All Stories

  1. A new era in dietary supplement regulation: sustainable chemometric approach for quality control of four dietary ingredients in slimming preparations

    Article • Journal of Food Composition and Analysis, December 2025, Elsevier

    Said A. Hassan

  2. Micellar-enhanced synchronous spectrofluorimetric determination of anticancer trans-Resveratrol: a sustainable quality control tool for dietary supplements integrating circular analytical chemistry in the post-reform FDA era

    Article • Microchemical Journal, December 2025, Elsevier

    Said A. Hassan

  3. An eco-friendly potentiometric sensor for in-line monitoring of methacholine chloride hydrolysis: A ‘Green-Dip’ approach

    Article • Journal of Electroanalytical Chemistry, November 2025, Elsevier

    Said A. Hassan

  4. A Stability indicating TLC-Densitometric Method for the Determination of Remdesivir in presence of Its Degradation Products

    Article • Zagazig Journal of Pharmaceutical Sciences, July 2025, Egypts Presidential Specialized Council for Education and Scientific Research

    Said A. Hassan

  5. Eco-friendly spectrofluorimetric determination of remdesivir in the presence of its metabolite in human plasma for therapeutic monitoring in COVID-19 patients

    Article • Scientific Reports, June 2025, Springer Science + Business Media

    Said A. Hassan

  6. Impurity profiling of paracetamol toxic impurities in pharmaceutical combination with ibuprofen and chlorzoxazone using HPLC and TLC densitometric methods

    Article • BMC Chemistry, April 2025, Springer Science + Business Media

    Said A. Hassan

  7. Novel carbon paste sensor modified with MWCNT and Ca-doped ZnO nanocomposite for therapeutic monitoring of Favipiravir in COVID-19 patients

    Article • Microchemical Journal, January 2025, Elsevier

    Said A. Hassan

  8. New chemometrics-assisted spectrophotometric methods for simultaneous determination of co-formulated drugs montelukast, rupatadine, and desloratadine in their different dosage combinations

    Article • BMC Chemistry, November 2024, Springer Science + Business Media

    Said A. Hassan

  9. The Problem of Worst-Case Variability in Cleaning Validation and Cross-Contamination Control: A Quality by Design Approach on Some Cephalosporin Residuals

    Article • Journal of Analytical Chemistry, July 2024, Pleiades Publishing Ltd

    Said A. Hassan

  10. Monitoring of the prohibited 2-phenethylamine in dietary supplements using a t-Butyl calix[8]arene/Ag/CuO composite-based potentiometric sensor

    Article • Microchemical Journal, June 2024, Elsevier

    Said A. Hassan

  11. Advanced chemometric methods for simultaneous quantitation of caffeine, codeine, paracetamol, and p-aminophenol in their quaternary mixture

    Article • Scientific Reports, January 2024, Springer Science + Business Media

    Said A. Hassan

  12. A solvent-free HPLC method for the simultaneous determination of Favipiravir and its hydrolytic degradation product

    Article • Scientific Reports, October 2023, Springer Science + Business Media

    Said A. Hassan

  13. Continuous wavelet transform for solving the problem of minor components in quantitation of pharmaceuticals: a case study on the mixture of ibuprofen and phenylephrine with its degradation products

    Article • BMC Chemistry, October 2023, Springer Science + Business Media

    Said A. Hassan

  14. Development of an eco-friendly HPLC method for the stability indicating assay of binary mixture of ibuprofen and phenylephrine

    Article • BMC Chemistry, October 2023, Springer Science + Business Media

    Said A. Hassan

  15. Design of Solid-contact Ion-selective Electrode with Multiwall-carbon Nanotubes for Assay of Sulfacetamide in Rabbit Aqueous Humour

    Article • Current Analytical Chemistry, July 2023, Bentham Science Publishers

    Mona Mohamed, Said A. Hassan

  16. Development and Bioanalytical Validation of RP-HPLC Method for the Simultaneous Determination of Perampanel and Carbamazepine in Human Plasma for Therapeutic Drug Monitoring

    Article • Journal of Analytical Chemistry, May 2023, Pleiades Publishing Ltd

    Said A. Hassan

  17. Fluorescence imaging approaches for eco‐friendly determination of perampanel in human plasma and application for therapeutic drug monitoring

    Article • Luminescence, April 2023, Wiley

    Said A. Hassan

  18. Development of an eco-friendly HPLC method for the stability indicating assay of binary mixture of ibuprofen and phenylephrine

    Article • March 2023, Research Square

    Said A. Hassan

  19. Dietary supplement mislabelling: case study on selected slimming products by developing a green isocratic HPLC method for their quality control

    Article • Scientific Reports, December 2022, Springer Science + Business Media

    Said A. Hassan

  20. Novel microfabricated solid-contact potentiometric sensors doped with multiwall carbon-nanotubes for simultaneous determination of bisoprolol and perindopril in spiked human plasma

    Article • Microchemical Journal, July 2022, Elsevier

    Said A. Hassan

  21. Signal processing techniques for the spectrophotometric quantitation of binary mixture of dapagliflozin and saxagliptin: A comparative study

    Article • Tropical Journal of Pharmaceutical Research, February 2022, African Journals Online (AJOL)

    Said A. Hassan

  22. Advanced chemometric methods as powerful tools for impurity profiling of drug substances and drug products: Application on bisoprolol and perindopril binary mixture

    Article • Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, February 2022, Elsevier

    Said A. Hassan

  23. Quality control of dietary supplements: An economic green spectrofluorimetric assay of Raspberry ketone and its application to weight variation testing

    Article • Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, November 2021, Elsevier

    Said A. Hassan

  24. Microfabricated potentiometric sensor for personalized methacholine challenge tests during the COVID-19 pandemic

    Article • Biosensors and Bioelectronics, October 2021, Elsevier

    Said A. Hassan

  25. Different spectrophotometric methods manipulating ratio spectra for the assay of hydrocortisone acetate and clioquinol in their topical preparation

    Article • European Journal of Chemistry, September 2021, European Journal of Chemistry

    Said A. Hassan

  26. Supramolecular green chemistry; An eco-friendly spectrophotometric approach for determination of non-chromophoric methacholine via host-guest interactions with 4-sulfocalix[4]arene

    Article • Microchemical Journal, September 2021, Elsevier

    Said A. Hassan

  27. Optimization of localized surface plasmon resonance hot spots in surface-enhanced infrared absorption spectroscopy aluminum substrate as an optical sensor coupled to chemometric tools for the purity assay of quinary mixtures

    Article • Microchimica Acta, May 2021, Springer Science + Business Media

    Said A. Hassan

  28. Simultaneous Determination of Amlodipine and Olmesartan Using HPLC with Fluorescence Detection

    Article • Pharmaceutical Chemistry Journal, May 2021, Springer Science + Business Media

    Said A. Hassan

  29. Development, Optimization, and Validation of a Green Spectrofluorimetric method for the determination of Moxifloxacin using an Experimental design approach

    Article • Research Journal of Pharmacy and Technology, April 2021, A and V Publications

    Said A. Hassan

  30. Analytical quality by design approach for the control of potentially counterfeit chloroquine with some NSAIDS using HPLC with fluorescence detection in pharmaceutical preparation and breast milk

    Article • Acta Chromatographica, April 2021, Akademiai Kiado

    Said A. Hassan

  31. A comparative study of two analytical techniques for the simultaneous determination of amprolium HCl and ethopabate from combined dosage form and in presence of their alkaline degradation

    Article • Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, December 2020, Elsevier

    Said A. Hassan

  32. Comparative kinetic studies and pH-rate profiling of aniracetam degradation using validated stability-indicating RP-HPLC method

    Article • Microchemical Journal, September 2020, Elsevier

    Said A. Hassan

  33. Point-of-care diagnostics for drugs of abuse in biological fluids: application of a microfabricated disposable copper potentiometric sensor

    Article • Microchimica Acta, August 2020, Springer Science + Business Media

    Said A. Hassan

  34. Stability-Indicating RP-HPLC and CE Methods for Simultaneous Determination of Bisoprolol and Perindopril in Pharmaceutical Formulation: A Comparative Study

    Article • Journal of Chromatographic Science, July 2020, Oxford University Press (OUP)

    Said A. Hassan

  35. Spectrofluorimetric study on fluorescence quenching of tyrosine and l‐tryptophan by the aniracetam cognition enhancer drug: quenching mechanism using Stern–Volmer and double‐log plots

    Article • Luminescence, January 2020, Wiley

    Said A. Hassan

  36. Strategies for stabilizing formulation and QbD assisted development of robust stability indicating method of azilsartan medoxomil/chlorthalidone

    Article • Journal of Pharmaceutical and Biomedical Analysis, January 2020, Elsevier

    Said A. Hassan

  37. Multivariate Development and Optimization of Stability Indicating Method for Determination of Daclatasvir in Presence of Potential Degradation Products

    Article • Chromatographia, August 2019, Springer Science + Business Media

    Said A. Hassan

  38. Application of wavelet and Fuorier transforms as powerful alternatives for derivative spectrophotometry in analysis of binary mixtures: A comparative study

    Article • Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, February 2018, Elsevier

    Said A. Hassan

  39. Development and validation of LC–MS/MS assay for the simultaneous determination of methotrexate, 6-mercaptopurine and its active metabolite 6-thioguanine in plasma of children with acute lymphoblastic leukemia: Correlation with genetic polymorphism

    Article • Journal of Chromatography B, December 2016, Elsevier

    Said A. Hassan

  40. Development and validation of HPLC and CE methods for simultaneous determination of amlodipine and atorvastatin in the presence of their acidic degradation products in tablets

    Article • Acta Pharmaceutica, October 2016, De Gruyter

    Said A. Hassan

  41. In-line potentiometric monitoring of dissolution behavior of verapamil hydrochloride versus traditional pharmacopeial method: A comparative study

    Article • Sensors and Actuators B Chemical, June 2016, Elsevier

    Said A. Hassan

  42. Advanced stability indicating chemometric methods for quantitation of amlodipine and atorvastatin in their quinary mixture with acidic degradation products

    Article • Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, February 2016, Elsevier

    Said A. Hassan

  43. Mean centering of double divisor ratio spectra, a novel spectrophotometric method for analysis of ternary mixtures

    Article • Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, January 2016, Elsevier

    Said A. Hassan

  44. Continuous Wavelet Transform, a powerful alternative to Derivative Spectrophotometry in analysis of binary and ternary mixtures: A comparative study

    Article • Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, December 2015, Elsevier

    Said A. Hassan

  45. Different signal processing techniques of ratio spectra for spectrophotometric resolution of binary mixture of bisoprolol and hydrochlorothiazide; a comparative study

    Article • Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, April 2015, Elsevier

    Said A. Hassan

  46. Different approaches in Partial Least Squares and Artificial Neural Network models applied for the analysis of a ternary mixture of Amlodipine, Valsartan and Hydrochlorothiazide

    Article • Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, March 2014, Elsevier

    Said A. Hassan

  47. Sequential Spectrophotometric Method for the Simultaneous Determination of Amlodipine, Valsartan, and Hydrochlorothiazide in Coformulated Tablets

    Article • International Journal of Spectroscopy, December 2013, Hindawi Publishing Corporation

    Said A. Hassan

  48. Comparative study between derivative spectrophotometry and multivariate calibration as analytical tools applied for the simultaneous quantitation of Amlodipine, Valsartan and Hydrochlorothiazide

    Article • Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, September 2013, Elsevier

    Said A. Hassan

  49. Three different methods for determination of binary mixture of Amlodipine and Atorvastatin using dual wavelength spectrophotometry

    Article • Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, March 2013, Elsevier

    Said A. Hassan

  50. Three different spectrophotometric methods manipulating ratio spectra for determination of binary mixture of Amlodipine and Atorvastatin

    Article • Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, December 2011, Elsevier

    Said A. Hassan