All Stories

  1. Evolutionary spread of protein L-(iso)aspartylO-methyltransferases guides the discovery of distinct isoaspartate-containing peptides, pimtides

    Article • May 2023, Cold Spring Harbor Laboratory Press

    Seokhee Kim

  2. A dual gene-specific mutator system installs all transition mutations at similar frequencies in vivo

    Article • Nucleic Acids Research, April 2023, Oxford University Press (OUP)

    Seokhee Kim

  3. A dual gene-specific mutator system installs all transition mutations at similar rates in vivo

    Article • June 2022, Cold Spring Harbor Laboratory Press

    Seokhee Kim

  4. Bioinformatic Expansion of Borosins Uncovers Trans-Acting Peptide Backbone N-Methyltransferases in Bacteria

    Article • Biochemistry, January 2022, American Chemical Society (ACS)

    Seokhee Kim

  5. Development of a genome-targeting mutator for the adaptive evolution of microbial cells

    Article • Nucleic Acids Research, December 2021, Oxford University Press (OUP)

    Seokhee Kim

  6. Molecular mechanism underlying substrate recognition of the peptide macrocyclase PsnB

    Article • Nature Chemical Biology, September 2021, Springer Science + Business Media

    Seokhee Kim

  7. Molecular mechanism underlying substrate recognition of the peptide macrocyclase PsnB

    Article • March 2021, Cold Spring Harbor Laboratory Press

    Seokhee Kim

  8. Gene-specific mutagenesis enables rapid continuous evolution of enzymesin vivo

    Article • Nucleic Acids Research, January 2021, Oxford University Press (OUP)

    Seokhee Kim

  9. Over-activation of a nonessential bacterial protease DegP as an antibiotic strategy

    Article • Communications Biology, October 2020, Springer Science + Business Media

    Seokhee Kim

  10. Genome Mining Reveals High Topological Diversity of ω-Ester-Containing Peptides and Divergent Evolution of ATP-Grasp Macrocyclases

    Article • Journal of the American Chemical Society, January 2020, American Chemical Society (ACS)

    Seokhee Kim

  11. Introduction of Bifunctionality into the Multidomain Architecture of the ω-Ester-Containing Peptide Plesiocin

    Article • Biochemistry, October 2019, American Chemical Society (ACS)

    Seokhee Kim

  12. A Topologically Distinct Modified Peptide with Multiple Bicyclic Core Motifs Expands the Diversity of Microviridin‐Like Peptides

    Article • ChemBioChem, March 2019, Wiley

    Seokhee Kim

  13. Identification of Nucleophilic Probes for Protease-Mediated Transpeptidation

    Article • Molecules, August 2018, MDPI AG

    Seokhee Kim

  14. Tripodal Lipoprotein Variants with C-Terminal Hydrophobic Residues Allosterically Modulate Activity of the DegP Protease

    Article • Journal of Molecular Biology, October 2017, Elsevier

    Seokhee Kim

  15. A Small Periplasmic Protein with a Hydrophobic C-Terminal Residue Enhances DegP Proteolysis as a Suicide Activator

    Article • Journal of Bacteriology, September 2017, ASM Journals

    Seokhee Kim

  16. Enzymatic Cross-Linking of Side Chains Generates a Modified Peptide with Four Hairpin-like Bicyclic Repeats

    Article • Biochemistry, September 2017, American Chemical Society (ACS)

    Seokhee Kim

  17. A Conserved Activation Cluster Is Required for Allosteric Communication in HtrA-Family Proteases

    Article • Structure, March 2015, Elsevier

    Seokhee Kim

  18. Distinct regulatory mechanisms balance DegP proteolysis to maintain cellular fitness during heat stress

    Article • Genes & Development, April 2014, Cold Spring Harbor Laboratory Press

    Seokhee Kim

  19. Cage assembly of DegP protease is not required for substrate-dependent regulation of proteolytic activity or high-temperature cell survival

    Article • Proceedings of the National Academy of Sciences, April 2012, Proceedings of the National Academy of Sciences

    Seokhee Kim

  20. Covalent Linkage of Distinct Substrate Degrons Controls Assembly and Disassembly of DegP Proteolytic Cages

    Article • Cell, April 2011, Elsevier

    Seokhee Kim

  21. Reconstitution of Outer Membrane Protein Assembly from Purified Components

    Article • Science, May 2010, American Association for the Advancement of Science

    Seokhee Kim

  22. Structure and Function of an Essential Component of the Outer Membrane Protein Assembly Machine

    Article • Science, August 2007, American Association for the Advancement of Science

    Seokhee Kim

  23. YfiO stabilizes the YaeT complex and is essential for outer membrane protein assembly inEscherichia coli

    Article • Molecular Microbiology, May 2006, Wiley

    Seokhee Kim

  24. Identification of a Multicomponent Complex Required for Outer Membrane Biogenesis in Escherichia coli

    Article • Cell, April 2005, Elsevier

    Seokhee Kim