All Stories

  1. A Complete 3D-Printed Multiscale Tracheobronchial Tree for Aerosol Deposition Assessment

    Article • European Journal of Pharmaceutical Sciences, February 2026, Elsevier

    Professor Stavros Kassinos

  2. Quantifying the effects of mucociliary clearance and cilia–drug interactions on partial drug dissolution and epithelial deposition in the airway surface liquid

    Article • International Journal of Pharmaceutics, January 2026, Elsevier

    Professor Stavros Kassinos

  3. <p>Assessment of Performance of Two-Phase Solvers for Surface Tension Dominated Flows Related to Lung Airways</p>

    Article • January 2026, Elsevier

    Professor Stavros Kassinos

  4. Beyond language: Applying MLX transformers to engineering physics

    Article • Results in Engineering, June 2025, Elsevier

    Professor Stavros Kassinos

  5. iBCS: 4. Application of the Inhalation Biopharmaceutics Classification System to the Development of Orally Inhaled Drug Products

    Article • Molecular Pharmaceutics, March 2025, American Chemical Society (ACS)

    Professor Stavros Kassinos

  6. Multiscale Modeling of Respiratory Transport Phenomena and Intersubject Variability

    Article • Annual Review of Fluid Mechanics, January 2025, Annual Reviews

    Professor Stavros Kassinos

  7. iBCS: 3. A Biopharmaceutics Classification System for Orally Inhaled Drug Products

    Article • Molecular Pharmaceutics, December 2023, American Chemical Society (ACS)

    Professor Stavros Kassinos

  8. In vitro–in silico correlation of three-dimensional turbulent flows in an idealized mouth-throat model

    Article • PLoS Computational Biology, March 2023, PLOS

    Professor Stavros Kassinos

  9. Fate of inhaled aerosols under the influence of glottal motion in a realistic in silico human tracheobronchial tree model

    Article • European Journal of Pharmaceutical Sciences, June 2022, Elsevier

    Professor Stavros Kassinos

  10. iBCS: 2. Mechanistic Modeling of Pulmonary Availability of Inhaled Drugs versus Critical Product Attributes

    Article • Molecular Pharmaceutics, May 2022, American Chemical Society (ACS)

    Professor Stavros Kassinos

  11. iBCS: 1. Principles and Framework of an Inhalation-Based Biopharmaceutics Classification System

    Article • Molecular Pharmaceutics, May 2022, American Chemical Society (ACS)

    Professor Stavros Kassinos

  12. On the Validation of Generational Lung Deposition Computer Models Using Planar Scintigraphic Images: The Case of Mimetikos Preludium

    Article • Journal of Aerosol Medicine and Pulmonary Drug Delivery, April 2021, Mary Ann Liebert Inc

    Professor Stavros Kassinos

  13. Anatomical variability in the upper tracheobronchial tree: sex-based differences and implications for personalized inhalation therapies

    Article • Journal of Applied Physiology, March 2021, American Physiological Society

    Professor Stavros Kassinos

  14. In silico methods to model dose deposition

    Article • January 2021, Elsevier

    Professor Stavros Kassinos

  15. Inhaled Medicines

    Article • January 2021, Elsevier

    Professor Stavros Kassinos

  16. Introduction

    Article • January 2021, Elsevier

    Professor Stavros Kassinos

  17. Machine learning and in silico methods

    Article • January 2021, Elsevier

    Professor Stavros Kassinos

  18. The emerging state of the art

    Article • January 2021, Elsevier

    Professor Stavros Kassinos

  19. In silico optimization of targeted aerosol delivery in upper airways via Inhaled Volume Tracking

    Article • Clinical Biomechanics, December 2020, Elsevier

    Professor Stavros Kassinos

  20. Towards whole-lung simulations of aerosol deposition: A model of the deep lung

    Article • Journal of Aerosol Science, June 2020, Elsevier

    Professor Stavros Kassinos

  21. Structure-based transient models for scalar dissipation rate in homogeneous turbulence

    Article • International Journal of Heat and Fluid Flow, April 2020, Elsevier

    Professor Stavros Kassinos

  22. In Silico Optimization of Fiber-Shaped Aerosols in Inhalation Therapy for Augmented Targeting and Deposition across the Respiratory Tract

    Article • Pharmaceutics, March 2020, MDPI AG

    Professor Stavros Kassinos

  23. Multiscale in silico Lung Modeling Strategies for Aerosol Inhalation Therapy and Drug Delivery

    Article • Current Opinion in Biomedical Engineering, November 2019, Elsevier

    Professor Stavros Kassinos

  24. Targeting inhaled fibers to the pulmonary acinus: Opportunities for augmented delivery from in silico simulations

    Article • European Journal of Pharmaceutical Sciences, September 2019, Elsevier

    Professor Stavros Kassinos

  25. PIV measurements of the SimInhale benchmark case

    Article • European Journal of Pharmaceutical Sciences, May 2019, Elsevier

    Professor Stavros Kassinos

  26. Phase lock-on in periodically excited Bingham flow past a confined cylinder

    Article • Journal of Non-Newtonian Fluid Mechanics, April 2019, Elsevier

    Professor Stavros Kassinos

  27. Targeting inhaled aerosol delivery to upper airways in children: Insight from computational fluid dynamics (CFD)

    Article • PLOS One, November 2018, PLOS

    Professor Stavros Kassinos

  28. Targeted Drug Delivery to Upper Airways Using a Pulsed Aerosol Bolus and Inhaled Volume Tracking Method

    Article • Flow Turbulence and Combustion, May 2018, Springer Science + Business Media

    Professor Stavros Kassinos

  29. Discrete multi-physics simulations of diffusive and convective mass transfer in boundary layers containing motile cilia in lungs

    Article • Computers in Biology and Medicine, February 2018, Elsevier

    Professor Stavros Kassinos

  30. The feasibility of using in silico model throats for population studies of regional drug deposition

    Article • Journal of Aerosol Science, December 2017, Elsevier

    Professor Stavros Kassinos

  31. Particle-Laden Flow in a Physiologically Realistic Human Airway Bifurcation

    Article • October 2017, Springer Science + Business Media

    Professor Stavros Kassinos

  32. The Effect of Flow Rate and Electrostatic Charge on Aerosol Deposition in a Realistic Lung Geometry

    Article • October 2017, Springer Science + Business Media

    Professor Stavros Kassinos

  33. Editorial on the Special Issue “SimInhale”

    Article • European Journal of Pharmaceutical Sciences, October 2017, Elsevier

    Professor Stavros Kassinos

  34. Are we are doing it right?: benchmarking simulations of regional aerosol deposition in the lungs.

    Article • European Journal of Pharmaceutical Sciences, September 2017, Elsevier

    Professor Stavros Kassinos

  35. Estimating drug deposition in the deep lung: perhaps we can do better than traditional 1D models

    Article • European Journal of Pharmaceutical Sciences, September 2017, Elsevier

    Professor Stavros Kassinos

  36. Transport of ellipsoid fibers in oscillatory shear flows: Implications for aerosol deposition in deep airways

    Article • European Journal of Pharmaceutical Sciences, September 2017, Elsevier

    Professor Stavros Kassinos, Alessandro De Rosis

  37. The contribution of active and inactive structures to the statistics of a turbulent pipe flow

    Article • International Journal of Heat and Fluid Flow, August 2017, Elsevier

    Professor Stavros Kassinos

  38. A review of flow and aerosol measurements in human airways

    Article • European Journal of Pharmaceutical Sciences, August 2017, Elsevier

    Professor Stavros Kassinos

  39. A structure-based model for transport in stably stratified homogeneous turbulent flows

    Article • International Journal of Heat and Fluid Flow, December 2016, Elsevier

    Professor Stavros Kassinos

  40. Vorticity crawlers and other strange animals in near wall turbulence

    Article • Computers & Fluids, October 2016, Elsevier

    Professor Stavros Kassinos

  41. A detailed look at deposition in a human airway bifurcation

    Article • International Journal of Heat and Fluid Flow, September 2016, Elsevier

    Professor Stavros Kassinos

  42. A structure-based model for the transport of passive scalars in homogeneous turbulent flows

    Article • International Journal of Heat and Fluid Flow, February 2016, Elsevier

    Professor Stavros Kassinos

  43. Particle deposition in a realistic geometry of the human conducting airways: Effects of inlet velocity profile, inhalation flowrate and electrostatic charge

    Article • Journal of Biomechanics, November 2015, Elsevier

    Professor Stavros Kassinos

  44. On the transition to turbulence of a viscoplastic fluid past a confined cylinder: A numerical study

    Article • International Journal of Heat and Fluid Flow, October 2015, Elsevier

    Professor Stavros Kassinos

  45. Computation of Complex Terrain Turbulent Flows Using Hybrid Algebraic Structure-Based Models (ASBM) and LES

    Article • August 2015, Springer Science + Business Media

    Professor Stavros Kassinos

  46. The ASBM-SA turbulence closure: Taking advantage of structure-based modeling in current engineering CFD codes

    Article • International Journal of Heat and Fluid Flow, April 2015, Elsevier

    Professor Stavros Kassinos

  47. A general framework for computing the turbulence structure tensors

    Article • Computers & Fluids, January 2015, Elsevier

    Professor Stavros Kassinos

  48. Using Coarrays to Parallelize Legacy Fortran Applications: Strategy and Case Study

    Article • Scientific Programming, January 2015, Hindawi Publishing Corporation

    Professor Stavros Kassinos

  49. Direct numerical simulation of turbulent liquid metal flow entering a magnetic field

    Article • Fusion Engineering and Design, December 2013, Elsevier

    Professor Stavros Kassinos

  50. A consistent velocity approximation for variable-density flow and transport in porous media

    Article • Journal of Hydrology, December 2013, Elsevier

    Professor Stavros Kassinos

  51. Three-dimensional numerical simulations of magnetohydrodynamic flow around a confined circular cylinder under low, moderate, and strong magnetic fields

    Article • Physics of Fluids, July 2013, American Institute of Physics

    Professor Stavros Kassinos

  52. Test-driven coarray parallelization of a legacy Fortran application

    Article • January 2013, ACM (Association for Computing Machinery)

    Professor Stavros Kassinos

  53. Dispersed-phase structure in sheared MHD turbulence

    Article • Journal of Turbulence, January 2012, Taylor & Francis

    Professor Stavros Kassinos

  54. Advances in Particle Representation Modeling of Homogeneous Turbulence. From the Linear PRM Version to the Interacting Viscoelastic IPRM

    Article • January 2012, Springer Science + Business Media

    Professor Stavros Kassinos

  55. Three dimensional flow around a circular cylinder confined in a plane channel

    Article • Physics of Fluids, June 2011, American Institute of Physics

    Professor Stavros Kassinos

  56. Numerical simulation of a liquid-metal flow in a poorly conducting pipe subjected to a strong fringing magnetic field

    Article • Physics of Fluids, April 2011, American Institute of Physics

    Professor Stavros Kassinos

  57. Effects of the consistency of the fringing magnetic field on direct numerical simulations of liquid–metal flow

    Article • Fusion Engineering and Design, January 2011, Elsevier

    Professor Stavros Kassinos

  58. ASBM-BSL: An Easy Access to the Structure Based Model Technology

    Article • January 2011, Springer Science + Business Media

    Professor Stavros Kassinos

  59. MHD flow past a circular cylinder using the immersed boundary method

    Article • Computers & Fluids, February 2010, Elsevier

    Professor Stavros Kassinos

  60. On the use of the BLYP functional for the DFT calculation of graphite–hydrogen systems

    Article • Journal of Nuclear Materials, January 2010, Elsevier

    Professor Stavros Kassinos

  61. Diagnostic Properties of Structure Tensors in Turbulent Flows

    Article • January 2010, Springer Science + Business Media

    Professor Stavros Kassinos

  62. Core of the magnetic obstacle

    Article • Journal of Turbulence, January 2010, Taylor & Francis

    Professor Stavros Kassinos

  63. Preface

    Article • Flow Turbulence and Combustion, October 2009, Springer Science + Business Media

    Professor Stavros Kassinos

  64. CFD modeling of turbulent flow and particle deposition in human lungs

    Article • September 2009, Institute of Electrical & Electronics Engineers (IEEE)

    Professor Stavros Kassinos

  65. On the analogy between streamlined magnetic and solid obstacles

    Article • Physics of Fluids, September 2009, American Institute of Physics

    Professor Stavros Kassinos

  66. Direct simulation of the limiting flux: I. Interpretation of the experimental results

    Article • Journal of Membrane Science, July 2009, Elsevier

    Professor Stavros Kassinos

  67. CFD Analysis of Turbulent Particle Deposition in the Lungs

    Article • June 2009, ASME International

    Professor Stavros Kassinos

  68. Analytic models of heterogenous magnetic fields for liquid metal flow simulations

    Article • Theoretical and Computational Fluid Dynamics, June 2009, Springer Science + Business Media

    Professor Stavros Kassinos

  69. Lagrangian particle dispersion in turbulent flow over a wall mounted obstacle

    Article • International Journal of Heat and Fluid Flow, June 2009, Elsevier

    Professor Stavros Kassinos

  70. Immersed boundary method for the MHD flows of liquid metals

    Article • Journal of Computational Physics, February 2009, Elsevier

    Professor Stavros Kassinos

  71. Numerical Modeling of Turbulent Airflow and Particle Deposition in a Bifurcating Airway Model

    Article • January 2009, Springer Science + Business Media

    Professor Stavros Kassinos

  72. Molecular Simulation of Water in Carbon Nanotubes

    Article • Chemical Reviews, December 2008, American Chemical Society (ACS)

    Professor Stavros Kassinos

  73. Representing anisotropy of two-point second-order turbulence velocity correlations using structure tensors

    Article • Physics of Fluids, October 2008, American Institute of Physics

    Professor Stavros Kassinos

  74. Molecular dynamic simulations of carbon nanotubes in CO2 atmosphere

    Article • Chemical Physics Letters, July 2008, Elsevier

    Professor Stavros Kassinos

  75. Self-diffusivity, hydrogen bonding and density of different water models in carbon nanotubes

    Article • Molecular Simulation, June 2008, Taylor & Francis

    Professor Stavros Kassinos

  76. Influence of water model and nanotube rigidity on the density of water in carbon nanotubes

    Article • Chemical Engineering Science, May 2008, Elsevier

    Professor Stavros Kassinos

  77. The density of water in carbon nanotubes

    Article • Chemical Engineering Science, April 2008, Elsevier

    Professor Stavros Kassinos

  78. Assessing the Impact of Concentration-Dependent Fluid Properties on Concentration Polarization in Crossflow Membrane Systems

    Article • Industrial & Engineering Chemistry Research, March 2008, American Chemical Society (ACS)

    Professor Stavros Kassinos

  79. Dispersed-phase structural anisotropy in homogeneous magnetohydrodynamic turbulence at low magnetic Reynolds number

    Article • Physics of Fluids, February 2008, American Institute of Physics

    Professor Stavros Kassinos

  80. Effects of selective water withdrawal schemes on thermal stratification in Kouris Dam in Cyprus

    Article • Lakes & Reservoirs Science Policy and Management for Sustainable Use, January 2008, Wiley

    Professor Stavros Kassinos

  81. A grid-free abstraction of the Navier-Stokes equations in Fortran 95/2003

    Article • ACM Transactions on Mathematical Software, January 2008, ACM (Association for Computing Machinery)

    Professor Stavros Kassinos

  82. Linear analysis of generalized turbulent hyperbolic flow in a rotating frame

    Article • Physics of Fluids, December 2007, American Institute of Physics

    Professor Stavros Kassinos

  83. Large-eddy simulations of the turbulent Hartmann flow close to the transitional regime

    Article • Physics of Fluids, August 2007, American Institute of Physics

    Professor Stavros Kassinos

  84. On the linear stability of turbulent plane strain flow in a rotating frame

    Article • Physics of Fluids, July 2007, American Institute of Physics

    Professor Stavros Kassinos

  85. Rapidly sheared homogeneous stratified turbulence in a rotating frame

    Article • Physics of Fluids, February 2007, American Institute of Physics

    Professor Stavros Kassinos

  86. Rapid shear of initially anisotropic turbulence in a rotating frame

    Article • Physics of Fluids, February 2007, American Institute of Physics

    Professor Stavros Kassinos

  87. The transport of a passive scalar in magnetohydrodynamic turbulence subjected to mean shear and frame rotation

    Article • Physics of Fluids, January 2007, American Institute of Physics

    Professor Stavros Kassinos

  88. Complex Effects in Large Eddy Simulations

    Article • January 2007, Springer Science + Business Media

    Professor Stavros Kassinos

  89. Assessing the Accuracy of Wall Concentration Estimation Based on Averaged Permeate Velocity in Spacer-Filled Reverse Osmosis (RO) Membrane Systems

    Article • Industrial & Engineering Chemistry Research, November 2006, American Chemical Society (ACS)

    Professor Stavros Kassinos

  90. An analytical solution for rapidly distorted turbulent shear flow in a rotating frame

    Article • Physics of Fluids, August 2006, American Institute of Physics

    Professor Stavros Kassinos

  91. A simplified structure-based model using standard turbulence scale equations: computation of rotating wall-bounded flows

    Article • International Journal of Heat and Fluid Flow, August 2006, Elsevier

    Professor Stavros Kassinos

  92. Statistical measures of structural anisotropy in MHD turbulence subjected to mean shear and frame rotation

    Article • Journal of Turbulence, January 2006, Taylor & Francis

    Professor Stavros Kassinos

  93. Wetting of doped carbon nanotubes by water droplets

    Article • Chemical Physics Letters, September 2005, Elsevier

    Professor Stavros Kassinos

  94. Application of a New Algebraic Structure-Based Model to Rotating Turbulent Flows

    Article • January 2005, Elsevier

    Professor Stavros Kassinos

  95. Magnetohydrodynamic turbulence at moderate magnetic Reynolds number

    Article • Journal of Fluid Mechanics, August 2004, Cambridge University Press

    Professor Stavros Kassinos

  96. Flow of Aqueous Solutions in Carbon Nanotubes

    Article • January 2004, Springer Science + Business Media

    Professor Stavros Kassinos

  97. Thermal Conduction in Magnetized Turbulent Gas

    Article • The Astrophysical Journal, May 2003, Institute of Physics Publishing

    Professor Stavros Kassinos

  98. Structure-based turbulence model: Application to a rotating pipe flow

    Article • Physics of Fluids, April 2002, American Institute of Physics

    Professor Stavros Kassinos

  99. Structure and scales in turbulence modeling

    Article • Physics of Fluids, January 2002, American Institute of Physics

    Professor Stavros Kassinos

  100. One-point turbulence structure tensors

    Article • Journal of Fluid Mechanics, February 2001, Cambridge University Press

    Professor Stavros Kassinos

  101. Structure-based turbulence modeling for wall-bounded flows

    Article • International Journal of Heat and Fluid Flow, October 2000, Elsevier

    Professor Stavros Kassinos

  102. Developments in Structure-Based Turbulence Modeling

    Article • January 1999, Springer Science + Business Media

    Professor Stavros Kassinos

  103. Linear dependencies in fourth-rank turbulence tensor models

    Article • Applied Mathematics Letters, September 1998, Elsevier

    Professor Stavros Kassinos

  104. One-Point Modelling of Rapidly Deformed Homogeneous Turbulence

    Article • Proceedings of the Royal Society A Mathematical Physical and Engineering Sciences, October 1995, Royal Society Publishing

    Professor Stavros Kassinos

  105. Tensorial volume of turbulence revisited

    Article • Physics of Fluids A Fluid Dynamics, September 1990, American Institute of Physics

    Professor Stavros Kassinos

  106. Modeling of Multipoint Correlations in Turbulent Flows

    Article • Springer Science + Business Media

    Professor Stavros Kassinos

  107. Insights for LES from structure-based turubulence modeling

    Article • Springer Science + Business Media

    Professor Stavros Kassinos