All Stories

  1. Evaluation of pharmacokinetic pharmacodynamic target attainment of meropenem in pediatric patients

    Article • Pediatrics & Neonatology, July 2024, Elsevier

    Assistant Professor Saeed Alqahtani

  2. Colorectal cancer-related resource utilization and healthcare costs in Saudi Arabia

    Article • Saudi Pharmaceutical Journal, November 2023, Springer Science + Business Media

    Assistant Professor Saeed Alqahtani

  3. Cross-national comparative study of orphan drug policies in Saudi Arabia, the United States, and the European Union

    Article • Saudi Pharmaceutical Journal, September 2023, Springer Science + Business Media

    Assistant Professor Saeed Alqahtani

  4. Population Pharmacokinetics of Rivaroxaban in Real‐World Patients

    Article • The Journal of Clinical Pharmacology, May 2023, Wiley

    Assistant Professor Saeed Alqahtani

  5. Assessment of Micafungin Dosage Regimens in Patients with Cancer Using Pharmacokinetic/Pharmacodynamic Modeling and Monte Carlo Simulation

    Article • Antibiotics, November 2021, MDPI AG

    Assistant Professor Saeed Alqahtani

  6. Sinapic acid mitigates methotrexate‐induced hepatic injuries in rats through modulation of Nrf‐2/ HO ‐1 signaling

    Article • Environmental Toxicology, March 2021, Wiley

    Assistant Professor Saeed Alqahtani

  7. Estimation of Tacrolimus Clearance in Saudi Adult Kidney Transplant Recipients

    Article • Saudi Journal of Kidney Diseases and Transplantation, January 2021, Medknow

    Assistant Professor Saeed Alqahtani

  8. Multi-Therapeutic Potential of Naringenin (4′,5,7-Trihydroxyflavonone): Experimental Evidence and Mechanisms

    Article • Plants, December 2020, MDPI AG

    Assistant Professor Saeed Alqahtani

  9. Optimization of Vancomycin Dosing Regimen in Cancer Patients using Pharmacokinetic/Pharmacodynamic Modeling

    Article • Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy, November 2020, Wiley

    Assistant Professor Saeed Alqahtani

  10. Clinical pharmacology applications in clinical drug development and clinical care: A focus on Saudi Arabia

    Article • Saudi Pharmaceutical Journal, October 2020, Springer Science + Business Media

    Assistant Professor Saeed Alqahtani

  11. Drug utilization and expenditure of anticancer drugs for breast cancer

    Article • Saudi Pharmaceutical Journal, June 2020, Springer Science + Business Media

    Assistant Professor Saeed Alqahtani

  12. Estimation of lithium clearance in patients with bipolar disorder

    Article • International Clinical Psychopharmacology, May 2020, Wolters Kluwer Health

    Assistant Professor Saeed Alqahtani

  13. Gender effect on the pharmacokinetics of thymoquinone: Preclinical investigation and in silico modeling in male and female rats

    Article • Saudi Pharmaceutical Journal, April 2020, Springer Science + Business Media

    Assistant Professor Saeed Alqahtani

  14. Appropriate therapeutic drug monitoring of antibiotics contributed to lower nephrotoxicity

    Article • International Journal of Clinical Pharmacology and Therapeutics, February 2020, Dustri-Verlgag Dr. Karl Feistle

    Assistant Professor Saeed Alqahtani

  15. Exploring the value of a Doctor of Philosophy program in Pharmaceutical Outcomes and Policy Research in Saudi Arabia

    Article • Saudi Pharmaceutical Journal, January 2020, Springer Science + Business Media

    Assistant Professor Saeed Alqahtani

  16. Antidiabetic, antioxidant, molecular docking and HPTLC analysis of miquelianin isolated from Euphorbia schimperi C. Presl

    Article • Saudi Pharmaceutical Journal, July 2019, Springer Science + Business Media

    Assistant Professor Saeed Alqahtani

  17. Estimation of apparent clearance of valproic acid in adult Saudi patients

    Article • International Journal of Clinical Pharmacy, June 2019, Springer Science + Business Media

    Assistant Professor Saeed Alqahtani

  18. Estimation of Phenytoin Pharmacokinetic Parameters in Saudi Epileptic Patients

    Article • Pharmacology, January 2019, Karger Publishers

    Assistant Professor Saeed Alqahtani

  19. Optimizing Vancomycin Monitoring in Pediatric Patients

    Article • The Pediatric Infectious Disease Journal, September 2018, Wolters Kluwer Health

    Assistant Professor Saeed Alqahtani

  20. An update on the potential role of intestinal first-pass metabolism for the prediction of drug–drug interactions: the role of PBPK modeling

    Article • Expert Opinion on Drug Metabolism & Toxicology, June 2018, Taylor & Francis

    Assistant Professor Saeed Alqahtani

  21. Epidermal growth factor receptor (EGFR) inhibitor PD153035 reverses ABCG2-mediated multidrug resistance in non-small cell lung cancer: In vitro and in vivo

    Article • Cancer Letters, June 2018, Elsevier

    Assistant Professor Saeed Alqahtani

  22. Population Pharmacokinetic Model for Vancomycin Used in Open Heart Surgery: Model-Based Evaluation of Standard Dosing Regimens

    Article • Antimicrobial Agents and Chemotherapy, April 2018, ASM Journals

    Assistant Professor Saeed Alqahtani

  23. Optimizing Amikacin Dosage in Pediatrics Based on Population Pharmacokinetic/Pharmacodynamic Modeling

    Article • Pediatric Drugs, March 2018, Springer Science + Business Media

    Assistant Professor Saeed Alqahtani

  24. Population Pharmacokinetic Model-Based Evaluation of Standard Dosing Regimens for Cefuroxime Used in Coronary Artery Bypass Graft Surgery with Cardiopulmonary Bypass

    Article • Antimicrobial Agents and Chemotherapy, January 2018, ASM Journals

    Assistant Professor Saeed Alqahtani

  25. In silico ADME-Tox modeling: progress and prospects

    Article • Expert Opinion on Drug Metabolism & Toxicology, October 2017, Taylor & Francis

    Assistant Professor Saeed Alqahtani

  26. Thiazole-valine peptidomimetic (TTT-28) antagonizes multidrug resistance in vitro and in vivo by selectively inhibiting the efflux activity of ABCB1

    Article • Scientific Reports, February 2017, Springer Science + Business Media

    Assistant Professor Saeed Alqahtani

  27. Transporters as Drug Targets in Neurological Diseases

    Article • Clinical Pharmacology & Therapeutics, August 2016, Wiley

    Assistant Professor Saeed Alqahtani , Prof Mohamed Abdel-Latif

  28. PEGylation Enhances the Oral Bioavailability of γ-Tocotrienol Isomer of Vitamin E

    Article • March 2016, Institute of Electrical & Electronics Engineers (IEEE)

    Assistant Professor Saeed Alqahtani

  29. Development of a Physiologically Based Pharmacokinetic/Pharmacodynamic Model to Predict the Impact of Genetic Polymorphisms on the Pharmacokinetics and Pharmacodynamics Represented by Receptor/Transporter Occupancy of Central Nervous System Drugs

    Article • Clinical Pharmacokinetics, February 2016, Springer Science + Business Media

    Assistant Professor Saeed Alqahtani

  30. Development of a physiologically based pharmacokinetic/pharmacodynamic model to identify mechanisms contributing to entacapone low bioavailability

    Article • Biopharmaceutics & Drug Disposition, December 2015, Wiley

    Assistant Professor Saeed Alqahtani

  31. Extra-virgin olive oil attenuates amyloid-β and tau pathologies in the brains of TgSwDI mice

    Article • The Journal of Nutritional Biochemistry, December 2015, Elsevier

    Assistant Professor Saeed Alqahtani , Prof Mohamed Abdel-Latif

  32. Development of Physiologically Based Pharmacokinetic/Pharmacodynamic Model for Indomethacin Disposition in Pregnancy

    Article • PLOS One, October 2015, PLOS

    Assistant Professor Saeed Alqahtani

  33. PEGylated γ-tocotrienol isomer of vitamin E: Synthesis, characterization, in vitro cytotoxicity, and oral bioavailability

    Article • European Journal of Pharmaceutics and Biopharmaceutics, October 2015, Elsevier

    Hassan Y. Ebrahim, PhD, Assistant Professor Saeed Alqahtani

  34. Orlistat limits cholesterol intestinal absorption by Niemann-pick C1-like 1 (NPC1L1) inhibition

    Article • European Journal of Pharmacology, September 2015, Elsevier

    Assistant Professor Saeed Alqahtani

  35. Cellular uptake, antioxidant and antiproliferative activity of entrapped α-tocopherol and γ-tocotrienol in poly (lactic-co-glycolic) acid (PLGA) and chitosan covered PLGA nanoparticles (PLGA-Chi)

    Article • Journal of Colloid and Interface Science, May 2015, Elsevier

    Assistant Professor Saeed Alqahtani

  36. ATP-binding cassette subfamily B member 1 (ABCB1) and subfamily C member 10 (ABCC10) are not primary resistance factors for cabazitaxel

    Article • Chinese Journal of Cancer, March 2015, Springer Science + Business Media

    Assistant Professor Saeed Alqahtani

  37. Vitamin E Transporters in Cancer Therapy

    Article • The AAPS Journal, December 2014, Springer Science + Business Media

    Assistant Professor Saeed Alqahtani

  38. The small molecule tyrosine kinase inhibitor NVP-BHG712 antagonizes ABCC10-mediated paclitaxel resistance: a preclinical and pharmacokinetic study

    Article • Oncotarget, October 2014, Impact Journals, LLC

    Assistant Professor Saeed Alqahtani

  39. Enhanced Solubility and Oral Bioavailability of γ‐Tocotrienol Using a Self‐Emulsifying Drug Delivery System (SEDDS)

    Article • Lipids, June 2014, Wiley

    Assistant Professor Saeed Alqahtani

  40. Effect of PEG Surface Conformation on Anticancer Activity and Blood Circulation of Nanoemulsions Loaded with Tocotrienol-Rich Fraction of Palm Oil

    Article • The AAPS Journal, August 2013, Springer Science + Business Media

    Assistant Professor Saeed Alqahtani

  41. Experimental models for predicting drug absorption and metabolism

    Article • Expert Opinion on Drug Metabolism & Toxicology, May 2013, Informa Healthcare

    Assistant Professor Saeed Alqahtani , Prof Mohamed Abdel-Latif

  42. Nonlinear Absorption Kinetics of Self-Emulsifying Drug Delivery Systems (SEDDS) Containing Tocotrienols as Lipophilic Molecules: In Vivo and In Vitro Studies

    Article • The AAPS Journal, April 2013, Springer Science + Business Media

    Assistant Professor Saeed Alqahtani