumu Ohya

  11. ATP increases [Ca2+ ]i and activates a Ca2+ -dependent Cl− current in rat ventricular fibroblasts

    Article • Quarterly Journal of Experimental Physiology and Cognate Medical Sciences, April 2018, Wiley

    Dr. Susumu Ohya

  12. Regulation of KCa3.1 by HDAC inhibition

    Article • Pharmacology Research & Perspectives, March 2016, Wiley

    Dr. Susumu Ohya