All Stories

  1. DDX3X: stressing the NLRP3 inflammasome

    Article • Cell Research, October 2019, Springer Science + Business Media

    Si Ming Man

  2. A multicomponent toxin from Bacillus cereus incites inflammation and shapes host outcome via the NLRP3 inflammasome

    Article • Nature Microbiology, December 2018, Springer Science + Business Media

    Dr. Kristina Schauer, Si Ming Man

  3. ALPK1: innate attraction to the sweetness of bacteria

    Article • Cell Research, October 2018, Springer Science + Business Media

    Si Ming Man

  4. Cytosolic Recognition of Microbes and Pathogens: Inflammasomes in Action

    Article • Microbiology and Molecular Biology Reviews, September 2018, ASM Journals

    Si Ming Man

  5. Inflammasomes in the gastrointestinal tract: infection, cancer and gut microbiota homeostasis

    Article • Nature Reviews Gastroenterology & Hepatology, September 2018, Springer Science + Business Media

    Si Ming Man

  6. Mechanisms of Gasdermin Family Members in Inflammasome Signaling and Cell Death

    Article • Journal of Molecular Biology, September 2018, Elsevier

    Si Ming Man

  7. Mechanisms and functions of guanylate-binding proteins and related interferon-inducible GTPases: Roles in intracellular lysis of pathogens

    Article • Cellular Microbiology, October 2017, Wiley

    Si Ming Man

  8. Molecular mechanisms of inflammasome signaling

    Article • Journal of Leukocyte Biology, August 2017, Wiley

    Si Ming Man

  9. NLRP9b: a novel RNA-sensing inflammasome complex

    Article • Cell Research, July 2017, Springer Science + Business Media

    Si Ming Man

  10. Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases

    Article • Immunological Reviews, April 2017, Wiley

    Si Ming Man

  11. Differential roles of caspase-1 and caspase-11 in infection and inflammation

    Article • Scientific Reports, March 2017, Springer Science + Business Media

    Si Ming Man

  12. Inflammasomes and Cancer

    Article • Cancer Immunology Research, January 2017, American Association for Cancer Research (AACR)

    Si Ming Man

  13. Regulation of lysosomal dynamics and autophagy by CTSB/cathepsin B

    Article • Autophagy, October 2016, Taylor & Francis

    Si Ming Man

  14. IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes

    Article • Cell, October 2016, Elsevier

    Si Ming Man

  15. Cathepsin B modulates lysosomal biogenesis and host defense against Francisella novicida infection

    Article • The Journal of Experimental Medicine, August 2016, Rockefeller University Press

    Si Ming Man

  16. Interferon-inducible guanylate-binding proteins at the interface of cell-autonomous immunity and inflammasome activation

    Article • Journal of Leukocyte Biology, July 2016, Wiley

    Si Ming Man

  17. DOCK2 confers immunity and intestinal colonization resistance to Citrobacter rodentium infection

    Article • Scientific Reports, June 2016, Springer Science + Business Media

    Si Ming Man

  18. DNA-sensing inflammasomes: regulation of bacterial host defense and the gut microbiota

    Article • Pathogens and Disease, April 2016, Oxford University Press (OUP)

    Si Ming Man

  19. Type I Interferon Keeps IL-1β in Check

    Article • Cell Host & Microbe, March 2016, Elsevier

    Si Ming Man

  20. AIM2 inflammasome in infection, cancer, and autoimmunity: Role in DNA sensing, inflammation, and innate immunity

    Article • European Journal of Immunology, December 2015, Wiley

    Si Ming Man

  21. Converging roles of caspases in inflammasome activation, cell death and innate immunity

    Article • Nature Reviews Immunology, December 2015, Springer Science + Business Media

    Si Ming Man

  22. Gasdermin D: the long-awaited executioner of pyroptosis

    Article • Cell Research, October 2015, Springer Science + Business Media

    Si Ming Man

  23. Is Campylobacter to esophageal adenocarcinoma as Helicobacter is to gastric adenocarcinoma?

    Article • Trends in Microbiology, August 2015, Elsevier

    Si Ming Man

  24. Critical Role for the DNA Sensor AIM2 in Stem Cell Proliferation and Cancer

    Article • Cell, July 2015, Elsevier

    Ankit Malik, Si Ming Man

  25. Global Epidemiology of Campylobacter Infection

    Article • Clinical Microbiology Reviews, June 2015, ASM Journals

    Si Ming Man

  26. A20 is a regulator of necroptosis

    Article • Nature Immunology, June 2015, Springer Science + Business Media

    Si Ming Man

  27. Regulation of inflammasome activation

    Article • Immunological Reviews, April 2015, Wiley

    Si Ming Man

  28. The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection

    Article • Nature Immunology, March 2015, Springer Science + Business Media

    Si Ming Man

  29. Concerted Activation of the AIM2 and NLRP3 Inflammasomes Orchestrates Host Protection against Aspergillus Infection

    Article • Cell Host & Microbe, March 2015, Elsevier

    Si Ming Man

  30. Campylobacter

    Article • January 2015, Elsevier

    Si Ming Man

  31. Transcriptomic and Proteomic Analyses Reveal Key Innate Immune Signatures in the Host Response to the Gastrointestinal Pathogen Campylobacter concisus

    Article • Infection and Immunity, December 2014, ASM Journals

    Si Ming Man

  32. Actin polymerization as a key innate immune effector mechanism to control Salmonella infection

    Article • Proceedings of the National Academy of Sciences, November 2014, Proceedings of the National Academy of Sciences

    Si Ming Man

  33. Role of Emerging Campylobacter Species in Inflammatory Bowel Diseases

    Article • Inflammatory Bowel Diseases, November 2014, Oxford University Press (OUP)

    Si Ming Man

  34. Cutting Edge: STING Mediates Protection against Colorectal Tumorigenesis by Governing the Magnitude of Intestinal Inflammation

    Article • The Journal of Immunology, October 2014, The American Association of Immunologists

    Dr Peter Vogel, Si Ming Man

  35. Inflammasome activation causes dual recruitment of NLRC4 and NLRP3 to the same macromolecular complex

    Article • Proceedings of the National Academy of Sciences, May 2014, Proceedings of the National Academy of Sciences

    Si Ming Man

  36. Salmonella exploits NLRP12-dependent innate immune signaling to suppress host defenses during infection

    Article • Proceedings of the National Academy of Sciences, December 2013, Proceedings of the National Academy of Sciences

    Si Ming Man

  37. Salmonella Infection Induces Recruitment of Caspase-8 to the Inflammasome To Modulate IL-1  Production

    Article • The Journal of Immunology, October 2013, The American Association of Immunologists

    Si Ming Man

  38. Functional relationship between Campylobacter concisus and the stomach ecosystem in health and disease

    Article • The ISME Journal, July 2013, Springer Science + Business Media

    Si Ming Man

  39. Bacterial infection of macrophages induces decrease in refractive index

    Article • Journal of Biophotonics, August 2012, Wiley

    Si Ming Man

  40. The clinical importance of emerging Campylobacter species

    Article • Nature Reviews Gastroenterology & Hepatology, October 2011, Springer Science + Business Media

    Si Ming Man

  41. Stats for papers let authors track impact

    Article • Nature, August 2011, Springer Science + Business Media

    Si Ming Man

  42. Correction: The role of bacteria and pattern-recognition receptors in Crohn's disease

    Article • Nature Reviews Gastroenterology & Hepatology, May 2011, Springer Science + Business Media

    Si Ming Man

  43. The role of bacteria and pattern-recognition receptors in Crohn's disease

    Article • Nature Reviews Gastroenterology & Hepatology, February 2011, Springer Science + Business Media

    Si Ming Man

  44. Host Attachment, Invasion, and Stimulation of Proinflammatory Cytokines by Campylobacter concisus and Other Non– Campylobacter jejuni Campylobacter Species

    Article • The Journal of Infectious Diseases, December 2010, Oxford University Press (OUP)

    Professor Andrew S Day, Si Ming Man

  45. Detection of Helicobacteraceae in Intestinal Biopsies of Children with Crohn’s Disease

    Article • Helicobacter, November 2010, Wiley

    Professor Andrew S Day, Si Ming Man

  46. Campylobacter concisus and other Campylobacter species in children with newly diagnosed Crohnʼs disease

    Article • Inflammatory Bowel Diseases, June 2010, Oxford University Press (OUP)

    Professor Andrew S Day, Si Ming Man

  47. The Internal Transcribed Spacer Region, a New Tool for Use in Species Differentiation and Delineation of Systematic Relationships within the Campylobacter Genus

    Article • Applied and Environmental Microbiology, March 2010, ASM Journals

    Si Ming Man

  48. The secretome of Campylobacter concisus

    Article • FEBS Journal, February 2010, Wiley

    Si Ming Man

  49. Campylobacter concisus: a New Character in the Crohn's Disease Story?

    Article • Journal of Clinical Microbiology, April 2009, ASM Journals

    Si Ming Man

  50. Detection and Isolation of Campylobacter Species Other than C. jejuni from Children with Crohn's Disease

    Article • Journal of Clinical Microbiology, December 2008, ASM Journals

    Si Ming Man

  51. Detection of Enterohepatic and Gastric Helicobacter Species in Fecal Specimens of Children with Crohn's Disease

    Article • Helicobacter, July 2008, Wiley

    Professor Andrew S Day, Si Ming Man