All Stories

  1. Lack of the MHC class II chaperone H2-O causes susceptibility to autoimmune diseases

    Article • PLoS Biology, February 2020, PLOS

    Dr. Scheherazade Sadegh-Nasseri

  2. A step-by-step overview of the dynamic process of epitope selection by major histocompatibility complex class II for presentation to helper T cells

    Article • F1000Research, June 2016, Faculty of 1000, Ltd.

    Dr. Scheherazade Sadegh-Nasseri

  3. Exogenous antigens bind MHC class II first, and are processed by cathepsins later

    Article • Molecular Immunology, December 2015, Elsevier

    Dr. Scheherazade Sadegh-Nasseri

  4. MHC Class II Auto-Antigen Presentation is Unconventional

    Article • Frontiers in Immunology, July 2015, Frontiers

    Dr. Scheherazade Sadegh-Nasseri

  5. Determinants of immunodominance for CD4 T cells

    Article • Current Opinion in Immunology, June 2015, Elsevier

    Dr. Scheherazade Sadegh-Nasseri

  6. Divergent paths for the selection of immunodominant epitopes from distinct antigenic sources

    Article • Nature Communications, November 2014, Nature

    Dr. Scheherazade Sadegh-Nasseri

  7. HLA-DO as the Optimizer of Epitope Selection for MHC Class II Antigen Presentation

    Article • PLoS ONE, August 2013, PLOS

    Dr. Scheherazade Sadegh-Nasseri

  8. Mix to Validate: A Facile, Reversible PEGylation for Fast Screening of Potential Therapeutic Proteins In Vivo

    Article • Angewandte Chemie, June 2013, Wiley

    Dr. Scheherazade Sadegh-Nasseri

  9. Rücktitelbild: Mix to Validate: A Facile, Reversible PEGylation for Fast Screening of Potential Therapeutic Proteins In Vivo (Angew. Chem. 27/2013)

    Article • Angewandte Chemie, June 2013, Wiley

    Dr. Scheherazade Sadegh-Nasseri

  10. Back Cover: Mix to Validate: A Facile, Reversible PEGylation for Fast Screening of Potential Therapeutic Proteins In Vivo (Angew. Chem. Int. Ed. 27/2013)

    Article • Angewandte Chemie International Edition, June 2013, Wiley

    Dr. Scheherazade Sadegh-Nasseri

  11. Mix to Validate: A Facile, Reversible PEGylation for Fast Screening of Potential Therapeutic Proteins In Vivo

    Article • Angewandte Chemie International Edition, June 2013, Wiley

    Dr. Scheherazade Sadegh-Nasseri

  12. HLA-DO and Its Role in MHC Class II Antigen Presentation

    Article • Frontiers in Immunology, January 2013, Frontiers

    Dr. Scheherazade Sadegh-Nasseri

  13. Studying MHC Class II Peptide Loading and Editing In Vitro

    Article • October 2012, Springer Science + Business Media

    Dr. Scheherazade Sadegh-Nasseri

  14. Understanding how HLA-DO works

    Article • Molecular Immunology, May 2012, Elsevier

    Dr. Scheherazade Sadegh-Nasseri

  15. How HLA-DM molecules work recognition of MHC II conformational heterogeneity

    Article • January 2012, Frontiers in Bioscience

    Dr. Scheherazade Sadegh-Nasseri

  16. Resolution of infection promotes a state of dormancy and long survival of CD4 memory T cells

    Article • Immunology and Cell Biology, March 2011, Nature

    Dr. Scheherazade Sadegh-Nasseri

  17. A reductionist cell-free major histocompatibility complex class II antigen processing system identifies immunodominant epitopes

    Article • Nature Reports Stem Cells, October 2010, Nature

    Dr. Scheherazade Sadegh-Nasseri

  18. Conformational heterogeneity of MHC class II induced upon binding to different peptides is a key regulator in antigen presentation and epitope selection

    Article • Immunologic Research, January 2010, Springer Science + Business Media

    Dr. Scheherazade Sadegh-Nasseri

  19. Suboptimal engagement of the T‐cell receptor by a variety of peptide–MHC ligands triggers T‐cell anergy

    Article • Immunology, December 2009, Wiley

    Dr. Scheherazade Sadegh-Nasseri

  20. HLA-DM mediates peptide exchange by interacting transiently and repeatedly with HLA-DR1

    Article • Molecular Immunology, September 2009, Elsevier

    Dr. Scheherazade Sadegh-Nasseri

  21. Staphylococcal Enterotoxin A Induces Small Clusters of HLA-DR1 on B Cells

    Article • PLoS ONE, July 2009, PLOS

    Dr. Scheherazade Sadegh-Nasseri

  22. Anergy in Memory CD4+ T Cells Is Induced by B Cells

    Article • The Journal of Immunology, August 2008, The American Association of Immunologists

    Dr. Scheherazade Sadegh-Nasseri

  23. Short peptide sequences mimic HLA-DM functions

    Article • Molecular Immunology, April 2008, Elsevier

    Dr. Scheherazade Sadegh-Nasseri

  24. The convergent roles of tapasin and HLA-DM in antigen presentation

    Article • Trends in Immunology, March 2008, Elsevier

    Dr. Scheherazade Sadegh-Nasseri

  25. HLA-DM targets the hydrogen bond between the histidine at position β81 and peptide to dissociate HLA-DR–peptide complexes

    Article • Nature Immunology, December 2006, Nature

    Dr. Scheherazade Sadegh-Nasseri

  26. The Magnitude of TCR Engagement Is a Critical Predictor of T Cell Anergy or Activation

    Article • The Journal of Immunology, April 2004, The American Association of Immunologists

    Dr. Scheherazade Sadegh-Nasseri

  27. Synaptic PDZ Domain-mediated Protein Interactions Are Disrupted by Inhalational Anesthetics

    Article • Journal of Biological Chemistry, July 2003, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr. Scheherazade Sadegh-Nasseri

  28. Anergy in Peripheral Memory Cd4 + T Cells Induced by Low Avidity Engagement of T Cell Receptor

    Article • The Journal of Experimental Medicine, September 2001, Rockefeller University Press

    Dr. Scheherazade Sadegh-Nasseri

  29. Hla-Dm Recognizes the Flexible Conformation of Major Histocompatibility Complex Class II

    Article • The Journal of Experimental Medicine, December 2000, Rockefeller University Press

    Dr. Scheherazade Sadegh-Nasseri

  30. Determinants of the Peptide-induced Conformational Change in the Human Class II Major Histocompatibility Complex Protein HLA-DR1

    Article • Journal of Biological Chemistry, January 2000, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr. Scheherazade Sadegh-Nasseri

  31. A recombinant single-chain human class II MHC molecule (HLA-DR1) as a covalently linked heterotrimer of α chain, β chain, and antigenic peptide, with immunogenicityin vitro and reduced affinity for bacterial superantigens

    Article • European Journal of Immunology, August 1997, Wiley

    Dr. Scheherazade Sadegh-Nasseri

  32. Processing and Presentation of Endocytically Acquired Protein Antigens by MHC Class II and Class I Molecules

    Article • Immunological Reviews, June 1996, Wiley

    Dr. Scheherazade Sadegh-Nasseri

  33. Invariant chain made in Escherichia coli has an exposed N-terminal segment that blocks antigen binding to HLA-DR1 and a trimeric C-terminal segment that binds empty HLA-DR1.

    Article • Proceedings of the National Academy of Sciences, November 1995, Proceedings of the National Academy of Sciences

    Dr. Scheherazade Sadegh-Nasseri

  34. Accuracy of a Structural Homology Model for a Class II Histocompatibility Protein, HLA-DR1: Comparison to the Crystal Structure

    Article • Journal of Biomolecular Structure and Dynamics, June 1995, Taylor & Francis

    Dr. Scheherazade Sadegh-Nasseri

  35. MHC class II function preserved by low-affinity peptide interactions preceding stable binding

    Article • Nature, August 1994, Nature

    Dr. Scheherazade Sadegh-Nasseri

  36. How MHC class II molecules work: peptide-dependent completion of protein folding

    Article • Immunology Today, January 1992, Elsevier

    Dr. Scheherazade Sadegh-Nasseri

  37. A role for peptide in determining MHC class II structure

    Article • Nature, September 1991, Nature

    Dr. Scheherazade Sadegh-Nasseri

  38. A kinetic intermediate in the reaction of an antigenic peptide and I–Ek

    Article • Nature, January 1989, Nature

    Dr. Scheherazade Sadegh-Nasseri

  39. Immunogenic presentation of an immunoglobulin “tolerogen” requires interleukin 2

    Article • European Journal of Immunology, March 1988, Wiley

    Dr. Scheherazade Sadegh-Nasseri

  40. The Choice of T-Cell Epitopes Utilized on a Protein Antigen Depends on Multiple Factors Distant from, as well as at the Determinant Site

    Article • Immunological Reviews, August 1987, Wiley

    Dr. Scheherazade Sadegh-Nasseri

  41. The Major Histocompatibility Complex and the T Cell Repertoire

    Article • January 1987, Springer Science + Business Media

    Dr. Scheherazade Sadegh-Nasseri

  42. The Influence of the Molecular Context of T Cell Determinants and the non-MHC Genetic Context of the H-2b Genes on the Immunogenicity of Lysozyme

    Article • January 1986, Springer Science + Business Media

    Dr. Scheherazade Sadegh-Nasseri

  43. The Molecular Context of a Determinant Influences Its Dominant Expression in a T Cell Response Hierarchy Through “Fine Processing”

    Article • January 1986, Elsevier

    Dr. Scheherazade Sadegh-Nasseri

  44. Selective reversal of H-2-linked genetic unresponsiveness to lysozymes: II. Alteration in the T helper/T suppressor balance, owing to gene(s) linked to Ir-2, leads to responsiveness in BALB.B

    Article • European Journal of Immunology, January 1986, Wiley

    Dr. Scheherazade Sadegh-Nasseri

  45. Selective reversal of H-2 linked genetic unresponsiveness to lysozymes

    Article • Immunogenetics, January 1984, Springer Science + Business Media

    Dr. Scheherazade Sadegh-Nasseri

  46. Faculty of 1000 evaluation for Whole proteomes as internal standards in quantitative proteomics.

    Article • Faculty of 1000, Ltd.

    Dr. Scheherazade Sadegh-Nasseri

  47. Faculty of 1000 evaluation for The Thermodynamic Mechanism of Peptide-MHC Class II Complex Formation Is a Determinant of Susceptibility to HLA-DM.

    Article • Faculty of 1000, Ltd.

    Dr. Scheherazade Sadegh-Nasseri