All Stories

  1. New model integrates innate responses, PML‐NB formation, epigenetic control and reactivation from latency

    Article • EMBO Reports, July 2021, EMBO

    Sandra K Weller

  2. The Exonuclease Activity of Herpes Simplex Virus 1 UL12 Is Required for Production of Viral DNA That Can Be Packaged To Produce Infectious Virus

    Article • Journal of Virology, September 2017, ASM Journals

    Sandra K Weller

  3. ICP8 Filament Formation Is Essential for Replication Compartment Formation during Herpes Simplex Virus Infection

    Article • Journal of Virology, December 2015, ASM Journals

    Sandra K Weller

  4. The Putative Herpes Simplex Virus 1 Chaperone Protein UL32 Modulates Disulfide Bond Formation during Infection

    Article • Journal of Virology, October 2014, ASM Journals

    Sandra K Weller

  5. Recombination Promoted by DNA Viruses: Phage λ to Herpes Simplex Virus

    Article • Annual Review of Microbiology, September 2014, Annual Reviews

    Sandra K Weller

  6. Structure of the Herpes Simplex Virus 1 Genome: Manipulation of Nicks and Gaps Can Abrogate Infectivity and Alter the Cellular DNA Damage Response

    Article • Journal of Virology, June 2014, ASM Journals

    Sandra K Weller

  7. New Herpes Simplex Virus Replication Targets

    Article • April 2014, ASM Journals

    Sandra K Weller

  8. Herpes Simplex Virus DNA Replication and Genome Maturation

    Article • April 2014, ASM Journals

    Sandra K Weller

  9. HSV-1 Protein Expression Using Recombinant Baculoviruses

    Article • January 2014, Springer Science + Business Media

    Sandra K Weller

  10. Herpes Simplex Virus Type 1 Single Strand DNA Binding Protein and Helicase/Primase Complex Disable Cellular ATR Signaling

    Article • PLoS Pathogens, October 2013, PLOS

    Sandra K Weller

  11. A short commentary on the review by Weller and Kuchta: the DNA helicase–primase complex as a target for herpes virus infection

    Article • Expert Opinion on Therapeutic Targets, September 2013, Informa Healthcare

    Sandra K Weller

  12. The DNA helicase–primase complex as a target for herpes viral infection

    Article • Expert Opinion on Therapeutic Targets, August 2013, Informa Healthcare

    Sandra K Weller

  13. Efficient Herpes Simplex Virus 1 Replication Requires Cellular ATR Pathway Proteins

    Article • Journal of Virology, October 2012, ASM Journals

    Sandra K Weller

  14. The HSV-1 Exonuclease, UL12, Stimulates Recombination by a Single Strand Annealing Mechanism

    Article • PLoS Pathogens, August 2012, PLOS

    Sandra K Weller

  15. DNA Mismatch Repair Proteins Are Required for Efficient Herpes Simplex Virus 1 Replication

    Article • Journal of Virology, September 2011, ASM Journals

    Sandra K Weller

  16. Disulfide Bond Formation Contributes to Herpes Simplex Virus Capsid Stability and Retention of Pentons

    Article • Journal of Virology, June 2011, ASM Journals

    Sandra K Weller

  17. Disulfide Bond Formation in the Herpes Simplex Virus 1 UL6 Protein Is Required for Portal Ring Formation and Genome Encapsidation

    Article • Journal of Virology, May 2011, ASM Journals

    Sandra K Weller

  18. Herpes Simplex Virus Reorganizes the Cellular DNA Repair and Protein Quality Control Machinery

    Article • PLoS Pathogens, November 2010, PLOS

    Sandra K Weller

  19. Herpes Simplex Virus Type 1 Helicase-Primase: DNA Binding and Consequent Protein Oligomerization and Primase Activation

    Article • Journal of Virology, November 2010, ASM Journals

    Sandra K Weller

  20. Physical Interaction between the Herpes Simplex Virus Type 1 Exonuclease, UL12, and the DNA Double-Strand Break-Sensing MRN Complex

    Article • Journal of Virology, October 2010, ASM Journals

    Sandra K Weller

  21. ATR and ATRIP Are Recruited to Herpes Simplex Virus Type 1 Replication Compartments Even though ATR Signaling Is Disabled

    Article • Journal of Virology, September 2010, ASM Journals

    Sandra K Weller

  22. DNA Virus Replication

    Article • March 2010, Wiley

    Sandra K Weller

  23. Herpes Simplex Virus Type 1 Immediate-Early Protein ICP22 Is Required for VICE Domain Formation during Productive Viral Infection

    Article • Journal of Virology, December 2009, ASM Journals

    Sandra K Weller

  24. Virus-Induced Chaperone-Enriched (VICE) Domains Function as Nuclear Protein Quality Control Centers during HSV-1 Infection

    Article • PLoS Pathogens, October 2009, PLOS

    Sandra K Weller

  25. Herpesvirus Genome Replication

    Article • January 2009, Springer Science + Business Media

    Sandra K Weller

  26. Oligomerization of ICP4 and Rearrangement of Heat Shock Proteins May Be Important for Herpes Simplex Virus Type 1 Prereplicative Site Formation

    Article • Journal of Virology, April 2008, ASM Journals

    Sandra K Weller

  27. Direct Interaction between the N- and C-Terminal Portions of the Herpes Simplex Virus Type 1 Origin Binding Protein UL9 Implies the Formation of a Head-to-Tail Dimer

    Article • Journal of Virology, October 2007, ASM Journals

    Sandra K Weller

  28. Enhanced Phosphorylation of Transcription Factor Sp1 in Response to Herpes Simplex Virus Type 1 Infection Is Dependent on the Ataxia Telangiectasia-Mutated Protein

    Article • Journal of Virology, July 2007, ASM Journals

    Sandra K Weller

  29. A Putative Leucine Zipper within the Herpes Simplex Virus Type 1 UL6 Protein Is Required for Portal Ring Formation

    Article • Journal of Virology, June 2007, ASM Journals

    Sandra K Weller

  30. A Mutation in the Human Herpes Simplex Virus Type 1 UL52 Zinc Finger Motif Results in Defective Primase Activity but Can Recruit Viral Polymerase and Support Viral Replication Efficiently

    Article • Journal of Virology, June 2007, ASM Journals

    Sandra K Weller

  31. Herpes simplex virus eliminates host mitochondrial DNA

    Article • EMBO Reports, December 2006, EMBO

    Sandra K Weller

  32. DNA Binding Activity of the Herpes Simplex Virus Type 1 Origin Binding Protein, UL9, Can Be Modulated by Sequences in the N Terminus: Correlation between Transdominance and DNA Binding

    Article • Journal of Virology, May 2006, ASM Journals

    Sandra K Weller

  33. Herpes Simplex Virus Type 1 DNA Polymerase Requires the Mammalian Chaperone Hsp90 for Proper Localization to the Nucleus

    Article • Journal of Virology, August 2005, ASM Journals

    Sandra K Weller

  34. Mutations in the Putative Zinc-Binding Motif of UL52 Demonstrate a Complex Interdependence between the UL5 and UL52 Subunits of the Human Herpes Simplex Virus Type 1 Helicase/Primase Complex

    Article • Journal of Virology, July 2005, ASM Journals

    Sandra K Weller

  35. Herpes Simplex Virus Type 1 Single-Strand DNA Binding Protein ICP8 Enhances the Nuclease Activity of the UL12 Alkaline Nuclease by Increasing Its Processivity

    Article • Journal of Virology, July 2005, ASM Journals

    Sandra K Weller

  36. Inhibition of the Herpes Simplex Virus Type 1 DNA Polymerase Induces Hyperphosphorylation of Replication Protein A and Its Accumulation at S-Phase-Specific Sites of DNA Damage during Infection

    Article • Journal of Virology, June 2005, ASM Journals

    Sandra K Weller

  37. Catalysis of Strand Exchange by the HSV-1 UL12 and ICP8 Proteins: Potent ICP8 Recombinase Activity is Revealed upon Resection of dsDNA Substrate by Nuclease

    Article • Journal of Molecular Biology, September 2004, Elsevier

    Sandra K Weller

  38. The UL12.5 Gene Product of Herpes Simplex Virus Type 1 Exhibits Nuclease and Strand Exchange Activities but Does Not Localize to the Nucleus

    Article • Journal of Virology, May 2004, ASM Journals

    Sandra K Weller

  39. Recruitment of Cellular Recombination and Repair Proteins to Sites of Herpes Simplex Virus Type 1 DNA Replication Is Dependent on the Composition of Viral Proteins within Prereplicative Sites and Correlates with the Induction of the DNA Damage Response

    Article • Journal of Virology, May 2004, ASM Journals

    Sandra K Weller

  40. Point Mutations in Exon I of the Herpes Simplex Virus Putative Terminase Subunit, UL15, Indicate that the Most Conserved Residues Are Essential for Cleavage and Packaging

    Article • Journal of Virology, September 2003, ASM Journals

    Sandra K Weller

  41. Existence of Transdominant and Potentiating Mutants of UL9, the Herpes Simplex Virus Type 1 Origin-Binding Protein, Suggests that Levels of UL9 Protein May Be Regulated during Infection

    Article • Journal of Virology, September 2003, ASM Journals

    Sandra K Weller

  42. The Role of DNA Recombination in Herpes Simplex Virus DNA Replication

    Article • IUBMB Life, August 2003, Wiley

    Sandra K Weller

  43. The Herpes Simplex Virus Type 1 Alkaline Nuclease and Single-Stranded DNA Binding Protein Mediate Strand Exchange In Vitro

    Article • Journal of Virology, July 2003, ASM Journals

    Sandra K Weller

  44. Recruitment of Polymerase to Herpes Simplex Virus Type 1 Replication Foci in Cells Expressing Mutant Primase (UL52) Proteins

    Article • Journal of Virology, April 2003, ASM Journals

    Sandra K Weller

  45. Helicase Motif Ia Is Involved in Single-Strand DNA-Binding and Helicase Activities of the Herpes Simplex Virus Type 1 Origin-Binding Protein, UL9

    Article • Journal of Virology, February 2003, ASM Journals

    Sandra K Weller

  46. The Product of the UL12.5 Gene of Herpes Simplex Virus Type 1 Is Not Essential for Lytic Viral Growth and Is Not Specifically Associated with Capsids

    Article • Virology, July 2002, Elsevier

    Sandra K Weller

  47. The UL6 Gene Product Forms the Portal for Entry of DNA into the Herpes Simplex Virus Capsid

    Article • Journal of Virology, November 2001, ASM Journals

    Sandra K Weller

  48. Interactions of Herpes Simplex Virus Type 1 with ND10 and Recruitment of PML to Replication Compartments

    Article • Journal of Virology, March 2001, ASM Journals

    Sandra K Weller

  49. Herpes Simplex Virus DNA Cleavage and Packaging Proteins Associate with the Procapsid prior to Its Maturation

    Article • Journal of Virology, January 2001, ASM Journals

    Sandra K Weller

  50. A tale of two HSV-1 helicases: Roles of phage and animal virus helicases in DNA replication and recombination

    Article • January 2001, Elsevier

    Sandra K Weller

  51. Evidence for Controlled Incorporation of Herpes Simplex Virus Type 1 UL26 Protease into Capsids

    Article • Journal of Virology, August 2000, ASM Journals

    Sandra K Weller

  52. Isolation of Herpes Simplex Virus Procapsids from Cells Infected with a Protease-Deficient Mutant Virus

    Article • Journal of Virology, February 2000, ASM Journals

    Sandra K Weller

  53. Functional Conservations of the Alkaline Nuclease of Herpes Simplex Type 1 and Human Cytomegalovirus

    Article • Virology, September 1998, Elsevier

    Sandra K Weller, Mr Donald R O'Boyle II

  54. The Exonuclease Activity of HSV-1 UL12 Is Required forin VivoFunction

    Article • Virology, May 1998, Elsevier

    Sandra K Weller

  55. Genetic Analysis of the UL15 Gene Locus for the Putative Terminase of Herpes Simplex Virus Type 1

    Article • Virology, March 1998, Elsevier

    Sandra K Weller

  56. The Herpes Simplex Virus Type 1 UL6 Protein Is Essential for Cleavage and Packaging but Not for Genomic Inversion

    Article • Virology, December 1996, Elsevier

    Sandra K Weller

  57. Intracellular Localization of the Herpes Simplex Virus Type-1 Origin Binding Protein, UL9

    Article • Virology, October 1996, Elsevier

    Sandra K Weller

  58. Replacement of Gly815 in Helicase Motif V Alters the Single-stranded DNA-dependent ATPase Activity of the Herpes Simplex Virus Type 1Helicase-Primase

    Article • Journal of Biological Chemistry, June 1996, American Society for Biochemistry & Molecular Biology (ASBMB)

    Sandra K Weller

  59. The Herpes Simplex Virus Type 1 Transactivator ICP0 Mediates Aberrant Intracellular Localization of the Viral Helicase/Primase Complex Subunits

    Article • Virology, June 1996, Elsevier

    Sandra K Weller

  60. The Product of a 1.9-kb mRNA Which Overlaps the HSV-1 Alkaline Nuclease Gene (UL12) Cannot Relieve the Growth Defects of a Null Mutant

    Article • Virology, January 1996, Elsevier

    Sandra K Weller

  61. Phase I trial of valaciclovir, the L-valyl ester of acyclovir, in patients with advanced human immunodeficiency virus disease.

    Article • Antimicrobial Agents and Chemotherapy, July 1994, ASM Journals

    Sandra K Weller

  62. Herpes Simplex Virus 1 Alkaline Nuclease Is Required for Efficient Egress of Capsids from the Nucleus

    Article • Virology, September 1993, Elsevier

    Sandra K Weller

  63. Genetic analysis of the herpes simplex virus type 1 UL9 gene: Isolation of a lacZ insertion mutant and expression in eukaryotic cells

    Article • Virology, October 1992, Elsevier

    Sandra K Weller

  64. The Herpes Simplex Virus Type 1 Alkaline Nuclease is Not Essential for Viral DNA Synthesis: Isolation and Characterization of a lacZ Insertion Mutant

    Article • Journal of General Virology, December 1990, Society for General Microbiology

    Sandra K Weller

  65. Herpes simplex virus type 1 mutants for the origin-binding protein induce DNA amplification in the absence of viral replication

    Article • Virology, November 1990, Elsevier

    Sandra K Weller

  66. A herpes simplex virus ribonucleotide reductase deletion mutant is defective for productive acute and reactivatable latent infections of mice and for replication in mouse cells

    Article • Virology, November 1989, Elsevier

    Sandra K Weller

  67. Herpes Simplex Virus Ribonucleotide Reductase Mutants Are Hypersensitive to Acyclovir

    Article • Antimicrobial Agents and Chemotherapy, October 1989, ASM Journals

    Sandra K Weller

  68. Herpes simplex virus ribonucleotide reductase mutants are hypersensitive to acyclovir.

    Article • Antimicrobial Agents and Chemotherapy, August 1989, ASM Journals

    Sandra K Weller

  69. Herpes simplex virus 1 helicase-primase: a complex of three herpes-encoded gene products.

    Article • Proceedings of the National Academy of Sciences, April 1989, Proceedings of the National Academy of Sciences

    Sandra K Weller

  70. UL5, A protein required for HSV DNA synthesis: Genetic analysis, overexpression in Escherichia coli, and generation of polyclonal antibodies

    Article • Virology, October 1988, Elsevier

    Sandra K Weller

  71. Factor(s) present in herpes simplex virus type 1-infected cells can compensate for the loss of the large subunit of the viral ribonucleotide reductase: characterization of an ICP6 deletion mutant

    Article • Virology, September 1988, Elsevier

    Sandra K Weller

  72. Genetic and phenotypic characterization of mutants in four essential genes that map to the left half of HSV-1 UL DNA

    Article • Virology, November 1987, Elsevier

    Sandra K Weller

  73. Sequence and mapping analyses of the herpes simplex virus DNA polymerase gene predict a C-terminal substrate binding domain.

    Article • Proceedings of the National Academy of Sciences, December 1985, Proceedings of the National Academy of Sciences

    Sandra K Weller

  74. Mutations in the herpes simplex virus major DNA-binding protein gene leading to altered sensitivity to DNA polymerase inhibitors

    Article • Virology, September 1985, Elsevier

    Sandra K Weller

  75. Genetics of Herpes Simplex Virus.

    Article • Journal of Investigative Dermatology, July 1984, Elsevier

    Sandra K Weller

  76. Genetics of Herpes Simplex Virus

    Article • Journal of Investigative Dermatology, July 1984, Elsevier

    Sandra K Weller

  77. Genetic analysis of temperature-sensitive mutants of HSV-1: The combined use of complementation and physical mapping for cistron assignment

    Article • Virology, October 1983, Elsevier

    Sandra K Weller

  78. Correlation of Transient Accumulation of Linear Unintegrated Viral DNA and Transient Cell Killing by Avian Leukosis and Reticuloendotheliosis Viruses

    Article • Cold Spring Harbor Symposia on Quantitative Biology, January 1980, Cold Spring Harbor Laboratory Press

    Sandra K Weller

  79. Cleavage and Packaging of Herpes Simplex Virus 1 DNA

    Article • Springer Science + Business Media

    Sandra K Weller