All Stories

  1. Zebularine Boosts Imatinib Efficacy in Cells of Colorectal Cancer via Wnt‐Survivin‐P‐Glycoprotein Pathway

    Article • Journal of Biochemical and Molecular Toxicology, May 2026, Wiley

    prof Samia A Shouman

  2. A study of the role of androgen receptor and androgen receptor variant 7 in TNBC patients and the effect of their targeting by Enzalutamide and EPI-001 in MDA-MB-231

    Article • The Journal of Steroid Biochemistry and Molecular Biology, January 2025, Elsevier

    prof Samia A Shouman

  3. Rebound increase in microRNA levels at the end of 5-FU-based therapy in colorectal cancer patients

    Article • Scientific Reports, August 2023, Springer Science + Business Media

    prof Samia A Shouman

  4. A Study to Explore the Role of IDH1 (R132) Mutation on Imatinib Toxicity and Effect of ABCG2/OCT1 Expression on N-Desmethyl Imatinib Plasma Level in Egyptian Chronic Myeloid Leukemia Patients

    Article • Drug Research, January 2023, Thieme Publishing Group

    prof Samia A Shouman

  5. Enhanced cytotoxic effect of doxorubicin conjugated gold nanoparticles on breast cancer model

    Article • BMC Chemistry, November 2022, Springer Science + Business Media

    Dr Marwa Sharaky, prof Samia A Shouman

  6. Molecular Design, Spectroscopic, DFT, Pharmacological, and Molecular Docking Studies of Novel Ruthenium(III)–Schiff Base Complex: An Inhibitor of Progression in HepG2 Cells

    Article • International Journal of Environmental Research and Public Health, October 2022, MDPI AG

    prof Samia A Shouman, Professor Ramadan M. Ramadan

  7. A Critical Review of Chloroquine and Hydroxychloroquine as Potential Adjuvant Agents for Treating People with Cancer

    Article • Future Pharmacology, October 2022, MDPI AG

    prof Samia A Shouman

  8. Determination of the Cut-off Value for Imatinib Plasma Levels Linked to Occurrence of Bone Pain in CML Patients

    Article • Drug Design Development and Therapy, May 2022, Taylor & Francis

    prof Samia A Shouman

  9. Laser Enhanced Combinatorial Chemo-photothermal Therapy of Green Synthesis Gold Nanoparticles Loaded with 6Mercaptopurine on Breast Cancer Model

    Article • Journal of Pharmaceutical Innovation, March 2022, Springer Science + Business Media

    prof Samia A Shouman

  10. Development of Sedative Dexmedetomidine Sublingual In Situ Gels: In Vitro and In Vivo Evaluations

    Article • Pharmaceutics, January 2022, MDPI AG

    prof Samia A Shouman

  11. Modulation of Plasma 25-Hydroxyvitamin D3 Level by Imatinib Mesylate in Patients with Chronic Myelogenous Leukemia: The Role of Uptake and Efflux Transporters

    Article • Current Therapeutic Research, January 2022, Elsevier

    prof Samia A Shouman

  12. Pharmacokinetics and Pharmacodynamics of Dexmedetomidine Administered as an Adjunct to Bupivacaine for Transversus Abdominis Plane Block in Patients Undergoing Lower Abdominal Cancer Surgery

    Article • Journal of Pain Research, January 2022, Taylor & Francis

    prof Samia A Shouman

  13. Blockade of CDK7 Reverses Endocrine Therapy Resistance in Breast Cancer

    Article • International Journal of Molecular Sciences, April 2020, MDPI AG

    prof Samia A Shouman

  14. <p>Analgesic Effect of Morphine Added to Bupivacaine in Serratus Anterior Plane Block Following Modified Radical Mastectomy. Only a Local Effect? Randomized Clinical Trial</p>

    Article • Journal of Pain Research, March 2020, Taylor & Francis

    prof Samia A Shouman

  15. Suppression of macrophages- Induced inflammation via targeting RAS and PAR-4 signaling in breast cancer cell lines

    Article • Toxicology and Applied Pharmacology, December 2019, Elsevier

    prof Samia A Shouman

  16. Simvastatin Evokes An Unpredicted Antagonism For Tamoxifen In MCF-7 Breast Cancer Cells

    Article • Cancer Management and Research, November 2019, Taylor & Francis

    Mervat Omran, Amel Ibrahim, prof Samia A Shouman

  17. Anticancer effect of nor-wogonin (5, 7, 8-trihydroxyflavone) on human triple-negative breast cancer cells via downregulation of TAK1, NF-κB, and STAT3

    Article • Pharmacological Reports, April 2019, Springer Science + Business Media

    prof Samia A Shouman

  18. Evaluation of tamoxifen and simvastatin as the combination therapy for the treatment of hormonal dependent breast cancer cells

    Article • Toxicology Reports, January 2019, Elsevier

    Mervat Omran, prof Samia A Shouman

  19. Impact of Global DNA Methylation in Treatment Outcome of Colorectal Cancer Patients

    Article • Frontiers in Pharmacology, October 2018, Frontiers

    prof Samia A Shouman

  20. Targeting colorectal cancer cell metabolism through development of cisplatin and metformin nano-cubosomes

    Article • BMC Cancer, August 2018, Springer Science + Business Media

    prof Samia A Shouman

  21. Improved chemo-photothermal therapy of hepatocellular carcinoma using chitosan-coated gold nanoparticles

    Article • Journal of Photochemistry and Photobiology B Biology, May 2018, Elsevier

    prof Samia A Shouman

  22. Sodium selenite ameliorates both intestinal and extra-intestinal changes in acetic acid-induced colitis in rats

    Article • Naunyn-Schmiedeberg s Archives of Pharmacology, April 2018, Springer Science + Business Media

    prof Samia A Shouman

  23. Corrigendum: From Resistance to Sensitivity: Insights and Implications of Biphasic Modulation of Autophagy by Sunitinib

    Article • Frontiers in Pharmacology, February 2018, Frontiers

    prof Samia A Shouman

  24. Part III: Novel checkpoint kinase 2 (Chk2) inhibitors; design, synthesis and biological evaluation of pyrimidine-benzimidazole conjugates

    Article • European Journal of Medicinal Chemistry, February 2018, Elsevier

    prof Samia A Shouman

  25. Melilotus indicus extract induces apoptosis in hepatocellular carcinoma cells via a mechanism involving mitochondria-mediated pathways

    Article • Cytotechnology, January 2018, Springer Science + Business Media

    prof Samia A Shouman

  26. Anticancer potentiality of lignan rich fraction of six Flaxseed cultivars

    Article • Scientific Reports, January 2018, Springer Science + Business Media

    Prof essam abdelsattar, prof Samia A Shouman

  27. Part II: New candidates of pyrazole-benzimidazole conjugates as checkpoint kinase 2 (Chk2) inhibitors

    Article • European Journal of Medicinal Chemistry, January 2018, Elsevier

    prof Samia A Shouman

  28. From Resistance to Sensitivity: Insights and Implications of Biphasic Modulation of Autophagy by Sunitinib

    Article • Frontiers in Pharmacology, October 2017, Frontiers

    prof Samia A Shouman

  29. Anticancer Activities of New N-hetaryl-2-cyanoacetamide Derivatives Incorporating 4,5,6,7-Tetrahydrobenzo[b]thiophene Moiety

    Article • Anti-Cancer Agents in Medicinal Chemistry, July 2017, Bentham Science Publishers

    Professor samia A shouman, Magda Fikry, prof Samia A Shouman

  30. Part I: Design, synthesis and biological evaluation of novel pyrazole-benzimidazole conjugates as checkpoint kinase 2 (Chk2) inhibitors with studying their activities alone and in combination with genotoxic drugs

    Article • European Journal of Medicinal Chemistry, July 2017, Elsevier

    prof Samia A Shouman

  31. Carbonic anhydrase inhibition boosts the antitumor effects of Imatinib mesylate via potentiating the antiangiogenic and antimetastatic machineries

    Article • Toxicology and Applied Pharmacology, February 2017, Elsevier

    prof Samia A Shouman

  32. Design, Synthesis, and Cytotoxicity Evaluation of Novel Griseofulvin Analogues with Improved Water Solubility

    Article • International Journal of Medicinal Chemistry, January 2017, Hindawi Publishing Corporation

    prof Samia A Shouman

  33. Could Caffeic Acid Phenethyl Ester Expand the Antitumor Effect of Tamoxifen in Breast Carcinoma?

    Article • Nutrition and Cancer, March 2016, Taylor & Francis

    Dr eman elbaz, prof Samia A Shouman

  34. Combination of metformin and 5-aminosalicylic acid cooperates to decrease proliferation and induce apoptosis in colorectal cancer cell lines

    Article • BMC Cancer, February 2016, Springer Science + Business Media

    prof Samia A Shouman

  35. Modulation of Tamoxifen Cytotoxicity by Caffeic Acid Phenethyl Ester in MCF-7 Breast Cancer Cells

    Article • Oxidative Medicine and Cellular Longevity, January 2016, Hindawi Publishing Corporation

    Dr eman elbaz, prof Samia A Shouman

  36. Leptin influences estrogen metabolism and increases DNA adduct formation in breast cancer cells

    Article • Cancer Biology and Medicine, January 2016, Cancer Biology and Medicine

    prof Samia A Shouman

  37. The Combination ofα-Tocopheryl Succinate and Sodium Selenite on Breast Cancer: A Merit or a Demerit?

    Article • Oxidative Medicine and Cellular Longevity, January 2016, Hindawi Publishing Corporation

    prof Samia A Shouman

  38. A study to explore the correlation of ABCB1, ABCG2, OCT1 genetic polymorphisms and trough level concentration with imatinib mesylate-induced thrombocytopenia in chronic myeloid leukemia patients

    Article • Cancer Chemotherapy and Pharmacology, November 2015, Springer Science + Business Media

    prof Samia A Shouman

  39. Targeting glycolysis by 3-bromopyruvate improves tamoxifen cytotoxicity of breast cancer cell lines

    Article • BMC Cancer, November 2015, Springer Science + Business Media

    prof Samia A Shouman

  40. Dorzolamide synergizes the antitumor activity of mitomycin C against Ehrlich’s carcinoma grown in mice: role of thioredoxin-interacting protein

    Article • Naunyn-Schmiedeberg s Archives of Pharmacology, August 2015, Springer Science + Business Media

    prof Samia A Shouman

  41. Cu (I) catalyzed alkyne-azide 1,3-dipolar cycloaddition (CuAAC): Synthesis of 17α-[1-(substituted phenyl)-1,2,3-triazol-4-yl]-19-nor-testosterone-17β-yl acetates targeting progestational and antipro-liferative activities

    Article • European Journal of Medicinal Chemistry, June 2015, Elsevier

    prof Samia A Shouman

  42. A study to explore the correlation of trough level concentration and ABCB1, OCT1, ABCG2 genetic polymorphisms with imatinib mesylate induced thrombocytopenia in chronic myeloid leukemia patients.

    Article • Journal of Clinical Oncology, May 2015, American Society of Clinical Oncology (ASCO)

    prof Samia A Shouman

  43. Combination of imatinib and clotrimazole enhances cell growth inhibition in T47D breast cancer cells

    Article • Chemico-Biological Interactions, May 2015, Elsevier

    prof Samia A Shouman

  44. Chemopreventive and therapeutic potentials of thymoquinone in HepG2 cells: mechanistic perspectives

    Article • Journal of Natural Medicines, March 2015, Springer Science + Business Media

    prof Samia A Shouman

  45. Cytotoxic and Antimicrobial Evaluations of Novel Apoptotic and Anti-Angiogenic Spiro Cyclic 2-Oxindole Derivatives of 2-Amino-tetrahydroquinolin-5-one

    Article • Archiv der Pharmazie, February 2015, Wiley

    prof Samia A Shouman

  46. Effect of N-acetylcysteine on γ-radiation-induced cytotoxicity in human hepatocellular carcinoma cells

    Article • Biomedicine & Aging Pathology, October 2014, Elsevier

    prof Samia A Shouman

  47. Modulation of Imatinib Cytotoxicity by Selenite in HCT116 Colorectal Cancer Cells

    Article • Basic & Clinical Pharmacology & Toxicology, July 2014, Wiley

    Dr Abeer Mostafa Elsayed, Professor samia A shouman, prof Samia A Shouman

  48. Chloroquine synergizes sunitinib cytotoxicity via modulating autophagic, apoptotic and angiogenic machineries

    Article • Chemico-Biological Interactions, June 2014, Elsevier

    prof Samia A Shouman

  49. Modulatory effects of l-carnitine on tamoxifen toxicity and oncolytic activity

    Article • Human & Experimental Toxicology, December 2013, SAGE Publications

    prof Samia A Shouman

  50. Resveratrol inhibits proliferation, angiogenesis and induces apoptosis in colon cancer cells

    Article • Human & Experimental Toxicology, March 2013, SAGE Publications

    prof Samia A Shouman

  51. Synthesis and Biological Evaluation of a Novel Series of Chalcones Incorporated Pyrazole Moiety as Anticancer and Antimicrobial Agents

    Article • Applied Biochemistry and Biotechnology, September 2012, Springer Science + Business Media

    prof Samia A Shouman

  52. Pharmacokinetics, immunogenicity and anticancer efficiency of Aspergillus flavipes l-methioninase

    Article • Enzyme and Microbial Technology, September 2012, Elsevier

    prof Samia A Shouman

  53. Effect of Tumour Necrosis Factor-Alpha on Estrogen Metabolic Pathways in Breast Cancer Cells

    Article • Journal of Cancer, January 2012, Ivyspring International Publisher

    prof Samia A Shouman

  54. Ameliorating effect of DL-α-lipoic acid against cisplatin-induced nephrotoxicity and cardiotoxicity in experimental animals

    Article • Drug Discoveries & Therapeutics, January 2012, International Research and Cooperation Association for Bio & Socio-Sciences Advancement (IRCA-BSSA)

    prof Samia A Shouman

  55. Promising antitumor effect of alpha-tocopheryl succinate in human colon and liver cancer cells

    Article • Medicinal Chemistry Research, October 2011, Springer Science + Business Media

    prof Samia A Shouman

  56. Design, synthesis and in vitro antitumor activity of 4-aminoquinoline and 4-aminoquinazoline derivatives targeting EGFR tyrosine kinase

    Article • Bioorganic & Medicinal Chemistry, August 2008, Elsevier

    prof Samia A Shouman

  57. Modulation of radiation-induced organs toxicity by cremophor-el in experimental animals

    Article • Pharmacological Research, February 2001, Elsevier

    prof Samia A Shouman

  58. PROPIONYL- ? -CARNITINE AS POTENTIAL PROTECTIVE AGENT AGAINST ADRIAMYCIN-INDUCED IMPAIRMENT OF FATTY ACID BETA-OXIDATION IN ISOLATED HEART MITOCHONDRIA

    Article • Pharmacological Research, February 2000, Elsevier

    prof Samia A Shouman

  59. REVERSAL OF DOXORUBICIN-INDUCED CARDIAC METABOLIC DAMAGE BYL-CARNITINE

    Article • Pharmacological Research, April 1999, Elsevier

    prof Samia A Shouman

  60. Effect of Glutathione Modulation On the Distribution and Transplacental Uptake of 2-[14C]-Chloroacetonitrile (Can) Quantitative Whole-Body Autoradiographic Study in Pregnant Mice

    Article • Toxicology and Industrial Health, September 1998, SAGE Publications

    prof Samia A Shouman

  61. A STUDY ON THE REPRODUCTIVE TOXICITY OF ERYTHROSINE IN MALE MICE

    Article • Pharmacological Research, May 1997, Elsevier

    prof Samia A Shouman

  62. Urinary CA 19.9 as marker for bladder cancer

    Article • The Lancet, August 1995, Elsevier

    prof Samia A Shouman

  63. Effect of glutathione modulation on molecular interaction of [14C]-chloroacetonitrile with maternal and fetal DNA in mice

    Article • Reproductive Toxicology, May 1993, Elsevier

    prof Samia A Shouman

  64. Pulmonary toxicity of acrylonitrile: covalent interaction and effect on replicative and unscheduled DNA synthesis in the lung

    Article • Toxicology, November 1992, Elsevier

    prof Samia A Shouman