All Stories

  1. Arylvinylpiperazine Amides, a New Class of Potent Inhibitors Targeting QcrB of Mycobacterium tuberculosis

    Article • mBio, October 2018, ASM Journals

    Stewart Cole

  2. Highly Reduced Genome of the New Species Mycobacterium uberis, the Causative Agent of Nodular Thelitis and Tuberculoid Scrotitis in Livestock and a Close Relative of the Leprosy Bacilli

    Article • mSphere, October 2018, ASM Journals

    Stewart Cole

  3. Optimized Background Regimen for Treatment of Active Tuberculosis with the Next-Generation Benzothiazinone Macozinone (PBTZ169)

    Article • Antimicrobial Agents and Chemotherapy, August 2018, ASM Journals

    Stewart Cole

  4. Structure-Based Drug Design and Characterization of Sulfonyl-Piperazine Benzothiazinone Inhibitors of DprE1 from Mycobacterium tuberculosis

    Article • Antimicrobial Agents and Chemotherapy, July 2018, ASM Journals

    Stewart Cole

  5. Insights from the Genome Sequence of Mycobacterium lepraemurium: Massive Gene Decay and Reductive Evolution

    Article • mBio, October 2017, ASM Journals

    Stewart Cole

  6. Rv3852 (H-NS) of Mycobacterium tuberculosis Is Not Involved in Nucleoid Compaction and Virulence Regulation

    Article • Journal of Bacteriology, May 2017, ASM Journals

    Stewart Cole

  7. EspC forms a filamentous structure in the cell envelope ofMycobacterium tuberculosisand impacts ESX-1 secretion

    Article • Molecular Microbiology, November 2016, Wiley

    Stewart Cole

  8. InhibitingMycobacterium tuberculosiswithin and without

    Article • Philosophical Transactions of the Royal Society B Biological Sciences, September 2016, Royal Society Publishing

    Stewart Cole

  9. Characterization of DprE1-Mediated Benzothiazinone Resistance in Mycobacterium tuberculosis

    Article • Antimicrobial Agents and Chemotherapy, August 2016, ASM Journals

    Stewart Cole

  10. GtrA Protein Rv3789 Is Required for Arabinosylation of Arabinogalactan in Mycobacterium tuberculosis

    Article • Journal of Bacteriology, September 2015, ASM Journals

    Stewart Cole

  11. Mode of Action of Clofazimine and Combination Therapy with Benzothiazinones against Mycobacterium tuberculosis

    Article • Antimicrobial Agents and Chemotherapy, May 2015, ASM Journals

    Stewart Cole

  12. The 8-Pyrrole-Benzothiazinones Are Noncovalent Inhibitors of DprE1 from Mycobacterium tuberculosis

    Article • Antimicrobial Agents and Chemotherapy, May 2015, ASM Journals

    Stewart Cole

  13. Bioluminescence for Assessing Drug Potency against Nonreplicating Mycobacterium tuberculosis

    Article • Antimicrobial Agents and Chemotherapy, April 2015, ASM Journals

    Stewart Cole

  14. EspI regulates the ESX‐1 secretion system in response to ATP levels in Mycobacterium tuberculosis

    Article • Molecular Microbiology, July 2014, Wiley

    Dr Neeraj Dhar, Stewart Cole

  15. Who will develop new antibacterial agents?

    Article • Philosophical Transactions of the Royal Society B Biological Sciences, May 2014, Royal Society Publishing

    Stewart Cole

  16. In VitroandIn VivoActivities of Three Oxazolidinones against Nonreplicating Mycobacterium tuberculosis

    Article • Antimicrobial Agents and Chemotherapy, March 2014, ASM Journals

    Stewart Cole

  17. Functional Dissection of Intersubunit Interactions in the EspR Virulence Regulator of Mycobacterium tuberculosis

    Article • Journal of Bacteriology, March 2014, ASM Journals

    Stewart Cole

  18. Cross-Resistance between Clofazimine and Bedaquiline through Upregulation of MmpL5 in Mycobacterium tuberculosis

    Article • Antimicrobial Agents and Chemotherapy, March 2014, ASM Journals

    Stewart Cole

  19. Mechanism of Action of 5-Nitrothiophenes against Mycobacterium tuberculosis

    Article • Antimicrobial Agents and Chemotherapy, February 2014, ASM Journals

    Stewart Cole

  20. Towards a new combination therapy for tuberculosis with next generation benzothiazinones

    Article • EMBO Molecular Medicine, February 2014, EMBO

    Stewart Cole

  21. Tuberculosis drug discovery in the post-post-genomic era

    Article • EMBO Molecular Medicine, January 2014, EMBO

    Stewart Cole

  22. Phenotypic Profiling of Mycobacterium tuberculosis EspA Point Mutants Reveals that Blockage of ESAT-6 and CFP-10 Secretion In Vitro Does Not Always Correlate with Attenuation of Virulence

    Article • Journal of Bacteriology, September 2013, ASM Journals

    Stewart Cole

  23. Structure and function of the transketolase from Mycobacterium tuberculosis and comparison with the human enzyme

    Article • Open Biology, January 2012, Royal Society Publishing

    Stewart Cole