All Stories

  1. Giardia increases macrophage production of the anti-inflammatory cytokine interleukin-10 in response to lipopolysaccharide via macrophage galactose binding lectin

    Article • ImmunoHorizons, May 2025, Oxford University Press (OUP)

    Professor Steven Singer

  2. Giardia Increases Macrophage Production of the Anti-Inflammatory Cytokine Interleukin-10 in Response to Lipopolysaccharide via Macrophage Galactose Binding Lectin (MGL1)

    Article • April 2024, Cold Spring Harbor Laboratory Press

    Professor Steven Singer

  3. Giardiasis Alters Intestinal Fatty Acid Binding Protein (I-FABP) and Plasma Cytokines Levels in Children in Brazil

    Article • Pathogens, December 2019, MDPI AG

    Professor Steven Singer

  4. Proliferation of Resident Macrophages Is Dispensable for Protection during Giardia duodenalis Infections

    Article • ImmunoHorizons, August 2019, The American Association of Immunologists

    Professor Steven Singer

  5. Recent advances in the Giardia–host relationship reveal danger lurking behind the smile

    Article • PLoS Neglected Tropical Diseases, September 2018, PLOS

    Professor Steven Singer

  6. Giardia Alters Commensal Microbial Diversity throughout the Murine Gut

    Article • Infection and Immunity, April 2017, ASM Journals

    Professor Steven Singer

  7. Adaptive immune response in symptomatic and asymptomatic enteric protozoal infection: evidence for a determining role of parasite genetic heterogeneity in host immunity to human giardiasis

    Article • Microbes and Infection, November 2016, Elsevier

    Professor Steven Singer

  8. Genotyping and Descriptive Proteomics of a Potential Zoonotic Canine Strain of Giardia duodenalis, Infective to Mice

    Article • PLOS One, October 2016, PLOS

    Professor Steven Singer

  9. The Microbiota Contributes to CD8+T Cell Activation and Nutrient Malabsorption following Intestinal Infection with Giardia duodenalis

    Article • Infection and Immunity, July 2016, ASM Journals

    Professor Steven Singer

  10. Complement Activation by Giardia duodenalis Parasites through the Lectin Pathway Contributes to Mast Cell Responses and Parasite Control

    Article • Infection and Immunity, February 2016, ASM Journals

    Professor Steven Singer

  11. The IL-12 Response of Primary Human Dendritic Cells and Monocytes to Toxoplasma gondii Is Stimulated by Phagocytosis of Live Parasites Rather Than Host Cell Invasion

    Article • The Journal of Immunology, November 2015, The American Association of Immunologists

    Professor Steven Singer

  12. Control of Giardiasis by Interleukin-17 in Humans and Mice—Are the Questions All Answered?

    Article • Clinical and Vaccine Immunology, November 2015, ASM Journals

    Professor Steven Singer

  13. Macrophages expressing arginase 1 and nitric oxide synthase 2 accumulate in the small intestine during Giardia lamblia infection

    Article • Microbes and Infection, June 2015, Elsevier

    Professor Steven Singer

  14. Resistance to reinfection in mice as a vaccine model for giardiasis

    Article • Human Vaccines & Immunotherapeutics, May 2014, Taylor & Francis

    Professor Steven Singer

  15. Transcriptomic Analysis of the Host Response to Giardia duodenalis Infection Reveals Redundant Mechanisms for Parasite Control

    Article • mBio, November 2013, ASM Journals

    Professor Steven Singer

  16. Persistent G. lamblia impairs growth in a murine malnutrition model

    Article • Journal of Clinical Investigation, May 2013, American Society for Clinical Investigation

    Professor Steven Singer

  17. Regulation of intestinal epithelial cell cytoskeletal remodeling by cellular immunity following gut infection

    Article • Mucosal Immunology, August 2012, Nature

    Professor Steven Singer

  18. Diplomonadida: Giardia

    Article • August 2012, Wiley

    Professor Steven Singer

  19. Giardia duodenalis: Dendritic cell defects in IL-6 deficient mice contribute to susceptibility to intestinal infection

    Article • Experimental Parasitology, March 2012, Elsevier

    Professor Steven Singer

  20. Host Immunity and Pathogen Strain Contribute to Intestinal Disaccharidase Impairment following Gut Infection

    Article • The Journal of Immunology, August 2011, The American Association of Immunologists

    Professor Steven Singer

  21. Immunology of Giardiasis

    Article • January 2011, Springer Science + Business Media

    Professor Steven Singer

  22. Giardia duodenalis: The double-edged sword of immune responses in giardiasis

    Article • Experimental Parasitology, November 2010, Elsevier

    Professor Steven Singer

  23. A Meta-analysis of the Effectiveness of Albendazole Compared with Metronidazole as Treatments for Infections with Giardia duodenalis

    Article • PLoS Neglected Tropical Diseases, May 2010, PLOS

    Professor Steven Singer

  24. Phosphoinositide 3-Kinase-Dependent Inhibition of Dendritic Cell Interleukin-12 Production by Giardia lamblia

    Article • Infection and Immunity, December 2008, ASM Journals

    Professor Steven Singer

  25. Mast Cell-Mediated Changes in Smooth Muscle Contractility during Mouse Giardiasis

    Article • Infection and Immunity, July 2007, ASM Journals

    Professor Steven Singer

  26. Tumour necrosis factor ? contributes to protection against Giardia lamblia infection in mice

    Article • Parasite Immunology, July 2007, Wiley

    Professor Steven Singer

  27. Epigenetic mechanisms are involved in the control of Giardia lamblia antigenic variation

    Article • Molecular Microbiology, September 2006, Wiley

    Professor Steven Singer

  28. Neuronal Nitric Oxide Synthase Is Necessary for Elimination of Giardia lamblia Infections in Mice

    Article • The Journal of Immunology, December 2005, The American Association of Immunologists

    Professor Steven Singer

  29. Yeast-like mRNA Capping Apparatus in Giardia lamblia

    Article • Journal of Biological Chemistry, November 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Steven Singer

  30. Mast Cell-Dependent Control of Giardia lamblia Infections in Mice

    Article • Infection and Immunity, November 2004, ASM Journals

    Professor Steven Singer

  31. Role of Interleukin-6 in the Control of Acute and Chronic Giardia lamblia Infections in Mice

    Article • Infection and Immunity, March 2003, ASM Journals

    Professor Steven Singer

  32. The abundance of sterile transcripts in Giardia lamblia

    Article • Nucleic Acids Research, November 2001, Oxford University Press (OUP)

    Professor Steven Singer

  33. Initiator and upstream elements in the α2-tubulin promoter of Giardia lamblia

    Article • Molecular and Biochemical Parasitology, March 2001, Elsevier

    Professor Steven Singer

  34. Biological Selection of Variant‐Specific Surface Proteins in Giardia lamblia

    Article • The Journal of Infectious Diseases, January 2001, Oxford University Press (OUP)

    Professor Steven Singer

  35. Lipophosphoglycan is a virulence factor distinct from related glycoconjugates in the protozoan parasiteLeishmania major

    Article • Proceedings of the National Academy of Sciences, July 2000, Proceedings of the National Academy of Sciences

    Professor Steven Singer

  36. The Role of Normal Flora in Giardia lamblia Infections in Mice

    Article • The Journal of Infectious Diseases, April 2000, Oxford University Press (OUP)

    Professor Steven Singer

  37. Targeting of proteins to the nuclei of Giardia lamblia

    Article • Molecular and Biochemical Parasitology, March 2000, Elsevier

    Professor Steven Singer

  38. T-Cell-Dependent Control of Acute Giardia lamblia Infections in Mice

    Article • Infection and Immunity, January 2000, ASM Journals

    Professor Steven Singer

  39. Prevention of diabetes in NOD mice by a mutated I-Ab transgene

    Article • Diabetes, October 1998, American Diabetes Association

    Professor Steven Singer

  40. Episomal and integrated maintenance of foreign DNA in Giardia lamblia

    Article • Molecular and Biochemical Parasitology, April 1998, Elsevier

    Professor Steven Singer

  41. Reduction in Diabetes Incidence in an I-Ag7Transgenic Nonobese Diabetic Mouse Line

    Article • Diabetes, December 1997, American Diabetes Association

    Professor Steven Singer

  42. High copy number I-Ab transgenes induce production of IgE through an interluekin 4-dependent mechanism.

    Article • Proceedings of the National Academy of Sciences, April 1996, Proceedings of the National Academy of Sciences

    Professor Steven Singer

  43. Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases

    Article • Immunology Today, January 1995, Elsevier

    Professor Steven Singer

  44. Effect of tumor necrosis factor alpha on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and the diabetogenic process

    Article • Journal of Experimental Medicine, September 1994, Rockefeller University Press

    Professor Steven Singer

  45. Isolation of Nonobese Diabetic Mouse T-Cells That Recognize Novel Autoantigens Involved in the Early Events of Diabetes

    Article • Diabetes, January 1994, American Diabetes Association

    Professor Steven Singer

  46. Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice

    Article • Nature, November 1993, Nature

    Professor Steven Singer

  47. An Abd transgene prevents diabetes in nonobese diabetic mice by inducing regulatory T cells.

    Article • Proceedings of the National Academy of Sciences, October 1993, Proceedings of the National Academy of Sciences

    Professor Steven Singer

  48. Immune response to Giardia infection: lessons from animal models.

    Article • CABI Publishing

    Professor Steven Singer