All Stories

  1. Beyond Bioenergetics: Moonlighting Functions of F 1 F O ‐ATPase From ATP Synthesis to an ATP‐Wasting Death Switch

    Article • Medicinal Research Reviews, July 2026, Wiley

    Salvatore Nesci

  2. Mitochondrial DNA and Mitochondrial-Derived Vesicles as Immunometabolic Modulators of Innate Immunosurveillance through Control of the Mitochondrial Permeability Transition Pore

    Article • Translational Insights, July 2026, Australia Academic Press Pty Ltd

    Salvatore Nesci

  3. The Dopaminergic Energy Crisis of Adolescent Depression: Mitochondrial Bioenergetics Control of Nucleus Accumbens Signaling

    Article • Neuroscience Bulletin, June 2026, Springer Science + Business Media

    Salvatore Nesci

  4. A Biphasic Mitochondrial Damage‐Management System: The Mitochondrial Derived Vescicles as Yin and Yang

    Article • Journal of Biochemical and Molecular Toxicology, June 2026, Wiley

    Salvatore Nesci

  5. Mitochondrial Complex IV in Free form Controls Respiratory Channeling Independently of Supercomplex Assembly

    Article • Translational Insights, May 2026, Australia Academic Press Pty Ltd

    Salvatore Nesci

  6. Mitochondrial Dysfunction in the Inflammatory Process of Neurodegenerative Diseases

    Article • Biomedicines, March 2026, MDPI AG

    Salvatore Nesci

  7. Metabolic Comparison of Mature and Immature Bovine Cumulus–Oocyte Complexes with Standardization of Bioenergetic Assessment

    Article • Biomolecules, February 2026, MDPI AG

    Salvatore Nesci

  8. Dextromethorphan Is a Novel Pharmacological Inhibitor of F 1 F O ‐ ...

    Article • BioFactors, January 2026, Wiley

    Salvatore Nesci

  9. Mitochondrial Permeability Transition Pore: The Cardiovascular Disease’s Molecular Achilles Heel

    Article • Biomedicines, December 2025, MDPI AG

    Salvatore Nesci

  10. Reprogramming the Mitochondrion in Atherosclerosis: Targets for Vascular Protection

    Article • Antioxidants, December 2025, MDPI AG

    Salvatore Nesci

  11. Inflammatory mitochondrial signalling and viral mimicry in cancer

    Article • Journal of Translational Medicine, September 2025, Springer Science + Business Media

    Salvatore Nesci

  12. Oxygen Deprivation and Brain Inflammation: The Mitochondrial Link to Alzheimer's Progression

    Article • Journal of Biochemical and Molecular Toxicology, September 2025, Wiley

    Salvatore Nesci

  13. Mitochondrial bioenergetics analysis on SLC-selected boar spermatozoa during liquid storage

    Article • Animal Reproduction Science, July 2025, Elsevier

    Salvatore Nesci

  14. Analysis of stallion spermatozoa metabolism using Agilent Seahorse XFp Technology

    Article • Animal Reproduction Science, December 2024, Elsevier

    Salvatore Nesci

  15. Mitochondrial sirtuin 3 and role of natural compounds: the effect of post-translational modifications on cellular metabolism

    Article • Critical Reviews in Biochemistry and Molecular Biology, July 2024, Taylor & Francis

    Salvatore Nesci

  16. UCP2, a Member of the Mitochondrial Uncoupling Proteins: An Overview from Physiological to Pathological Roles

    Article • Biomedicines, June 2024, MDPI AG

    Salvatore Nesci

  17. H+‐slip correlated to rotor free‐wheeling as cause of F1FO‐ATPase dysfunction in primary mitochondrial disorders

    Article • Medicinal Research Reviews, January 2024, Wiley

    Salvatore Nesci

  18. Selenite ameliorates the ATP hydrolysis of mitochondrial F1FO-ATPase by changing the redox state of thiol groups and impairs the ADP phosphorylation

    Article • Free Radical Biology and Medicine, January 2024, Elsevier

    Salvatore Nesci

  19. Understanding differential aspects of microdiffusion (channeling) in the Coenzyme Q and Cytochrome c regions of the mitochondrial respiratory system

    Article • Mitochondrion, January 2024, Elsevier

    Salvatore Nesci

  20. Mineralocorticoid Receptor Antagonism Prevents Type 2 Familial Partial Lipodystrophy Brown Adipocyte Dysfunction

    Article • Cells, November 2023, MDPI AG

    Salvatore Nesci

  21. Proton leak through the UCPs and ANT carriers and beyond: A breath for the electron transport chain

    Article • Biochimie, November 2023, Elsevier

    Salvatore Nesci

  22. Inflammatory signaling in NASH driven by hepatocyte mitochondrial dysfunctions

    Article • Journal of Translational Medicine, October 2023, Springer Science + Business Media

    Salvatore Nesci

  23. Cell bioenergetics and ATP production of boar spermatozoa

    Article • Theriogenology, October 2023, Elsevier

    Salvatore Nesci

  24. Cell Metabolism Therapy by Small Natural Compounds

    Article • International Journal of Molecular Sciences, September 2023, MDPI AG

    Salvatore Nesci

  25. Two separate pathways underlie NADH and succinate oxidation in swine heart mitochondria: Kinetic evidence on the mobile electron carriers

    Article • Biochimica et Biophysica Acta (BBA) - Bioenergetics, August 2023, Elsevier

    Salvatore Nesci

  26. Inflammation, Mitochondria and Natural Compounds Together in the Circle of Trust

    Article • International Journal of Molecular Sciences, March 2023, MDPI AG

    Salvatore Nesci

  27. Novel Regioselective Synthesis of 1,3,4,5-Tetrasubstituted Pyrazoles and Biochemical Valuation on F1FO-ATPase and Mitochondrial Permeability Transition Pore Formation

    Article • Pharmaceutics, February 2023, MDPI AG

    Salvatore Nesci

  28. ‘Rotor free-wheeling’ in impaired F1FO-ATPase induces congenital hypermetabolism

    Article • Trends in Endocrinology and Metabolism, February 2023, Elsevier

    Salvatore Nesci

  29. GPR35, ally of the anti-ischemic ATPIF1-ATP synthase interaction

    Article • Trends in Pharmacological Sciences, November 2022, Elsevier

    Salvatore Nesci

  30. Effects of cryopreservation on the mitochondrial bioenergetics of bovine sperm

    Article • Reproduction in Domestic Animals, September 2022, Wiley

    Salvatore Nesci

  31. The Impairment of Cell Metabolism by Cardiovascular Toxicity of Doxorubicin Is Reversed by Bergamot Polyphenolic Fraction Treatment in Endothelial Cells

    Article • International Journal of Molecular Sciences, August 2022, MDPI AG

    Salvatore Nesci

  32. Cellular Metabolism and Bioenergetic Function in Human Fibroblasts and Preadipocytes of Type 2 Familial Partial Lipodystrophy

    Article • International Journal of Molecular Sciences, August 2022, MDPI AG

    Salvatore Nesci

  33. What happens when the mitochondrial H+-translocating F1FO-ATP(hydrol)ase becomes a molecular target of calcium? The pore opens

    Article • Biochimie, July 2022, Elsevier

    Salvatore Nesci

  34. Protein folding and unfolding: proline cis‐trans isomerization at the c subunits of F1FO‐ATPase might open a high conductance ion channel

    Article • Proteins Structure Function and Bioinformatics, May 2022, Wiley

    Salvatore Nesci

  35. Mitochondria Bioenergetic Functions and Cell Metabolism Are Modulated by the Bergamot Polyphenolic Fraction

    Article • Cells, April 2022, MDPI AG

    Salvatore Nesci

  36. From the Structural and (Dys)Function of ATP Synthase to Deficiency in Age-Related Diseases

    Article • Life, March 2022, MDPI AG

    Salvatore Nesci

  37. From the Structural and (Dys)function of ATP Synthase to Deficiency in Age-Related Diseases

    Article • February 2022, MDPI AG

    Salvatore Nesci

  38. Impaired Mitochondrial Bioenergetics under Pathological Conditions

    Article • Life, January 2022, MDPI AG

    Salvatore Nesci

  39. Protein folding and unfolding: proline cis - trans isomerization at the c subunits of F 1 F O -ATPase might open a high conductance ion channel

    Article • January 2022, Wiley

    Salvatore Nesci

  40. Unraveling Energy Substrate Utilization in Sperm Cells

    Article • Animal Reproduction, January 2022, FapUNIFESP (SciELO)

    Dr. Ivan Cunha Bustamante Filho, Salvatore Nesci

  41. Enjoy your journey: the bergamot polyphenols from the tree to the cell metabolism

    Article • Journal of Translational Medicine, November 2021, Springer Science + Business Media

    Salvatore Nesci

  42. The mitochondrial F1FO-ATPase exploits the dithiol redox state to modulate the permeability transition pore

    Article • Archives of Biochemistry and Biophysics, November 2021, Elsevier

    Salvatore Nesci

  43. SARS‐CoV‐2 first contact: Spike–ACE2 interactions in COVID‐19

    Article • Chemical Biology & Drug Design, June 2021, Wiley

    Salvatore Nesci

  44. Sulfide affects the mitochondrial respiration, the Ca2+-activated F1FO-ATPase activity and the permeability transition pore but does not change the Mg2+-activated F1FO-ATPase activity in swine heart mitochondria

    Article • Pharmacological Research, April 2021, Elsevier

    Salvatore Nesci

  45. Relationship between serum concentration, functional parameters and cell bioenergetics in IPEC-J2 cell line

    Article • Histochemistry and Cell Biology, March 2021, Springer Science + Business Media

    Salvatore Nesci

  46. Molecular and Supramolecular Structure of the Mitochondrial Oxidative Phosphorylation System: Implications for Pathology

    Article • Life, March 2021, MDPI AG

    Salvatore Nesci

  47. Biological characteristics and metabolic profile of canine mesenchymal stem cells isolated from adipose tissue and umbilical cord matrix

    Article • PLOS One, March 2021, PLOS

    Salvatore Nesci

  48. Ca2+ as cofactor of the mitochondrial H+‐translocating F1FO‐ATP(hydrol)ase

    Article • Proteins Structure Function and Bioinformatics, January 2021, Wiley

    Salvatore Nesci

  49. Mitochondrial F1FO-ATPase and permeability transition pore response to sulfide in the midgut gland of Mytilus galloprovincialis

    Article • Biochimie, January 2021, Elsevier

    Salvatore Nesci

  50. Incoming news on the F-type ATPase structure and functions in mammalian mitochondria

    Article • January 2021, Elsevier

    Salvatore Nesci

  51. The Ca2+ as cofactor of mitochondrial H+-translocating F1FO-ATP(hydrol)ase

    Article • October 2020, Wiley

    Salvatore Nesci

  52. 1,5‐Disubstituted‐1,2,3‐triazoles as inhibitors of the mitochondrial Ca 2+ ‐activated F 1 F O ‐ATP(hydrol)ase and the permeability transition pore

    Article • Annals of the New York Academy of Sciences, September 2020, Wiley

    Salvatore Nesci

  53. Effects of Hydrogen Sulfide Donor NaHS on Porcine Vascular Wall-Mesenchymal Stem Cells

    Article • International Journal of Molecular Sciences, July 2020, MDPI AG

    Salvatore Nesci

  54. Mitochondrial F-type ATP synthase: multiple enzyme functions revealed by the membrane-embedded FO structure

    Article • Critical Reviews in Biochemistry and Molecular Biology, June 2020, Taylor & Francis

    Salvatore Nesci

  55. Nicotinamide Nucleotide Transhydrogenase as a Sensor of Mitochondrial Biology

    Article • Trends in Cell Biology, November 2019, Elsevier

    Salvatore Nesci

  56. The mitochondrial permeability transition pore in cell death: A promising drug binding bioarchitecture

    Article • Medicinal Research Reviews, October 2019, Wiley

    Salvatore Nesci

  57. Mitochondrial Ca 2+ ‐activated F 1 F O ‐ATPase hydrolyzes ATP and promotes the permeability transition pore

    Article • Annals of the New York Academy of Sciences, August 2019, Wiley

    Salvatore Nesci

  58. Emerging Roles for the Mitochondrial ATP Synthase Supercomplexes

    Article • Trends in Biochemical Sciences, August 2019, Elsevier

    Salvatore Nesci

  59. A Therapeutic Role for the F1FO-ATP Synthase

    Article • SLAS DISCOVERY, July 2019, SAGE Publications

    Salvatore Nesci

  60. Characterization of metabolic profiles and lipopolysaccharide effects on porcine vascular wall mesenchymal stem cells

    Article • Journal of Cellular Physiology, March 2019, Wiley

    Salvatore Nesci

  61. Crucial aminoacids in the FO sector of the F1FO-ATP synthase address H+ across the inner mitochondrial membrane: molecular implications in mitochondrial dysfunctions

    Article • Amino Acids, February 2019, Springer Science + Business Media

    Salvatore Nesci

  62. Lipid-protein interactions in mitochondrial membranes from bivalve mollusks: molecular strategies in different species

    Article • Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology, January 2019, Elsevier

    Salvatore Nesci

  63. From the Ca 2+ -activated F 1 F O -ATPase to the mitochondrial permeability transition pore: an overview

    Article • Biochimie, June 2018, Elsevier

    Salvatore Nesci

  64. A Lethal Channel between the ATP Synthase Monomers

    Article • Trends in Biochemical Sciences, March 2018, Elsevier

    Salvatore Nesci

  65. New insight in a new entity: the mitochondrial permeability transition pore arises from the Ca 2+ -activated F 1 F O -ATPases

    Article • Science Bulletin, February 2018, Elsevier

    Salvatore Nesci

  66. The inhibition of the mitochondrial F1FO-ATPase activity when activated by Ca2+ opens new regulatory roles for NAD+

    Article • Biological Chemistry, January 2018, De Gruyter

    Salvatore Nesci

  67. Mitochondrial permeability transition, F 1 F O ‐ATPase and calcium: an enigmatic triangle

    Article • EMBO Reports, December 2017, EMBO

    Salvatore Nesci

  68. Post-translational modifications of the mitochondrial F 1 F O -ATPase

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, November 2017, Elsevier

    Salvatore Nesci

  69. A preliminary study on a novel sea water disinfection process by a peroxy-acid compound to complement and improve the microbial depuration of clams ( Ruditapes philippinarum )

    Article • Food Control, October 2017, Elsevier

    Salvatore Nesci

  70. Kinetic properties of the mitochondrial F 1 F O -ATPase activity elicited by Ca 2+ in replacement of Mg 2+

    Article • Biochimie, September 2017, Elsevier

    Salvatore Nesci

  71. Mitochondrial permeability transition, F 1 F O ‐ATPase and calcium: an enigmatic triangle

    Article • EMBO Reports, July 2017, EMBO

    Salvatore Nesci

  72. Glucose and glutamine in the mitochondrial oxidative metabolism of stem cells

    Article • Mitochondrion, July 2017, Elsevier

    Salvatore Nesci

  73. Mercury and protein thiols: Stimulation of mitochondrial F1FO-ATPase and inhibition of respiration

    Article • Chemico-Biological Interactions, December 2016, Elsevier

    Salvatore Nesci

  74. Preferential nitrite inhibition of the mitochondrial F1FO-ATPase activities when activated by Ca2+ in replacement of the natural cofactor Mg2+

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, February 2016, Elsevier

    Salvatore Nesci

  75. Lipid unsaturation per se does not explain the physical state of mitochondrial membranes in Mytilus galloprovincialis

    Article • Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology, January 2016, Elsevier

    Salvatore Nesci

  76. Thiol-Related Regulation of the Mitochondrial F1FO-ATPase Activity

    Article • December 2015, Springer Science + Business Media

    Salvatore Nesci

  77. The c-Ring of the F1FO-ATP Synthase: Facts and Perspectives

    Article • The Journal of Membrane Biology, November 2015, Springer Science + Business Media

    Salvatore Nesci

  78. Opposite Rotation Directions in the Synthesis and Hydrolysis of ATP by the ATP Synthase: Hints from a Subunit Asymmetry

    Article • The Journal of Membrane Biology, February 2015, Springer Science + Business Media

    Salvatore Nesci

  79. Long-chain PUFA enrichment in microalgae and metabolic dynamics inTapes philippinarumlarvae

    Article • Aquaculture Nutrition, February 2015, Wiley

    Salvatore Nesci

  80. The a subunit asymmetry dictates the two opposite rotation directions in the synthesis and hydrolysis of ATP by the mitochondrial ATP synthase

    Article • Medical Hypotheses, January 2015, Elsevier

    Salvatore Nesci

  81. Thiol oxidation of mitochondrial FO-c subunits: A way to switch off antimicrobial drug targets of the mitochondrial ATP synthase

    Article • Medical Hypotheses, August 2014, Elsevier

    Salvatore Nesci

  82. Thiol oxidation is crucial in the desensitization of the mitochondrial F1FO-ATPase to oligomycin and other macrolide antibiotics

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, June 2014, Elsevier

    Salvatore Nesci

  83. The mitochondrial F1FO-ATPase desensitization to oligomycin by tributyltin is due to thiol oxidation

    Article • Biochimie, February 2014, Elsevier

    Salvatore Nesci

  84. Modifiers of the oligomycin sensitivity of the mitochondrial F1F0-ATPase

    Article • Mitochondrion, July 2013, Elsevier

    Salvatore Nesci

  85. Mussel and mammalian ATP synthase share the same bioenergetic cost of ATP

    Article • Journal of Bioenergetics and Biomembranes, March 2013, Springer Science + Business Media

    Salvatore Nesci

  86. Toxicity of organotin compounds: Shared and unshared biochemical targets and mechanisms in animal cells

    Article • Toxicology in Vitro, March 2013, Elsevier

    Salvatore Nesci

  87. Modulation of the F1FO-ATPase function by butyltin compounds

    Article • Applied Organometallic Chemistry, February 2013, Wiley

    Salvatore Nesci

  88. Dietary Enhancement of Selected Fatty Acid Biosynthesis in the Digestive Gland of Mytilus galloprovincialis Lmk.

    Article • Journal of Agricultural and Food Chemistry, January 2013, American Chemical Society (ACS)

    Salvatore Nesci

  89. Tri-n-butyltin binding to a low-affinity site decreases the F1FO-ATPase sensitivity to oligomycin in mussel mitochondria

    Article • Applied Organometallic Chemistry, September 2012, Wiley

    Salvatore Nesci

  90. Organotin Effects in Different Phyla: Discrepancies and Similarities

    Article • March 2012, Bentham Science Publishers

    Salvatore Nesci

  91. Tributyltin-driven enhancement of the DCCD insensitive Mg-ATPase activity in mussel digestive gland mitochondria

    Article • Biochimie, March 2012, Elsevier

    Salvatore Nesci

  92. Structural and functional changes in gill mitochondrial membranes from the Mediterranean mussel Mytilus galloprovincialis exposed to tri-n-butyltin

    Article • Environmental Toxicology and Chemistry, February 2012, Wiley

    Salvatore Nesci

  93. Multi-site TBT binding skews the inhibition of oligomycin on the mitochondrial Mg–ATPase in Mytilus galloprovincialis

    Article • Biochimie, July 2011, Elsevier

    Salvatore Nesci

  94. Tributyltin (TBT) and mitochondrial respiration in mussel digestive gland

    Article • Toxicology in Vitro, June 2011, Elsevier

    Salvatore Nesci

  95. Tributyltin (TBT) and dibutyltin (DBT) differently inhibit the mitochondrial Mg-ATPase activity in mussel digestive gland

    Article • Toxicology in Vitro, February 2011, Elsevier

    Salvatore Nesci

  96. Tributyltin inhibits the oligomycin-sensitive Mg-ATPase activity in Mytilus galloprovincialis digestive gland mitochondria

    Article • Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology, January 2011, Elsevier

    Salvatore Nesci

  97. Tributyltin (TBT) inhibition of oligomycin-sensitive Mg-ATPase activity in mussel mitochondria

    Article • Toxicology in Vitro, June 2008, Elsevier

    Salvatore Nesci