All Stories

  1. HCMV carriage in the elderly diminishes anti-viral functionality of the adaptive immune response resulting in virus replication at peripheral sites

    Article • Frontiers in Immunology, December 2022, Frontiers

    Dr Sarah E Jackson

  2. IL-10-Secreting CD8+ T Cells Specific for Human Cytomegalovirus (HCMV): Generation, Maintenance and Phenotype

    Article • Pathogens, December 2022, MDPI AG

    Dr Sarah E Jackson

  3. Antiviral activity of Cytomegalovirus-specific CD4+ T cells against lytically infected non-haemopoietic cells

    Article • December 2022, Cold Spring Harbor Laboratory Press

    Dr Sarah E Jackson

  4. Spontaneous, persistent T-cell dependent IFN-γ release in patients who progress to Long COVID

    Article • November 2022, Research Square

    Dr Sarah E Jackson

  5. Spontaneous, persistent T-cell dependent IFN-γ release in patients who progress to Long COVID

    Article • September 2022, Research Square

    Dr Sarah E Jackson

  6. Brain injury in COVID-19 is associated with dysregulated innate and adaptive immune responses

    Article • Brain, September 2022, Oxford University Press (OUP)

    Dr Sarah E Jackson

  7. SARS-CoV-2 spike N-terminal domain modulates TMPRSS2-dependent viral entry and fusogenicity

    Article • Cell Reports, August 2022, Elsevier

    Dr Sarah E Jackson

  8. Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity

    Article • Nature, February 2022, Springer Science + Business Media

    Dr Kenzo Tokunaga, Dr Sarah E Jackson

  9. SARS-CoV-2 Omicron spike mediated immune escape and tropism shift

    Article • December 2021, Cold Spring Harbor Laboratory Press

    Dr Sarah E Jackson

  10. SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion

    Article • Nature, September 2021, Springer Science + Business Media

    Dr Kenzo Tokunaga, Professor RAJU VAISHYA, Dr Sarah E Jackson

  11. Age-related immune response heterogeneity to SARS-CoV-2 vaccine BNT162b2

    Article • Nature, June 2021, Springer Science + Business Media

    Dr Sarah E Jackson

  12. A BMPR2/YY1 Signaling Axis Is Required for Human Cytomegalovirus Latency in Undifferentiated Myeloid Cells

    Article • mBio, June 2021, ASM Journals

    Dr Sarah E Jackson

  13. Microbial communities and their characteristics in cities around the world

    Article • Cell, June 2021, Elsevier

    Maria Mercedes Zambrano, Dr Sarah E Jackson

  14. Longitudinal analysis reveals that delayed bystander CD8+ T cell activation and early immune pathology distinguish severe COVID-19 from mild disease

    Article • Immunity, June 2021, Elsevier

    Dr Sarah E Jackson

  15. Single-cell multi-omics analysis of the immune response in COVID-19

    Article • Nature Reports Stem Cells, April 2021, Springer Science + Business Media

    Dr Sarah E Jackson

  16. Latent Cytomegalovirus-Driven Recruitment of Activated CD4+ T Cells Promotes Virus Reactivation

    Article • Frontiers in Immunology, April 2021, Frontiers

    Dr Sarah E Jackson

  17. Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

    Article • Nature, March 2021, Springer Science + Business Media

    Professor Nigel James Temperton, Dr Sarah E Jackson

  18. A novel therapeutic approach to reduce post-transplant patient disease from human cytomegalovirus.

    Article • Proceedings of the National Academy of Sciences, February 2021, Proceedings of the National Academy of Sciences

    Ian Groves, Dr Sarah E Jackson

  19. SARS-CoV-2 evolution during treatment of chronic infection

    Article • Nature, February 2021, Springer Science + Business Media

    Professor Nigel James Temperton, Dr Sarah E Jackson

  20. Age-related heterogeneity in immune responses to SARS-CoV-2 vaccine BNT162b2

    Article • February 2021, Cold Spring Harbor Laboratory Press

    Dr Sarah E Jackson

  21. Delayed bystander CD8 T cell activation, early immune pathology and persistent dysregulation characterise severe COVID-19

    Article • January 2021, Cold Spring Harbor Laboratory Press

    Dr Sarah E Jackson

  22. Using Primary Human Cells to Analyze Human Cytomegalovirus Biology

    Article • January 2021, Springer Science + Business Media

    Dr Sarah E Jackson

  23. Assessing Anti-HCMV Cell Mediated Immune Responses in Transplant Recipients and Healthy Controls Using a Novel Functional Assay

    Article • Frontiers in Cellular and Infection Microbiology, June 2020, Frontiers

    Dr Sarah E Jackson

  24. The CD4+ T Cell Response to Human Cytomegalovirus in Healthy and Immunocompromised People

    Article • Frontiers in Cellular and Infection Microbiology, May 2020, Frontiers

    Dr Sarah E Jackson

  25. Advances in cytomegalovirus (CMV) biology and its relationship to health, diseases, and aging

    Article • GeroScience, March 2020, Springer Science + Business Media

    Dr Sarah E Jackson

  26. An iPSC-Derived Myeloid Lineage Model of Herpes Virus Latency and Reactivation

    Article • Frontiers in Microbiology, October 2019, Frontiers

    Dr Sarah E Jackson

  27. Generation, maintenance and tissue distribution of T cell responses to human cytomegalovirus in lytic and latent infection

    Article • Medical Microbiology and Immunology, March 2019, Springer Science + Business Media

    Dr Sarah E Jackson

  28. Distinct Roles of Extracellular Domains in the Epstein-Barr Virus-Encoded BILF1 Receptor for Signaling and Major Histocompatibility Complex Class I Downregulation

    Article • mBio, January 2019, ASM Journals

    Dr Sarah E Jackson

  29. Extracellular Lactate: A Novel Measure of T Cell Proliferation

    Article • The Journal of Immunology, December 2017, The American Association of Immunologists

    Dr Sarah E Jackson

  30. Latency-Associated Expression of Human Cytomegalovirus US28 Attenuates Cell Signaling Pathways To Maintain Latent Infection

    Article • mBio, December 2017, ASM Journals

    Dr Sarah E Jackson

  31. Latent Cytomegalovirus (CMV) Infection Does Not Detrimentally Alter T Cell Responses in the Healthy Old, But Increased Latent CMV Carriage Is Related to Expanded CMV-Specific T Cells

    Article • Frontiers in Immunology, June 2017, Frontiers

    Dr Sarah E Jackson

  32. CMV immune evasion and manipulation of the immune system with aging

    Article • GeroScience, June 2017, Springer Science + Business Media

    Dr Sarah E Jackson

  33. Human Cytomegalovirus (HCMV)-Specific CD4+ T Cells Are Polyfunctional and Can Respond to HCMV-Infected Dendritic Cells In Vitro

    Article • Journal of Virology, January 2017, ASM Journals

    Dr Sarah E Jackson

  34. Transient activation of human cytomegalovirus lytic gene expression during latency allows cytotoxic T cell killing of latently infected cells

    Article • Scientific Reports, April 2016, Nature

    Dr Sarah E Jackson

  35. The Characterization of Varicella Zoster Virus–Specific T Cells in Skin and Blood during Aging

    Article • Journal of Investigative Dermatology, July 2015, Elsevier

    Dr Sarah E Jackson

  36. Latency-Associated Viral Interleukin-10 (IL-10) Encoded by Human Cytomegalovirus Modulates Cellular IL-10 and CCL8 Secretion during Latent Infection through Changes in the Cellular MicroRNA hsa-miR-92a

    Article • Journal of Virology, September 2014, ASM Journals

    Dr Sarah E Jackson

  37. Ribosome Profiling Reveals Pervasive Translation Outside of Annotated Protein-Coding Genes

    Article • Cell Reports, September 2014, Elsevier

    Dr Sarah E Jackson

  38. Diverse Specificities, Phenotypes, and Antiviral Activities of Cytomegalovirus-Specific CD8+ T Cells

    Article • Journal of Virology, July 2014, ASM Journals

    Dr Sarah E Jackson

  39. Human Cytomegalovirus Latency-Associated Proteins Elicit Immune-Suppressive IL-10 Producing CD4+ T Cells

    Article • PLoS Pathogens, October 2013, PLOS

    Dr Sarah E Jackson

  40. Investigation of the cutaneous response to recall antigen in humansin vivo

    Article • Clinical & Experimental Immunology, July 2013, Wiley

    Dr Sarah E Jackson

  41. Human cytomegalovirus immunity and immune evasion

    Article • Virus Research, May 2011, Elsevier

    Dr Sarah E Jackson

  42. Cytomegalovirus infection induces the accumulation of short-lived, multifunctional CD4+ CD45RA+ CD27− T cells: the potential involvement of interleukin-7 in this process

    Article • Immunology, January 2011, Wiley

    Dr Sarah E Jackson

  43. Different Proliferative Potential and Migratory Characteristics of Human CD4+ Regulatory T Cells That Express either CD45RA or CD45RO

    Article • The Journal of Immunology, March 2010, The American Association of Immunologists

    Dr Sarah E Jackson

  44. Cytomegalovirus Infection Reduces Telomere Length of the Circulating T Cell Pool

    Article • The Journal of Immunology, February 2010, The American Association of Immunologists

    Dr Sarah E Jackson

  45. KLRG1 signaling induces defective Akt (ser473) phosphorylation and proliferative dysfunction of highly differentiated CD8+ T cells

    Article • Blood, April 2009, American Society of Hematology

    Dr Sarah E Jackson

  46. Cytomegalovirus-Specific CD4+ T Cells in Healthy Carriers Are Continuously Driven to Replicative Exhaustion

    Article • The Journal of Immunology, December 2005, The American Association of Immunologists

    Dr Sarah E Jackson

  47. Telomere Erosion in Memory T Cells Induced by Telomerase Inhibition at the Site of Antigenic Challenge In Vivo

    Article • The Journal of Experimental Medicine, May 2004, Rockefeller University Press

    Dr Sarah E Jackson