All Stories

  1. Concise synthesis of (+)-fastigiatine

    Article • Chemical Science, January 2016, Royal Society of Chemistry

    Professor Scott D Rychnovsky

  2. ChemInform Abstract: Silyl Enol Ether Prins Cyclization: Diastereoselective Formation of Substituted Tetrahydropyran-4-ones.

    Article • ChemInform, March 2015, Wiley

    Professor Scott D Rychnovsky

  3. Generation, structure and reactivity of tertiary organolithium reagents

    Article • Natural Product Reports, January 2015, Royal Society of Chemistry

    Professor Scott D Rychnovsky

  4. Synthesis of two new enrichable and MS-cleavable cross-linkers to define protein–protein interactions by mass spectrometry

    Article • Organic & Biomolecular Chemistry, January 2015, Royal Society of Chemistry

    Professor Scott D Rychnovsky

  5. Design of CID-cleavable protein cross-linkers: identical mass modifications for simpler sequence analysis

    Article • Organic & Biomolecular Chemistry, January 2015, Royal Society of Chemistry

    Professor Scott D Rychnovsky

  6. Silyl Enol Ether Prins Cyclization: Diastereoselective Formation of Substituted Tetrahydropyran-4-ones

    Article • The Journal of Organic Chemistry, September 2014, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  7. Correction to Kinetic Analysis of the HBTM-Catalyzed Esterification of an Enantiopure Secondary Alcohol

    Article • Organic Letters, August 2014, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  8. Undergraduate Laboratory Experiment To Determine Absolute Configuration Using Thin-Layer Chromatography

    Article • Journal of Chemical Education, May 2014, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  9. Discussion Addendum for: Preparation of α-Acetoxy Ethers by the Reductive Acetylation of Esters:endo-1-Bornyloxyethyl Acetate

    Article • February 2014, Wiley

    Professor Scott D Rychnovsky

  10. Developing New Isotope-Coded Mass Spectrometry-Cleavable Cross-Linkers for Elucidating Protein Structures

    Article • Analytical Chemistry, February 2014, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  11. Studies toward the Synthesis of Palhinine Lycopodium Alkaloids: A Morita–Baylis–Hillman/Intramolecular Diels–Alder Approach

    Article • Organic Letters, February 2014, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  12. ChemInform Abstract: Formation of Highly Substituted Tetrahydropyranones: Application to the Total Synthesis of Cyanolide A.

    Article • ChemInform, January 2014, Wiley

    Professor Scott D Rychnovsky

  13. Synthesis of Saturated Tetrahydropyrans

    Article • December 2013, Springer Science + Business Media

    Professor Scott D Rychnovsky

  14. Kinetic Analysis of the HBTM-Catalyzed Esterification of an Enantiopure Secondary Alcohol

    Article • Organic Letters, November 2013, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  15. Formation of Highly Substituted Tetrahydropyranones: Application to the Total Synthesis of Cyanolide A

    Article • Organic Letters, September 2013, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  16. ChemInform Abstract: Trianion Synthon Approach to Spirocyclic Heterocycles.

    Article • ChemInform, August 2013, Wiley

    Professor Scott D Rychnovsky

  17. Hedgehog Pathway Modulation by Multiple Lipid Binding Sites on the Smoothened Effector of Signal Response

    Article • Developmental Cell, August 2013, Elsevier

    Professor Scott D Rychnovsky

  18. Trianion Synthon Approach to Spirocyclic Heterocycles

    Article • Organic Letters, May 2013, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  19. Determination of Absolute Configuration of Secondary Alcohols Using Thin-Layer Chromatography

    Article • The Journal of Organic Chemistry, May 2013, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  20. Origins of Regio- and Stereochemistry in Type 2 Intramolecular N -Acylnitroso Diels–Alder Reactions: A Computational Study of Tether Length and Substituent Effects

    Article • The Journal of Organic Chemistry, April 2013, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  21. Absolute Configuration of Lactams and Oxazolidinones Using Kinetic Resolution Catalysts

    Article • Organic Letters, February 2013, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  22. Nanomole-Scale Assignment of Configuration for Primary Amines Using a Kinetic Resolution Strategy

    Article • Journal of the American Chemical Society, December 2012, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  23. Total Synthesis of Lepadiformine Alkaloids using N -Boc α-Amino Nitriles as Trianion Synthons

    Article • The Journal of Organic Chemistry, April 2012, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  24. ChemInform Abstract: DABO Boronates: Stable Heterocyclic Boronic Acid Complexes for Use in Suzuki-Miyaura Cross-Coupling Reactions.

    Article • ChemInform, January 2012, Wiley

    Professor Scott D Rychnovsky

  25. DABO Boronates: Stable Heterocyclic Boronic Acid Complexes for Use in Suzuki-Miyaura Cross-Coupling Reactions

    Article • Synlett, September 2011, Thieme Publishing Group

    Professor Scott D Rychnovsky

  26. Determination of Absolute Configuration Using Kinetic Resolution Catalysts

    Article • Organic Letters, August 2011, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  27. Total Synthesis of the Cyanolide A Aglycon

    Article • Journal of the American Chemical Society, June 2011, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  28. ChemInform Abstract: Allyl Transfer to Aldehydes and Ketones by Broensted Acid Activation of Allyl and Crotyl 1,3,2-Dioxazaborolidines.

    Article • ChemInform, February 2011, Wiley

    Professor Scott D Rychnovsky

  29. Allyl Transfer to Aldehydes and Ketones by Brønsted Acid Activation of Allyl and Crotyl 1,3,2-Dioxazaborolidines

    Article • Organic Letters, November 2010, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  30. ChemInform Abstract: Stereoselective Synthesis and the Polyene Macrolide Antibiotics

    Article • ChemInform, August 2010, Wiley

    Professor Scott D Rychnovsky

  31. ChemInform Abstract: Oxo Polyene Macrolide Antibiotics

    Article • ChemInform, August 2010, Wiley

    Professor Scott D Rychnovsky

  32. Selective enrichment and identification of azide-tagged cross-linked peptides using chemical ligation and mass spectrometry

    Article • Journal of the American Society for Mass Spectrometry, August 2010, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  33. Fully Substituted Carbon Centers by Diastereoselective Spirocyclization: Stereoselective Synthesis of (+)-Lepadiformine C

    Article • Journal of the American Chemical Society, July 2010, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  34. ChemInform Abstract: Total Synthesis of Filipin III.

    Article • ChemInform, June 2010, Wiley

    Professor Scott D Rychnovsky

  35. ChemInform Abstract: Segment-Coupling Prins Cyclizations.

    Article • ChemInform, June 2010, Wiley

    Professor Scott D Rychnovsky

  36. ChemInform Abstract: Convergent Synthesis of a Polyol Chain with 4-Acetoxy-1,3-dioxanes Using a 1,1-Bis((trimethylsilyl)methyl)ethene Linchpin.

    Article • ChemInform, June 2010, Wiley

    Professor Scott D Rychnovsky

  37. ChemInform Abstract: anti-1,3-Diols by Addition of Dialkylzinc Reagents to 4-Acetoxy-1,3-dioxanes.

    Article • ChemInform, June 2010, Wiley

    Professor Scott D Rychnovsky

  38. ChemInform Abstract: TEMPO-Catalyzed Oxidations of Alcohols Using m-CPBA: The Role of Halide Ions.

    Article • ChemInform, June 2010, Wiley

    Professor Scott D Rychnovsky

  39. ChemInform Abstract: Total Synthesis of Filipin III (I).

    Article • ChemInform, June 2010, Wiley

    Professor Scott D Rychnovsky

  40. ChemInform Abstract: Synthesis, Equilibration, and Coupling of 4-Lithio-1,3-dioxanes: Synthons for syn- and anti-1,3-Diols.

    Article • ChemInform, June 2010, Wiley

    Professor Scott D Rychnovsky

  41. ChemInform Abstract: Improved Procedure for the Reductive Acetylation of Acyclic Esters and a New Synthesis of Ethers.

    Article • ChemInform, June 2010, Wiley

    Professor Scott D Rychnovsky

  42. ChemInform Abstract: Enantioselective Reduction of Esters: Synthesis of Optically Active α-Acetoxy Ethers.

    Article • ChemInform, June 2010, Wiley

    Professor Scott D Rychnovsky

  43. ChemInform Abstract: Total Synthesis of (-)-Lycoperine A.

    Article • ChemInform, June 2010, Wiley

    Professor Scott D Rychnovsky

  44. ChemInform Abstract: Total Synthesis of Dermostatin A.

    Article • ChemInform, May 2010, Wiley

    Professor Scott D Rychnovsky

  45. ChemInform Abstract: Mukaiyama Aldol-Prins Cyclization Cascade Reaction: A Formal Total Synthesis of Leucascandrolide A.

    Article • ChemInform, May 2010, Wiley

    Professor Scott D Rychnovsky

  46. ChemInform Abstract: Stereoselectivity and Regioselectivity in the Segment-Coupling Prins Cyclization.

    Article • ChemInform, May 2010, Wiley

    Professor Scott D Rychnovsky

  47. ChemInform Abstract: β-Selective Glycosylations with Masked D-Mycosamine Precursors.

    Article • ChemInform, May 2010, Wiley

    Professor Scott D Rychnovsky

  48. ChemInform Abstract: 4-Acetoxy- and 4-Cyano-1,3-dioxanes in Synthesis

    Article • ChemInform, May 2010, Wiley

    Professor Scott D Rychnovsky

  49. ChemInform Abstract: Optically Pure α-(Trimethylsilyl)benzyl Alcohol: A Practical Chiral Auxiliary for Oxocarbenium Ion Reactions.

    Article • ChemInform, May 2010, Wiley

    Professor Scott D Rychnovsky

  50. ChemInform Abstract: Total Synthesis of the Polyene Macrolide Dermostatin A.

    Article • ChemInform, May 2010, Wiley

    Professor Scott D Rychnovsky

  51. Total Synthesis of (−)-Lycoperine A

    Article • Organic Letters, January 2010, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  52. Strict Structural Requirements for Cholesterol to Inhibit BK Channels Point to Specific Steroid-Protein Interactions

    Article • Biophysical Journal, January 2010, Elsevier

    Professor Scott D Rychnovsky

  53. Symmetric Macrocycles by a Prins Dimerization and Macrocyclization Strategy

    Article • Organic Letters, November 2009, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  54. Polyol Synthesis with β-Oxyanionic Alkyllithium Reagents: Syntheses of Aculeatins A, B, and D

    Article • Organic Letters, September 2009, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  55. ChemInform Abstract: Rhenium(VII) Catalysis of Prins Cyclization Reactions.

    Article • ChemInform, March 2009, Wiley

    Professor Scott D Rychnovsky

  56. Formal Synthesis of (-)-Kendomycin

    Article • Synfacts, March 2009, Thieme Publishing Group

    Professor Scott D Rychnovsky

  57. ChemInform Abstract: Cyclization via Carbolithiation of α-Amino Alkyllithium Reagents.

    Article • ChemInform, January 2009, Wiley

    Professor Scott D Rychnovsky

  58. Rhenium(VII) Catalysis of Prins Cyclization Reactions

    Article • Organic Letters, November 2008, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  59. Formal Synthesis of (−)-Kendomycin Featuring a Prins-Cyclization To Construct the Macrocycle

    Article • Journal of the American Chemical Society, October 2008, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  60. Cyclization via Carbolithiation of α-Amino Alkyllithium Reagents

    Article • Organic Letters, September 2008, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  61. Synthesis of ent -Cholesterol

    Article • Synfacts, August 2008, Thieme Publishing Group

    Professor Scott D Rychnovsky

  62. Assignment of Absolute Configuration to SCH 351448 via Total Synthesis †

    Article • Organic Letters, July 2008, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  63. ChemInform Abstract: Synthesis and Structural Reassignment of (+)-Epicalyxin F.

    Article • ChemInform, April 2008, Wiley

    Professor Scott D Rychnovsky

  64. A Concise Synthesis of ent -Cholesterol

    Article • The Journal of Organic Chemistry, April 2008, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  65. Synthesis of (+)-Epicalyxin F

    Article • Synfacts, April 2008, Thieme Publishing Group

    Professor Scott D Rychnovsky

  66. Lewis Acid Promoted Mukaiyama Aldol-Prins (MAP) Cyclizations of Acetals, Ketals, α-Acetoxy Ethers, and Orthoformates

    Article • Synlett, February 2008, Thieme Publishing Group

    Professor Scott D Rychnovsky

  67. Corrigendum to “Multidrug resistance protein 1 is not associated to detergent-resistant membranes” [Biochem. Biophys. Res. Commun. 355 (2007) 1025–1030]

    Article • Biochemical and Biophysical Research Communications, February 2008, Elsevier

    Professor Scott D Rychnovsky

  68. With Brønsted Acid Catalysis

    Article • January 2008, Thieme Publishing Group

    Professor Scott D Rychnovsky

  69. Hydrogenation

    Article • January 2008, Thieme Publishing Group

    Professor Scott D Rychnovsky

  70. Substrate Chirality and Specificity of Diacylglycerol Kinases and the Multisubstrate Lipid Kinase †

    Article • Biochemistry, December 2007, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  71. Total Synthesis of Leucascandrolide A (I): A New Application of the Mukaiyama Aldol—Prins Reaction.

    Article • ChemInform, November 2007, Wiley

    Professor Scott D Rychnovsky

  72. Synthesis and Structural Reassignment of (+)-Epicalyxin F

    Article • Organic Letters, November 2007, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  73. Synthesis of the C1−C52 Fragment of Amphidinol 3, Featuring a β-Alkoxy Alkyllithium Addition Reaction

    Article • Organic Letters, November 2007, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  74. A Reductive Cyclization Approach to Attenol A (I).

    Article • ChemInform, August 2007, Wiley

    Professor Scott D Rychnovsky

  75. Synthesis of Attenol B

    Article • Synfacts, August 2007, Thieme Publishing Group

    Professor Scott D Rychnovsky

  76. Total Synthesis of Leucascandrolide A:  A New Application of the Mukaiyama Aldol−Prins Reaction

    Article • The Journal of Organic Chemistry, July 2007, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  77. Multidrug resistance protein 1 is not associated to detergent-resistant membranes

    Article • Biochemical and Biophysical Research Communications, April 2007, Elsevier

    Professor Scott D Rychnovsky

  78. A Reductive Cyclization Approach to Attenol A

    Article • The Journal of Organic Chemistry, March 2007, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  79. Diastereoselective Synthesis of the Pectenotoxin 2 Non-Anomeric AB Spiroacetal

    Article • Organic Letters, February 2007, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  80. Synthesis of the C31—C67 Fragment of Amphidinol 3.

    Article • ChemInform, January 2007, Wiley

    Professor Scott D Rychnovsky

  81. Synthesis of the C31–C67 Fragment of Amphidinol 3

    Article • Angewandte Chemie, November 2006, Wiley

    Professor Scott D Rychnovsky

  82. Synthesis of the C31–C67 Fragment of Amphidinol 3

    Article • Angewandte Chemie International Edition, November 2006, Wiley

    Professor Scott D Rychnovsky

  83. Qualitative and Quantitative Measurements of Hydrogen Bond Mediated Scalar Couplings in Acyclic 1,3-Diols

    Article • Organic Letters, November 2006, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  84. Rapid Stereocontrolled Assembly of the Fully Substituted C-Aryl Glycoside of Kendomycin with a Prins Cyclization: A Formal Synthesis.

    Article • ChemInform, October 2006, Wiley

    Professor Scott D Rychnovsky

  85. Racemization in Prins Cyclization Reactions

    Article • Journal of the American Chemical Society, October 2006, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  86. Total Synthesis and Structure Assignment of (+)-Hexacyclinol

    Article • Angewandte Chemie, September 2006, Wiley

    Professor Scott D Rychnovsky

  87. Total Synthesis and Structure Assignment of (+)-Hexacyclinol

    Article • Angewandte Chemie International Edition, September 2006, Wiley

    Professor Scott D Rychnovsky

  88. Predicting NMR Spectra by Computational Methods: Structure Revision of Hexacyclinol

    Article • Organic Letters, June 2006, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  89. Solvolysis of a Tetrahydropyranyl Mesylate: Mechanistic Implications for the Prins Cyclization, 2-Oxonia-Cope Rearrangement, and Grob Fragmentation

    Article • Organic Letters, May 2006, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  90. Synthesis and Structure Revision of Calyxin Natural Products

    Article • The Journal of Organic Chemistry, April 2006, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  91. Tetrahydropyran Rings from a Mukaiyama—Michael Cascade Reaction.

    Article • ChemInform, March 2006, Wiley

    Professor Scott D Rychnovsky

  92. Stereoselectivity of Intramolecular S N ‘ Cyclizations of Alkyllithium Reagents on Methoxy Alkenes

    Article • The Journal of Organic Chemistry, February 2006, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  93. Strategies for the Generation of Molecularly Imprinted Polymeric Nitroxide Catalysts.

    Article • ChemInform, January 2006, Wiley

    Professor Scott D Rychnovsky

  94. Rapid stereocontrolled assembly of the fully substituted C-aryl glycoside of kendomycin with a Prins cyclization: a formal synthesis

    Article • Chemical Communications, January 2006, Royal Society of Chemistry

    Professor Scott D Rychnovsky

  95. Direct Assignment of the Relative Configuration in Acyclic 1,3-Diols by 1 H NMR Spectroscopy

    Article • Organic Letters, December 2005, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  96. Tetrahydropyran Rings from a Mukaiyama−Michael Cascade Reaction

    Article • Journal of the American Chemical Society, November 2005, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  97. C2-Symmetric nitroxides and their potential as enantioselective oxidants

    Article • Tetrahedron Asymmetry, October 2005, Elsevier

    Professor Scott D Rychnovsky

  98. Strategies for the Generation of Molecularly Imprinted Polymeric Nitroxide Catalysts

    Article • Organic Letters, October 2005, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  99. Reductive Spiroannulation of Nitriles with Secondary Electrophiles.

    Article • ChemInform, September 2005, Wiley

    Professor Scott D Rychnovsky

  100. Role of chirality in peptide-induced formation of cholesterol-rich domains

    Article • Biochemical Journal, September 2005, Portland Press Ltd.

    Professor Scott D Rychnovsky

  101. Synthesis of the C3−C19 Segment of Phorboxazole B

    Article • Organic Letters, July 2005, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  102. Utilization of an Oxonia-Cope Rearrangement as a Mechanistic Probe for Prins Cyclizations

    Article • Journal of the American Chemical Society, July 2005, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  103. Reductive Spiroannulation of Nitriles with Secondary Electrophiles

    Article • Organic Letters, May 2005, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  104. Oxonia-Cope Prins Cyclizations: A Facile Method for the Synthesis of Tetrahydropyranones Bearing Quaternary Centers.

    Article • ChemInform, April 2005, Wiley

    Professor Scott D Rychnovsky

  105. Enantioselective Synthesis of the C18−C25 Segment of Lasonolide A by an Oxonia-Cope Prins Cascade

    Article • Organic Letters, April 2005, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  106. A C -Glycosidation Approach to the Central Core of Amphidinol 3: Synthesis of the C39−C52 Fragment

    Article • Organic Letters, April 2005, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  107. Synthesis of the Spirofungin B Core by a Reductive Cyclization Strategy

    Article • Organic Letters, April 2005, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  108. Stereochemical course of the reductive spiroannulations of N-Boc and N-benzyl 2-cyanopiperidines

    Article • Tetrahedron, March 2005, Elsevier

    Professor Scott D Rychnovsky

  109. Application of Hemithio Ketene Acetals to the Synthesis of Spirocyclic Orthoesters.

    Article • ChemInform, January 2005, Wiley

    Professor Scott D Rychnovsky

  110. Rational Synthesis of Contra-Thermodynamic Spiroacetals by Reductive Cyclizations

    Article • Journal of the American Chemical Society, January 2005, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  111. Axial-Selective Prins Cyclizations by Solvolysis of α-Bromo Ethers.

    Article • ChemInform, December 2004, Wiley

    Professor Scott D Rychnovsky

  112. Oxonia-Cope Prins Cyclizations:  A Facile Method for the Synthesis of Tetrahydropyranones Bearing Quaternary Centers

    Article • Journal of the American Chemical Society, December 2004, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  113. Generation and Utility of Tertiary α-Aminoorganolithium Reagents.

    Article • ChemInform, November 2004, Wiley

    Professor Scott D Rychnovsky

  114. Synthesis of Rimocidinolide Methyl Ester (I), the Aglycone of (+)-Rimocidin.

    Article • ChemInform, September 2004, Wiley

    Professor Scott D Rychnovsky

  115. Application of Hemithio Ketene Acetals to the Synthesis of Spirocyclic Orthoesters

    Article • Synlett, August 2004, Thieme Publishing Group

    Professor Scott D Rychnovsky

  116. Generation and Utility of Tertiary α-Aminoorganolithium Reagents

    Article • Organic Letters, August 2004, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  117. Memory of Chirality in the Transannular Cyclization of Cyclodecenyl Radicals

    Article • Organic Letters, August 2004, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  118. Axial-Selective Prins Cyclizations by Solvolysis of α-Bromo Ethers

    Article • Journal of the American Chemical Society, August 2004, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  119. Mukaiyama Aldol—Prins Cyclizations with Ketones.

    Article • ChemInform, June 2004, Wiley

    Professor Scott D Rychnovsky

  120. Synthesis of Optically Pure Arylsilylcarbinols and Their Use as Chiral Auxiliaries in Oxacarbenium Ion Reactions.

    Article • ChemInform, May 2004, Wiley

    Professor Scott D Rychnovsky

  121. Synthesis of Rimocidinolide Methyl Ester, the Aglycone of (+)-Rimocidin

    Article • Angewandte Chemie, May 2004, Wiley

    Professor Scott D Rychnovsky

  122. Synthesis of Rimocidinolide Methyl Ester, the Aglycone of (+)-Rimocidin

    Article • Angewandte Chemie International Edition, May 2004, Wiley

    Professor Scott D Rychnovsky

  123. Intramolecular SN2′ Cyclization of an Alkyllithium Species onto a Methoxy Allyl Ether Is syn Selective.

    Article • ChemInform, May 2004, Wiley

    Professor Scott D Rychnovsky

  124. Formal Synthesis of (-)-Apicularen A.

    Article • ChemInform, January 2004, Wiley

    Professor Scott D Rychnovsky

  125. Intramolecular SN2? cyclization of an alkyllithium species onto a methoxy allyl ether is syn selectiveElectronic Supplementary Information (ESI) available: preparation and characterization of all compounds. See http://www.rsc.org/suppdata/cc/b3/b314358a/

    Article • Chemical Communications, January 2004, Royal Society of Chemistry

    Professor Scott D Rychnovsky

  126. Mukaiyama Aldol-Prins Cyclizations with Ketones

    Article • Synlett, January 2004, Thieme Publishing Group

    Professor Scott D Rychnovsky

  127. Differential modulation of the antifungal activity of amphotericin B by natural and ent-cholesterol

    Article • Bioorganic & Medicinal Chemistry Letters, January 2004, Elsevier

    Professor Scott D Rychnovsky

  128. Titanium(IV)-Promoted Mukaiyama Aldol—Prins Cyclizations.

    Article • ChemInform, December 2003, Wiley

    Professor Scott D Rychnovsky

  129. Synthesis of Optically Pure Arylsilylcarbinols and Their Use as Chiral Auxiliaries in Oxacarbenium Ion Reactions

    Article • The Journal of Organic Chemistry, December 2003, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  130. Formal Synthesis of (−)-Apicularen A

    Article • Organic Letters, September 2003, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  131. Preparation of α-Acetoxy Ethers by the Reductive Acetylation of Esters: endo-1-Bornyloxyethyl Acetate

    Article • August 2003, Wiley

    Professor Scott D Rychnovsky

  132. Titanium(IV)-Promoted Mukaiyama Aldol−Prins Cyclizations

    Article • Organic Letters, August 2003, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  133. Spiroannulation by Alkylation and Reductive Cyclization of Nitriles.

    Article • ChemInform, June 2003, Wiley

    Professor Scott D Rychnovsky

  134. Diastereoselective Additions of Nucleophiles to α-Acetoxy Ethers Using the α-(Trimethylsilyl)benzyl Auxiliary

    Article • Organic Letters, June 2003, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  135. Preparation of (R,R)-1,2:4,5-Diepoxypentane

    Article • April 2003, Wiley

    Professor Scott D Rychnovsky

  136. Synthesis of (-)-Centrolobine (I) by Prins Cyclizations that Avoid Racemization.

    Article • ChemInform, March 2003, Wiley

    Professor Scott D Rychnovsky

  137. Unified Strategy for the Synthesis of (−)-Elisapterosin B and (−)-Colombiasin A

    Article • Angewandte Chemie International Edition, March 2003, Wiley

    Professor Scott D Rychnovsky

  138. Spiroannulation by Alkylation and Reductive Cyclization of Nitriles

    Article • Angewandte Chemie International Edition, February 2003, Wiley

    Professor Scott D Rychnovsky

  139. Synthesis of (−)-Centrolobine by Prins Cyclizations that Avoid Racemization

    Article • Organic Letters, October 2002, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  140. Empirical Model for the Molar Rotations of syn -2,2-Dimethyl-1,3-dioxanes

    Article • Organic Letters, September 2002, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  141. Total synthesis of the polyene macrolide dermostatin A

    Article • Tetrahedron, August 2002, Elsevier

    Professor Scott D Rychnovsky

  142. Optically Pure α-(Trimethylsilyl)benzyl Alcohol:  A Practical Chiral Auxiliary for Oxocarbenium Ion Reactions

    Article • Organic Letters, January 2002, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  143. Role of 2-Oxonia Cope Rearrangements in Prins Cyclization Reactions

    Article • Organic Letters, November 2001, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  144. β-Selective Glycosylations with Maskedd-Mycosamine Precursors

    Article • Organic Letters, October 2001, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  145. Total Synthesis of Dermostatin A

    Article • Angewandte Chemie, September 2001, Wiley

    Professor Scott D Rychnovsky

  146. Total Synthesis of Dermostatin A

    Article • Angewandte Chemie International Edition, September 2001, Wiley

    Professor Scott D Rychnovsky

  147. Mukaiyama Aldol−Prins Cyclization Cascade Reaction:  A Formal Total Synthesis of Leucascandrolide A

    Article • Journal of the American Chemical Society, August 2001, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  148. Stereoselectivity and Regioselectivity in the Segment-Coupling Prins Cyclization

    Article • The Journal of Organic Chemistry, June 2001, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  149. Zinc/Copper Couple

    Article • April 2001, Wiley

    Professor Scott D Rychnovsky

  150. Chloroiodomethane-Zinc/Copper Couple

    Article • April 2001, Wiley

    Professor Scott D Rychnovsky

  151. Stereoselective Recognition of Monolayers of Cholesterol, ent-Cholesterol, and Epicholesterol by an Antibody

    Article • ChemBioChem, April 2001, Wiley

    Professor Scott D Rychnovsky

  152. Stereoselective Recognition of Monolayers of Cholesterol,ent-Cholesterol, and Epicholesterol by an Antibody

    Article • ChemBioChem, April 2001, Wiley

    Professor Scott D Rychnovsky

  153. Use of a Conformational Radical Clock for Evaluating Alkyllithium-Mediated Cyclization Reactions

    Article • Organic Letters, March 2001, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  154. 4-Acetoxy- and 4-Cyano-1,3-Dioxanes in Synthesis

    Article • January 2001, Springer Science + Business Media

    Professor Scott D Rychnovsky

  155. Conformational Memory in Enantioselective Radical Reductions and a New Radical Clock Reaction

    Article • Journal of the American Chemical Society, October 2000, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  156. Enantioselective reduction of esters: synthesis of optically active α-acetoxy ethers

    Article • Tetrahedron Letters, May 2000, Elsevier

    Professor Scott D Rychnovsky

  157. Synthesis of the C22−C26 Tetrahydropyran Segment of Phorboxazole by a Stereoselective Prins Cyclization

    Article • Organic Letters, May 2000, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  158. Improved Procedure for the Reductive Acetylation of Acyclic Esters and a New Synthesis of Ethers

    Article • The Journal of Organic Chemistry, January 2000, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  159. Synthesis, Equilibration, and Coupling of 4-Lithio-1,3-dioxanes:  Synthons for syn - and anti -1,3-Diols.

    Article • The Journal of Organic Chemistry, October 1999, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  160. AM1-SM2 Calculations Model the Redox Potential of Nitroxyl Radicals Such as TEMPO

    Article • The Journal of Organic Chemistry, September 1999, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  161. Synthesis, Equilibration, and Coupling of 4-Lithio-1,3-dioxanes:  Synthons for syn - and a nti -1,3-Diols

    Article • The Journal of Organic Chemistry, September 1999, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  162. Total synthesis of filipin III

    Article • Tetrahedron, July 1999, Elsevier

    Professor Scott D Rychnovsky

  163. Anti-1,3-diols by Addition of Dialkylzinc Reagents to 4-Acetoxy-1,3-dioxanes

    Article • The Journal of Organic Chemistry, March 1999, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  164. Convergent synthesis of a polyol chain with 4-acetoxy-1,3-dioxanes using a 1,1-bis((trimethylsilyl)methyl)ethene linchpin

    Article • Tetrahedron Letters, January 1999, Elsevier

    Professor Scott D Rychnovsky

  165. TEMPO-Catalyzed Oxidations of Alcohols Usingm-CPBA:  The Role of Halide Ions

    Article • The Journal of Organic Chemistry, January 1999, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  166. Segment-coupling Prins cyclizations

    Article • Tetrahedron Letters, October 1998, Elsevier

    Professor Scott D Rychnovsky

  167. Diastereoselective synthesis of polypropionates: Cationic couplings of 4-acetoxy-1,3-dioxanes with crotyl-metal reagents

    Article • Tetrahedron Letters, September 1998, Elsevier

    Professor Scott D Rychnovsky

  168. Synthesis of Chiral Nitroxides and an Unusual Racemization Reaction

    Article • The Journal of Organic Chemistry, September 1998, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  169. Nonequilibrium Radical Reductions

    Article • Journal of the American Chemical Society, June 1998, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  170. Coupling of alkynyl organometallics with 4-acetoxy-1,3-dioxanes: Synthesis of propargylic and allylic anti-1,3-diols

    Article • Tetrahedron Letters, May 1998, Elsevier

    Professor Scott D Rychnovsky

  171. Configurational Assignment of Polyene Macrolide Antibiotics Using the [13C]Acetonide Analysis

    Article • Accounts of Chemical Research, January 1998, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  172. Total Synthesis of Filipin III

    Article • Journal of the American Chemical Society, December 1997, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  173. Tandem radical nitrile transfer-cyclization reactions of 1,3-dioxane-4-nitriles: Synthesis of spirocyclic systems

    Article • Tetrahedron, December 1997, Elsevier

    Professor Scott D Rychnovsky

  174. Synthesis and biological evaluation of non-polyene analogs of amphotericin B

    Article • Bioorganic & Medicinal Chemistry Letters, December 1997, Elsevier

    Professor Scott D Rychnovsky

  175. Dialkylzinc Additions to 4-Acetoxy-1,3-dioxanes:  A Highly Stereoselective Route to Protected anti -1,3-Diols

    Article • The Journal of Organic Chemistry, September 1997, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  176. Prins Desymmetrization of a C 2 -Symmetric Diol:  Application to the Synthesis of 17-Deoxyroflamycoin

    Article • The Journal of Organic Chemistry, May 1997, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  177. Two-Dimensional NMR Analysis of Acetonide Derivatives in the Stereochemical Assignment of Polyol Chains:  The Absolute Configurations of Dermostatins A and B

    Article • The Journal of Organic Chemistry, May 1997, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  178. Approaches to the Synthesis of the Vancomycin Antibiotics. Synthesis of Orienticin C (Bis-dechlorovancomycin) Aglycon

    Article • Journal of the American Chemical Society, April 1997, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  179. Alkylation and Reductive Decyanation of 4-Cyano-2,2-dimethyl-1,3-dioxanes (Cyanohydrin Acetonides)

    Article • The Journal of Organic Chemistry, March 1997, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  180. Total Synthesis of the Polyene Macrolide Roflamycoin

    Article • Journal of the American Chemical Society, February 1997, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  181. Prins cyclization of 4-allyl-1,3-dioxanes prepared from 1,3-diol synthons. A rapid entry into functionalized tetrahydropyrans

    Article • Tetrahedron Letters, November 1996, Elsevier

    Professor Scott D Rychnovsky

  182. Iodide acceleration in the Pd-catalyzed coupling of aromatic 1,2-ditriflates with alkynes: Synthesis of enediynes

    Article • Tetrahedron Letters, October 1996, Elsevier

    Professor Scott D Rychnovsky

  183. Oxepanes from an unusual acetal cleavage of 6,8-dioxabicyclo[3.2.1]octanes

    Article • Tetrahedron Letters, January 1996, Elsevier

    Professor Scott D Rychnovsky

  184. General Synthesis of α-Acetoxy Ethers from Esters by DIBALH Reduction and Acetylation

    Article • The Journal of Organic Chemistry, January 1996, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  185. Enantioselective Oxidation of Secondary Alcohols Using a Chiral Nitroxyl ( N -Oxoammonium salt) Catalyst

    Article • The Journal of Organic Chemistry, January 1996, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  186. Filipin III:  Configuration Assignment and Confirmation by Synthetic Correlation

    Article • The Journal of Organic Chemistry, January 1996, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  187. Elucidating the Origin of Conformational Energy Differences in Substituted 1,3-Dioxanes:  A Combined Theoretical and Experimental Study

    Article • The Journal of Organic Chemistry, January 1996, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  188. Carbon−Carbon Bond Formation from Small- and Medium-Ring Lactol Acetates via Radical and Oxonium Ion Intermediates. Synthesis of (±)-Laurenan

    Article • The Journal of Organic Chemistry, January 1996, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  189. Cascade Cyclizations of Cyclic Sulfates: An Enantioselective Alternative to Polyepoxide Cyclizations in the Synthesis of Poly(tetrahydrofurans)

    Article • Journal of the American Chemical Society, December 1995, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  190. Oxo Polyene Macrolide Antibiotics

    Article • Chemical Reviews, September 1995, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  191. A Mild, Regioselective Ketal Claisen Rearrangement Promoted by Triisobutylaluminum

    Article • The Journal of Organic Chemistry, July 1995, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  192. Relative and Absolute Configuration of Filipin III

    Article • Angewandte Chemie International Edition in English, June 1995, Wiley

    Professor Scott D Rychnovsky

  193. Relative und absolute Konfiguration von Filipin III

    Article • Angewandte Chemie, June 1995, Wiley

    Professor Scott D Rychnovsky

  194. Stereoselective Radical and Cationic Couplings in 4-Acetoxy-1,3-Dioxane Rings

    Article • Synlett, June 1995, Thieme Publishing Group

    Professor Scott D Rychnovsky

  195. Stereochemical Determination of Roflamycoin: 13C Acetonide Analysis and Synthetic Correlation

    Article • Journal of the American Chemical Society, January 1995, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  196. Synthesis and revised configuration of (+)-combretastatin D-1

    Article • Tetrahedron Letters, November 1994, Elsevier

    Professor Scott D Rychnovsky

  197. Reductive lithiation of alkyl 2-thiopyridyl ethers to generate optically pure α-alkoxylithium reagents

    Article • Tetrahedron Letters, September 1994, Elsevier

    Professor Scott D Rychnovsky

  198. Synthesis of (.+-.)-Combretastatin D-1 and Combretastatin D-2

    Article • The Journal of Organic Chemistry, September 1994, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  199. Crystal and Molecular Studies of Succinimide-Lithium Salt Complexes

    Article • Chemistry of Materials, August 1994, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  200. Triphenylphosphine-Catalyzed Isomerizations of Enynes to (E,E,E)-Trienes: Phenol as a Cocatalyst

    Article • The Journal of Organic Chemistry, May 1994, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  201. Stereochemical Assignment of Roflamycoin by 13C Acetonide Analysis

    Article • Journal of the American Chemical Society, March 1994, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  202. Convergent Synthesis of the Polyene Macrolide (-)-Roxaticin

    Article • Journal of the American Chemical Society, March 1994, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  203. Rapid Construction of the Roflamycoin System

    Article • Journal of the American Chemical Society, March 1994, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  204. Chair and twist-boat conformations of 1,3-dioxanes: limitations of molecular mechanics force fields

    Article • The Journal of Organic Chemistry, September 1993, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  205. Analysis of two carbon-13 NMR correlations for determining the stereochemistry of 1,3-diol acetonides

    Article • The Journal of Organic Chemistry, June 1993, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  206. Two-directional chain synthesis: an application to the synthesis of (+)-mycoticin A

    Article • Journal of the American Chemical Society, April 1993, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  207. Convergent synthesis of the spiroacetal fragment of milbemycin β1

    Article • Journal of the Chemical Society Chemical Communications, January 1993, Royal Society of Chemistry

    Professor Scott D Rychnovsky

  208. Conformation and reactivity of anomeric radicals

    Article • Journal of the American Chemical Society, October 1992, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  209. Synthesis of the polyol chain of (-)-roxaticin.

    Article • The Journal of Organic Chemistry, August 1992, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  210. A reverse-phase HPLC assay for measuring the interaction of polyene macrolide antifungal agents with sterols

    Article • Analytical Biochemistry, August 1992, Elsevier

    Professor Scott D Rychnovsky

  211. A practical preparation of .alpha.-alkoxylithium reagents: synthesis of syn or anti 1,3-diols

    Article • The Journal of Organic Chemistry, July 1992, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  212. Synthesis of ent-cholesterol, the unnatural enantiomer

    Article • The Journal of Organic Chemistry, April 1992, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  213. An iterative and convergent synthesis of syn polyols

    Article • The Journal of Organic Chemistry, February 1992, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  214. A general approach to the asymmetric synthesis of vancomycin-related arylglycines by enolate azidation

    Article • Tetrahedron Letters, February 1992, Elsevier

    Professor Scott D Rychnovsky

  215. Enantiomeric cholesterol as a probe of ion-channel structure

    Article • Journal of the American Chemical Society, January 1992, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  216. Stereochemistry of the macrolactins

    Article • Journal of the American Chemical Society, January 1992, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  217. 1-methylcyclopropyl (MCP) ethers as protecting groups

    Article • Tetrahedron Letters, December 1991, Elsevier

    Professor Scott D Rychnovsky

  218. Regiospecificity of acetal cleavage to an enol ether using a carbon-13 labeled acetonide

    Article • Tetrahedron Letters, December 1991, Elsevier

    Professor Scott D Rychnovsky

  219. Optically pure 1,3-diols from (2R,4R)- and (2S,4S)-1,2:4,5-diepoxypentane

    Article • The Journal of Organic Chemistry, August 1991, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  220. Stereoselective synthesis of syn-1,3-diol acetonides by reductive decyanation of cyanohydrins

    Article • The Journal of Organic Chemistry, October 1990, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  221. Stereochemistry of alternating polyol chains: 13C NMR analysis of 1,3-diol acetonides

    Article • Tetrahedron Letters, January 1990, Elsevier

    Professor Scott D Rychnovsky

  222. A convergent synthesis of polyol chains

    Article • The Journal of Organic Chemistry, October 1989, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  223. Preparation of 2-lithiotetrahydropyrans: Kinetic and thermodynamic generation of alkyllithium reagents

    Article • Tetrahedron Letters, January 1989, Elsevier

    Professor Scott D Rychnovsky

  224. Iterative butenolide construction of polypropionate chains

    Article • Journal of the American Chemical Society, March 1987, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  225. Concise total synthesis of (+)-(9S)-dihydroerythronolide A

    Article • Journal of the American Chemical Society, March 1987, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  226. Free-radical cyclization of bromo acetals. Use in the construction of bicyclic acetals and lactones

    Article • Journal of the American Chemical Society, June 1983, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  227. Stereocontrolled synthesis of cis-2,5-disubstituted tetrahydrofurans and cis- and trans-linalyl oxides

    Article • Journal of the American Chemical Society, July 1981, American Chemical Society (ACS)

    Professor Scott D Rychnovsky

  228. Utilization ofα-Oxygenated Radicals in Synthesis

    Article • Wiley

    Professor Scott D Rychnovsky