All Stories

  1. Senescence Biomarkers CKAP4 and PTX3 Stratify Severe Kidney Disease Patients
  2. Potential Plasma Proteins (LGALS9, LAMP3, PRSS8 and AGRN) as Predictors of Hospitalisation Risk in COVID-19 Patients
  3. LGALS9, LAMP3, PRSS8 and AGRN Predict Hospitalisation Risk in COVID-19 Patients
  4. Senescence Biomarkers CKAP4 and PTX3 Stratify Severe Kidney Disease Patients
  5. Microsimulation Modelling of Familial Hypercholesterolaemia Inheritance
  6. A comparison of the Netherlands, Norway and UK familial hypercholesterolemia screening programmes with implications for target setting and the UK’s NHS long term plan
  7. The Need for Standardizing Diagnosis, Treatment and Clinical Care of Cholecystitis and Biliary Colic in Gallbladder Disease
  8. The Interdependency and Co-Regulation of the Vitamin D and Cholesterol Metabolism
  9. An Early Stage Researcher's Primer on Systems Medicine Terminology
  10. Improving the Detection of Acute Coronary Syndrome Using Machine Learning of Blood Biomarkers
  11. Deep learning in systems medicine
  12. Opportunities for multiscale computational modelling of serotonergic drug effects in Alzheimer's disease
  13. Network and Systems Medicine: Position Paper of the European Collaboration on Science and Technology Action on Open Multiscale Systems Medicine
  14. An exploratory analysis investigating blood protein biomarkers to augment ECG diagnosis of ACS
  15. Propionibacterium acnes and Acne Vulgaris: New Insights from the Integration of Population Genetic, Multi-Omic, Biochemical and Host-Microbe Studies
  16. New models of atherosclerosis and multi-drug therapeutic interventions
  17. Systems medicine disease maps: community-driven comprehensive representation of disease mechanisms
  18. Role of tumour necrosis factor alpha converting enzyme (TACE/ADAM17) and associated proteins in coronary artery disease and cardiac events
  19. Can we devise new therapies by combining databases of protein interactions and of drug targets?
  20. Coincidence versus consequence: opportunities in multi-morbidity research and inflammation as a pervasive feature
  21. Gap widens for honorary PhDs
  22. The genetics and screening of familial hypercholesterolaemia
  23. An Interferon Regulated MicroRNA Provides Broad Cell-Intrinsic Antiviral Immunity through Multihit Host-Directed Targeting of the Sterol Pathway
  24. Computational modelling of atherosclerosis
  25. Rapid proteasomal elimination of 3-hydroxy-3-methylglutaryl-CoA reductase by interferon-
  26. A comprehensive machine-readable view of the mammalian cholesterol biosynthesis pathway
  27. A model of flux regulation in the cholesterol biosynthesis pathway: Immune mediated graduated flux reduction versus statin-like led stepped flux reduction
  28. The Transcription Factor STAT-1 Couples Macrophage Synthesis of 25-Hydroxycholesterol to the Interferon Antiviral Response
  29. Digital clocks: simple Boolean models can quantitatively describe circadian systems
  30. Host Defense against Viral Infection Involves Interferon Mediated Down-Regulation of Sterol Biosynthesis
  31. The in silico macrophage: toward a better understanding of inflammatory disease
  32. Use of logic theory in understanding regulatory pathway signaling in response to infection
  33. Construction of a large scale integrated map of macrophage pathogen recognition and effector systems
  34. The Systems Biology Graphical Notation
  35. Logic models of pathway biology
  36. Inferring Boolean networks with perturbation from sparse gene expression data: a general model applied to the interferon regulatory network