All Stories

  1. Inborn Errors of Purine Salvage and Catabolism

    Article • Metabolites, June 2023, MDPI AG

    Simone Allegrini

  2. The Good, the Bad and the New about Uric Acid in Cancer

    Article • Cancers, October 2022, MDPI AG

    Simone Allegrini

  3. Cytosolic 5′-Nucleotidase II Silencing in Lung Tumor Cells Regulates Metabolism through Activation of the p53/AMPK Signaling Pathway

    Article • International Journal of Molecular Sciences, June 2021, MDPI AG

    Simone Allegrini

  4. Cytosolic 5′-Nucleotidase II Is a Sensor of Energy Charge and Oxidative Stress: A Possible Function as Metabolic Regulator

    Article • Cells, January 2021, MDPI AG

    Simone Allegrini

  5. Evidence for a Cross-Talk Between Cytosolic 5′-Nucleotidases and AMP-Activated Protein Kinase

    Article • Frontiers in Pharmacology, December 2020, Frontiers

    Simone Allegrini

  6. Purine-Metabolising Enzymes and Apoptosis in Cancer

    Article • Cancers, September 2019, MDPI AG

    Simone Allegrini

  7. Emerging Role of Purine Metabolizing Enzymes in Brain Function and Tumors

    Article • International Journal of Molecular Sciences, November 2018, MDPI AG

    Simone Allegrini

  8. Cytosolic 5′-Nucleotidase II Silencing in a Human Lung Carcinoma Cell Line Opposes Cancer Phenotype with a Concomitant Increase in p53 Phosphorylation

    Article • International Journal of Molecular Sciences, July 2018, MDPI AG

    Simone Allegrini

  9. Interplay between adenylate metabolizing enzymes and AMP-activated protein kinase

    Article • FEBS Journal, May 2018, Wiley

    Simone Allegrini

  10. Functions of the multi-interacting protein KIDINS220/ARMS in cancer and other pathologies

    Article • Genes Chromosomes and Cancer, December 2017, Wiley

    Muhammad Zawwad RAZA, Simone Allegrini

  11. Cell proliferation and drug sensitivity of human glioblastoma cells are altered by the stable modulation of cytosolic 5′-nucleotidase II

    Article • The International Journal of Biochemistry & Cell Biology, August 2015, Elsevier

    Simone Allegrini

  12. IMP–GMP specific cytosolic 5′-nucleotidase regulates nucleotide pool and prodrug metabolism

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, July 2015, Elsevier

    Simone Allegrini

  13. Cytosolic 5’-Nucleotidase II Interacts with the Leucin Rich Repeat of NLR Family Member Ipaf

    Article • PLoS ONE, March 2015, PLOS

    Simone Allegrini

  14. The purine analog fludarabine acts as a cytosolic 5′-nucleotidase II inhibitor

    Article • Biochemical Pharmacology, March 2015, Elsevier

    Simone Allegrini

  15. On the Physiological Role of Cytosolic 5’-nucleotidase II (cN-II): Pathological and Therapeutical Implications.

    Article • Current Medicinal Chemistry, October 2013, Bentham Science Publishers

    Simone Allegrini

  16. A native electrophoretic technique to study oligomerization and activity of cytosolic 5′-nucleotidase II

    Article • Analytical and Bioanalytical Chemistry, September 2013, Springer Science + Business Media

    Simone Allegrini

  17. Expression of Bovine Cytosolic 5′-Nucleotidase (cN-II) in Yeast: Nucleotide Pools Disturbance and Its Consequences on Growth and Homologous Recombination

    Article • PLoS ONE, May 2013, PLOS

    Simone Allegrini

  18. Novel metabolic aspects related to adenosine deaminase inhibition in a human astrocytoma cell line

    Article • Neurochemistry International, April 2012, Elsevier

    Simone Allegrini

  19. Structural basis of the substrate specificity ofBacillus cereusadenosine phosphorylase

    Article • Acta Crystallographica Section D Biological Crystallography, February 2012, International Union of Crystallography

    Simone Allegrini

  20. Initial Studies to Define the Physiologic Role of cN-II

    Article • Nucleosides Nucleotides & Nucleic Acids, December 2011, Taylor & Francis

    Simone Allegrini

  21. Active and regulatory sites of cytosolic 5′‐nucleotidase

    Article • FEBS Journal, October 2010, Wiley

    Simone Allegrini

  22. Knockdown of cytosolic 5′-nucleotidase II (cN-II) reveals that its activity is essential for survival in astrocytoma cells

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, August 2008, Elsevier

    Simone Allegrini

  23. Characterization of the adenine nucleoside specific phosphorylase of Bacillus cereus

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, October 2007, Elsevier

    Simone Allegrini

  24. Mechanistic studies on bovine cytosolic 5′‐nucleotidase II, an enzyme belonging to the HAD superfamily

    Article • European Journal of Biochemistry, December 2004, Wiley

    Simone Allegrini

  25. 5′-aminoimidazole-4-carboxamide riboside induces apoptosis in human neuroblastoma cells

    Article • Neuroscience, April 2003, Elsevier

    Simone Allegrini

  26. Catabolism of exogenous deoxyinosine in cultured epithelial amniotic cells

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, October 2001, Elsevier

    Dr Mattana A Antonella, Simone Allegrini

  27. Bovine Cytosolic 5′-Nucleotidase Acts through the Formation of an Aspartate 52-Phosphoenzyme Intermediate

    Article • Journal of Biological Chemistry, September 2001, Elsevier

    Simone Allegrini

  28. Cytosolic 5′-nucleotidase hyperactivity in erythrocytes of Lesch–Nyhan syndrome patients

    Article • Neuroreport, June 2000, Wolters Kluwer Health

    Simone Allegrini

  29. Identification, Separation and Characterisation of Two Forms of Cytosolic 5′-Nucleotidase/Nucleoside Phosphotransferase in Calf Thymus

    Article • Biological Chemistry, June 1998, De Gruyter

    Simone Allegrini

  30. Bovine cytosolic IMP/GMP-specific 5′-nucleotidase: cloning and expression of active enzyme in Escherichia coli

    Article • Biochemical Journal, December 1997, Portland Press Ltd.

    Simone Allegrini

  31. Substrates and/or Inhibitors of IMP-GMP Specific Cytosolic 5′-Nucleotidase (cN-II)

    Article • Emerging Therapeutic Targets, January 1997, Informa Healthcare

    Simone Allegrini

  32. The phosphotransferase activity of cytosolic 5′-nucleotidase; a purine analog phosphorylating enzyme

    Article • The International Journal of Biochemistry & Cell Biology, June 1996, Elsevier

    Simone Allegrini

  33. The Bifunctional Cytosolic 5′-Nucleotidase: Regulation of the Phosphotransferase and Nucleotidase Activities

    Article • Archives of Biochemistry and Biophysics, July 1994, Elsevier

    Simone Allegrini

  34. Cytosolic 5′-nucleotidase/nucleoside phosphotransferase: a single assay for a bifunctional enzyme

    Article • Journal of Biochemical and Biophysical Methods, December 1993, Elsevier

    Simone Allegrini

  35. Nucleoside phosphotransferase activity of human colon carcinoma cytosolic 5′-nucleotidase

    Article • Archives of Biochemistry and Biophysics, November 1991, Elsevier

    Simone Allegrini

  36. On the validity of continuous spectrophotometric assays for adenosine deaminase activity: A critical reappraisal

    Article • Analytical Biochemistry, February 1991, Elsevier

    Simone Allegrini

  37. Renal purine efflux and xanthine oxidase activity during experimental nephrosis in rats: Difference between puromycin aminonucleoside and adriamycin nephrosis

    Article • Clinical Science, March 1990, Portland Press Ltd.

    Simone Allegrini