All Stories

  1. Apolipoprotein C-II and C-III preferably transfer to both high-density lipoprotein (HDL)2 and the larger HDL3 from very low-density lipoprotein (VLDL)

    Article • Biological Chemistry, December 2020, De Gruyter

    Ryunosuke Ohkawa

  2. Red blood cells participate in reverse cholesterol transport by mediating cholesterol efflux of high-density lipoprotein and apolipoprotein A-I from THP-1 macrophages

    Article • Biological Chemistry, June 2019, De Gruyter

    Ryunosuke Ohkawa

  3. Serum amyloid A does not affect high-density lipoprotein cholesterol measurement by a homogeneous assay

    Article • Clinical Biochemistry, January 2019, Elsevier

    Ryunosuke Ohkawa

  4. Characterization of the cholesterol efflux of apolipoprotein E-containing high-density lipoprotein

    Article • Biological Chemistry, September 2018, De Gruyter

    Ryunosuke Ohkawa

  5. Measurement of plasma choline in acute coronary syndrome: importance of suitable sampling conditions for this assay

    Article • Scientific Reports, March 2018, Springer Science + Business Media

    Ryunosuke Ohkawa

  6. Prognostic impact of homocysteine levels and homocysteine thiolactonase activity on long-term clinical outcomes in patients undergoing percutaneous coronary intervention

    Article • Journal of Cardiology, June 2017, Elsevier

    Ryunosuke Ohkawa

  7. Different origins of lysophospholipid mediators between coronary and peripheral arteries in acute coronary syndrome

    Article • Journal of Lipid Research, December 2016, American Society for Biochemistry & Molecular Biology (ASBMB)

    Ryunosuke Ohkawa

  8. Effects of serum amyloid A on the structure and antioxidant ability of high-density lipoprotein

    Article • Bioscience Reports, July 2016, Portland Press Ltd.

    Ryunosuke Ohkawa

  9. Regulation of the lysophosphatidylserine and sphingosine 1-phosphate levels in autologous whole blood by the pre-storage leukocyte reduction

    Article • Transfusion Medicine, June 2016, Wiley

    Ryunosuke Ohkawa

  10. Cholesterol Efflux Capacity of Apolipoprotein A-I Varies with the Extent of Differentiation and Foam Cell Formation of THP-1 Cells

    Article • Journal of Lipids, January 2016, Hindawi Publishing Corporation

    Ryunosuke Ohkawa

  11. High-Density Lipoprotein Binds toMycobacterium aviumand Affects the Infection of THP-1 Macrophages

    Article • Journal of Lipids, January 2016, Hindawi Publishing Corporation

    Ryunosuke Ohkawa

  12. Serum Autotaxin Levels Are Associated with Proteinuria and Kidney Lesions in Japanese Type 2 Diabetic Patients with Biopsy-proven Diabetic Nephropathy

    Article • Internal Medicine, January 2016, Japanese Society of Internal Medicine

    Ryunosuke Ohkawa

  13. Possible involvement of sphingomyelin in the regulation of the plasma sphingosine 1-phosphate level in human subjects

    Article • Clinical Biochemistry, July 2015, Elsevier

    Ryunosuke Ohkawa

  14. Possible Involvement of Minor Lysophospholipids in the Increase in Plasma Lysophosphatidic Acid in Acute Coronary Syndrome

    Article • Arteriosclerosis Thrombosis and Vascular Biology, February 2015, Wolters Kluwer Health

    Ryunosuke Ohkawa

  15. Effects of Myeloperoxidase-Induced Oxidation on Antiatherogenic Functions of High-Density Lipoprotein

    Article • Journal of Lipids, January 2015, Hindawi Publishing Corporation

    Ryunosuke Ohkawa

  16. LDL Receptor and ApoE Are Involved in the Clearance of ApoM-associated Sphingosine 1-Phosphate

    Article • Journal of Biological Chemistry, December 2014, American Society for Biochemistry & Molecular Biology (ASBMB)

    Ryunosuke Ohkawa

  17. ENPP2 Contributes to Adipose Tissue Expansion and Insulin Resistance in Diet-Induced Obesity

    Article • Diabetes, June 2014, American Diabetes Association

    Ryunosuke Ohkawa

  18. Increased serum autotaxin levels in hepatocellular carcinoma patients were caused by background liver fibrosis but not by carcinoma

    Article • Clinica Chimica Acta, June 2014, Elsevier

    Ryunosuke Ohkawa

  19. TNF-α production in NKT cell hybridoma is regulated by sphingosine-1-phosphate

    Article • Coronary Artery Disease, June 2014, Wolters Kluwer Health

    Ryunosuke Ohkawa

  20. Detection of Novel Visible-Light Region Absorbance Peaks in the Urine after Alkalization in Patients with Alkaptonuria

    Article • PLOS One, January 2014, PLOS

    Ryunosuke Ohkawa

  21. Increased serum mitochondrial creatine kinase activity as a risk for hepatocarcinogenesis in chronic hepatitis C patients

    Article • International Journal of Cancer, January 2014, Wiley

    Ryunosuke Ohkawa

  22. Platelet-derived sphingosine 1-phosphate induces migration of Jurkat T cells

    Article • Lipids in Health and Disease, January 2014, Springer Science + Business Media

    Ryunosuke Ohkawa

  23. High ubiquitous mitochondrial creatine kinase expression in hepatocellular carcinoma denotes a poor prognosis with highly malignant potential

    Article • International Journal of Cancer, October 2013, Wiley

    Ryunosuke Ohkawa

  24. Increased plasma sphingosine-1-phosphate in obese individuals and its capacity to increase the expression of plasminogen activator inhibitor-1 in adipocytes

    Article • Coronary Artery Disease, September 2013, Wolters Kluwer Health

    Ryunosuke Ohkawa

  25. Necessity of Lysophosphatidic Acid Receptor 1 for Development of Arthritis

    Article • Arthritis & Rheumatism, July 2013, Wiley

    Ryunosuke Ohkawa

  26. Impact of immunoreactive substances contained in apheresis platelet concentrate on postoperative respiratory function in surgical patients receiving platelet transfusion: a prospective cohort study

    Article • Transfusion Medicine, July 2013, Wiley

    Ryunosuke Ohkawa

  27. Increased lysophosphatidic acid levels in culprit coronary arteries of patients with acute coronary syndrome

    Article • Atherosclerosis, July 2013, Elsevier

    Ryunosuke Ohkawa

  28. Liver involvement in sphingosine 1-phosphate dynamism revealed by adenoviral hepatic overexpression of apolipoprotein M

    Article • Atherosclerosis, July 2013, Elsevier

    Ryunosuke Ohkawa

  29. Inhibition of lysophosphatidic acid increase by prestorage whole blood leukoreduction in autologous CPDA-1 whole blood

    Article • Transfusion, March 2013, Wiley

    Ryunosuke Ohkawa

  30. Decrease in circulating autotaxin by oral administration of prednisolone

    Article • Clinica Chimica Acta, January 2013, Elsevier

    Ryunosuke Ohkawa

  31. Plasma lysophosphatidic acid levels and hepatocellular carcinoma

    Article • Hepatology, January 2013, Wiley

    Ryunosuke Ohkawa

  32. Sphingosine 1-phosphate release from platelets during clot formation: close correlation between platelet count and serum sphingosine 1-phosphate concentration

    Article • Lipids in Health and Disease, January 2013, Springer Science + Business Media

    Ryunosuke Ohkawa

  33. Development of an enzymatic assay for sphingomyelin with rapid and automatable performances: Analysis in healthy subjects and coronary heart disease patients

    Article • Clinical Biochemistry, November 2012, Elsevier

    Ryunosuke Ohkawa

  34. Higher lipoprotein-associated phospholipase A2 levels are associated with coronary atherosclerosis documented by coronary angiography

    Article • Annals of Clinical Biochemistry International Journal of Laboratory Medicine, August 2012, SAGE Publications

    Ryunosuke Ohkawa

  35. Increased activity of serum mitochondrial isoenzyme of creatine kinase in hepatocellular carcinoma patients predominantly with recurrence

    Article • Journal of Hepatology, August 2012, Elsevier

    Ryunosuke Ohkawa

  36. Serum Autotaxin is not a Useful Biomarker for Ovarian Cancer

    Article • Lipids, June 2012, Wiley

    Ryunosuke Ohkawa

  37. Analytical evaluation of plasma serotonin and sphingosine 1-phosphate and their clinical assessment in early atherosclerosis

    Article • Coronary Artery Disease, June 2012, Wolters Kluwer Health

    Ryunosuke Ohkawa

  38. Increased circulating plasma lysophosphatidic acid in patients with acute coronary syndrome

    Article • Clinica Chimica Acta, January 2012, Elsevier

    Ryunosuke Ohkawa

  39. Decreased circulating lipoprotein-associated phospholipase A2 levels are associated with coronary plaque regression in patients with acute coronary syndrome

    Article • Atherosclerosis, December 2011, Elsevier

    Ryunosuke Ohkawa

  40. Serum autotaxin measurements in pregnant women: Application for the differentiation of normal pregnancy and pregnancy-induced hypertension

    Article • Clinica Chimica Acta, October 2011, Elsevier

    Ryunosuke Ohkawa

  41. Autotaxin as a novel serum marker of liver fibrosis

    Article • Clinica Chimica Acta, June 2011, Elsevier

    Ryunosuke Ohkawa

  42. Sphingosine-1-phosphate receptor-2 deficiency leads to inhibition of macrophage proinflammatory activities and atherosclerosis in apoE-deficient mice

    Article • Journal of Clinical Investigation, November 2010, American Society for Clinical Investigation

    Ryunosuke Ohkawa

  43. A novel enzyme immunoassay for the determination of phosphatidylserine-specific phospholipase A1 in human serum samples

    Article • Clinica Chimica Acta, August 2010, Elsevier

    Ryunosuke Ohkawa

  44. Plasma concentration of bioactive lipid mediator sphingosine 1-phosphate is reduced in patients with chronic hepatitis C

    Article • Clinica Chimica Acta, May 2010, Elsevier

    Ryunosuke Ohkawa

  45. Sustained delivery of sphingosine-1-phosphate using poly(lactic-co-glycolic acid)-based microparticles stimulates Akt/ERK-eNOS mediated angiogenesis and vascular maturation restoring blood flow in ischemic limbs of mice

    Article • European Journal of Pharmacology, May 2010, Elsevier

    Ryunosuke Ohkawa

  46. Unbalanced expression of sphingosine 1-phosphate receptors in diabetic nephropathy

    Article • Experimental and Toxicologic Pathology, January 2010, Elsevier

    Ryunosuke Ohkawa

  47. Impact of fresh-frozen plasma from male-only donors versus mixed-sex donors on postoperative respiratory function in surgical patients: a prospective case-controlled study

    Article • Transfusion, November 2009, Wiley

    Ryunosuke Ohkawa

  48. Autotaxin enzyme immunoassay in human cerebrospinal fluid samples

    Article • Clinica Chimica Acta, July 2009, Elsevier

    Ryunosuke Ohkawa

  49. Antagonism of Sphingosine 1-Phosphate Receptor-2 Enhances Migration of Neural Progenitor Cells Toward an Area of Brain Infarction

    Article • Stroke, December 2008, Wolters Kluwer Health

    Ryunosuke Ohkawa

  50. Serum autotaxin measurement in haematological malignancies: a promising marker for follicular lymphoma

    Article • British Journal of Haematology, October 2008, Wiley

    Ryunosuke Ohkawa

  51. Measurement of plasma lysophosphatidic acid concentration in healthy subjects: strong correlation with lysophospholipase D activity

    Article • Annals of Clinical Biochemistry International Journal of Laboratory Medicine, July 2008, SAGE Publications

    Ryunosuke Ohkawa

  52. Plasma sphingosine-1-phosphate measurement in healthy subjects: close correlation with red blood cell parameters

    Article • Annals of Clinical Biochemistry International Journal of Laboratory Medicine, July 2008, SAGE Publications

    Ryunosuke Ohkawa

  53. Validation of an autotaxin enzyme immunoassay in human serum samples and its application to hypoalbuminemia differentiation

    Article • Clinica Chimica Acta, February 2008, Elsevier

    Ryunosuke Ohkawa

  54. Analysis of serum and urinary lysophospholipase D/autotaxin in nephrotic syndrome

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), January 2008, De Gruyter

    Ryunosuke Ohkawa

  55. Serum lysophospholipase D/autotaxin may be a new nutritional assessment marker: study on prostate cancer patients

    Article • Annals of Clinical Biochemistry International Journal of Laboratory Medicine, November 2007, SAGE Publications

    Ryunosuke Ohkawa

  56. Plasma lysophosphatidic acid level and serum autotaxin activity are increased in liver injury in rats in relation to its severity

    Article • Life Sciences, September 2007, Elsevier

    Ryunosuke Ohkawa

  57. Suppression of lysophosphatidic acid and lysophosphatidylcholine formation in the plasma in vitro: Proposal of a plasma sample preparation method for laboratory testing of these lipids

    Article • Analytical Biochemistry, August 2007, Elsevier

    Ryunosuke Ohkawa

  58. Both Plasma Lysophosphatidic Acid and Serum Autotaxin Levels are Increased in Chronic Hepatitis C

    Article • Journal of Clinical Gastroenterology, July 2007, Wolters Kluwer Health

    Ryunosuke Ohkawa

  59. Lysophosphatidic acid protection against apoptosis in the human pre-B-cell line Nalm-6

    Article • European Journal Of Haematology, June 2007, Wiley

    Ryunosuke Ohkawa

  60. Measurement of lysophospholipase D/autotaxin activity in human serum samples

    Article • Clinical Biochemistry, February 2007, Elsevier

    Ryunosuke Ohkawa

  61. Lysophospholipase D activity exists in the urine to catalyse the formation of lysophosphatidic acid

    Article • Nephrology Dialysis Transplantation, September 2006, Oxford University Press (OUP)

    Ryunosuke Ohkawa

  62. Essential Roles of Sphingosine 1-Phosphate/S1P1Receptor Axis in the Migration of Neural Stem Cells Toward a Site of Spinal Cord Injury

    Article • Stem Cells, September 2006, Wiley

    Ryunosuke Ohkawa

  63. Autotaxin Stabilizes Blood Vessels and Is Required for Embryonic Vasculature by Producing Lysophosphatidic Acid

    Article • Journal of Biological Chemistry, July 2006, American Society for Biochemistry & Molecular Biology (ASBMB)

    Ryunosuke Ohkawa

  64. Platelet release of β-thromboglobulin and platelet factor 4 and serotonin in plasma samples

    Article • Clinical Biochemistry, November 2005, Elsevier

    Ryunosuke Ohkawa