Professor Simon mbua Ngale Efange

ConMedNP: a natural product library from Central African medicinal plants for drug disc...

• RSC Advances
• January 2014

1-Aryl-1,2,3,4-tetrahydroisoquinolines as potential antimalarials: synthesis, in vitro ...

• RSC Advances
• January 2014

How “drug-like” are naturally occurring anti-cancer compounds?

• Journal of Molecular Modeling
• January 2014

AfroDb: A Select Highly Potent and Diverse Natural Product Library from African Medicin...

• PLoS ONE
• October 2013

Isolation and identification of an antiparasitic triterpenoid estersaponin from the ste...

• Asian Pacific Journal of Tropical Disease
• October 2013

In silico drug metabolism and pharmacokinetic profiles of natural products from medicin...

• In Silico Pharmacology
• August 2013

Cameroonian medicinal plants: a bioactivity versus ethnobotanical survey and chemotaxon...

• BMC Complementary and Alternative Medicine
• June 2013

CamMedNP: Building the Cameroonian 3D structural natural products database for virtual ...

• BMC Complementary and Alternative Medicine
• April 2013

Bioactive natural products derived from the Central African flora against neglected tro...

• Natural Product Reports
• January 2013

Assessing the pharmacokinetic profile of the CamMedNP natural products database: an in ...

• Organic and Medicinal Chemistry Letters
• January 2013

Bioassay-guided discovery of antibacterial agents: in vitro screening of Peperomia vulc...

• Annals of Clinical Microbiology and Antimicrobials
• January 2012

ChemInform Abstract: Flexible N-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Analogues: S...

• ChemInform
• August 2010

ChemInform Abstract: Interaction of Tetrahydrostilbazoles with Monoamine Oxidase A and B.

• ChemInform
• August 2010

ChemInform Abstract: Modified Ibogaine Fragments: Synthesis and Preliminary Pharmacolog...

• ChemInform
• June 2010

Synthesis and<i>in Vitro</i>Biological Evaluation of Carbonyl Group-Containing Inhibito...

• Journal of Medicinal Chemistry
• April 2010

UPLC/TOF-MS methodology for the on-line identification of secondary metabolites in four...

• Planta Medica
• July 2009

Synthesis and in Vitro and in Vivo Evaluation of ¹⁸F-Labeled Positron Emissi...

• Journal of Medicinal Chemistry
• February 2009

Okundoperoxide, a Bicyclic Cyclofarnesylsesquiterpene Endoperoxide from <i>Scleria stri...

• Journal of Natural Products
• February 2009

Oxidation Products Arising from the Action of Monoamine Oxidase B on 1-Methyl-4-Benzyl-...

• Journal of Neurochemistry
• June 2008

In vitro anti-Helicobacter pylori activity of extracts of selected medicinal plants fro...

• Journal of Ethnopharmacology
• December 2007

Isolation and structure eucidation of novel antimalarial compounds from the Cameroonian...

• Planta Medica
• January 2007

Nature-inspired indolyl-2-azabicyclo[2.2.2]oct-7-ene derivatives as promising agents fo...

• Natural Product Research
• July 2006

Corporate Governance

• September 2004

Natural Products: A Continuing Source of Inspiration for the Medicinal Chemist

• ChemInform
• July 2003

Ibogaine analogues. Synthesis and preliminary pharmacological evaluation of 7-heteroary...

• Bioorganic & Medicinal Chemistry
• March 2003

Chromaproline and Chromaperidine, nicotine agonists, and Donepezil, cholinesterase inhi...

• Pharmacology Biochemistry and Behavior
• December 2002

Natural products: a continuing source of inspiration for the medicinal chemist

• January 2002

2-(2-Piperidyl)- and 2-(2-Pyrrolidyl)chromans as Nicotine Agonists:  Synthesis and Prel...

• Journal of Medicinal Chemistry
• November 2001

Morphine-induced spinal cholinergic activation: in vivo imaging with positron emission ...

• Pain
• March 2001

In<i>vivo</i>imaging of the vesicular acetylcholine transporter and the vesicular monoa...

• The FASEB Journal
• December 2000

Synthesis and biological characterization of stable and radioiodinated (±)-trans-2-hydr...

• Nuclear Medicine and Biology
• November 2000

Late Shakespeare

• January 2000

Cholinergic activity of aged rhesus monkeys revealed by positron emission tomography

• Synapse
• January 2000

EVesamicolffects of a Novel Vesamicol Receptor Ligand, m-(Iodobenzyl)trozamicol, on the...

• The Japanese Journal of Pharmacology
• January 2000

Direct Cardiac Effects of a Novel Vesamicol Receptor Ligand, m-Iodobenzyl-Trozamicol, A...

• Journal of Cardiovascular Pharmacology
• December 1999

N-(3-iodophenyl)trozamicol (IPHT) and related inhibitors of vesicular acetylcholine tra...

• Nuclear Medicine and Biology
• August 1999

Hydroxylated Decahydroquinolines as Ligands for the Vesicular Acetylcholine Transporter...

• Journal of Medicinal Chemistry
• July 1999

(+)-p-([18F]fluorobenzyl)spirotrozamicol {(+)-[18F]Spiro-FBT}: synthesis and biological...

• Nuclear Medicine and Biology
• February 1999

In Vivo Imaging of the Spinal Cord Cholinergic System with PET

• Journal of Computer Assisted Tomography
• January 1999

Modified Ibogaine Fragments:  Synthesis and Preliminary Pharmacological Characterizatio...

• Journal of Medicinal Chemistry
• September 1998

<i>N</i>-Hydroxyalkyl Derivatives of 3β-Phenyltropane and 1-Methylspiro[1<i>H</i>-indol...

• Journal of Medicinal Chemistry
• November 1997

Pharmacological characterization of the vesamicol analogue (+)-[ ]MIBT in primate brain

• European Journal of Pharmacology
• November 1997

Vesicular Acetylcholine Transporter Density and Alzheimer’s Disease

• Neurobiology of Aging
• July 1997

Imaging of cholinergic terminals using the radiotracer [18F](+)-4-fluorobenzyltrozamico...

• Synapse
• April 1997

Vesicular acetylcholine transport inhibitor suppresses REM sleep

• Neuroreport
• January 1997

Measurement of functional cholinergic innervation in rat heart with a novel vesamicol r...

• Nuclear Medicine and Biology
• October 1996

The vesamicol receptor ligand (+)-meta-[1251]iodobenzyltrozamicol {(+)-[125¦]-MIBT} rev...

• Life Sciences
• March 1996

Comparative tissue distribution of conformationally restricted radioiodinated vesamicol...

• Nuclear Medicine and Biology
• May 1995

Vesamicol analogues as sigma ligands

• Biochemical Pharmacology
• March 1995

Spirovesamicols: Conformationally Restricted Analogs of 2-(4-Phenylpiperidino)cyclohexa...

• Journal of Medicinal Chemistry
• August 1994

p-[18F]fluorobenzyltrozamicol ([18F]FBT): Molecular decomposition-reconstitution approa...

• Applied Radiation and Isotopes
• April 1994

Interaction of tetrahydrostilbazoles with monoamine oxidase A and B

• Journal of Medicinal Chemistry
• January 1994

Synthesis and tissue distribution of iodine-125-labeled (m-[125I]iodobenzyl)trozamicol ...

• Journal of Medicinal Chemistry
• June 1993

Synthesis and biological evaluation of radioiodinated N-2-(4-piperidyl)ethyl benzamides

• Nuclear Medicine and Biology
• May 1993

Nonsymmetrical bipiperidyls as inhibitors of vesicular acetylcholine storage

• Journal of Medicinal Chemistry
• April 1993

Molecular size and flexibility as determinants of selectivity in the oxidation of N-met...

• Journal of Medicinal Chemistry
• April 1993

Lipophilic amino alcohols with calcium channel blocking activity

• Biochemical Pharmacology
• November 1992

Computer-Aided Radiopharmaceutical Design

• Investigative Radiology
• August 1992

Interaction of flexible analogs of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and of ...

• Biochemistry
• June 1992

Radioiodinated 2-hydroxy-3-(4-iodophenyl)-1-(4-phenylpiperidinyl)propane: Potential rad...

• International Journal of Radiation Applications and Instrumentation Part B Nuclear Medi...
• April 1992

Textbook of Radiopharmacy: Theory and Practice

• Radiology
• January 1992

APPLICATIONS OF COMPUTATIONAL CHEMISTRY IN RADIOPHARMACEUTICAL DESIGNE

• Investigative Radiology
• December 1991

APPLICATIONS OF COMPUTATIONAL CHEMISTRY IN RADIOPHARMACEUTICAL DESIGN

• Investigative Radiology
• December 1991

Molecular determinants in the bioactivation of the dopaminergic neurotoxin N-methyl-4-p...

• Journal of Computer-Aided Molecular Design
• October 1991

Synthesis and Biological Activity of 5-halo-2-Pyrimidinone 3′-Azido-2′,3′-Dideoxyribosides

• Nucleosides and Nucleotides
• October 1991

Acyclic analogs of 2-(4-phenylpiperidino)cyclohexanol (vesamicol): conformationally mob...

• Journal of Medicinal Chemistry
• August 1991

Characterization and Distribution of Transferrin Receptors in the Rat Brain

• Journal of Neurochemistry
• December 1990

THE CALCULATED EFFECTS OF N-FLUOROALKYLATION OF RACLOPRIDE ON MOLECULAR CONFORMATION AN...

• Investigative Radiology
• December 1990

Flexible N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine analog: synthesis and monoamine o...

• Journal of Medicinal Chemistry
• December 1990

Synthesis and Applications of Isotopically Labelled Compounds

• Radiology
• August 1990

Potential environmental neurotoxins related to 1-methyl-4-phenylpyridinium: Selective t...

• Experimental Neurology
• May 1990

Pargyline-Sensitive selective accumulation of a radiolabeled MPTP analog in the primate...

• Synapse
• January 1990

Radiopharmacy and Radiopharmacology Yearbook

• Radiology
• November 1989

Selective Visualization of Rodent Locus Ceruleus by a Radiolabeled N-Methyl-4-Phenyl-1,...

• Journal of Neurochemistry
• August 1989

Anti-herpes simplex virus activity of 5-substituted 2-pyrimidinone nucleosides.

• Antimicrobial Agents and Chemotherapy
• March 1989

Synthesis and biodistribution of 99mTc-labeled piperidinyl bis(aminoethanethiol) comple...

• Journal of Medicinal Chemistry
• May 1988

Toxicity of Structural Analogs of 1-methyl-4-Phenyl Pyridinium (MPP+) and Related Compo...

• January 1988

Synthesis and biological activities of 2-Pyrimidinone Nucleosides. III.1,25-Alkynyl-2-P...

• Nucleosides and Nucleotides
• December 1985

Synthesis and biological activities of 2-pyrimidinone nucleosides. 2. 5-Halo-2-pyrimidi...

• Journal of Medicinal Chemistry
• July 1985

Caney, Simon