All Stories

  1. DModE: An end-to-end framework for Differential Modification and Expression Analysis of Nanopore direct RNA sequencing data
  2. Sex-specific regulation of angiogenin in Alzheimer’s disease
  3. Benchmarking ambient RNA removal across droplet and well-plate platforms reveals artificial count generation as a critical failure mode of scAR and CellClear
  4. Mapping human pre-rRNA processing and modification at single nucleotide resolution using long read nanopore sequencing
  5. Real-time transcriptomic profiling in distinct experimental conditions
  6. Deep Learning Reaction Framework (DLRN) for kinetic modeling of time-resolved data
  7. Direct RNA sequencing enables improved transcriptome assessment and tracking of RNA modifications for medical applications
  8. ModiDeC: a multi-RNA modification classifier for direct nanopore sequencing
  9. Mapping human pre-rRNA processing and modification at single nucleotide resolution using long read Nanopore sequencing
  10. Enhancing Detection of Polygenic Adaptation: A Comparative Study of Machine Learning and Statistical Approaches Using Simulated Evolve-and-Resequence Data
  11. Pod5Viewer: a GUI for inspecting raw nanopore sequencing data
  12. Selective RNA pseudouridinylation in situ by circular gRNAs in designer organelles
  13. Stage-specific expression patterns and co-targeting relationships among miRNAs in the developing mouse cerebral cortex
  14. Deep Learning Reaction Network (DLRN): a deep learning kinetic model analysis for time-resolved data
  15. Deep Learning Reaction Network: a machine learning framework for modeling time resolved data
  16. Real-time transcriptomic profiling in distinct experimental conditions
  17. Neuroimage Denoiser for removing noise from transient fluorescent signals in functional imaging
  18. Chromatin Capture Upsampling Toolbox - CCUT: A Versatile and unified Framework to Train Your Chromatin Capture Deep Learning Models
  19. Long non-coding RNAs expression and regulation across different brain regions in primates
  20. Characterization of transcriptional profiles associated with stress-induced neuronal activation in Arc-GFP mice
  21. Cortexa – a comprehensive resource for studying gene expression and alternative splicing in the murine brain
  22. Real-time transcriptomic profiling in distinct experimental conditions
  23. Stage-specific expression patterns and co-targeting relationships among miRNAs in the developing mouse cerebral cortex
  24. Freezing responses during prolonged threat memory retrieval reflect trait-like anxiety endophenotypes in female and male inbred mice
  25. A mathematical model of the Alzheimer’s Disease biomarker cascade demonstrates statistical pitfalls in identifying neurobiological surrogates of cognitive reserve
  26. Characterization of transcriptional profiles associated with stress-induced neuronal activation in Arc-GFP mice
  27. NanopoReaTA: a user-friendly tool for nanopore-seq real-time transcriptional analysis
  28. NAPE-PLD deletion in stress-TRAPed neurons results in an anxiogenic phenotype
  29. Nuclei on the Rise: When Nuclei-Based Methods Meet Next-Generation Sequencing
  30. On cheap entropy-sparsified regression learning
  31. NanopoReaTA: a user-friendly tool for nanopore-seq real-time transcriptional analysis
  32. A Resilience Related Glial-Neurovascular Network Is Transcriptionally Activated after Chronic Social Defeat in Male Mice
  33. CollembolAI, a macrophotography and computer vision workflow to digitize and characterize samples of soil invertebrate communities preserved in fluid
  34. Low-Cost Probabilistic 3D Denoising with Applications for Ultra-Low-Radiation Computed Tomography
  35. Selective targeting of chronic social stress-induced activated neurons identifies neurogenesis-related genes to be associated with resilience in female mice
  36. Long‐term molecular differences between resilient and susceptible mice after a single traumatic exposure
  37. Co-Inference of Data Mislabelings Reveals Improved Models in Genomics and Breast Cancer Diagnostics
  38. beeRapp: an R shiny app for automated high-throughput explorative analysis of multivariate behavioral data
  39. Photoperiod is an important seasonal selection factor in Chironomus riparius (Diptera: Chironomidae)
  40. IntelliPy: a GUI for analyzing IntelliCage data
  41. The gut microbiota instructs the hepatic endothelial cell transcriptome
  42. N6 -Methyladenosine Modification in Chronic Stress Response Due to Social Hierarchy Positioning of Mice
  43. Quality-preserving low-cost probabilistic 3D denoising with applications to Computed Tomography
  44. Genomic basis for drought resistance in European beech forests threatened by climate change
  45. mTOR Driven Gene Transcription Is Required for Cholesterol Production in Neurons of the Developing Cerebral Cortex
  46. INTACT vs. FANS for Cell-Type-Specific Nuclei Sorting: A Comprehensive Qualitative and Quantitative Comparison
  47. Transcriptional signatures in prefrontal cortex confer vulnerability versus resilience to food and cocaine addiction-like behavior
  48. Dichotomic Hippocampal Transcriptome After Glutamatergic vs. GABAergic Deletion of the Cannabinoid CB1 Receptor
  49. Voluntary Wheel Running Did Not Alter Gene Expression in 5xfad Mice, but in Wild-Type Animals Exclusively after One-Day of Physical Activity
  50. tbg - a new file format for genomic data
  51. A deeper look into natural sciences with physics-based and data-driven measures
  52. Reliability of genomic variants across different next-generation sequencing platforms and bioinformatic processing pipelines
  53. Common Factors in Neurodegeneration: A Meta-Study Revealing Shared Patterns on a Multi-Omics Scale
  54. Genomic basis of drought resistance inFagus sylvatica
  55. Isolation of nuclei and downstream processing of cell-type-specific nuclei from micro-dissected mouse brain regions – techniques and caveats
  56. mTOR driven gene transcription is required for cholesterol production in neurons of the developing cerebral cortex
  57. Reliability of genomic variants across different next-generation sequencing platforms and bioinformatic processing pipelines
  58. Dynamic longitudinal behavior in animals exposed to chronic social defeat stress
  59. Germ-free housing conditions do not affect aortic root and aortic arch lesion size of late atherosclerotic low-density lipoprotein receptor-deficient mice
  60. Prevention of age-associated neuronal hyperexcitability with improved learning and attention upon knockout or antagonism of LPAR2
  61. Impact of Acute and Chronic Amyloid-β Peptide Exposure on Gut Microbial Commensals in the Mouse
  62. Applying univariate vs. multivariate statistics to investigate therapeutic efficacy in (pre)clinical trials: A Monte Carlo simulation study on the example of a controlled preclinical neurotrauma trial
  63. α-Linolenic Acid-Rich Diet Influences Microbiota Composition and Villus Morphology of the Mouse Small Intestine
  64. A specific prelimbic-nucleus accumbens pathway controls resilience versus vulnerability to food addiction
  65. Low-cost scalable discretization, prediction, and feature selection for complex systems
  66. Dynamic longitudinal behavior in animals exposed to chronic social defeat stress
  67. The Microbiota Promotes Arterial Thrombosis in Low-Density Lipoprotein Receptor-Deficient Mice
  68. Low-cost scalable discretization, prediction and feature selection for complex systems
  69. Common miRNA Patterns of Alzheimer’s Disease and Parkinson’s Disease and Their Putative Impact on Commensal Gut Microbiota
  70. Imputation of posterior linkage probability relations reveals a significant influence of structural 3D constraints on linkage disequilibrium
  71. A scalable approach to the computation of invariant measures for high-dimensional Markovian systems
  72. Toward a direct and scalable identification of reduced models for categorical processes
  73. A Thermodynamic Model of Monovalent Cation Homeostasis in the Yeast Saccharomyces cerevisiae
  74. Improving clustering by imposing network information
  75. On inference of causality for discrete state models in a multiscale context
  76. Impact of Acute Metal Stress in Saccharomyces cerevisiae
  77. STSE: Spatio-Temporal Simulation Environment Dedicated to Biology
  78. GRAPHICAL ANALYSIS AND EXPERIMENTAL EVALUATION OF SACCHAROMYCES CEREVISIAE P TRK 1|2 AND P BMH 1|2 PROMOTER REGION
  79. Drug-efficacy depends on the inhibitor type and the target position in a metabolic network—A systematic study
  80. On Inference and Validation of Causality Relations in Climate Teleconnections