All Stories

  1. Genomic evolution of SARS-CoV-2 delta variants pre- and post-omicron emergence using alignment-free machine learning models

    Article • PLOS One, March 2026, PLOS

    Shankar Esaki Muthu

  2. Plasma CXCL8 and MCP-1 as surrogate plasma biomarkers of latent tuberculosis infection among household contacts–A cross-sectional study

    Article • PLOS Global Public Health, November 2023, PLOS

    Shankar Esaki Muthu

  3. Cancer Metastasis: A Therapeutic Target

    Article • Journal of Oncology, August 2019, Hindawi Publishing Corporation

    Shankar Esaki Muthu, Peramaiyan Rajendran

  4. Adhesion and invasion attributes of Burkholderia pseudomallei are dependent on airway surface liquid and glucose concentrations in lung epithelial cells

    Article • Environmental Microbiology Reports, February 2018, Wiley

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  5. Gut Microbial Changes, Interactions, and Their Implications on Human Lifecycle: An Ageing Perspective

    Article • BioMed Research International, January 2018, Hindawi Publishing Corporation

    Mr rohit Gundamaraju, Shankar Esaki Muthu

  6. Decrease of CD69 levels on TCR Vα7.2+CD4+ innate-like lymphocytes is associated with impaired cytotoxic functions in chronic hepatitis B virus-infected patients

    Article • Innate Immunity, June 2017, SAGE Publications

    Shankar Esaki Muthu

  7. Aberrant monocyte responses predict and characterize dengue virus infection in individuals with severe disease

    Article • Journal of Translational Medicine, May 2017, Springer Science + Business Media

    Shankar Esaki Muthu

  8. CD8+ T cells of chronic HCV-infected patients express multiple negative immune checkpoints following stimulation with HCV peptides

    Article • Cellular Immunology, March 2017, Elsevier

    Shankar Esaki Muthu

  9. Survival and Intra-Nuclear Trafficking of Burkholderia pseudomallei: Strategies of Evasion from Immune Surveillance?

    Article • PLoS Neglected Tropical Diseases, January 2017, PLOS

    Shankar Esaki Muthu

  10. Polymorphisms in the CD14 and TLR4 genes independently predict CD4+ T-cell recovery in HIV-infected individuals on antiretroviral therapy

    Article • AIDS, September 2016, Wolters Kluwer Health

    Shankar Esaki Muthu

  11. Genetic polymorphisms in the CD14 gene are associated with monocyte activation and carotid intima-media thickness in HIV-infected patients on antiretroviral therapy

    Article • Medicine, August 2016, Wolters Kluwer Health

    Shankar Esaki Muthu

  12. Erratum: Corrigendum: Computational Approach Towards Exploring Potential Anti-Chikungunya Activity of Selected Flavonoids

    Article • Scientific Reports, May 2016, Nature

    Shankar Esaki Muthu

  13. Computational Approach Towards Exploring Potential Anti-Chikungunya Activity of Selected Flavonoids

    Article • Scientific Reports, April 2016, Nature

    Shankar Esaki Muthu

  14. Aberrant Inflammasome Activation Characterizes Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome

    Article • The Journal of Immunology, April 2016, The American Association of Immunologists

    Shankar Esaki Muthu

  15. Experimental Persistent Infection of BALB/c Mice with Small-Colony Variants of Burkholderia pseudomallei Leads to Concurrent Upregulation of PD-1 on T Cells and Skewed Th1 and Th17 Responses

    Article • PLoS Neglected Tropical Diseases, March 2016, PLOS

    Shankar Esaki Muthu

  16. Attrition of Hepatic Damage Inflicted by Angiotensin II with α-Tocopherol and β-Carotene in Experimental Apolipoprotein E Knock-out Mice

    Article • Scientific Reports, December 2015, Nature

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  17. Polymorphisms at Locus 4p14 of Toll-Like Receptors TLR-1 and TLR-10 Confer Susceptibility to Gastric Carcinoma in Helicobacter pylori Infection

    Article • PLOS One, November 2015, PLOS

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  18. Regulation of CD8+ T-cell cytotoxicity in HIV-1 infection

    Article • Cellular Immunology, November 2015, Elsevier

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  19. Impaired NK Cell Activation and Chemotaxis toward Dendritic Cells Exposed to Complement-Opsonized HIV-1

    Article • The Journal of Immunology, July 2015, The American Association of Immunologists

    Shankar Esaki Muthu

  20. A Combination of Doxycycline and Ribavirin Alleviated Chikungunya Infection

    Article • PLOS One, May 2015, PLOS

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  21. Increased frequency of late-senescent T cells lacking CD127 in chronic hepatitis C disease

    Article • European Journal of Clinical Investigation, March 2015, Wiley

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  22. Plasma interleukin-18 levels are a biomarker of innate immune responses that predict and characterize tuberculosis-associated immune reconstitution inflammatory syndrome

    Article • AIDS, February 2015, Wolters Kluwer Health

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  23. Mechanistic insights on immunosenescence and chronic immune activation in HIV-tuberculosis co-infection

    Article • World Journal of Virology, January 2015, Baishideng Publishing Group Co., Limited (formerly WJG Press)

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  24. Role of PD-1 co-inhibitory pathway in HIV infection and potential therapeutic options

    Article • Retrovirology, January 2015, Springer Science + Business Media

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  25. Immuno-pathomechanism of liver fibrosis: targeting chemokine CCL2-mediated HIV:HCV nexus

    Article • Journal of Translational Medicine, December 2014, Springer Science + Business Media

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  26. High-fat diet- and angiotensin II-induced aneurysm concurrently elicits splenic hypertrophy

    Article • European Journal of Clinical Investigation, November 2014, Wiley

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu, perumal nagarajan

  27. Recalcitrant coagulase‐negative methicillin‐sensitive Staphylococcus aureus in an extremely low‐birth‐weight pre‐term infant with thrombocytopaenia

    Article • JMM Case Reports, September 2014, Society for General Microbiology

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  28. Inhibitory effects of a peptide-fusion protein (Latarcin–PAP1–Thanatin) against chikungunya virus

    Article • Antiviral Research, August 2014, Elsevier

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  29. Enhanced intracellular survival and epithelial cell adherence abilities of Burkholderia pseudomallei morphotypes are dependent on differential expression of virulence-associated proteins during mid-logarithmic growth phase

    Article • Journal of Proteomics, June 2014, Elsevier

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  30. Blockade of CXCR2 signalling: A potential therapeutic target for preventing neutrophil-mediated inflammatory diseases

    Article • Experimental Biology and Medicine, May 2014, SAGE Publications

    Shankar Esaki Muthu

  31. C-Phycocyanin Confers Protection against Oxalate-Mediated Oxidative Stress and Mitochondrial Dysfunctions in MDCK Cells

    Article • PLOS One, April 2014, PLOS

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  32. Molecular Characterization of Clinical Isolates of Moraxella catarrhalis by Randomly Amplified Polymorphic DNA Fingerprinting

    Article • Journal of Molecular Microbiology and Biotechnology, January 2014, Karger Publishers

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  33. Hepatitis C virus infection contributes to impregnation of markers of immune inhibition: potential preludes underlying viral latency and persistence

    Article • BMC Infectious Diseases, January 2014, Springer Science + Business Media

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  34. HIV-Mycobacterium tuberculosisco-infection: a ‘danger-couple model’ of disease pathogenesis

    Article • Pathogens and Disease, November 2013, Oxford University Press (OUP)

    Dr Maria Kahar Bador, Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  35. β-Carotene Attenuates Angiotensin II-Induced Aortic Aneurysm by Alleviating Macrophage Recruitment in Apoe−/− Mice

    Article • PLOS One, June 2013, PLOS

    perumal nagarajan, Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  36. Molecular signatures of T-cell inhibition in HIV-1 infection

    Article • Retrovirology, January 2013, Springer Science + Business Media

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  37. Upregulation of Inhibitory Molecules in T Cells is Associated with Altered Functions of Dendritic Cells by HIV-1 and Activation of the P38MAPK/STAT3 Signaling Pathways

    Article • Frontiers in Immunology, January 2013, Frontiers

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  38. Recent advances targeting innate immunity-mediated therapies against HIV-1 infection

    Article • Microbiology and Immunology, July 2012, Wiley

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  39. Lipodystrophy and adrenal insufficiency: Potential mediators of peripheral neuropathy in HIV infection?

    Article • Medical Hypotheses, March 2012, Elsevier

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  40. Targeting HIV-1 innate immune responses therapeutically

    Article • Current Opinion in HIV and AIDS, September 2011, Wolters Kluwer Health

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  41. Antibiogram Pattern of Moraxella catarrhalis Isolates in Acute Exacerbation Chronic Obstructive Pulmonary Disease

    Article • Chemotherapy, January 2011, Karger Publishers

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  42. Current Views on the Pathophysiology of GB Virus C Coinfection with HIV-1 Infection

    Article • Current Infectious Disease Reports, October 2010, Springer Science + Business Media

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  43. HIV-1 impairs in vitro priming of naïve T cells and gives rise to contact-dependent suppressor T cells

    Article • European Journal of Immunology, May 2010, Wiley

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  44. Common protozoans as an uncommon cause of respiratory ailments in HIV-associated immunodeficiency

    Article • FEMS Immunology & Medical Microbiology, November 2009, Oxford University Press (OUP)

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  45. Cold Agglutinins in HIV-Seropositive Participants and Diagnosis of Respiratory Disease Due to Mycoplasma pneumoniae

    Article • Journal of the International Association of Providers of AIDS Care (JIAPAC), June 2009, SAGE Publications

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  46. Alterations in acute-phase proteins among HIV-1 infected persons receiving generic HAART in southern India

    Article • Journal of Infection, June 2009, Elsevier

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  47. Predominance of methicillin-resistant Staphylococcus aureus among HIV positive subjects with pyrexia of unknown origin in Chennai, Southern India

    Article • Journal of Infection, April 2009, Elsevier

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  48. Does gender and nevirapine (NVP) influence abnormal liver functions in HIV disease?

    Article • Journal of Infection, March 2009, Elsevier

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  49. Can iron depletion inside macrophages serve to prolong HIV disease progression?

    Article • Bioscience Hypotheses, January 2009, Elsevier

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  50. Could adrenal insufficiency serve as a predictor of immune reconstitution inflammatory syndrome (IRIS) in HIV disease?

    Article • Bioscience Hypotheses, January 2009, Elsevier

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  51. GB virus infection: a silent anti-HIV panacea within?

    Article • Transactions of the Royal Society of Tropical Medicine and Hygiene, December 2008, Oxford University Press (OUP)

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  52. Changes in antioxidant profile among HIV-infected individuals on generic highly active antiretroviral therapy in southern India

    Article • International Journal of Infectious Diseases, November 2008, Elsevier

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  53. Alpha-fetoprotein as a tumor marker in hepatocellular carcinoma: investigations in south Indian subjects with hepatotropic virus and aflatoxin etiologies

    Article • International Journal of Infectious Diseases, November 2008, Elsevier

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  54. The prevalence of hepatitis B virus and hepatitis C virus infection among patients with chronic liver disease in South India

    Article • International Journal of Infectious Diseases, September 2008, Elsevier

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  55. Co-factors for abnormal lactate levels among persons with HIV disease at a tertiary HIV care setting in South India

    Article • Food and Chemical Toxicology, August 2008, Elsevier

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  56. Seroprevalence of hepatitis delta virus infection among subjects with underlying hepatic diseases in Chennai, southern India

    Article • Transactions of the Royal Society of Tropical Medicine and Hygiene, August 2008, Oxford University Press (OUP)

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  57. High rate of detection of high-level aminoglycoside-resistant enterococci from urinary tract specimens in South India

    Article • International Journal of Antimicrobial Agents, April 2008, Elsevier

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  58. Atypically distributed cutaneous lesions of Norwegian scabies in an HIV-positive man in South India: a case report

    Article • Journal of Medical Case Reports, March 2008, Springer Science + Business Media

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  59. Urinary Infections due to Multi-Drug-Resistant Escherichia coli among Persons with HIV Disease at a Tertiary AIDS Care Centre in South India

    Article • Nephron Clinical Practice, January 2008, Karger Publishers

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  60. Does CD4+CD25+foxp3+ cell (Treg) and IL-10 profile determine susceptibility to immune reconstitution inflammatory syndrome (IRIS) in HIV disease?

    Article • Journal of Inflammation, January 2008, Springer Science + Business Media

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  61. Comparative Efficacy of Two Dosages of Recombinant Hepatitis B Vaccine in Healthy Adolescents in India

    Article • The Pediatric Infectious Disease Journal, November 2007, Wolters Kluwer Health

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  62. Detection of pulmonary Mycoplasma pneumoniae infections in HIV-infected subjects using culture and serology

    Article • International Journal of Infectious Diseases, May 2007, Elsevier

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  63. Immune reconstitution inflammatory syndrome in association with HIV/AIDS and tuberculosis: Views over hidden possibilities

    Article • AIDS Research and Therapy, January 2007, Springer Science + Business Media

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  64. Prevalence of Campylobacter jejuni and enteric bacterial pathogens among hospitalized HIV infected versus non-HIV infected patients with diarrhoea in southern India

    Article • Scandinavian Journal of Infectious Diseases, January 2007, Taylor & Francis

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  65. Serosurveillance of acute Mycoplasma pneumoniae infection among HIV infected patients with pulmonary complaints in Chennai, Southern India

    Article • Journal of Infection, November 2006, Elsevier

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  66. Phenotypes of Isolates of Pseudomonas aeruginosa in a Diabetes Care Center

    Article • Archives of Medical Research, January 2006, Elsevier

    Dr Shankar Esaki Muthu, Shankar Esaki Muthu

  67. Pneumonia and Pleural Effusion due toCryptococcus Laurentiiin a Clinically Proven Case of AIDS

    Article • Canadian Respiratory Journal, January 2006, Hindawi Publishing Corporation

    Shankar Esaki Muthu