All Stories

  1. TrkB Regulates N-Methyl-D-Aspartate Receptor Signaling by Uncoupling and Recruiting the Brain-Specific Guanine Nucleotide Exchange Factor, RasGrf1

    Article • Journal of Molecular Neuroscience, December 2018, Springer Science + Business Media

    Dr. Susan O Meakin

  2. Death of Brain Tumors

    Article • Molecular and Cellular Biology, August 2016, ASM Journals

    Dr. Susan O Meakin

  3. Arf6 controls beta-amyloid production by regulating macropinocytosis of the Amyloid Precursor Protein to lysosomes

    Article • Molecular Brain, July 2015, Springer Science + Business Media

    Dr. Susan O Meakin

  4. The Signaling Adapter, FRS2, Facilitates Neuronal Branching in Primary Cortical Neurons via Both Grb2- and Shp2-Dependent Mechanisms

    Article • Journal of Molecular Neuroscience, August 2014, Springer Science + Business Media

    Dr. Susan O Meakin

  5. Quantitative Tissue Ph Measurement during Cerebral Ischemia Using Amine and Amide Concentration-Independent Detection (AACID) with MRI

    Article • Journal of Cerebral Blood Flow & Metabolism, February 2014, SAGE Publications

    Professor Marco A M Prado, Dr. Susan O Meakin

  6. Nerve Growth Factor Receptor TrkA, a New Receptor in Insulin Signaling Pathway in PC12 Cells

    Article • Journal of Biological Chemistry, August 2013, Elsevier

    Dr. Susan O Meakin

  7. Nesca, a novel neuronal adapter protein, links the molecular motor kinesin with the pre‐synaptic membrane protein, syntaxin‐1, in hippocampal neurons

    Article • Journal of Neurochemistry, April 2012, Wiley

    Dr. Susan O Meakin

  8. Trk receptor binding and neurotrophin/fibroblast growth factor (FGF)-dependent activation of the FGF receptor substrate (FRS)-3

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, April 2006, Elsevier

    Dr. Susan O Meakin

  9. Nerve growth factor increases connexin43 phosphorylation and gap junctional intercellular communication

    Article • Journal of Neuroscience Research, November 2005, Wiley

    Dr. Susan O Meakin

  10. Trypanosome trans-sialidase targets TrkA tyrosine kinase receptor and induces receptor internalization and activation

    Article • Glycobiology, June 2004, Oxford University Press (OUP)

    Dr. Susan O Meakin

  11. Nesca, a novel adapter, translocates to the nuclear envelope and regulates neurotrophin-induced neurite outgrowth

    Article • The Journal of Cell Biology, March 2004, Rockefeller University Press

    Dr. Susan O Meakin

  12. Acidic substitution of the activation loop tyrosines in TrkA supports nerve growth factor-dependent, but not nerve growth factor-independent, differentiation and cell cycle arrest in the human neuroblastoma cell line, SY5Y

    Article • Oncogene, November 2003, Springer Science + Business Media

    Dr. Susan O Meakin

  13. Ectopic expression of the TrkA receptor in adult dopaminergic mesencephalic neurons promotes retrograde axonal NGF transport and NGF-dependent neuroprotection

    Article • Experimental Neurology, October 2003, Elsevier

    Dr. Susan O Meakin

  14. The Signaling Adapters Fibroblast Growth Factor Receptor Substrate 2 and 3 Are Activated by the Thyroid TRK Oncoproteins

    Article • Endocrinology, March 2003, Endocrine Society

    Dr. Susan O Meakin

  15. Article • Molecular Biology Reports, January 2003, Springer Science + Business Media

    Dr. Susan O Meakin

  16. Overexpression of the signaling adapter FRS2 reconstitutes the cell cycle deficit of a nerve growth factor non‐responsive TrkA receptor mutant

    Article • Journal of Neurochemistry, May 2002, Wiley

    Dr. Susan O Meakin

  17. PC12nnr5 cells expressing TrkA receptors undergo morphological but not cholinergic phenotypic differentiation in response to nerve growth factor

    Article • Journal of Neurochemistry, January 2002, Wiley

    Dr. Susan O Meakin

  18. Chapter 7 Central mechanisms for autonomic dysreflexia after spinal cord injury

    Article • January 2002, Elsevier

    Dr. Susan O Meakin

  19. p75 Co-receptors Regulate Ligand-dependent and Ligand-independent Trk Receptor Activation, in Part by Altering Trk Docking Subdomains

    Article • Journal of Biological Chemistry, August 2001, Elsevier

    Dr. Susan O Meakin

  20. Developmental expression patterns of the signaling adapters FRS-2 and FRS-3 during early embryogenesis

    Article • Mechanisms of Development, May 2001, Elsevier

    Dr. Susan O Meakin

  21. A Differential Role of Extracellular Signal-Regulated Kinase in Stimulated PC12 Pheochromocytoma Cell Movement

    Article • Experimental Cell Research, February 2001, Elsevier

    Dr. Susan O Meakin

  22. Direct Binding of the Signaling Adapter Protein Grb2 to the Activation Loop Tyrosines on the Nerve Growth Factor Receptor Tyrosine Kinase, TrkA

    Article • Journal of Biological Chemistry, June 2000, Elsevier

    Dr. Susan O Meakin

  23. Acidic substitution of the activation loop tyrosines in TrkA supports nerve growth factor-independent cell survival and neuronal differentiation

    Article • Oncogene, January 2000, Springer Science + Business Media

    Dr. Susan O Meakin

  24. Distinct human NUMB isoforms regulate differentiation vs. proliferation in the neuronal lineage

    Article • Proceedings of the National Academy of Sciences, August 1999, Proceedings of the National Academy of Sciences

    Dr. Susan O Meakin

  25. The Signaling Adapter FRS-2 Competes with Shc for Binding to the Nerve Growth Factor Receptor TrkA

    Article • Journal of Biological Chemistry, April 1999, Elsevier

    Dr. Susan O Meakin

  26. The nerve growth factor family of receptors

    Article • Trends in Neurosciences, September 1992, Elsevier

    Dr. Susan O Meakin

  27. The rat trk protooncogene product exhibits properties characteristic of the slow nerve growth factor receptor.

    Article • Proceedings of the National Academy of Sciences, March 1992, Proceedings of the National Academy of Sciences

    Dr. Susan O Meakin

  28. Chapter 14: Isolation of transcriptionally regulated sequences associated with neuronal and non-neuronal cell interactions

    Article • January 1992, Elsevier

    Dr. Susan O Meakin

  29. γ-Crystallins of the Human Eye Lens: Expression Analysis of Five Members of the Gene Family

    Article • Molecular and Cellular Biology, August 1987, Taylor & Francis

    Dr. Susan O Meakin

  30. Aging effects of vitamin C on a human lens protein produced in vitro

    Article • The FASEB Journal, July 1987, Wiley

    Dr. Susan O Meakin