All Stories

  1. The potential neuroprotective effects of saffron carotenoids in a streptozotocin-induced rat model of Alzheimer's disease Behavioral and Biochemical Improvements, and the Activation of Akt/GSK3β/Nrf2 Signaling Pathway
  2. Natural C20 Carotenoids Protect dPC12 Cells from Aβ-Induced Cell Cycle Re-entry, Tau Phosphorylation, and Nrf2 Activation via the Akt/GSK-3β Pathway
  3. Correction: Aghaei et al. The Role of BiP and the IRE1α-XBP1 Axis in Rhabdomyosarcoma Pathology. Cancers 2021, 13, 4927
  4. Retraction Note: Serum melatonin levels and in a sample of Iranian patients with migraine
  5. RETRACTED ARTICLE: Serum melatonin levels and in a sample of Iranian patients with migraine
  6. Cadmium nanocluster as a safe nanocarrier: biodistribution in BALB/c mice and application to carry crocin to breast cancer cell lines
  7. Co-administration of “L-Lysine, Vitamin C, and Zinc” increased the antioxidant activity, decreased insulin resistance, and improved lipid profile in streptozotocin-induced diabetic rats
  8. Saffron carotenoids reversed the UCMS-induced depression and anxiety in rats: Behavioral and biochemical parameters, and hippocampal BDNF/ERK/CREB and NR2B signaling markers
  9. The size of human subcutaneous adipocytes, but not adiposity, is associated with inflammation, endoplasmic reticulum stress, and insulin resistance markers
  10. Protective effect of saffron carotenoids against amyloid beta‐induced neurotoxicity in differentiated PC12 cells via the unfolded protein response and autophagy
  11. Proteomics analysis revealed the presence of inflammatory and oxidative stress markers in the plasma of migraine patients during the pain period
  12. Crocetin ameliorates non-alcoholic fatty liver disease by modulating mitochondrial dysfunction in L02 cells and zebrafish model
  13. The Role of BiP and the IRE1α–XBP1 Axis in Rhabdomyosarcoma Pathology
  14. L-lysine supplementation improved glycemic control, decreased protein glycation, and insulin resistance in type 2 diabetic patients
  15. L-lysine protects C2C12 myotubes and 3T3-L1 adipocytes against high glucose damages and stresses
  16. Interaction of saffron carotenoids with catalase: in vitro, in vivo and molecular docking studies
  17. Prevention of α-crystallin glycation and aggregation using l-lysine results in the inhibition of in vitro catalase heat-induced-aggregation and suppression of cataract formation in the diabetic rat
  18. The effect of crocetin supplementation on markers of atherogenic risk in patients with coronary artery disease: a pilot, randomized, double-blind, placebo-controlled clinical trial
  19. Different Pain States of Trigeminal Neuralgia Make Significant Changes in the Plasma Proteome and Some Biochemical Parameters: a Preliminary Cohort Study
  20. Erratum to: Cadmium nanoclusters in a protein matrix: Synthesis, characterization, and application in targeted drug delivery and cellular imaging
  21. Saffron as a functional food and a nutraceutical using saffron and its constituents as the nutraceutics to protect against chronic diseases
  22. Isolation and characterization of the primary epithelial breast cancer cells and the adjacent normal epithelial cells from Iranian women’s breast cancer tumors
  23. Homogenate Extraction of Crocins from Saffron Optimized by Response Surface Methodology
  24. Effects of Saffron Aqueous Extract and Its Main Constituent, Crocin, on Health-Related Quality of Life, Depression, and Sexual Desire in Coronary Artery Disease Patients: A Double-Blind, Placebo-Controlled, Randomized Clinical Trial
  25. A mechanical, in vitro study of saffron carotenoids (crocin) function.
  26. Mevalonate Pathway and Human Cancers
  27. Bioinformatic prediction and experimental validation of a PE38-based recombinant immunotoxin targeting the Fn14 receptor in cancer cells
  28. BSA-templated Pb Nanocluster as a Biocompatible Signaling Probe for Electrochemical EGFR Immunosensing
  29. The synergistic effect of antiglycating agents (MB-92) on inhibition of protein glycation, misfolding and diabetic complications in diabetic-atherosclerotic rat
  30. Cadmium nanoclusters in a protein matrix: Synthesis, characterization, and application in targeted drug delivery and cellular imaging
  31. Preparation of a new nanobiosensor for the determination of some biogenic polyamines and investigation of their interaction with DNA
  32. Inhibitory Effect of Crocin(s) on Lens α-Crystallin Glycation and Aggregation, Results in the Decrease of the Risk of Diabetic Cataract
  33. OUP accepted manuscript
  34. Electrochemical aptamer/antibody based sandwich immunosensor for the detection of EGFR, a cancer biomarker, using gold nanoparticles as a signaling probe
  35. Effect of Crocin on Cell Cycle Regulators in N-Nitroso-N-Methylurea-Induced Breast Cancer in Rats
  36. Probing redox reaction of azurin protein immobilized on hydroxyl-terminated self-assembled monolayers with different lengths
  37. How Phytochemicals Prevent Chemical Carcinogens and/or Suppress Tumor Growth?
  38. Preface
  39. Chemo-immunotherapy using saffron and its ingredients followed by E7-NT (gp96) DNA vaccine generates different anti-tumor effects against tumors expressing the E7 protein of human papillomavirus
  40. Comparative study of the interaction of meso-tetrakis (N-para-trimethyl-anilium) porphyrin (TMAP) in its free base and Fe derivative form with oligo(dA.dT)15and oligo(dG.dC)15
  41. Recent progress in the study of the Rheb family GTPases
  42. l-cysteine is a potent inhibitor of protein glycation on both albumin and LDL, and prevents the diabetic complications in diabetic–atherosclerotic rat
  43. Saffron Aqueous Extract Prevents Metabolic Syndrome in Patients with Schizophrenia on Olanzapine Treatment: A Randomized Triple Blind Placebo Controlled Study
  44. Design and characterization of a chimeric multiepitope construct containing CfaB, heat-stable toxoid, CssA, CssB, and heat-labile toxin subunit B of enterotoxigenicEscherichia coli: a bioinformatic approach
  45. A review of the chemistry and uses of crocins and crocetin, the carotenoid natural dyes in saffron, with particular emphasis on applications as colorants including their use as biological stains
  46. Anticancer Effect and Molecular Targets of Saffron Carotenoids
  47. Introduction
  48. Preface
  49. Retinoids and their biological effects against cancer
  50. Saffron and natural carotenoids: Biochemical activities and anti-tumor effects
  51. Anticancer effects of crocetin in both human adenocarcinoma gastric cancer cells and rat model of gastric cancer
  52. Crocin improved locomotor function and mechanical behavior in the rat model of contused spinal cord injury through decreasing calcitonin gene related peptide (CGRP)
  53. Interaction Between DNA and Some Salicylic Acid Derivatives and Characterization of Their DNA Targets
  54. Dual-frequency ultrasound activation of nanomicellar doxorubicin in targeted tumor chemotherapy
  55. Effect of fractionation on treatment outcome in local dual-frequency sonication and Dox-encapsulated nanomicelles
  56. Crocin Triggers the Apoptosis Through Increasing the Bax/Bcl-2 Ratio and Caspase Activation in Human Gastric Adenocarcinoma, AGS, Cells
  57. The protective effect of crocin on the amyloid fibril formation of aβ42 peptide in vitro
  58. Is There Any Interaction Between Telomeric DNA Structures, G-Quadruplex and I-Motif, with Saffron Active Metabolites?
  59. A new DNA-nanobiosensor based on G-quadruplex immobilized on carbon nanotubes modified glassy carbon electrode
  60. Effect of Crocin on the Insulin Resistance and Lipid Profile of Streptozotocin‐Induced Diabetic Rats
  61. Investigation of the mechanism(s) involved in decreasing increased fibrinogen activity in hyperglycemic conditions using L-lysine supplementation
  62. Mechanisms of the Effects of Crocin on Aggregation and Deposition of Aβ1–40 Fibrils in Alzheimer’s Disease
  63. In Situ Synthesis of a Novel Quinone Imine Self-Assembled Monolayer and Consideration of Its Reactivity with L-Arginine
  64. The dual behavior of heat shock protein 70 and asymmetric dimethylarginine in relation to serum CRP levels in type 2 diabetes
  65. Effect of Chemical Chaperones on Glucose-Induced Lysozyme Modifications
  66. Effect of local dual frequency sonication on drug distribution from polymeric nanomicelles
  67. A Noninvasive Method for Early Detection of MNNG-Induced Gastric Cancer of Male Wistar rat: Ultrasonic Study
  68. DNA immobilization on a polypyrrole nanofiber modified electrode and its interaction with salicylic acid/aspirin
  69. Comparison of the Chaperoning Action of Glycerol and β-Casein on Aggregation of Proteins in the Presence of Crowding Agent
  70. Histone H1 Structural Changes and its Interaction with DNA in the Presence of High Glucose ConcentrationIn VivoandIn Vitro
  71. Enhancement and control of acoustic cavitation yield by low-level dual frequency sonication: A subharmonic analysis
  72. Spectroscopic studies of the interaction of aspirin and its important metabolite, salicylate ion, with DNA, A·T and G·C rich sequences
  73. New Applications and Mechanisms of Action of Saffron and its Important Ingredients
  74. The effect of hot-tub therapy on serum Hsp70 level and its benefit on diabetic rats: A preliminary report
  75. Preparation, purification and virus inactivation of intravenous immunoglobulin from human plasma
  76. Evaluation of correlation between chemical dosimetry and subharmonic spectrum analysis to examine the acoustic cavitation
  77. Treatment of Murine Tumors Using Dual-Frequency Ultrasound in an Experimental in Vivo Model
  78. Electrochemical DNA nano-biosensor for the study of spermidine–DNA interaction
  79. Interaction of Safranal and Picrocrocin with ctDNA and Their Preferential Mechanisms of Binding to GC- and AT-Rich Oligonucleotides
  80. Spectroscopic studies of STZ-induced methylated-DNA in both in vivo and in vitro conditions
  81. Electrochemically fabricated polypyrrole nanofiber-modified electrode as a new electrochemical DNA biosensor
  82. Electrochemical studies of DNA immobilization onto the azide-terminated monolayers and its interaction with taxol
  83. Structural study on immunoglobulin G solution after pasteurization with and without stabilizer
  84. Effect of spermine on lipid profile and HDL functionality in the streptozotocin-induced diabetic rat model
  85. Investigation of the Mechanisms Involved in the High-Dose and Long-Term Acetyl Salicylic Acid Therapy of Type I Diabetic Rats
  86. Effect of exposure parameters on cavitation induced by low-level dual-frequency ultrasound
  87. Interaction of Saffron Carotenoids as Anticancer Compounds with ctDNA, Oligo (dG.dC)15, and Oligo (dA.dT)15
  88. Interaction of an Fe derivative of TMAP (Fe(TMAP)OAc) with DNA in comparison with free-base TMAP
  89. Theoretical investigation on the binding of lysine-containing peptides with dodecyl sulfate ion using semi-empirical calculations
  90. The improvement effect ofL-Lys as a chemical chaperone on STZ-induced diabetic rats, protein structure and function
  91. Studies of thermostability in Camelus bactrianus (Bactrian camel) single-domain antibody specific for the mutant epidermal-growth-factor receptor expressed by Pichia
  92. Electrocatalytic oxidation of glucose at a Ni-curcumin modified glassy carbon electrode
  93. The effect of post-burn local hyperthermia on the reducing burn injury: The possible role of opioids
  94. An electrochemical study of neutral red–DNA interaction
  95. The effect of carotenoids obtained from saffron on histone H1 structure and H1–DNA interaction
  96. A novel potentiometric sensor for selective determination of theophylline: Theoretical and practical investigations
  97. Electrochemical investigation of neutral red binding to DNA at the surface
  98. Immunosuppressive activity of a molecule isolated from Artemisia annua on DTH responses compared with cyclosporin A
  99. Semi-empirical quantum chemical study of the interactions between lysine, arginine and histidine with a homologue set of n-alkyl sulfates in the gas phase and aqueous solution
  100. Microcalorimetry, energetics and binding studies of DNA–dimethyltin dichloride complexes
  101. DNA as an enzyme
  102. A mechanistic study of the histone H1-DNA complex dissociation by sodium dodecyl sulfate
  103. Studies on mechanism of 8-methoxypsoralen–DNA interaction in the dark
  104. Energetic and binding properties of DNA upon interaction with dodecyl trimethylammonium bromide