All Stories

  1. Hippocampal CA2 to CA1: A metaplastic switch for memory encoding

    Article • Proceedings of the National Academy of Sciences, September 2025, Proceedings of the National Academy of Sciences

    Dr Sreedharan Sajikumar

  2. Slow Release of Hydrogen Sulfide in CA1 Hippocampal Neurons Rescues Long-Term Synaptic Plasticity and Associativity in an Amyloid-β Induced Model of Alzheimer’s Disease

    Article • Journal of Alzheimer’s Disease, September 2024, IOS Press

    Dr Sreedharan Sajikumar

  3. Modulation of the Ubiquitin-Proteasome System Restores Plasticity in Hippocampal Pyramidal Neurons of the APP/PS1 Alzheimer’s Disease-Like Mice

    Article • Journal of Alzheimer’s Disease, April 2022, IOS Press

    Dr Sreedharan Sajikumar

  4. Epigenetic regulation by G9a/GLP complex ameliorates amyloid-beta 1-42 induced deficits in long-term plasticity and synaptic tagging/capture in hippocampal pyramidal neurons

    Article • Aging Cell, June 2017, Wiley

    Dr Sreedharan Sajikumar

  5. Chelation of hippocampal zinc enhances long-term potentiation and synaptic tagging/capture in CA1 pyramidal neurons of aged rats: implications to aging and memory

    Article • Aging Cell, September 2016, Wiley

    Dr Sreedharan Sajikumar

  6. Inhibition of Histone Deacetylase 3 Restores Amyloid-β Oligomer-Induced Plasticity Deficit in Hippocampal CA1 Pyramidal Neurons

    Article • Journal of Alzheimer’s Disease, March 2016, IOS Press

    Dr Sreedharan Sajikumar

  7. Dopamine

    Article • Hippocampus, August 2015, Wiley

    Dr Sreedharan Sajikumar

  8. Impaired spatial memory and enhanced long-term potentiation in mice with forebrain-specific ablation of the Stim genes

    Article • Frontiers in Behavioral Neuroscience, July 2015, Frontiers

    Dr Sreedharan Sajikumar

  9. Lentiviral silencing of GSK-3β in adult dentate gyrus impairs contextual fear memory and synaptic plasticity

    Article • Frontiers in Behavioral Neuroscience, June 2015, Frontiers

    Dr Sreedharan Sajikumar

  10. Ubiquitin-Proteasome System Inhibition Promotes Long-Term Depression and Synaptic Tagging/Capture

    Article • Cerebral Cortex, April 2015, Oxford University Press (OUP)

    Dr Sreedharan Sajikumar

  11. Synaptic Tagging and Capture

    Article • January 2015, Springer Science + Business Media

    Dr Sreedharan Sajikumar

  12. Metaplasticity of Synaptic Tagging and Capture: Memory Beyond the Circle

    Article • September 2014, Springer Science + Business Media

    Dr Sreedharan Sajikumar

  13. Making Synapses Strong: Metaplasticity Prolongs Associativity of Long-Term Memory by Switching Synaptic Tag Mechanisms

    Article • Cerebral Cortex, October 2012, Oxford University Press (OUP)

    Dr Sreedharan Sajikumar

  14. Dopamine induces LTP differentially in apical and basal dendrites through BDNF and voltage-dependent calcium channels

    Article • Learning & Memory, June 2012, Cold Spring Harbor Laboratory Press

    Dr Sreedharan Sajikumar

  15. Different compartments of apical CA1 dendrites have different plasticity thresholds for expressing synaptic tagging and capture

    Article • Learning & Memory, April 2011, Cold Spring Harbor Laboratory Press

    Dr Sreedharan Sajikumar

  16. Protein kinase M  is essential for the induction and maintenance of dopamine-induced long-term potentiation in apical CA1 dendrites

    Article • Learning & Memory, November 2010, Cold Spring Harbor Laboratory Press

    Dr Sreedharan Sajikumar

  17. Priming of short-term potentiation and synaptic tagging/capture mechanisms by ryanodine receptor activation in rat hippocampal CA1

    Article • Learning & Memory, February 2009, Cold Spring Harbor Laboratory Press

    Dr Sreedharan Sajikumar

  18. Distinct single but not necessarily repeated tetanization is required to induce hippocampal late-LTP in the rat CA1

    Article • Learning & Memory, January 2008, Cold Spring Harbor Laboratory Press

    Dr Sreedharan Sajikumar

  19. Cognitive and emotional information processing: protein synthesis and gene expression

    Article • The Journal of Physiology, October 2007, Wiley

    Dr Sreedharan Sajikumar

  20. Synergistic requirements for the induction of dopaminergic D1/D5-receptor-mediated LTP in hippocampal slices of rat CA1 in vitro

    Article • Neuropharmacology, June 2007, Elsevier

    Dr Sreedharan Sajikumar

  21. Identification of Compartment- and Process-Specific Molecules Required for "Synaptic Tagging" during Long-Term Potentiation and Long-Term Depression in Hippocampal CA1

    Article • Journal of Neuroscience, May 2007, Society for Neuroscience

    Dr Sreedharan Sajikumar

  22. Protein synthesis-dependent long-term functional plasticity: methods and techniques [Curr. Opin. Neuro. 15 (2005) 607]

    Article • Current Opinion in Neurobiology, December 2005, Elsevier

    Dr Sreedharan Sajikumar

  23. Protein synthesis-dependent long-term functional plasticity: methods and techniques

    Article • Current Opinion in Neurobiology, October 2005, Elsevier

    Dr Sreedharan Sajikumar

  24. Synaptic Tagging and Cross-Tagging: The Role of Protein Kinase M  in Maintaining Long-Term Potentiation But Not Long-Term Depression

    Article • Journal of Neuroscience, June 2005, Society for Neuroscience

    Dr Sreedharan Sajikumar

  25. Late-associativity, synaptic tagging, and the role of dopamine during LTP and LTD

    Article • Neurobiology of Learning and Memory, July 2004, Elsevier

    Dr Sreedharan Sajikumar

  26. Resetting of ‘synaptic tags’ is time- and activity-dependent in rat hippocampal CA1in vitro

    Article • Neuroscience, January 2004, Elsevier

    Dr Sreedharan Sajikumar

  27. Anisomycin inhibits the late maintenance of long-term depression in rat hippocampal slices in vitro

    Article • Neuroscience Letters, February 2003, Elsevier

    Dr Sreedharan Sajikumar

  28. Podophyllum hexandrum prevents radiation-induced neuronal damage in postnatal rats exposedin utero

    Article • Phytotherapy Research, January 2003, Wiley

    Dr Sreedharan Sajikumar

  29. Effects of Podophyllum hexandrum on radiation induced delay of postnatal appearance of reflexes and physiological markers in rats irradiated in utero

    Article • Phytomedicine, January 2002, Elsevier

    Dr Sreedharan Sajikumar