All Stories

  1. Human Protein HSF2 Helps Wake Up Sleeping Cancer-Linked Viruses

    Article • PLoS Pathogens, April 2025, PLOS

    Silvia Gramolelli

  2. Heat shock factor 2 positively regulates oncogenic herpesvirus gene expression by remodeling the chromatin landscape

    Article • November 2024, Cold Spring Harbor Laboratory Press

    Silvia Gramolelli

  3. Dynamic HSF2 regulation drives breast cancer progression by steering the balance between proliferation and invasion

    Article • June 2024, Cold Spring Harbor Laboratory Press

    Silvia Gramolelli

  4. DLL4/Notch3/WNT5B axis mediates bidirectional prometastatic crosstalk between melanoma and lymphatic endothelial cells

    Article • JCI Insight, January 2024, American Society for Clinical Investigation

    Silvia Gramolelli

  5. Kaposi’s Sarcoma-Associated Herpesvirus Reactivation by Targeting of a dCas9-Based Transcription Activator to the ORF50 Promoter

    Article • Viruses, August 2020, MDPI AG

    Silvia Gramolelli

  6. Oncogenic Herpesvirus Engages Endothelial Transcription Factors SOX18 and PROX1 to Increase Viral Genome Copies and Virus Production

    Article • Cancer Research, August 2020, American Association for Cancer Research (AACR)

    Silvia Gramolelli

  7. Kaposi’s Sarcoma-Associated Herpesvirus Lytic Replication Is Independent of Anaphase-Promoting Complex Activity

    Article • Journal of Virology, June 2020, ASM Journals

    Silvia Gramolelli

  8. HSP70 induces liver X receptor pathway activation and cholesterol reduction in vitro and in vivo

    Article • Molecular Metabolism, October 2019, Elsevier

    Silvia Gramolelli

  9. High tissue MMP14 expression predicts worse survival in gastric cancer, particularly with a low PROX1

    Article • Cancer Medicine, September 2019, Wiley

    Silvia Gramolelli

  10. MMP14 in Sarcoma: A Regulator of Tumor Microenvironment Communication in Connective Tissues

    Article • Cells, August 2019, MDPI AG

    Silvia Gramolelli

  11. Kaposi's Sarcoma-Associated Herpesvirus Nonstructural Membrane Protein pK15 Recruits the Class II Phosphatidylinositol 3-Kinase PI3K-C2α To Activate Productive Viral Replication

    Article • Journal of Virology, June 2018, ASM Journals

    Silvia Gramolelli

  12. PROX1 is a transcriptional regulator of MMP14

    Article • Scientific Reports, June 2018, Springer Science + Business Media

    Silvia Gramolelli

  13. Lymphatic endothelium stimulates melanoma metastasis and invasion via MMP14-dependent Notch3 and β1-integrin activation

    Article • eLife, May 2018, eLife

    Silvia Gramolelli

  14. Kaposi's sarcoma herpesvirus-induced endothelial cell reprogramming supports viral persistence and contributes to Kaposi's sarcoma tumorigenesis

    Article • Current Opinion in Virology, October 2017, Elsevier

    Silvia Gramolelli

  15. Inhibiting the Recruitment of PLCγ1 to Kaposi’s Sarcoma Herpesvirus K15 Protein Reduces the Invasiveness and Angiogenesis of Infected Endothelial Cells

    Article • PLoS Pathogens, August 2015, PLOS

    Silvia Gramolelli

  16. The role of Kaposi sarcoma‐associated herpesvirus in the pathogenesis of Kaposi sarcoma

    Article • The Journal of Pathology, December 2014, Wiley

    Silvia Gramolelli

  17. Absence of the human CYP2C8*3 allele in Ugandan children exposed to Plasmodium falciparum malaria

    Article • Infection Genetics and Evolution, October 2014, Elsevier

    Silvia Gramolelli

  18. Activation of NF- B by the Kaposi's Sarcoma-Associated Herpesvirus K15 Protein Involves Recruitment of the NF- B-Inducing Kinase, I B Kinases, and Phosphorylation of p65

    Article • Journal of Virology, September 2014, ASM Journals

    Silvia Gramolelli

  19. The Inflammatory Kinase MAP4K4 Promotes Reactivation of Kaposi's Sarcoma Herpesvirus and Enhances the Invasiveness of Infected Endothelial Cells

    Article • PLoS Pathogens, November 2013, PLOS

    Silvia Gramolelli

  20. Kaposi's Sarcoma Herpesvirus K15 Protein Contributes to Virus-Induced Angiogenesis by Recruiting PLCγ1 and Activating NFAT1-dependent RCAN1 Expression

    Article • PLoS Pathogens, September 2012, PLOS

    Silvia Gramolelli

  21. Distribution of human CYP2C8*2 allele in three different African populations

    Article • Malaria Journal, April 2012, Springer Science + Business Media

    Silvia Gramolelli