All Stories

  1. In silico approaches for investigating the binding propensity of apigenin and luteolin against class I HDAC isoforms

    Article • Future Medicinal Chemistry, July 2018, Future Science

    Dr shabir ahmad ganai, Dr Shabir Ahmad Ganai

  2. Designing Isoform-selective Inhibitors Against Classical HDACs for Effective Anticancer Therapy: Insight and Perspectives from In Silico

    Article • Current Drug Targets, April 2018, Bentham Science Publishers

    Dr shabir ahmad ganai, Dr Shabir Ahmad Ganai

  3. Histone Deacetylase Inhibitors Modulating Non-epigenetic Players: The Novel Mechanism for Small Molecule Based Therapeutic Intervention

    Article • Current Drug Targets, April 2018, Bentham Science Publishers

    Dr shabir ahmad ganai, Dr Shabir Ahmad Ganai

  4. Nuclear Lamin–Chromatin Interactions and Their Signaling Cascades

    Article • January 2018, Springer Science + Business Media

    Dr Shabir Ahmad Ganai

  5. In Silico Approaches Towards Safe Targeting of Class I Histone Deacetylases

    Article • January 2018, Springer Science + Business Media

    Dr Shabir Ahmad Ganai

  6. HDAC Inhibitors Entinostat and Suberoylanilide Hydroxamic Acid (SAHA): The Ray of Hope for Cancer Therapy

    Article • January 2018, Springer Science + Business Media

    Dr Shabir Ahmad Ganai

  7. Small-molecule Modulation of HDAC6 Activity: The Propitious Therapeutic Strategy to Vanquish Neurodegenerative Disorders

    Article • Current Medicinal Chemistry, December 2017, Bentham Science Publishers

    Dr shabir ahmad ganai, Dr Shabir Ahmad Ganai

  8. Editorial: Epigenetics: A Novel Frontier For Drug Discovery

    Article • Current Medicinal Chemistry, December 2017, Bentham Science Publishers

    Dr Shabir Ahmad Ganai

  9. Combinatorial In Silico Strategy towards Identifying Potential Hotspots during Inhibition of Structurally Identical HDAC1 and HDAC2 Enzymes for Effective Chemotherapy against Neurological Disorders

    Article • Frontiers in Molecular Neuroscience, November 2017, Frontiers

    Dr Shabir Ahmad Ganai

  10. Plant Derived Inhibitor Sulforaphane in Combinatorial Therapy Against Therapeutically Challenging Pancreatic Cancer

    Article • Anti-Cancer Agents in Medicinal Chemistry, February 2017, Bentham Science Publishers

    Dr Shabir Ahmad Ganai

  11. Plant-derived flavone Apigenin: The small-molecule with promising activity against therapeutically resistant prostate cancer

    Article • Biomedicine & Pharmacotherapy, January 2017, Elsevier

    Dr Shabir Ahmad Ganai

  12. Modulating epigenetic HAT activity for reinstating acetylation homeostasis: A promising therapeutic strategy for neurological disorders

    Article • Pharmacology & Therapeutics, October 2016, Elsevier

    Dr Shabir Ahmad Ganai

  13. In silicoandIn vitroevaluation of the anti-inflammatory potential ofCentratherum punctatumCass-A

    Article • Journal of Biomolecular Structure and Dynamics, July 2016, Taylor & Francis

    Dr Shabir Ahmad Ganai

  14. Histone deacetylase inhibitor sulforaphane: The phytochemical with vibrant activity against prostate cancer

    Article • Biomedicine & Pharmacotherapy, July 2016, Elsevier

    Dr Shabir Ahmad Ganai

  15. Novel Approaches Towards Designing of Isoform-Selective Inhibitors Against Class II Histone Deacetylases: The Acute Requirement for Targetted Anticancer Therapy

    Article • Current Topics in Medicinal Chemistry, June 2016, Bentham Science Publishers

    Dr shabir ahmad ganai, Dr Shabir Ahmad Ganai

  16. Histone deacetylase inhibitor givinostat: the small-molecule with promising activity against therapeutically challenging haematological malignancies

    Article • Journal of Chemotherapy, April 2016, Taylor & Francis

    Dr Shabir Ahmad Ganai

  17. Histone deacetylase inhibitor pracinostat in doublet therapy: a unique strategy to improve therapeutic efficacy and to tackle herculean cancer chemoresistance

    Article • Pharmaceutical Biology, February 2016, Taylor & Francis

    Dr Shabir Ahmad Ganai

  18. Histone Deacetylase (HDAC) Inhibitors - emerging roles in neuronal memory, learning, synaptic plasticity and neural regeneration

    Article • Current Neuropharmacology, January 2016, Bentham Science Publishers

    Dr Shabir Ahmad Ganai

  19. Strategy for enhancing the therapeutic efficacy of histone deacetylase inhibitor dacinostat: the novel paradigm to tackle monotonous cancer chemoresistance

    Article • Archives of Pharmacal Research, October 2015, Springer Science + Business Media

    Dr Shabir Ahmad Ganai

  20. Panobinostat: The Small Molecule Metalloenzyme Inhibitor with Marvelous Anticancer Activity

    Article • Current Topics in Medicinal Chemistry, October 2015, Bentham Science Publishers

    Dr shabir ahmad ganai, Dr Shabir Ahmad Ganai

  21. In Silico Approaches Towards Safe Targeting of Class I Histone Deacetylases

    Article • January 2015, Springer Science + Business Media

    Dr Shabir Ahmad Ganai

  22. HDAC Inhibitors Entinostat and Suberoylanilide Hydroxamic Acid (SAHA): The Ray of Hope for Cancer Therapy

    Article • January 2015, Springer Science + Business Media

    Dr Shabir Ahmad Ganai

  23. HDAC inhibition through valproic acid modulates the methylation profiles in human embryonic kidney cells

    Article • Journal of Biomolecular Structure and Dynamics, July 2014, Taylor & Francis

    Dr Shabir Ahmad Ganai

  24. Energy-optimised pharmacophore approach to identify potential hotspots during inhibition of Class II HDAC isoforms

    Article • Journal of Biomolecular Structure and Dynamics, January 2014, Taylor & Francis

    Dr Shabir Ahmad Ganai