All Stories

  1. Systematic Analysis of Two-Component Systems in Citrobacter rodentium Reveals Positive and Negative Roles in Virulence

    Article • Infection and Immunity, November 2016, ASM Journals

    Dr Samantha Gruenheid

  2. ER egress of invariant chain isoform p35 requires direct binding to MHCII molecules and is inhibited by the NleA virulence factor of enterohaemorrhagic Escherichia coli

    Article • Human Immunology, April 2015, Elsevier

    Dr Samantha Gruenheid

  3. The CpxRA Two-Component System Is Essential for Citrobacter rodentium Virulence

    Article • Infection and Immunity, February 2015, ASM Journals

    Dr Samantha Gruenheid

  4. EnterohemorrhagicEscherichia coliOmpT regulates outer membrane vesicle biogenesis

    Article • FEMS Microbiology Letters, May 2014, Oxford University Press (OUP)

    Dr Samantha Gruenheid

  5. Contribution of increased ISG15, ISGylation and deregulated type I IFN signaling in Usp18 mutant mice during the course of bacterial infections

    Article • Genes & Immunity, May 2014, Springer Science + Business Media

    Dr Samantha Gruenheid

  6. Both Group 4 Capsule and Lipopolysaccharide O-Antigen Contribute to Enteropathogenic Escherichia coli Resistance to Human α-Defensin 5

    Article • PLoS ONE, December 2013, PLOS

    Dr Samantha Gruenheid

  7. The inhibition of COPII trafficking is important for intestinal epithelial tight junction disruption during enteropathogenic Escherichia coli and Citrobacter rodentium infection

    Article • Microbes and Infection, September 2013, Elsevier

    Dr Samantha Gruenheid

  8. Rspo2contrôle l’issue de l’infection parC. rodentiumchez la souris

    Article • médecine/sciences, August 2013, EDP Sciences

    Dr Samantha Gruenheid

  9. Role of uropathogenic Escherichia coli OmpT in the resistance against human cathelicidin LL-37

    Article • FEMS Microbiology Letters, June 2013, Oxford University Press (OUP)

    Dr Samantha Gruenheid

  10. R-Spondin 2 signalling mediates susceptibility to fatal infectious diarrhoea

    Article • Nature Communications, May 2013, Springer Science + Business Media

    Dr Samantha Gruenheid

  11. Identification of Potentially Diarrheagenic Atypical Enteropathogenic Escherichia coli Strains Present in Canadian Food Animals at Slaughter and in Retail Meats

    Article • Applied and Environmental Microbiology, April 2013, ASM Journals

    Dr Samantha Gruenheid

  12. Enterohemorrhagic and enteropathogenic Escherichia coli evolved different strategies to resist antimicrobial peptides

    Article • Gut Microbes, November 2012, Taylor & Francis

    Dr Samantha Gruenheid

  13. Sec24 interaction is essential for localization and virulence-associated function of the bacterial effector protein NleA

    Article • Cellular Microbiology, April 2012, Wiley

    Dr Samantha Gruenheid

  14. Resistance to antimicrobial peptides in Gram-negative bacteria

    Article • FEMS Microbiology Letters, March 2012, Oxford University Press (OUP)

    Dr Samantha Gruenheid

  15. An N-Ethyl-N-Nitrosourea (ENU)-Induced Dominant Negative Mutation in the JAK3 Kinase Protects against Cerebral Malaria

    Article • PLoS ONE, February 2012, PLOS

    Dr Samantha Gruenheid

  16. OmpT Outer Membrane Proteases of Enterohemorrhagic and Enteropathogenic Escherichia coli Contribute Differently to the Degradation of Human LL-37

    Article • Infection and Immunity, December 2011, ASM Journals

    Dr Samantha Gruenheid

  17. Perturbation of Host Cell Cytoskeleton by Cranberry Proanthocyanidins and Their Effect on Enteric Infections

    Article • PLoS ONE, November 2011, PLOS

    Dr Samantha Gruenheid

  18. The Cri1 locus is the common genetic cause of susceptibility toCitrobacter rodentiuminfection in C3H and FVB mouse strains.

    Article • Gut Microbes, May 2011, Taylor & Francis

    Dr Samantha Gruenheid

  19. Identification and characterization of Cri1, a locus controlling mortality during Citrobacter rodentium infection in mice

    Article • Genes & Immunity, February 2011, Springer Science + Business Media

    Dr Samantha Gruenheid

  20. Antibacterial autophagy occurs at PI(3)P-enriched domains of the endoplasmic reticulum and requires Rab1 GTPase

    Article • Autophagy, January 2011, Taylor & Francis

    Dr Samantha Gruenheid

  21. Forward genetic dissection of innate response to infection in inbred mouse strains: selected success stories

    Article • Clinical & Experimental Immunology, November 2010, Wiley

    Dr Samantha Gruenheid

  22. The bacterial virulence factor NleA's involvement in intestinal tight junction disruption during EnteropathogenicE. coliinfection is independent of its putative PDZ binding domain

    Article • Gut Microbes, March 2010, Taylor & Francis

    Dr Samantha Gruenheid

  23. The bacterial virulence factor NleA is required for the disruption of intestinal tight junctions by enteropathogenicEscherichia coli

    Article • Cellular Microbiology, January 2010, Wiley

    Dr Samantha Gruenheid

  24. An outer membrane protease of the omptin family prevents activation of the Citrobacter rodentium PhoPQ two-component system by antimicrobial peptides

    Article • Molecular Microbiology, October 2009, Wiley

    Dr Samantha Gruenheid

  25. Use of Nramp2-transfected Chinese hamster ovary cells and reticulocytes from mk/mk mice to study iron transport mechanisms

    Article • Experimental Hematology, October 2008, Elsevier

    Dr Samantha Gruenheid

  26. Characterization of the NleF effector protein from attaching and effacing bacterial pathogens

    Article • FEMS Microbiology Letters, April 2008, Oxford University Press (OUP)

    Dr Samantha Gruenheid

  27. Caspase-12 Modulates NOD Signaling and Regulates Antimicrobial Peptide Production and Mucosal Immunity

    Article • Cell Host & Microbe, March 2008, Elsevier

    Dr Samantha Gruenheid

  28. Molecular Analysis as an Aid To Assess the Public Health Risk of Non-O157 Shiga Toxin-Producing Escherichia coli Strains

    Article • Applied and Environmental Microbiology, February 2008, ASM Journals

    Dr Samantha Gruenheid

  29. Phosphorylated YDXV Motifs and Nck SH2/SH3 Adaptors Act Cooperatively To Induce Actin Reorganization

    Article • Molecular and Cellular Biology, January 2008, ASM Journals

    Dr Samantha Gruenheid

  30. The Bacterial Virulence Factor NleA Inhibits Cellular Protein Secretion by Disrupting Mammalian COPII Function

    Article • Cell Host & Microbe, September 2007, Elsevier

    Dr Samantha Gruenheid

  31. Regulation of Type III Secretion Hierarchy of Translocators and Effectors in Attaching and Effacing Bacterial Pathogens

    Article • Infection and Immunity, April 2005, ASM Journals

    Dr Samantha Gruenheid

  32. Modeling enteropathogenic and enterohemorrhagic E. coli infections and disease

    Article • Drug Discovery Today Disease Models, October 2004, Elsevier

    Dr Samantha Gruenheid

  33. Dissecting virulence: Systematic and functional analyses of a pathogenicity island

    Article • Proceedings of the National Academy of Sciences, February 2004, Proceedings of the National Academy of Sciences

    Dr Samantha Gruenheid

  34. Identification and characterization of NleA, a non-LEE-encoded type III translocated virulence factor of enterohaemorrhagic Escherichia coli O157:H7

    Article • Molecular Microbiology, February 2004, Wiley

    Dr Samantha Gruenheid

  35. Microbial pathogenesis and cytoskeletal function

    Article • Nature, April 2003, Springer Science + Business Media

    Dr Samantha Gruenheid

  36. Delivery of dangerous goods: Type III secretion in enteric pathogens

    Article • International Journal of Medical Microbiology, January 2002, Elsevier

    Dr Samantha Gruenheid

  37. Enteropathogenic E. coli Tir binds Nck to initiate actin pedestal formation in host cells

    Article • Nature Cell Biology, August 2001, Springer Science + Business Media

    Dr Samantha Gruenheid

  38. Gut Feelings: EnteropathogenicE. coli(EPEC) Interactions with the Host

    Article • Annual Review of Cell and Developmental Biology, November 2000, Annual Reviews

    Dr Samantha Gruenheid

  39. Crowd control: quorum sensing in pathogenic E. coli

    Article • Trends in Microbiology, October 2000, Elsevier

    Dr Samantha Gruenheid

  40. Genetic susceptibility to intracellular infections: Nramp1, macrophage function and divalent cations transport

    Article • Current Opinion in Microbiology, February 2000, Elsevier

    Dr Samantha Gruenheid

  41. The Nramp1 Protein and Its Role in Resistance to Infection and Macrophage Function

    Article • Proceedings of the Association of American Physicians, July 1999, Wiley

    Dr Samantha Gruenheid

  42. The Iron Transport Protein NRAMP2 Is an Integral Membrane Glycoprotein That Colocalizes with Transferrin in Recycling Endosomes

    Article • The Journal of Experimental Medicine, March 1999, Rockefeller University Press

    Dr Samantha Gruenheid

  43. Nramp1

    Article • January 1999, Elsevier

    Dr Samantha Gruenheid

  44. Host Resistance to Intracellular Infection: Mutation of Natural Resistance-associated Macrophage Protein 1 ( Nramp1 ) Impairs Phagosomal Acidification

    Article • The Journal of Experimental Medicine, July 1998, Rockefeller University Press

    Dr Samantha Gruenheid

  45. Functional Complementation of the Yeast Divalent Cation Transporter Family SMF by NRAMP2, a Member of the Mammalian Natural Resistance-associated Macrophage Protein Family

    Article • Journal of Biological Chemistry, November 1997, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Samantha Gruenheid

  46. Natural Resistance to Infection with Intracellular Pathogens: The Nramp1 Protein Is Recruited to the Membrane of the Phagosome

    Article • The Journal of Experimental Medicine, February 1997, Rockefeller University Press

    Dr Samantha Gruenheid

  47. Close linkage of three neuronal genes on distal mouse Chromosome 15

    Article • Mammalian Genome, September 1996, Springer Science + Business Media

    Dr Samantha Gruenheid

  48. Identification and characterization of a second mouse Nramp gene

    Article • Genomics, January 1995, Elsevier

    Dr Samantha Gruenheid

  49. Toxin resistance and reduced secretion in a mouse L-cell mutant defective in herpes virus propagation

    Article • Biochemistry and Cell Biology, October 1992, Canadian Science Publishing

    Dr Samantha Gruenheid