All Stories

  1. Juglone as a Natural Quorum Sensing Inhibitor against Pseudomonas aeruginosa pqs-Mediated Virulence and Biofilms

    Article • ACS Pharmacology & Translational Science, January 2024, American Chemical Society (ACS)

    Dr Song Lin Chua

  2. Tiny Worms Use Microbe Iron Signals to Hunt for Prey

    Article • Proceedings of the National Academy of Sciences, January 2024, Proceedings of the National Academy of Sciences

    Song Lin Chua, Dr Song Lin Chua

  3. Dual-species proteomics and targeted intervention of animal-pathogen interactions

    Article • July 2023, Cold Spring Harbor Laboratory Press

    Dr Song Lin Chua

  4. Biofilm formation and virulence potential of carbapenem-resistant Pseudomonas aeruginosa

    Article • The Lancet Microbe, July 2023, Elsevier

    Dr Song Lin Chua

  5. Simultaneous Dissemination of Nanoplastics and Antibiotic Resistance by Nematode Couriers

    Article • Environmental Science & Technology, June 2023, American Chemical Society (ACS)

    Dr Song Lin Chua

  6. Biofilm Potentiates Cancer‐Promoting Effects of Tumor‐Associated Macrophages in a 3D Multi‐Faceted Tumor Model

    Article • Small, February 2023, Wiley

    Dr Song Lin Chua

  7. Multivariate analysis of liquid biopsies for real-time detection of patients with biofilm-associated infections (BAI)

    Article • Chemical Engineering Journal, February 2023, Elsevier

    Dr Song Lin Chua

  8. Oxidative stress induced by Etoposide anti-cancer chemotherapy drives the emergence of tumor-associated bacteria resistance to fluoroquinolones

    Article • Journal of Advanced Research, February 2023, Elsevier

    Dr Song Lin Chua

  9. Shotgun metagenomic sequencing analysis of ocular surface microbiome in Singapore residents with mild dry eye

    Article • Frontiers in Medicine, November 2022, Frontiers

    Dr Song Lin Chua

  10. Bacterial targeted AIE photosensitizers synergistically promote chemotherapy for the treatment of inflammatory cancer

    Article • Chemical Engineering Journal, November 2022, Elsevier

    Dr Song Lin Chua

  11. Microbial–Enzymatic Combinatorial Approach to Capture and Release Microplastics

    Article • Environmental Science & Technology Letters, October 2022, American Chemical Society (ACS)

    Dr Song Lin Chua

  12. Elevated c-di-GMP Levels and Expression of the Type III Secretion System Promote Corneal Infection by Pseudomonas aeruginosa

    Article • Infection and Immunity, August 2022, ASM Journals

    Dr Song Lin Chua

  13. Rapid detection of microorganisms in a fish infection microfluidics platform

    Article • Journal of Hazardous Materials, June 2022, Elsevier

    Dr Song Lin Chua

  14. Prevalence of alcohol-tolerant and antibiotic-resistant bacterial pathogens on public hand sanitizer dispensers

    Article • Journal of Hospital Infection, June 2022, Elsevier

    Dr Song Lin Chua

  15. Biofilm dispersal induced by mechanical cutting leads to heightened foodborne pathogen dissemination

    Article • Food Microbiology, April 2022, Elsevier

    Dr Song Lin Chua

  16. Biofilm matrix cloaks bacterial quorum sensing chemoattractants from predator detection

    Article • The ISME Journal, January 2022, Springer Science + Business Media

    Dr Song Lin Chua

  17. Improved Raman spectroscopy-based approach to assess microplastics in seafood

    Article • Environmental Pollution, November 2021, Elsevier

    Dr Song Lin Chua

  18. Label-free biosensor of phagocytosis for diagnosing bacterial infections

    Article • Biosensors and Bioelectronics, November 2021, Elsevier

    Dr Song Lin Chua

  19. No collateral antibiotic sensitivity by alternating antibiotic pairs

    Article • The Lancet Microbe, November 2021, Elsevier

    Dr Song Lin Chua

  20. The effects of biofilms on tumor progression in a 3D cancer-biofilm microfluidic model

    Article • Biosensors and Bioelectronics, May 2021, Elsevier

    Dr Song Lin Chua

  21. Worm-Based Microfluidic Biosensor for Real-Time Assessment of the Metastatic Status

    Article • Cancers, February 2021, MDPI AG

    Dr Song Lin Chua

  22. Engineering a microbial ‘trap and release’ mechanism for microplastics removal

    Article • Chemical Engineering Journal, January 2021, Elsevier

    Dr Song Lin Chua

  23. Biofilm matrix disrupts nematode motility and predatory behavior

    Article • The ISME Journal, September 2020, Springer Science + Business Media

    Dr Song Lin Chua

  24. Vanillin inhibits PqsR-mediated virulence in Pseudomonas aeruginosa

    Article • Food & Function, January 2020, Royal Society of Chemistry

    Dr Song Lin Chua

  25. Demolishing the great wall of biofilms in Gram‐negative bacteria: To disrupt or disperse?

    Article • Medicinal Research Reviews, November 2019, Wiley

    Dr Song Lin Chua

  26. Low-dose anti-inflammatory combinatorial therapy reduced cancer stem cell formation in patient-derived preclinical models for tumour relapse prevention

    Article • British Journal of Cancer, February 2019, Springer Science + Business Media

    Dr Song Lin Chua

  27. Repurposing the anticancer drug cisplatin with the aim of developing novel Pseudomonas aeruginosa infection control agents

    Article • Beilstein Journal of Organic Chemistry, December 2018, Beilstein Institut

    Dr Song Lin Chua

  28. Reduced Intracellular c-di-GMP Content Increases Expression of Quorum Sensing-Regulated Genes in Pseudomonas aeruginosa

    Article • Frontiers in Cellular and Infection Microbiology, October 2017, Frontiers

    Dr Song Lin Chua

  29. Correction to ‘Reactive oxygen species drive evolution of pro-biofilm variants in pathogens by modulating cyclic-di-GMP levels’

    Article • Open Biology, September 2017, Royal Society Publishing

    Dr Song Lin Chua

  30. In Vitro and In Vivo Efficacy of an LpxC Inhibitor, CHIR-090, Alone or Combined with Colistin against Pseudomonas aeruginosa Biofilm

    Article • Antimicrobial Agents and Chemotherapy, May 2017, ASM Journals

    Dr Song Lin Chua

  31. Proteogenomics ofPseudomonas aeruginosain Cystic Fibrosis Infections

    Article • April 2017, Wiley

    Dr Song Lin Chua

  32. Gauging and Visualizing c-di-GMP Levels in Pseudomonas aeruginosa Using Fluorescence-Based Biosensors

    Article • January 2017, Springer Science + Business Media

    Dr Song Lin Chua

  33. Disulfide Bond-Containing Ajoene Analogues As Novel Quorum Sensing Inhibitors of Pseudomonas aeruginosa

    Article • Journal of Medicinal Chemistry, December 2016, American Chemical Society (ACS)

    Dr Song Lin Chua

  34. Reactive oxygen species drive evolution of pro-biofilm variants in pathogens by modulating cyclic-di-GMP levels

    Article • Open Biology, November 2016, Royal Society Publishing

    Dr Song Lin Chua

  35. Selective labelling and eradication of antibiotic-tolerant bacterial populations in Pseudomonas aeruginosa biofilms

    Article • Nature Communications, February 2016, Nature

    Dr Song Lin Chua

  36. RpoN Regulates Virulence Factors of Pseudomonas aeruginosa via Modulating the PqsR Quorum Sensing Regulator

    Article • International Journal of Molecular Sciences, November 2015, MDPI AG

    Dr Song Lin Chua

  37. PslG, a self-produced glycosyl hydrolase, triggers biofilm disassembly by disrupting exopolysaccharide matrix

    Article • Cell Research, November 2015, Nature

    Dr Song Lin Chua

  38. In vitro and in vivo generation and characterization of Pseudomonas aeruginosa biofilm–dispersed cells via c-di-GMP manipulation

    Article • Nature Protocols, July 2015, Nature

    Dr Song Lin Chua

  39. C-di-GMP regulates Pseudomonas aeruginosa stress response to tellurite during both planktonic and biofilm modes of growth

    Article • Scientific Reports, May 2015, Nature

    Dr Song Lin Chua

  40. Multiple diguanylate cyclase-coordinated regulation of pyoverdine synthesis inPseudomonas aeruginosa

    Article • Environmental Microbiology Reports, April 2015, Wiley

    Dr Song Lin Chua

  41. Comparative Systems Biology Analysis To Study the Mode of Action of the Isothiocyanate Compound Iberin on Pseudomonas aeruginosa

    Article • Antimicrobial Agents and Chemotherapy, August 2014, ASM Journals

    Dr Song Lin Chua

  42. Dispersed cells represent a distinct stage in the transition from bacterial biofilm to planktonic lifestyles

    Article • Nature Communications, July 2014, Nature

    Dr Song Lin Chua

  43. A stable synergistic microbial consortium for simultaneous azo dye removal and bioelectricity generation

    Article • Bioresource Technology, March 2014, Elsevier

    Dr Song Lin Chua

  44. Synergistic Microbial Consortium for Bioenergy Generation from Complex Natural Energy Sources

    Article • The Scientific World JOURNAL, January 2014, Hindawi Publishing Corporation

    Dr Song Lin Chua

  45. Identification of Five Structurally Unrelated Quorum-Sensing Inhibitors of Pseudomonas aeruginosa from a Natural-Derivative Database

    Article • Antimicrobial Agents and Chemotherapy, September 2013, ASM Journals

    Dr Song Lin Chua

  46. Engineering PQS Biosynthesis Pathway for Enhancement of Bioelectricity Production in Pseudomonas aeruginosa Microbial Fuel Cells

    Article • PLoS ONE, May 2013, PLOS

    Dr Enrico Marsili, Dr Song Lin Chua

  47. Comparative Genomic Analysis of Rapid Evolution of an Extreme-Drug-Resistant Acinetobacter baumannii Clone

    Article • Genome Biology and Evolution, March 2013, Oxford University Press (OUP)

    Dr Song Lin Chua

  48. Bis-(3′-5′)-Cyclic Dimeric GMP Regulates Antimicrobial Peptide Resistance in Pseudomonas aeruginosa

    Article • Antimicrobial Agents and Chemotherapy, February 2013, ASM Journals

    Dr Song Lin Chua