All Stories

  1. Outstanding Reviewers for ChemComm in 2023

    Article • Chemical Communications, January 2024, Royal Society of Chemistry

    Dr Seok Ki Choi

  2. Oxime-Conjugated Dendrimers as Therapeutics for Organophosphate Poisoning

    Article • University of Michigan Undergraduate Research Journal, March 2023, University of Michigan Library

    Dr Seok Ki Choi

  3. Caged Oxime Reactivators Designed for the Light Control of Acetylcholinesterase Reactivation †

    Article • Photochemistry and Photobiology, October 2021, Wiley

    Dr Seok Ki Choi

  4. Nanomaterial-Enabled Sensors and Therapeutic Platforms for Reactive Organophosphates

    Article • Nanomaterials, January 2021, MDPI AG

    Dr Seok Ki Choi

  5. Dual acting oximes designed for therapeutic decontamination of reactive organophosphates via catalytic inactivation and acetylcholinesterase reactivation

    Article • RSC Medicinal Chemistry, January 2021, Royal Society of Chemistry

    Dr Seok Ki Choi

  6. Activation Strategies in Image-Guided Nanotherapeutic Delivery

    Article • Journal of Nanotheranostics, November 2020, MDPI AG

    Dr Seok Ki Choi

  7. Dendrimer nanoreactors as emerging nanotherapeutics for treating reactive organophosphate exposure

    Article • October 2020, American Chemical Society (ACS)

    Dr Seok Ki Choi

  8. Photoactivation Strategies for Therapeutic Release in Nanodelivery Systems

    Article • Advanced Therapeutics, July 2020, Wiley

    Dr Seok Ki Choi

  9. Shielded α-Nucleophile Nanoreactor for Topical Decontamination of Reactive Organophosphate

    Article • ACS Applied Materials & Interfaces, July 2020, American Chemical Society (ACS)

    Dr Seok Ki Choi

  10. Multifunctional therapeutic strategy of Ag-synergized dual-modality upconversion nanoparticles to achieve the rapid and sustained cidality of methicillin-resistant Staphylococcus aureus

    Article • Chemical Engineering Journal, April 2020, Elsevier

    Dr Seok Ki Choi

  11. Spacer-Mediated Control of Coumarin Uncaging for Photocaged Thymidine

    Article • The Journal of Organic Chemistry, February 2020, American Chemical Society (ACS)

    Dr Seok Ki Choi

  12. Photonanotechnology for Therapeutics and Imaging

    Article • January 2020, Elsevier

    Dr Seok Ki Choi

  13. Photocleavable linkers

    Article • January 2020, Elsevier

    Dr Seok Ki Choi

  14. Front Matter

    Article • January 2020, Elsevier

    Dr Seok Ki Choi

  15. Photocontrolled nanosystems for antibacterial drug delivery

    Article • January 2020, Elsevier

    Dr Seok Ki Choi

  16. Light sources for photonanotechnology

    Article • January 2020, Elsevier

    Dr Seok Ki Choi

  17. Photocontrolled nanosystems for antitumor drug delivery

    Article • January 2020, Elsevier

    Dr Seok Ki Choi

  18. Upconversion nanocrystals for near-infrared-controlled drug delivery

    Article • January 2020, Elsevier

    Dr Seok Ki Choi

  19. Contributors

    Article • January 2020, Elsevier

    Dr Seok Ki Choi

  20. Preface

    Article • January 2020, Elsevier

    Dr Seok Ki Choi

  21. Hydrophilic scaffolds of oxime as the potent catalytic inactivator of reactive organophosphate

    Article • Chemico-Biological Interactions, January 2019, Elsevier

    Dr Seok Ki Choi

  22. Reactivity and mechanism of α-nucleophile scaffolds as catalytic organophosphate scavengers

    Article • Organic & Biomolecular Chemistry, January 2019, Royal Society of Chemistry

    Dr Seok Ki Choi

  23. Discovery of TD-0212, an Orally Active Dual Pharmacology AT1 Antagonist and Neprilysin Inhibitor (ARNI)

    Article • ACS Medicinal Chemistry Letters, December 2018, American Chemical Society (ACS)

    Dr Seok Ki Choi

  24. Measuring the Adhesion Forces for the Multivalent Binding of Vancomycin-Conjugated Dendrimer to Bacterial Cell-Wall Peptide

    Article • Langmuir, June 2018, American Chemical Society (ACS)

    Dr Seok Ki Choi

  25. Oritavancin Retains a High Affinity for a Vancomycin-Resistant Cell-Wall Precursor via Its Bivalent Motifs of Interaction

    Article • Biochemistry, April 2018, American Chemical Society (ACS)

    Dr Seok Ki Choi

  26. Lanthanide-doped core–shell nanoparticles as a multimodality platform for imaging and photodynamic therapy

    Article • Chemical Communications, January 2018, Royal Society of Chemistry

    Dr Seok Ki Choi

  27. Photocontrolled Release of Doxorubicin Conjugated through a Thioacetal Photocage in Folate-Targeted Nanodelivery Systems

    Article • Bioconjugate Chemistry, December 2017, American Chemical Society (ACS)

    Dr Seok Ki Choi

  28. Ligand Characteristics Important to Avidity Interactions of Multivalent Nanoparticles

    Article • Bioconjugate Chemistry, April 2017, American Chemical Society (ACS)

    Dr Seok Ki Choi

  29. Photodynamic Therapy: Efficacy Dependence of Photodynamic Therapy Mediated by Upconversion Nanoparticles: Subcellular Positioning and Irradiation Productivity (Small 13/2017)

    Article • Small, April 2017, Wiley

    Dr Seok Ki Choi

  30. Control of an Unusual Photo-Claisen Rearrangement in Coumarin Caged Tamoxifen through an Extended Spacer

    Article • ACS Chemical Biology, February 2017, American Chemical Society (ACS)

    Dr Seok Ki Choi

  31. Efficacy Dependence of Photodynamic Therapy Mediated by Upconversion Nanoparticles: Subcellular Positioning and Irradiation Productivity

    Article • Small, January 2017, Wiley

    Dr Seok Ki Choi

  32. Yolk-structured multifunctional up-conversion nanoparticles for synergistic photodynamic–sonodynamic antibacterial resistance therapy

    Article • Biomaterials Science, January 2017, Royal Society of Chemistry

    Dr Seok Ki Choi

  33. Riboflavin-Conjugated Multivalent Dendrimer Platform for Cancer-Targeted Drug and Gene Delivery

    Article • January 2017, Springer Science + Business Media

    Dr Seok Ki Choi

  34. Inside Cover: A Thioacetal Photocage Designed for Dual Release: Application in the Quantitation of Therapeutic Release by Synchronous Reporter Decaging (ChemBioChem 1/2017)

    Article • ChemBioChem, December 2016, Wiley

    Dr Seok Ki Choi

  35. A Thioacetal Photocage Designed for Dual Release: Application in the Quantitation of Therapeutic Release by Synchronous Reporter Decaging

    Article • ChemBioChem, November 2016, Wiley

    Dr Seok Ki Choi

  36. Mechanistic basis of light induced cytotoxicity of photoactive nanomaterials

    Article • NanoImpact, September 2016, Elsevier

    Dr Seok Ki Choi

  37. Light-controlled active release of photocaged ciprofloxacin for lipopolysaccharide-targeted drug delivery using dendrimer conjugates

    Article • Chemical Communications, January 2016, Royal Society of Chemistry

    Dr Seok Ki Choi

  38. Mechanism of Cooperativity and Nonlinear Release Kinetics in Multivalent Dendrimer–Atropine Complexes

    Article • Molecular Pharmaceutics, December 2015, American Chemical Society (ACS)

    Dr Seok Ki Choi

  39. Modular Integration of Upconverting Nanocrystal-Dendrimer Composites for Folate Receptor-Specific NIR Imaging and Light-Triggered Drug Release

    Article • Small, October 2015, Wiley

    Dr Seok Ki Choi

  40. Mechanisms of Drug Release in Nanotherapeutic Delivery Systems

    Article • Chemical Reviews, May 2015, American Chemical Society (ACS)

    Dr Seok Ki Choi

  41. Force Spectroscopy of Multivalent Binding of Riboflavin-Conjugated Dendrimers to Riboflavin Binding Protein

    Article • The Journal of Physical Chemistry B, May 2015, American Chemical Society (ACS)

    Dr Seok Ki Choi

  42. Mechanisms and Implications of Dual-Acting Methotrexate in Folate-Targeted Nanotherapeutic Delivery

    Article • International Journal of Molecular Sciences, January 2015, MDPI AG

    Dr Seok Ki Choi

  43. A lipopolysaccharide binding heteromultivalent dendrimer nanoplatform for Gram negative cell targeting

    Article • Journal of Materials Chemistry B, January 2015, Royal Society of Chemistry

    Dr Seok Ki Choi

  44. 4-Hydroxytamoxifen probes for light-dependent spatiotemporal control of Cre-ER mediated reporter gene expression

    Article • Molecular BioSystems, January 2015, Royal Society of Chemistry

    Dr Seok Ki Choi

  45. Multivalent Dendrimer Vectors with DNA Intercalation Motifs for Gene Delivery

    Article • Biomacromolecules, November 2014, American Chemical Society (ACS)

    Dr Seok Ki Choi

  46. Poly(amidoamine) Dendrimer–Methotrexate Conjugates: The Mechanism of Interaction with Folate Binding Protein

    Article • Molecular Pharmaceutics, November 2014, American Chemical Society (ACS)

    Dr Seok Ki Choi

  47. Evaluating Binding Avidities of Populations of Heterogeneous Multivalent Ligand-Functionalized Nanoparticles

    Article • ACS Nano, June 2014, American Chemical Society (ACS)

    Dr Seok Ki Choi

  48. Avidity Mechanism of Dendrimer–Folic Acid Conjugates

    Article • Molecular Pharmaceutics, May 2014, American Chemical Society (ACS)

    Dr Seok Ki Choi

  49. Atomic Force Microscopy Probing of Receptor–Nanoparticle Interactions for Riboflavin Receptor Targeted Gold–Dendrimer Nanocomposites

    Article • The Journal of Physical Chemistry B, March 2014, American Chemical Society (ACS)

    Dr Seok Ki Choi

  50. Design and mechanistic investigation of oxime-conjugated PAMAM dendrimers as the catalytic scavenger of reactive organophosphate

    Article • Journal of Materials Chemistry B, January 2014, Royal Society of Chemistry

    Dr Seok Ki Choi

  51. An AFM Force Pulling Study of Riboflavin Receptor Targeting Nanoparticles

    Article • Biophysical Journal, January 2014, Elsevier

    Dr Seok Ki Choi

  52. Avidity Modulation of Folate-Targeted Multivalent Dendrimers for Evaluating Biophysical Models of Cancer Targeting Nanoparticles

    Article • ACS Chemical Biology, September 2013, American Chemical Society (ACS)

    Dr Seok Ki Choi

  53. DNA Condensation by Partially Acetylated Poly(amido amine) Dendrimers: Effects of Dendrimer Charge Density on Complex Formation

    Article • Molecules, September 2013, MDPI AG

    Dr Seok Ki Choi

  54. Design and In vitro Validation of Multivalent Dendrimer Methotrexates as a Folate-targeting Anticancer Therapeutic

    Article • Current Pharmaceutical Design, September 2013, Bentham Science Publishers

    Dr Seok Ki Choi

  55. Paclitaxel-Conjugated PAMAM Dendrimers Adversely Affect Microtubule Structure through Two Independent Modes of Action

    Article • Biomacromolecules, March 2013, American Chemical Society (ACS)

    Professor Nils G Walter, Dr Seok Ki Choi

  56. Dendrimer-Based Multivalent Vancomycin Nanoplatform for Targeting the Drug-Resistant Bacterial Surface

    Article • ACS Nano, January 2013, American Chemical Society (ACS)

    Dr Seok Ki Choi

  57. Synthesis of a photocaged tamoxifen for light-dependent activation of Cre-ER recombinase-driven gene modification

    Article • Chemical Communications, January 2013, Royal Society of Chemistry

    Dr Seok Ki Choi

  58. An Atomic Force Microscopy Study of Riboflavin Receptor Targeting Nanoparticles

    Article • Biophysical Journal, January 2013, Elsevier

    Dr Seok Ki Choi

  59. Discovery, oral pharmacokinetics and in vivo efficacy of velusetrag, a highly selective 5-HT4 receptor agonist that has achieved proof-of-concept in patients with chronic idiopathic constipation

    Article • Bioorganic & Medicinal Chemistry Letters, October 2012, Elsevier

    Dr Seok Ki Choi

  60. Polyvalent Dendrimer-Methotrexate as a Folate Receptor-Targeted Cancer Therapeutic

    Article • Molecular Pharmaceutics, September 2012, American Chemical Society (ACS)

    Dr Seok Ki Choi

  61. Specific and Cooperative Interactions between Oximes and PAMAM Dendrimers As Demonstrated by 1 H NMR Study

    Article • The Journal of Physical Chemistry B, August 2012, American Chemical Society (ACS)

    Dr Seok Ki Choi

  62. Discovery, oral pharmacokinetics and in vivo efficacy of a highly selective 5-HT4 receptor agonist: Clinical compound TD-2749

    Article • Bioorganic & Medicinal Chemistry Letters, July 2012, Elsevier

    Dr Seok Ki Choi

  63. Effect of targeted drug delivery with G5-MTX dendrimers on induced T regulatory (iTreg) CD4+ T cells in an inflammatory bowel disease (IBD) colitis model (52.1)

    Article • The Journal of Immunology, May 2012, Oxford University Press (OUP)

    Dr Seok Ki Choi

  64. Photochemical release of methotrexate from folate receptor-targeting PAMAM dendrimer nanoconjugate

    Article • Photochemical & Photobiological Sciences, April 2012, Springer Science + Business Media

    Dr Seok Ki Choi

  65. Thermodynamic Characterization of a Riboflavin‐Dendrimer Platform for Targeted Drug Delivery Applications

    Article • The FASEB Journal, April 2012, Wiley

    Dr Seok Ki Choi

  66. Biophysical Characterization of a Riboflavin-Conjugated Dendrimer Platform for Targeted Drug Delivery

    Article • Biomacromolecules, February 2012, American Chemical Society (ACS)

    Dr Seok Ki Choi

  67. A photochemical approach for controlled drug release in targeted drug delivery

    Article • Bioorganic & Medicinal Chemistry, February 2012, Elsevier

    Dr Seok Ki Choi

  68. Taxol-Conjugated Pamam Dendrimers Utilize Three Modes of Action on Microtubule Structure

    Article • Biophysical Journal, January 2012, Elsevier

    Professor Nils G Walter, Dr Seok Ki Choi

  69. Dendrimer-based multivalent methotrexates as dual acting nanoconjugates for cancer cell targeting

    Article • European Journal of Medicinal Chemistry, January 2012, Elsevier

    Dr Seok Ki Choi

  70. A multivalent approach to the discovery of long-acting β2-adrenoceptor agonists for the treatment of asthma and COPD

    Article • Bioorganic & Medicinal Chemistry Letters, January 2012, Elsevier

    Dr Seok Ki Choi

  71. Characterizing a Riboflavin-Dendrimer Platform for Targeted Drug Delivery Applications

    Article • Biophysical Journal, January 2012, Elsevier

    Dr Seok Ki Choi

  72. Specificity and Negative Cooperativity in Dendrimer–Oxime Drug Complexation

    Article • Macromolecules, June 2011, American Chemical Society (ACS)

    Dr Seok Ki Choi

  73. Bioanalytical Screening of Riboflavin Antagonists for Targeted Drug Delivery—A Thermodynamic and Kinetic Study

    Article • ACS Medicinal Chemistry Letters, May 2011, American Chemical Society (ACS)

    Dr Seok Ki Choi

  74. Developing a Synthetic Mimic of Promoter Searching by RNA Polymerase

    Article • Biophysical Journal, February 2011, Elsevier

    Professor Nils G Walter, Dr Seok Ki Choi

  75. Characterizing Riboflavin Antagonists for Targeted Drug Delivery Applications

    Article • Biophysical Journal, February 2011, Elsevier

    Dr Seok Ki Choi

  76. Design of riboflavin-presenting PAMAM dendrimers as a new nanoplatform for cancer-targeted delivery

    Article • Bioorganic & Medicinal Chemistry Letters, September 2010, Elsevier

    Dr Seok Ki Choi

  77. Light-controlled release of caged doxorubicin from folate receptor-targeting PAMAM dendrimer nanoconjugate

    Article • Chemical Communications, January 2010, Royal Society of Chemistry

    Dr Seok Ki Choi

  78. Progress in Cancer Nanotechnology

    Article • January 2010, Elsevier

    Dr Seok Ki Choi

  79. A Multivalent Approach to the Design and Discovery of Orally Efficacious 5-HT 4 Receptor Agonists

    Article • Journal of Medicinal Chemistry, September 2009, American Chemical Society (ACS)

    Dr Seok Ki Choi

  80. Exploring the Positional Attachment of Glycopeptide/β-lactam Heterodimers

    Article • The Journal of Antibiotics, October 2008, Springer Science + Business Media

    Dr Seok Ki Choi

  81. Designing Selective, High Affinity Ligands of 5-HT 1D Receptor by Covalent Dimerization of 5-HT 1F Ligands Derived From 4-Fluoro- N -[3-(1-methyl-4-piperidinyl)-1 H -indol-5-yl]benzamide

    Article • Journal of Medicinal Chemistry, June 2008, American Chemical Society (ACS)

    Dr Seok Ki Choi

  82. Synthetic Multivalent Molecules: Concepts and Biomedical Applications. By Seok-Ki Choi.

    Article • ChemBioChem, June 2005, Wiley

    Dr Seok Ki Choi

  83. Synthetic Multivalent Molecules

    Article • April 2004, Wiley

    Dr Seok Ki Choi

  84. Appendix

    Article • April 2004, Wiley

    Dr Seok Ki Choi

  85. Frontmatter

    Article • April 2004, Wiley

    Dr Seok Ki Choi

  86. Index

    Article • April 2004, Wiley

    Dr Seok Ki Choi

  87. Introduction

    Article • April 2004, Wiley

    Dr Seok Ki Choi

  88. References

    Article • April 2004, Wiley

    Dr Seok Ki Choi

  89. Chemical Synthesis of Multivalent Molecules

    Article • April 2004, Wiley

    Dr Seok Ki Choi

  90. Multivalent Molecules Applied to Bacterial Targets

    Article • April 2004, Wiley

    Dr Seok Ki Choi

  91. Multivalent Molecules Applied to Cellular Targets

    Article • April 2004, Wiley

    Dr Seok Ki Choi

  92. Multivalent Molecules Applied to Viral Targets

    Article • April 2004, Wiley

    Dr Seok Ki Choi

  93. A structurally biased combinatorial approach for discovering new anti-picornaviral compounds

    Article • Chemistry & Biology, January 2001, Elsevier

    Dr Seok Ki Choi

  94. ChemInform Abstract: Polyvalent Interactions in Biological Systems: Implications for Design and Use of Multivalent Ligands and Inhibitors

    Article • ChemInform, March 1999, Wiley

    Dr Seok Ki Choi

  95. Polyvalent Interactions in Biological Systems: Implications for Design and Use of Multivalent Ligands and Inhibitors

    Article • Angewandte Chemie, November 1998, Wiley

    Dr Seok Ki Choi

  96. Polyvalente Wechselwirkungen in biologischen Systemen: Auswirkungen auf das Design und die Verwendung multivalenter Liganden und Inhibitoren

    Article • Angewandte Chemie, October 1998, Wiley

    Dr Seok Ki Choi

  97. Polyvalente Wechselwirkungen in biologischen Systemen: Auswirkungen auf das Design und die Verwendung multivalenter Liganden und Inhibitoren

    Article • Angewandte Chemie, October 1998, Wiley

    Dr Seok Ki Choi

  98. Optically controlled collisions of biological objects

    Article • April 1998, SPIE

    Dr Seok Ki Choi

  99. Structure-binding relation of philanthotoxins from nicotinic acetylcholine receptor binding assay

    Article • Bioorganic & Medicinal Chemistry, October 1997, Elsevier

    Dr Xuefei Huang, Dr Seok Ki Choi

  100. Generation and in Situ Evaluation of Libraries of Poly(acrylic acid) Presenting Sialosides as Side Chains as Polyvalent Inhibitors of Influenza-Mediated Hemagglutination

    Article • Journal of the American Chemical Society, May 1997, American Chemical Society (ACS)

    Dr Seok Ki Choi

  101. Optically controlled collisions of biological objects to evaluate potent polyvalent inhibitors of virus-cell adhesion

    Article • Chemistry & Biology, September 1996, Elsevier

    Dr Seok Ki Choi

  102. Monomeric inhibitors of influenza neuraminidase enhance the hemagglutination inhibition activities of polyacrylamides presenting multiple C-sialoside groups

    Article • Chemistry & Biology, February 1996, Elsevier

    Dr Seok Ki Choi

  103. Synthesis of C-5 Analogs of N -Acetylneuraminic Acid via Indium-Mediated Allylation of N-Substituted 2-Amino-2-deoxymannoses

    Article • The Journal of Organic Chemistry, January 1996, American Chemical Society (ACS)

    Dr Seok Ki Choi

  104. The action of philanthotoxin-343 and photolabile analogues on locust (Schistocerca gregaria) muscle

    Article • Invertebrate Neuroscience, September 1995, Springer Science + Business Media

    Dr Seok Ki Choi

  105. Labeling studies of photolabile philanthotoxins with nicotinic acetylcholine receptors: mode of interaction between toxin and receptor

    Article • Chemistry & Biology, January 1995, Elsevier

    Dr Seok Ki Choi

  106. Bioorganic studies of transmitter receptors with philanthotoxin analogs

    Article • Pure and Applied Chemistry, January 1994, De Gruyter

    Dr Seok Ki Choi

  107. ChemInform Abstract: Synthesis and Assay of Hybrid Analogues of Argiotoxin‐636 and Philanthotoxin‐433: Glutamate Receptor Antagonists

    Article • ChemInform, October 1993, Wiley

    Dr Seok Ki Choi

  108. Selective antagonism of native and cloned kainate and NMDA receptors by polyamine-containing toxins.

    Article • Journal of Pharmacology and Experimental Therapeutics, July 1993, Elsevier

    Dr Seok Ki Choi

  109. Synthesis and assay of hybrid analogs of argiotoxin-636 and philanthotoxin-433: glutamate receptor antagonists

    Article • Tetrahedron, June 1993, Elsevier

    Dr Seok Ki Choi

  110. ChemInform Abstract: Synthesis of Novel and Photolabile Philanthotoxin Analogs: Glutamate Receptor Antagonists

    Article • ChemInform, October 1992, Wiley

    Dr Seok Ki Choi

  111. Synthesis of novel and photolabile philanthotoxin analogs: Glutamate receptor antagonists

    Article • Tetrahedron, June 1992, Elsevier

    Dr Seok Ki Choi

  112. Philanthotoxin-433 and Analogs, Noncompetitive Antagonists of Glutamate and Nicotinic Acetylcholine Receptors

    Article • January 1992, Springer Science + Business Media

    Dr Seok Ki Choi

  113. Photocontrolled Release of Doxorubicin Conjugated through a Thioacetal Photocage in Folate-Targeted Nanodelivery Systems

    Article • American Chemical Society (ACS)

    Dr Seok Ki Choi

  114. Control of an Unusual Photo-Claisen Rearrangement in Coumarin Caged Tamoxifen through an Extended Spacer

    Article • American Chemical Society (ACS)

    Dr Seok Ki Choi